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Gene: RAPGEF5 (Rap guanine nucleotide exchange factor 5) Chlorocebus sabaeus

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Symbol:

RAPGEF5

Name:

Rap guanine nucleotide exchange factor 5

RGD ID:

18711846

Description:

ENCODES a protein that exhibits GTP-dependent protein binding (ortholog); INVOLVED IN Ras protein signal transduction (inferred); small GTPase-mediated signal transduction (inferred); ASSOCIATED WITH amphetamine abuse (ortholog); dilated cardiomyopathy 1A (ortholog); hypomyelinating leukodystrophy 5 (ortholog); FOUND IN nucleus (ortholog)

Type:

protein-coding

RefSeq Status:

RGD Orthologs

Alliance Orthologs

More Info

more info ...

Latest Assembly:

ChlSab1.1 - Green Monkey 1.1 Assembly

Position:

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	21	35,894,481 - 36,132,041 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	21	35,940,360 - 36,133,715 (+)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666042	68,454,107 - 68,689,515 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

amphetamine abuse (ISO)

dilated cardiomyopathy 1A (ISO)

hypomyelinating leukodystrophy 5 (ISO)

pleomorphic xanthoastrocytoma (ISO)

primary ciliary dyskinesia (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

Ras protein signal transduction (IEA)

small GTPase-mediated signal transduction (IEA)

Cellular Component

nuclear body (IEA)

nucleoplasm (IEA)

nucleus (ISO)

plasma membrane (IEA)

Molecular Function

GTP-dependent protein binding (ISO)

guanyl-nucleotide exchange factor activity (IEA)

protein binding (ISO)

References

Additional References at PubMed

PMID:22301074	PMID:30032202

Genomics

Comparative Map Data

RAPGEF5
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	21	35,894,481 - 36,132,041 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	21	35,940,360 - 36,133,715 (+)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666042	68,454,107 - 68,689,515 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

RAPGEF5
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	7	22,118,236 - 22,357,154 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	7	22,118,236 - 22,357,154 (-)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	7	22,157,854 - 22,396,773 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	7	22,124,433 - 22,363,058 (-)	NCBI	NCBI36	Build 36	hg18	NCBI36
Celera	7	22,143,557 - 22,382,091 (-)	NCBI		Celera
Cytogenetic Map	7	p15.3	NCBI
HuRef	7	22,043,471 - 22,243,092 (-)	NCBI		HuRef
CHM1_1	7	22,158,708 - 22,397,156 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	7	22,254,475 - 22,493,270 (-)	NCBI		T2T-CHM13v2.0
CRA_TCAGchr7v2	7	22,209,210 - 22,447,742 (-)	NCBI

Rapgef5
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	12	117,480,146 - 117,723,472 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	12	117,480,099 - 117,723,472 (+)	Ensembl		GRCm39 Ensembl
GRCm38	12	117,516,526 - 117,759,737 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	12	117,516,479 - 117,759,737 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	12	118,754,952 - 118,995,451 (+)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	12	117,958,488 - 118,198,654 (+)	NCBI		MGSCv36	mm8
MGSCv36	12	111,717,001 - 111,958,157 (+)	NCBI		MGSCv36	mm8
Cytogenetic Map	12	F2	NCBI
cM Map	12	63.06	NCBI

Rapgef5
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	6	144,588,162 - 144,822,908 (+)	NCBI		GRCr8
mRatBN7.2	6	138,445,184 - 138,679,943 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	6	138,437,991 - 138,679,936 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	6	141,880,425 - 142,115,425 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	6	138,497,846 - 138,732,849 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	6	139,052,896 - 139,287,512 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	6	145,387,890 - 145,625,243 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	6	145,546,595 - 145,625,236 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	6	154,308,057 - 154,541,118 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	6	144,949,908 - 145,030,090 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
Celera	6	136,254,550 - 136,332,824 (+)	NCBI		Celera
Cytogenetic Map	6	q33	NCBI

Rapgef5
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955410	24,525,748 - 24,716,372 (-)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955410	24,525,748 - 24,716,151 (-)	NCBI	ChiLan1.0	ChiLan1.0

RAPGEF5
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	6	26,984,630 - 27,225,479 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	7	75,309,356 - 75,550,210 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	7	22,806,855 - 23,047,663 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	7	22,118,332 - 22,317,650 (-)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	7	22,122,434 - 22,317,650 (-)	Ensembl	panpan1.1		panPan2

