Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   
Gene: RAPGEF5 (Rap guanine nucleotide exchange factor 5) Homo sapiens
Analyze
Symbol: RAPGEF5
Name: Rap guanine nucleotide exchange factor 5
Description: Exhibits GTP-dependent protein binding activity and Rap guanyl-nucleotide exchange factor activity. Predicted to be involved in small GTPase mediated signal transduction. Localizes to the nuclear body.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: GFR; guanine nucleotide exchange factor for Rap1; KIAA0277; M-Ras-regulated GEF; M-Ras-regulated Rap GEF; MR-GEF; Rap guanine nucleotide exchange factor (GEF) 5; related to Epac; REPAC
Orthologs:
Mus musculus (house mouse) : Rapgef5 (Rap guanine nucleotide exchange factor (GEF) 5)  MGI  Alliance
Rattus norvegicus (Norway rat) : Rapgef5 (Rap guanine nucleotide exchange factor 5)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Rapgef5 (Rap guanine nucleotide exchange factor 5)
Pan paniscus (bonobo/pygmy chimpanzee) : RAPGEF5 (Rap guanine nucleotide exchange factor 5)
Canis lupus familiaris (dog) : RAPGEF5 (Rap guanine nucleotide exchange factor 5)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Rapgef5 (Rap guanine nucleotide exchange factor 5)
Sus scrofa (pig) : RAPGEF5 (Rap guanine nucleotide exchange factor 5)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38 Ensembl722,118,236 - 22,357,154 (-)Ensembl
GRCh38722,118,236 - 22,357,154 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh37722,157,908 - 22,396,751 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36722,124,433 - 22,363,058 (-)NCBINCBI36hg18NCBI36
Celera722,143,557 - 22,382,091 (-)NCBI
Cytogenetic Map7p15.3NCBI
HuRef722,043,471 - 22,243,092 (-)NCBIHuRef
CHM1_1722,158,708 - 22,397,156 (-)NCBICHM1_1
CRA_TCAGchr7v2722,209,210 - 22,447,742 (-)NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
Nomenclature History
 
More on RAPGEF5
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1343059
Created: 2005-03-08
Species: Homo sapiens
Last Modified: 2019-12-25
Status: ACTIVE



NHLBI Logo

RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.