RAPGEF5
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	14	35,979,393 - 36,208,849 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	14	35,982,444 - 36,209,214 (-)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	14	35,520,950 - 35,750,469 (-)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	14	35,904,738 - 36,135,155 (-)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	14	35,904,768 - 36,135,551 (-)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	14	36,024,971 - 36,254,867 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	14	35,721,839 - 35,951,074 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	14	36,057,456 - 36,287,333 (-)	NCBI		UU_Cfam_GSD_1.0

Rapgef5
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024405118	80,185,677 - 80,381,255 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936546	7,864,608 - 8,051,356 (-)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936546	7,860,795 - 8,051,351 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

RAPGEF5
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	9	90,958,078 - 91,578,992 (-)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	9	90,958,078 - 91,232,256 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	9	100,401,677 - 100,899,598 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

Rapgef5
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624739	8,427,796 - 8,610,694 (+)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624739	8,388,172 - 8,614,469 (+)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Variants

Variants in RAPGEF5
5010 total Variants

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

ectoderm	endocrine system	hemolymphoid system	mesenchyme	mesoderm	nervous system	reproductive system
76	36	20	36	36	60	20

Sequence

Nucleotide Sequences


RefSeq Transcripts	XM_007981904	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_007981905	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038004733	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038004734	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	JACDXN010000010	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSCSAT00000011990 ⟹ ENSCSAP00000010043

Type:

CODING

Position:

Green Monkey Assembly	Chr	Position (strand)	Source
ChlSab1.1 Ensembl	21	35,940,360 - 36,133,715 (+)	Ensembl

RefSeq Acc Id:

XM_007981904 ⟹ XP_007980095

Type:

CODING

Position:

Green Monkey Assembly	Chr	Position (strand)	Source
ChlSab1.1	21	35,894,481 - 36,132,041 (+)	NCBI
Vero_WHO_p1.0	NW_023666042	68,454,107 - 68,689,515 (-)	NCBI

Sequence:

show sequence

GGCCGCGGCGCGCGCCAATGGGCAGCGGCTGGCAGCGCGCCCCGCGCCCGAGCTGCAGTCGCGC
CCTCTCGCTTCCTGGCGAAGGCGCGGACGGCGCGCGGAGGCGAGCGCGGTAGAGAGAGGAGCCC
CCGGCGCCGCAGCGCCGTCAGGGCATGAGGATGGCAGTGGGCTCCGTCAAGATGCAGCCGCCGT
GCGAGAGCCCGGCCCTAGCTGCCGCGGCGGCAGTGGTGGCGGCAGACGGCGCCCTGCGCCGCAG
CCCCAGCGCCCGGGAGCCCGAGCGCGAGCAGCCGCCGGCGTCGCTGCGGCCGCGGCTGAGGGAC
CTGCCCGCGCTGCTGCGGAGCGGGCTCACGCTGCGGAGGAAGCGGAGCGCCGCTGGGGGCCGGA
CTCTATCAAGAAGAATATCTAATCCGTACCTTGAACATACGCCTTCCCAGATTTATGGAGAGAA
TTCTTCTTGTGCAGGAAGAGCACTGAGGAATATTATTATCGTTCAAGCAGCTGACCTGATAAAG
GACAGAGTGAACCTCAAGGGGTTTTACAGGAGGAGCTGCGTCGGGTCAGAACTGGTAGACTGGC
TTCTAGAACACTGTCCTTTTGTCCAGTGCAGATCTATGGCCATAGGAGTCTGGCAACTCCTACT
GGACATGGGAATTATGTTATCAGTGGACCAGCATCTATACTTTCAAGATACTTATGTTTTCTAC
CAGTTTTCCTCTGATGAATGTAGCTACTTGTACTGTGAATTTGAAAGAGAAGAAGAATGGCAAA
ATGGTGTCAAGCTTTTACTGCAACTTGTGCCTCTCATTCCTGCTAGAGCTGGCATCTGTGAGCT
GTCTCATCAGAAAATTGAAGACTCTGAAGAAAGCAGTGATGAAATTCTTGCGCGTCTAACATCT
GCGGTGCAGAGAGAGCTAGCAGCTGTGATTGCTTTGAAAGCAAGGAAGTCTGCAATTGAACAAG
ATGAAGAAAACAATGACAAACATGTAGCTGTAACAGAAGCCGAAAGTGTTCCAGATTCTCAGGC
AGGGGTGATGTGCAAGCTTCAAGAAAGAGATGAAATCGGACGAATCGAACTAGTTCAGAAGCTG
GCAAGAGAAAACTATCAGTTTTTGCAGACGGACAAAAAAGAACAGGAGAAGTCTGAACACCAAG
ATGATGAAGTGACGACTGTTCAGGTTAAAGAGCAAGACCAGAGCGTCCTGGTGCTGAAGAAAGT
GCAGTGCTGTGGCCCAGCCCCCACAGCTGGGAGTGCGGAGAGCCATTGGAGATATGTGGTGGTG
TCCGGGACCCCGGAGAAGATTTTGGAGCACCTTTTGAATGACTTGCACCTGGAAGAAGTCCAGG
ACAAAGAAACAGAGACCCTCCTGGATGACTTCCTTCTCACGTACACTGTCTTCATGACAACTGA
TGACTTGTGCCAGGCTCTGTTAAGGCACTATTCCGCTAAGAAGTATCAAGGCAAAGAGGAAAAC
TCAGATGTTCCGCGTAGGAAACGTAAAGTCTTGCATCTTGTTTCCCAGTGGATTGCTCTGTACA
AAGACTGGTTACATGAAGATGAACATTCAAAAATGTTTTTAAAGACCATATATAGGAATGTACT
GGATGATGTTTATGAATATCCAATACTTGAAAAAGAATTGAAAGAATTTCAAAAGATACTTGGA
ATGCACCGTCGTCACACTGTGGATGAATATTCACCACAAAAAAAGAATAAAGCCCTTTTCCACC
AATTCAGTCTTAAGGAGAACTGGCTCCAGCATAGAGGAACTGTGACTGAAACAGAGGAAATTTT
CTGCCACGTGTATATAACAGAGCACTCCTATGTCAGTGTGAAGGCAAAAGTTTCCAGTACAGCC
CAAGAGATCCTAAAATTCGTCGCAGAAAAGATCCAGTATGCTGAAGAGGATCTGGCTCTGGTGG
CCATCACATTCTCTGGAGGAAAGCATGAACTTCAGCCGAATGACTTAGTCATCTCCAAATCCCT
CGAGGCATCTGGTCGGATATATGTCTATCGGAAAGACCTGGCGGACACTTTGAACCCGTTTGCA
GAAAATGAGGAATCACAGCAAAGGTCGATGAGGATTTTGGGAATGAACACTTGGGATCTTGCTC
TGGAATTAATGAATTTTGATTGGAGTCTATTCAATTCAATTCACGAGCAAGAGCTGATCTACTT
CACATTCAGCAGACAGGGAAGTGGGGAACACACTGCAAACCTCAGCCTTCTGCTCCAGAGATGC
AATGAGGTCCAGCTCTGGGTGGCCACGGAGATTCTGCTCTGCAGCCAGCTGGGCAAGCGAGTGC
AGCTGGTGAAAAAATTCATCAAAATTGCGGCTCACTGCAAAGCCCAGAGAAACCTGAATTCTTT
CTTTGCCATCGTGATGGGTCTCAACACTGCTTCTGTCAGTCGACTGTCACAGACCTGGGAGAAA
ATCCCTGGGAAGTTTAAGAAACTTTTCTCTGAACTTGAAAGTTTAACAGATCCTTCCCTAAATC
ACAAAGCCTACAGAGATGCATTCAAAAAGATGAAGCCACCAAAAATCCCTTTCATGCCCTTATT
GCTTAAAGATGTAACATTTATTCATGAAGGAAATAAAACGTTTTTGGATAATCTTGTCAATTTT
GAAAAGCTGCATATGATCGCAGACACTGTCCGAACCCTGAGACACTGCAGGACTAACCAGTTTG
GTGACCTGTGTCCAAAAGAGCATCAAGAGTTAAAGTCCTATGTTAATCACCTATATGTCATTGA
CAGCCAGCAGGCCCTGTTCGAGCTCTCACACAGGATCGAGCCTCGGGTGTGAGCCCCACTGCCT
CACCTCCCCTGTGTCTGCAGCACTTTGAGCTACGGGAATGTCTATGCCAAGCACGTTGCTTTCC
TGTGAGAAAAGAAGTTGCTGAGTTTTATCAGTATAACCCAAGACATTCACAGGAAAGCCAGCCA
AAGCGTGTTCAGGAAGTGATGTCAGCCACCAGAGAGGGGGAGAGGCCTCTCCATGCTACTCTCT
AGACAAGAAGGCAGAAGGAGAGTCAGAAGCATTCTTGAGATGGAGAAGGCTGGTTTCTTACGAT
CACATTGTTGATCCAGTCCAGTTTTCAGTATGAGATGTGCCAGCATCAAGACAAGACAACGACA
TCTTGACATGCAATGACCGAATATTTCATTAAGAGCATGCATGGAACAGGAAGGAGTTTTACTT
TGCCTAGTTTTAGATTACTATCCATAAGCTGTCAAAGAAGTCATTCTTTTGAACACCTGATGAC
AGAGACAGCATCCCTAGATCTCCAGGGAGGAGAGGTTTCTGTTGATACAACGTATGATATCACC
AAAAGCCACTTGTGTCTAGGGAGTTAGTGAGGACTGTAGCTAGCATTCATGCTCTGCTGGGCAG
ATGAACAATGTCAAGGTGTGCATCACTTTGCACCACAATCAACTATTGACACATGCTTGCAAGT
GAAATTAGTTTCTGTACAACTGATTTGCAGCTATAGGCAAGGTAGATGAAGTTGCTTTGCCAGT
AAGGAAAAATAGTAATCTTCAAGAGATTGACTCATTGTTTAATTCCTGGGGATTTTCTTCACAC
TTGTAAGCAGGCTCTTATCTTTTATTGGACATAATATGATTTTGAAAAAGCACAGTGCCTGACA
CATTGTAGACACTCACTAACTGCTTACTGAGGTGACAGAGTCACAAAAGTCTGCATTCTTGTGC
CTGATGATGCATTTTGCATACCTCATACAGGCTCCTTGCCCACACTATGGAATGACAGCAGCCA
GCACAGGGAGGTTAAGTGACATTTAATGAGTGAAGCACTTAGCATTCTCTAGGTAATAAGATAG
CGGTAATTACCAGTGTTTTGGCAAATGAAAAATACCCTGAAATAGCCAAGTGTCTGATTGATGT
TGGTGACTTAGAAGTCCTATAGTCCACCTACCAGCCAAAGCAGGGAGCCTTTCTATAATTTGCC
TTTTTTTTCCCCAAAATCTGAGTCTTCTGAAATCTTTTTTTATTCCCATTTTTACCAATTGAGG
CTCCTTCAGCAAATAAGACCTCTTGATATTTTCAAGGACTGGGTAGAGGATTTCTTTCAACCTT
CACATGAACAAAACAGCCTATGGGTCAAAATAATGAAAGCCACCCCTGCCTGCTAGATACTTGT
CACCTTGCTAAAATGCAAGGGCCTGGTCCATTCATTTTCCAAATGCAGGAGTCTTGGTGCATTT
CTCACTCTTCCTGCCTGTTCATCTCTTTCATGCCCACACAGACCTGTTTCCTTTTTGTCTCATC
AACACCTCATTCATCCTCATTAATGAGGCATGTCCAATGCTTTTTGACATCTTTATAGCAGTGC
TGTTTCCTGGGCTCAGGAACCACACTGAGCGTGAGATACTGCTGGAAGGAACCATGTGGAGAGA
AGGTTTGAGAGGACTTTGAGAGAGACTTAGTTCGGCCCAGCATGTAAAACTTCAGTCCTGAACA
TTTACGGGGTTTTATAGACGGGCATCCTCCAGGGCTGGTCCCTTCAGAGAAATGCTGCATGCTG
CTGGTCATGGAATGTGGCCCACAGGAGGACACCAGAGCCATGAGAACCGGACAGCAGACTTCCC
TCACAGCTGGGCTGAGCAAACCCTCCAAAGCCCTCCTCACACAGTTACTAGCGATAGCATGGGC
TTACAGCACAAGCACGTGTGCTCACCTTTTTCCCATGCACTGGACTAAGGTTTGGCCAGTGTAA
TCATATAAGGCCATCCTGACATTGTTTCTGTGTTTCACAGTTCAGATTTTTATTTACATTAGAA
CCACATTGCTCCTAGGAGAACATTACCTTTAGGGGACTAATTTTCCATGGAGAACTATTTCAGC
ATTTTGCGGGCTGCTTAGACCCCAAGTTAGATATGCACACCGAGCCAGATGAAGCTACACAAAT
GTTGTGTTTAAATGCATTTTGTACAGTGACTTCAGAGTATCTCACACGACGTGGGTGGAAACTG
GCTGGGGAGAAAATGATGCTTGGTCGCCTTTTCCTCCAGCCATGGTTAAGTGGTCCTAGGGGTA
GCAGAGGGAAGGGAGGATTTTGTGCAGTTGAGATTTGCTTTTCCATCCTTGTCTCCTGAATGTC
TAAAATCTCTACATCTTTCTGAAGTTTAACAACTGTCTCTAGAGGTTTGCCAGGCGACAGCTCA
AAGCTTTGCAGAATCTTAGATCTGGAATTAAAGAATTCAAGTCCAAATTGTGAGAACCAGATTT
TACTCAACGGAAAGCTTTTTCTAAGGAATCTGAGTTGTTCACTGGTGGACAGTGAACGCTCCTT
GTTAATAGAATGGGCCACGCTCCCTCTCTGGATATTCACCCACGCCTCTTCAGAATAGGTTTTG
TTCTGGCTAGAAGTGCGGTCTAGAAGATGGCTAAACTCTTTGCCAGCTCTCATTTGGAGTTTTA
TTATTGCATAAAATCTTCGCTCACTCTGCAAATCTATATCTGCCACCTTCGGCATCAGGTGGTG
CAGGGGCACTTCTAAGTGGGCTCTTTTTGTTACAGCACAACTCCCAGACAGTCCTGTGGGTCTT
TGGATTCGTCAGCGTTCCAGCAAACTAGCCCTGCTTAGAAGTTAGCACAAGACGGCAGAATGCA
GGACTCCGTAGGCAAAATCACAACCTTGCCATTAAAAAAAATTTTTTTACATA

hide sequence

RefSeq Acc Id:

XM_007981905 ⟹ XP_007980096

Type:

CODING

Position:

Green Monkey Assembly	Chr	Position (strand)	Source
ChlSab1.1	21	35,934,829 - 36,132,041 (+)	NCBI
Vero_WHO_p1.0	NW_023666042	68,454,107 - 68,649,168 (-)	NCBI

Sequence:

show sequence

TTCTTGTGCAGGAAGAGCACTGAGGAATATTATTATCGTTCAAGCAGCTGACCTGATAAAGGAC
AGAGTGAACCTCAAGGGGTTTTACAGTTTGAATCCTGTTCTGAAGTTAGGGTATGGAATTTCCA
GCCCCAAGTGTGGATGGGCTCCTGAGACAGTCTCTGCTCTGCTTCCTCTGGGACATGATATTTT
GCAGCAGGAGGAGCTGCGTCGGGTCAGAACTGGTAGACTGGCTTCTAGAACACTGTCCTTTTGT
CCAGTGCAGATCTATGGCCATAGGAGTCTGGCAACTCCTACTGGACATGGGAATTATGTTATCA
GTGGACCAGCATCTATACTTTCAAGATACTTATGTTTTCTACCAGTTTTCCTCTGATGAATGTA
GCTACTTGTACTGTGAATTTGAAAGAGAAGAAGAATGGCAAAATGGTGTCAAGCTTTTACTGCA
ACTTGTGCCTCTCATTCCTGCTAGAGCTGGCATCTGTGAGCTGTCTCATCAGAAAATTGAAGAC
TCTGAAGAAAGCAGTGATGAAATTCTTGCGCGTCTAACATCTGCGGTGCAGAGAGAGCTAGCAG
CTGTGATTGCTTTGAAAGCAAGGAAGTCTGCAATTGAACAAGATGAAGAAAACAATGACAAACA
TGTAGCTGTAACAGAAGCCGAAAGTGTTCCAGATTCTCAGGCAGGGGTGATGTGCAAGCTTCAA
GAAAGAGATGAAATCGGACGAATCGAACTAGTTCAGAAGCTGGCAAGAGAAAACTATCAGTTTT
TGCAGACGGACAAAAAAGAACAGGAGAAGTCTGAACACCAAGATGATGAAGTGACGACTGTTCA
GGTTAAAGAGCAAGACCAGAGCGTCCTGGTGCTGAAGAAAGTGCAGTGCTGTGGCCCAGCCCCC
ACAGCTGGGAGTGCGGAGAGCCATTGGAGATATGTGGTGGTGTCCGGGACCCCGGAGAAGATTT
TGGAGCACCTTTTGAATGACTTGCACCTGGAAGAAGTCCAGGACAAAGAAACAGAGACCCTCCT
GGATGACTTCCTTCTCACGTACACTGTCTTCATGACAACTGATGACTTGTGCCAGGCTCTGTTA
AGGCACTATTCCGCTAAGAAGTATCAAGGCAAAGAGGAAAACTCAGATGTTCCGCGTAGGAAAC
GTAAAGTCTTGCATCTTGTTTCCCAGTGGATTGCTCTGTACAAAGACTGGTTACATGAAGATGA
ACATTCAAAAATGTTTTTAAAGACCATATATAGGAATGTACTGGATGATGTTTATGAATATCCA
ATACTTGAAAAAGAATTGAAAGAATTTCAAAAGATACTTGGAATGCACCGTCGTCACACTGTGG
ATGAATATTCACCACAAAAAAAGAATAAAGCCCTTTTCCACCAATTCAGTCTTAAGGAGAACTG
GCTCCAGCATAGAGGAACTGTGACTGAAACAGAGGAAATTTTCTGCCACGTGTATATAACAGAG
CACTCCTATGTCAGTGTGAAGGCAAAAGTTTCCAGTACAGCCCAAGAGATCCTAAAATTCGTCG
CAGAAAAGATCCAGTATGCTGAAGAGGATCTGGCTCTGGTGGCCATCACATTCTCTGGAGGAAA
GCATGAACTTCAGCCGAATGACTTAGTCATCTCCAAATCCCTCGAGGCATCTGGTCGGATATAT
GTCTATCGGAAAGACCTGGCGGACACTTTGAACCCGTTTGCAGAAAATGAGGAATCACAGCAAA
GGTCGATGAGGATTTTGGGAATGAACACTTGGGATCTTGCTCTGGAATTAATGAATTTTGATTG
GAGTCTATTCAATTCAATTCACGAGCAAGAGCTGATCTACTTCACATTCAGCAGACAGGGAAGT
GGGGAACACACTGCAAACCTCAGCCTTCTGCTCCAGAGATGCAATGAGGTCCAGCTCTGGGTGG
CCACGGAGATTCTGCTCTGCAGCCAGCTGGGCAAGCGAGTGCAGCTGGTGAAAAAATTCATCAA
AATTGCGGCTCACTGCAAAGCCCAGAGAAACCTGAATTCTTTCTTTGCCATCGTGATGGGTCTC
AACACTGCTTCTGTCAGTCGACTGTCACAGACCTGGGAGAAAATCCCTGGGAAGTTTAAGAAAC
TTTTCTCTGAACTTGAAAGTTTAACAGATCCTTCCCTAAATCACAAAGCCTACAGAGATGCATT
CAAAAAGATGAAGCCACCAAAAATCCCTTTCATGCCCTTATTGCTTAAAGATGTAACATTTATT
CATGAAGGAAATAAAACGTTTTTGGATAATCTTGTCAATTTTGAAAAGCTGCATATGATCGCAG
ACACTGTCCGAACCCTGAGACACTGCAGGACTAACCAGTTTGGTGACCTGTGTCCAAAAGAGCA
TCAAGAGTTAAAGTCCTATGTTAATCACCTATATGTCATTGACAGCCAGCAGGCCCTGTTCGAG
CTCTCACACAGGATCGAGCCTCGGGTGTGAGCCCCACTGCCTCACCTCCCCTGTGTCTGCAGCA
CTTTGAGCTACGGGAATGTCTATGCCAAGCACGTTGCTTTCCTGTGAGAAAAGAAGTTGCTGAG
TTTTATCAGTATAACCCAAGACATTCACAGGAAAGCCAGCCAAAGCGTGTTCAGGAAGTGATGT
CAGCCACCAGAGAGGGGGAGAGGCCTCTCCATGCTACTCTCTAGACAAGAAGGCAGAAGGAGAG
TCAGAAGCATTCTTGAGATGGAGAAGGCTGGTTTCTTACGATCACATTGTTGATCCAGTCCAGT
TTTCAGTATGAGATGTGCCAGCATCAAGACAAGACAACGACATCTTGACATGCAATGACCGAAT
ATTTCATTAAGAGCATGCATGGAACAGGAAGGAGTTTTACTTTGCCTAGTTTTAGATTACTATC
CATAAGCTGTCAAAGAAGTCATTCTTTTGAACACCTGATGACAGAGACAGCATCCCTAGATCTC
CAGGGAGGAGAGGTTTCTGTTGATACAACGTATGATATCACCAAAAGCCACTTGTGTCTAGGGA
GTTAGTGAGGACTGTAGCTAGCATTCATGCTCTGCTGGGCAGATGAACAATGTCAAGGTGTGCA
TCACTTTGCACCACAATCAACTATTGACACATGCTTGCAAGTGAAATTAGTTTCTGTACAACTG
ATTTGCAGCTATAGGCAAGGTAGATGAAGTTGCTTTGCCAGTAAGGAAAAATAGTAATCTTCAA
GAGATTGACTCATTGTTTAATTCCTGGGGATTTTCTTCACACTTGTAAGCAGGCTCTTATCTTT
TATTGGACATAATATGATTTTGAAAAAGCACAGTGCCTGACACATTGTAGACACTCACTAACTG
CTTACTGAGGTGACAGAGTCACAAAAGTCTGCATTCTTGTGCCTGATGATGCATTTTGCATACC
TCATACAGGCTCCTTGCCCACACTATGGAATGACAGCAGCCAGCACAGGGAGGTTAAGTGACAT
TTAATGAGTGAAGCACTTAGCATTCTCTAGGTAATAAGATAGCGGTAATTACCAGTGTTTTGGC
AAATGAAAAATACCCTGAAATAGCCAAGTGTCTGATTGATGTTGGTGACTTAGAAGTCCTATAG
TCCACCTACCAGCCAAAGCAGGGAGCCTTTCTATAATTTGCCTTTTTTTTCCCCAAAATCTGAG
TCTTCTGAAATCTTTTTTTATTCCCATTTTTACCAATTGAGGCTCCTTCAGCAAATAAGACCTC
TTGATATTTTCAAGGACTGGGTAGAGGATTTCTTTCAACCTTCACATGAACAAAACAGCCTATG
GGTCAAAATAATGAAAGCCACCCCTGCCTGCTAGATACTTGTCACCTTGCTAAAATGCAAGGGC
CTGGTCCATTCATTTTCCAAATGCAGGAGTCTTGGTGCATTTCTCACTCTTCCTGCCTGTTCAT
CTCTTTCATGCCCACACAGACCTGTTTCCTTTTTGTCTCATCAACACCTCATTCATCCTCATTA
ATGAGGCATGTCCAATGCTTTTTGACATCTTTATAGCAGTGCTGTTTCCTGGGCTCAGGAACCA
CACTGAGCGTGAGATACTGCTGGAAGGAACCATGTGGAGAGAAGGTTTGAGAGGACTTTGAGAG
AGACTTAGTTCGGCCCAGCATGTAAAACTTCAGTCCTGAACATTTACGGGGTTTTATAGACGGG
CATCCTCCAGGGCTGGTCCCTTCAGAGAAATGCTGCATGCTGCTGGTCATGGAATGTGGCCCAC
AGGAGGACACCAGAGCCATGAGAACCGGACAGCAGACTTCCCTCACAGCTGGGCTGAGCAAACC
CTCCAAAGCCCTCCTCACACAGTTACTAGCGATAGCATGGGCTTACAGCACAAGCACGTGTGCT
CACCTTTTTCCCATGCACTGGACTAAGGTTTGGCCAGTGTAATCATATAAGGCCATCCTGACAT
TGTTTCTGTGTTTCACAGTTCAGATTTTTATTTACATTAGAACCACATTGCTCCTAGGAGAACA
TTACCTTTAGGGGACTAATTTTCCATGGAGAACTATTTCAGCATTTTGCGGGCTGCTTAGACCC
CAAGTTAGATATGCACACCGAGCCAGATGAAGCTACACAAATGTTGTGTTTAAATGCATTTTGT
ACAGTGACTTCAGAGTATCTCACACGACGTGGGTGGAAACTGGCTGGGGAGAAAATGATGCTTG
GTCGCCTTTTCCTCCAGCCATGGTTAAGTGGTCCTAGGGGTAGCAGAGGGAAGGGAGGATTTTG
TGCAGTTGAGATTTGCTTTTCCATCCTTGTCTCCTGAATGTCTAAAATCTCTACATCTTTCTGA
AGTTTAACAACTGTCTCTAGAGGTTTGCCAGGCGACAGCTCAAAGCTTTGCAGAATCTTAGATC
TGGAATTAAAGAATTCAAGTCCAAATTGTGAGAACCAGATTTTACTCAACGGAAAGCTTTTTCT
AAGGAATCTGAGTTGTTCACTGGTGGACAGTGAACGCTCCTTGTTAATAGAATGGGCCACGCTC
CCTCTCTGGATATTCACCCACGCCTCTTCAGAATAGGTTTTGTTCTGGCTAGAAGTGCGGTCTA
GAAGATGGCTAAACTCTTTGCCAGCTCTCATTTGGAGTTTTATTATTGCATAAAATCTTCGCTC
ACTCTGCAAATCTATATCTGCCACCTTCGGCATCAGGTGGTGCAGGGGCACTTCTAAGTGGGCT
CTTTTTGTTACAGCACAACTCCCAGACAGTCCTGTGGGTCTTTGGATTCGTCAGCGTTCCAGCA
AACTAGCCCTGCTTAGAAGTTAGCACAAGACGGCAGAATGCAGGACTCCGTAGGCAAAATCACA
ACCTTGCCATTAAAAAAAATTTTTTTACATA

hide sequence

RefSeq Acc Id:

XM_038004733 ⟹ XP_037860661

Type:

CODING

Position:

Green Monkey Assembly	Chr	Position (strand)	Source
Vero_WHO_p1.0	NW_023666042	68,454,107 - 68,631,935 (-)	NCBI

RefSeq Acc Id:

XM_038004734 ⟹ XP_037860662

Type:

CODING

Position:

Green Monkey Assembly	Chr	Position (strand)	Source
Vero_WHO_p1.0	NW_023666042	68,454,107 - 68,635,093 (-)	NCBI

Protein Sequences


Protein RefSeqs	XP_007980095	(Get FASTA)	NCBI Sequence Viewer
	XP_007980096	(Get FASTA)	NCBI Sequence Viewer
	XP_037860661	(Get FASTA)	NCBI Sequence Viewer
	XP_037860662	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSCSAP00000010043.1

RefSeq Acc Id:	XP_007980095 ⟸ XM_007981904
- Peptide Label:	isoform X1

RefSeq Acc Id:	XP_007980096 ⟸ XM_007981905
- Peptide Label:	isoform X2

Ensembl Acc Id:

ENSCSAP00000010043 ⟸ ENSCSAT00000011990

RefSeq Acc Id:	XP_037860662 ⟸ XM_038004734
- Peptide Label:	isoform X3

RefSeq Acc Id:	XP_037860661 ⟸ XM_038004733
- Peptide Label:	isoform X3

Additional Information

External Database Links

Database	Acc Id	Source(s)
Ensembl Genes	ENSCSAG00000013898	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSCSAT00000011990.1	UniProtKB/TrEMBL
Gene3D-CATH	1.10.10.10	UniProtKB/TrEMBL
	1.10.840.10	UniProtKB/TrEMBL
	Phosphatidylinositol 3-kinase Catalytic Subunit, Chain A, domain 1	UniProtKB/TrEMBL
	Son of sevenless (SoS) protein Chain: S domain 1	UniProtKB/TrEMBL
InterPro	Ras-like_GEF	UniProtKB/TrEMBL
	Ras-like_Gua-exchang_fac_N	UniProtKB/TrEMBL
	Ras_G-nucl-exch_fac_CS	UniProtKB/TrEMBL
	Ras_GEF_dom_sf	UniProtKB/TrEMBL
	RASGEF_cat_dom	UniProtKB/TrEMBL
	RASGEF_cat_dom_sf	UniProtKB/TrEMBL
	Ubiquitin-like_domsf	UniProtKB/TrEMBL
	WH-like_DNA-bd_sf	UniProtKB/TrEMBL
	WH_DNA-bd_sf	UniProtKB/TrEMBL
NCBI Gene	RAPGEF5	ENTREZGENE
PANTHER	PTHR23113	UniProtKB/TrEMBL
	RAP GUANINE NUCLEOTIDE EXCHANGE FACTOR 5	UniProtKB/TrEMBL
Pfam	RasGEF	UniProtKB/TrEMBL
	RasGEF_N	UniProtKB/TrEMBL
PROSITE	RASGEF	UniProtKB/TrEMBL
	RASGEF_CAT	UniProtKB/TrEMBL
	RASGEF_NTER	UniProtKB/TrEMBL
SMART	RasGEF	UniProtKB/TrEMBL
	RasGEFN	UniProtKB/TrEMBL
Superfamily-SCOP	SSF46785	UniProtKB/TrEMBL
	SSF48366	UniProtKB/TrEMBL
	SSF54236	UniProtKB/TrEMBL
UniProt	A0A0D9RN54_CHLSB	UniProtKB/TrEMBL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD

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Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD