Cobl (cordon-bleu WH2 repeat) - Rat Genome Database

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Gene: Cobl (cordon-bleu WH2 repeat) Mus musculus
Analyze
Symbol: Cobl
Name: cordon-bleu WH2 repeat
RGD ID: 1323756
MGI Page MGI
Description: Enables actin monomer binding activity. Involved in several processes, including actin filament organization; embryonic pattern specification; and positive regulation of cell projection organization. Acts upstream of or within actin cytoskeleton organization and neural tube closure. Located in several cellular components, including growth cone; ruffle; and terminal web. Colocalizes with actin filament. Is expressed in several structures, including central nervous system; chordamesoderm; embryo mesenchyme; gut; and nose. Orthologous to human COBL (cordon-bleu WH2 repeat protein).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: 4732460E13; C530045F18Rik; cordon-bleu protein; mKIAA0633; protein cordon-bleu
RGD Orthologs
Human
Rat
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391112,186,676 - 12,415,022 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1112,186,608 - 12,414,960 (-)EnsemblGRCm39 Ensembl
GRCm381112,236,676 - 12,465,022 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1112,236,608 - 12,464,960 (-)EnsemblGRCm38mm10GRCm38
MGSCv371112,136,679 - 12,364,963 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361112,136,681 - 12,364,803 (-)NCBIMGSCv36mm8
Celera1112,678,618 - 12,909,422 (-)NCBICelera
Cytogenetic Map11A1NCBI
cM Map117.3NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(+)-schisandrin B  (ISO)
(1->4)-beta-D-glucan  (EXP)
1,2-dimethylhydrazine  (EXP)
17beta-estradiol  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,4-dibromophenyl 2,4,5-tribromophenyl ether  (EXP)
3-chloropropane-1,2-diol  (ISO)
4,4'-sulfonyldiphenol  (EXP,ISO)
4-hydroxyphenyl retinamide  (EXP)
aflatoxin B1  (EXP,ISO)
belinostat  (ISO)
benzo[a]pyrene  (EXP,ISO)
benzo[a]pyrene diol epoxide I  (ISO)
benzo[b]fluoranthene  (EXP)
bisphenol A  (EXP,ISO)
caffeine  (ISO)
carbamazepine  (ISO)
carbon nanotube  (EXP)
CGP 52608  (ISO)
chlordecone  (EXP)
chromium(6+)  (EXP)
chrysene  (EXP)
cisplatin  (ISO)
cobalt dichloride  (ISO)
copper(II) sulfate  (EXP,ISO)
coumarin  (ISO)
coumestrol  (ISO)
cyclosporin A  (ISO)
diuron  (ISO)
dorsomorphin  (ISO)
doxorubicin  (ISO)
endosulfan  (ISO)
entinostat  (ISO)
ethanol  (EXP)
etoposide  (EXP)
fenfluramine  (ISO)
folic acid  (EXP)
FR900359  (ISO)
fulvestrant  (ISO)
gentamycin  (ISO)
glyphosate  (ISO)
inulin  (EXP)
lipopolysaccharide  (EXP)
methylmercury chloride  (ISO)
mitomycin C  (EXP)
N-nitrosodiethylamine  (EXP)
nickel atom  (ISO)
O-methyleugenol  (ISO)
p-toluidine  (ISO)
panobinostat  (ISO)
paracetamol  (EXP,ISO)
perfluorooctane-1-sulfonic acid  (EXP)
phenobarbital  (EXP)
pirinixic acid  (EXP)
propanal  (ISO)
propiconazole  (EXP)
resveratrol  (ISO)
SB 431542  (ISO)
sodium arsenite  (EXP,ISO)
Soman  (ISO)
spermine  (EXP)
sunitinib  (ISO)
testosterone  (ISO)
tetrachloromethane  (EXP,ISO)
tetraphene  (EXP)
thioacetamide  (ISO)
thiram  (ISO)
trichostatin A  (ISO)
triclosan  (ISO)
triphenyl phosphate  (ISO)
valproic acid  (ISO)
vinclozolin  (EXP)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
actin filament  (IBA,IDA)
axon  (IDA)
axonal growth cone  (IBA,IDA)
cell cortex  (IDA,ISO)
dendrite  (IDA)
dendritic growth cone  (IBA,IDA)
membrane  (IDA)
neuronal cell body  (IBA,IDA)
perinuclear region of cytoplasm  (IBA,IDA)
plasma membrane  (IBA,IEA,ISO)
ruffle  (IBA,IDA)
terminal web  (IBA,IDA)

Molecular Function

Phenotype Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. MGDs mouse GO annotations MGD data from the GO Consortium
2. MGD IEA MGD IEA
3. Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries. Okazaki N, etal., DNA Res 2003 Feb 28;10(1):35-48.
4. Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Okazaki Y, etal., Nature. 2002 Dec 5;420(6915):563-73.
5. Mouse MP Annotation Import Pipeline RGD automated import pipeline
6. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
7. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
8. Database resources of the National Center for Biotechnology Information. Wheeler DL, etal., Nucleic Acids Res 2001 Jan 1;29(1):11-6.
Additional References at PubMed
PMID:7586755   PMID:8889548   PMID:10349636   PMID:10395797   PMID:11042159   PMID:11076861   PMID:11210191   PMID:11217851   PMID:12477932   PMID:12520002   PMID:12904583   PMID:14512015  
PMID:14610273   PMID:15231714   PMID:15345747   PMID:15489334   PMID:16141072   PMID:16141073   PMID:17229766   PMID:17956734   PMID:17967808   PMID:18799693   PMID:19174477   PMID:21267068  
PMID:21677750   PMID:21725280   PMID:21873635   PMID:22114352   PMID:23223303   PMID:25031432   PMID:26334624   PMID:27464680   PMID:28973166   PMID:29689199   PMID:29891944   PMID:30157434  
PMID:32560809   PMID:32636403   PMID:33230847   PMID:33500348   PMID:34264190   PMID:34898601   PMID:35874829   PMID:36108632  


Genomics

Comparative Map Data
Cobl
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391112,186,676 - 12,415,022 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1112,186,608 - 12,414,960 (-)EnsemblGRCm39 Ensembl
GRCm381112,236,676 - 12,465,022 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1112,236,608 - 12,464,960 (-)EnsemblGRCm38mm10GRCm38
MGSCv371112,136,679 - 12,364,963 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361112,136,681 - 12,364,803 (-)NCBIMGSCv36mm8
Celera1112,678,618 - 12,909,422 (-)NCBICelera
Cytogenetic Map11A1NCBI
cM Map117.3NCBI
COBL
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38751,016,212 - 51,316,809 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl751,016,212 - 51,316,818 (-)EnsemblGRCh38hg38GRCh38
GRCh37751,083,909 - 51,384,506 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36751,051,404 - 51,351,990 (-)NCBINCBI36Build 36hg18NCBI36
Build 34750,858,118 - 51,158,705NCBI
Celera751,148,737 - 51,449,348 (-)NCBICelera
Cytogenetic Map7p12.1NCBI
HuRef750,933,696 - 51,137,285 (-)NCBIHuRef
CHM1_1751,086,207 - 51,386,564 (-)NCBICHM1_1
T2T-CHM13v2.0751,177,453 - 51,478,069 (-)NCBIT2T-CHM13v2.0
CRA_TCAGchr7v2751,089,893 - 51,390,521 (-)NCBI
Cobl
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81491,041,721 - 91,274,272 (-)NCBIGRCr8
mRatBN7.21486,828,137 - 87,060,682 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1486,828,139 - 87,060,800 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1491,237,296 - 91,483,692 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01492,481,631 - 92,728,031 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01488,949,260 - 89,195,657 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01492,341,949 - 92,497,169 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1492,342,957 - 92,577,936 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01492,142,186 - 92,321,314 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41493,154,637 - 93,309,406 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11492,994,412 - 93,340,571 (-)NCBI
Celera1485,826,388 - 85,975,943 (-)NCBICelera
Cytogenetic Map14q21NCBI
COBL
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2655,888,527 - 56,188,488 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan17104,213,250 - 104,513,211 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0751,652,318 - 51,952,256 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1751,894,468 - 52,114,849 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl751,895,807 - 52,097,841 (-)Ensemblpanpan1.1panPan2
COBL
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1182,206,957 - 2,386,333 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl182,208,260 - 2,459,206 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha182,249,781 - 2,393,765 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0182,317,922 - 2,462,079 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl182,264,613 - 2,514,854 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1182,289,962 - 2,433,564 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0182,286,890 - 2,430,828 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0182,423,375 - 2,567,362 (-)NCBIUU_Cfam_GSD_1.0
Cobl
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405118105,650,726 - 105,902,001 (-)NCBIHiC_Itri_2
SpeTri2.0NW_004936686621,502 - 872,824 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
COBL
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.19136,850,521 - 137,055,249 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.29150,659,325 - 150,667,343 (-)NCBISscrofa10.2Sscrofa10.2susScr3
COBL
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1217,501,647 - 7,803,175 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl217,598,126 - 7,803,177 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366606214,578,093 - 14,882,079 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Cobl
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046247403,332,977 - 3,399,915 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Cobl
7344 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:5622
Count of miRNA genes:891
Interacting mature miRNAs:1187
Transcripts:ENSMUST00000046755, ENSMUST00000109650, ENSMUST00000109651, ENSMUST00000130572, ENSMUST00000136549, ENSMUST00000146067, ENSMUST00000172827, ENSMUST00000172919, ENSMUST00000172956, ENSMUST00000174874
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
39128214Lwq20_mliver weight QTL 20 (mouse)1112268637118022724Mouse
26884446Sklq10_mskull length QTL 10, 10 week (mouse)11325000062890826Mouse
1302171Pgia28_mproteoglycan induced arthritis 28 (mouse)Not determined11890609742906218Mouse
4141047Nilac1_mnicotine induced locomotor activity 1 (mouse)Not determined11901178043011942Mouse
1357720Kidpq1_mkidney weight percentage QTL 1 (mouse)Not determined111226863768500330Mouse
1559002Lmrq4_mLeishmania major resistance QTL 4 (mouse)Not determined111226863769684947Mouse
1357722Vtbt11_mvertebral trabecular bone trait 11 (mouse)Not determined11123880487Mouse
1357851Scfq3_msubcutaneous fat pad weight QTL 3 (mouse)Not determined111226863768500330Mouse
27226762Feml21_mfemur length 21, 16 week (mouse)111175000065990826Mouse
1301765Skull15_mskull morphology 15 (mouse)Not determined11125976374Mouse
1357518Tgyl1_mtriglyceride level 1 (mouse)Not determined11688027733916219Mouse
4142308W6q3_mweight 6 weeks QTL 3 (mouse)Not determined111226863768500330Mouse
1357640Orq2_movulation rate QTL 2 (mouse)Not determined111226863768500330Mouse
4141470Egq4_mearly growth QTL 4 (mouse)Not determined1226863768500330Mouse
13524844Ppiq9_mprepulse inhibition QTL 9 (mouse)11904999735077325Mouse
4142109W10q2_mweight 10 weeks QTL 2 (mouse)Not determined1226863768500330Mouse
1300599Cocrb11_mcocaine related behavior 11 (mouse)Not determined11267035536671472Mouse
1300661Lmr6_mleishmaniasis resistance 6 (mouse)Not determined11125976374Mouse
13208559Wght10_mweight 10 (mouse)11395000088890826Mouse
10412216Eae44_mexperimental allergic encephalomyelitis susceptibility 44 (mouse)Not determined111226863739950840Mouse
13208558Lgth12_mbody length 12 (mouse)11395000094890826Mouse
27095925Pglq5_mpelvic girdle length QTL 5, 5 week (mouse)11325000019750000Mouse
1357437Epfq4_mepididymal fat pad weight QTL 4 (mouse)Not determined111226863768500330Mouse
27226741Metcl5_mmetatarsal-calcaneal length 5, 5 week (mouse)11465000046290827Mouse
26884401Huml4_mhumerus length 4, 10 week (mouse)111155000068490826Mouse
1300990Bits3_mbitterness sensitivity 3 (mouse)Not determined11837212142372260Mouse
27226738Metcl11_mmetatarsal-calcaneal length 11, 10 week (mouse)11885000061390826Mouse
27226735Metcl16_mmetatarsal-calcaneal length 16, 16 week (mouse)11525000035090827Mouse
10044008Hbnr15_mHeligmosomoides bakeri nematode resistance 15 (mouse)Not determined1122705234227232Mouse
27226798Scvln18_msacral vertebrae length 2, 16 week (mouse)11325000060690826Mouse
4141582Lgaq1_mlate growth adjusted QTL 1 (mouse)Not determined1226863768500330Mouse
4141966Tailq1_mtail length QTL 1 (mouse)Not determined1226863768500330Mouse
27095919Pglq10_mpelvic girdle length QTL 10, 10 week (mouse)11325000018450000Mouse
1300768Tshp9_mtooth shape 9 (mouse)Not determined11125976374Mouse
10053676Eae44a_mexperimental allergic encephalomyelitis susceptibility 44a (mouse)Not determined11450789621379532Mouse
27226794Feml9_mfemur length 9, 5 week (mouse)11705000016750000Mouse
27095914Pglq16_mpelvic girdle length QTL 16, 16 week (mouse)11325000018150000Mouse
4142216Lgq1_mlate growth QTL 1 (mouse)Not determined1226863768500330Mouse
27095909Scvln6_msacral vertebrae length 2, 5 week (mouse)11325000044090827Mouse
4141127W3q4_mweight 3 weeks QTL 4 (mouse)Not determined1226863768500330Mouse
1300905Scc6_mcolon tumor susceptibility 6 (mouse)Not determined11688027789019734Mouse
13463479Mchq19_mmean corpuscular hemoglobin QTL 19 (mouse)111095123244951464Mouse
27095904Scvln12_msacral vertebrae length 2, 10 week (mouse)11325000034495048Mouse
13463472Mcvq15_mmean corpuscular volume QTL 15 (mouse)111095123244951464Mouse
26884453Sklq16_mskull length QTL 16, 16 week (mouse)11325000072690826Mouse

Markers in Region
D11Mit2  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381112,318,637 - 12,318,743UniSTSGRCm38
MGSCv371112,218,640 - 12,218,746UniSTSGRCm37
Celera1112,763,346 - 12,763,444UniSTS
Cytogenetic Map11A1UniSTS
cM Map112.4UniSTS
Whitehead Genetic114.4UniSTS
Whitehead_YAC11 UniSTS


Expression

RNA-SEQ Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001282993 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001282994 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001401095 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001401096 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001401097 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001401098 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001401099 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001401100 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_172496 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006514481 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_011243651 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_011243652 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_011243653 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_011243654 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_011243656 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_030245514 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AI844390 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK028833 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK049730 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK122334 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK147366 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK147633 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK158651 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AL669822 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AL713914 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AY308745 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC023264 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC025601 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC060061 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC145116 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC145118 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC150706 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BE947965 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CF534605 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH466574 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CJ108083 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  U26967 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSMUST00000046755   ⟹   ENSMUSP00000045693
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1112,186,676 - 12,414,957 (-)Ensembl
GRCm38.p6 Ensembl1112,236,676 - 12,464,957 (-)Ensembl
Ensembl Acc Id: ENSMUST00000109650   ⟹   ENSMUSP00000105277
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1112,186,676 - 12,414,859 (-)Ensembl
GRCm38.p6 Ensembl1112,236,676 - 12,464,859 (-)Ensembl
Ensembl Acc Id: ENSMUST00000109651   ⟹   ENSMUSP00000105278
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1112,186,678 - 12,414,960 (-)Ensembl
GRCm38.p6 Ensembl1112,236,678 - 12,464,960 (-)Ensembl
Ensembl Acc Id: ENSMUST00000130572
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1112,254,867 - 12,414,752 (-)Ensembl
GRCm38.p6 Ensembl1112,304,867 - 12,464,752 (-)Ensembl
Ensembl Acc Id: ENSMUST00000136549   ⟹   ENSMUSP00000114779
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1112,246,363 - 12,319,640 (-)Ensembl
GRCm38.p6 Ensembl1112,296,363 - 12,369,640 (-)Ensembl
Ensembl Acc Id: ENSMUST00000146067   ⟹   ENSMUSP00000119008
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1112,293,847 - 12,328,278 (-)Ensembl
GRCm38.p6 Ensembl1112,343,847 - 12,378,278 (-)Ensembl
Ensembl Acc Id: ENSMUST00000172827   ⟹   ENSMUSP00000133368
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1112,217,007 - 12,319,692 (-)Ensembl
GRCm38.p6 Ensembl1112,267,007 - 12,369,692 (-)Ensembl
Ensembl Acc Id: ENSMUST00000172919   ⟹   ENSMUSP00000133669
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1112,186,608 - 12,414,804 (-)Ensembl
GRCm38.p6 Ensembl1112,236,608 - 12,464,804 (-)Ensembl
Ensembl Acc Id: ENSMUST00000172956   ⟹   ENSMUSP00000134372
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1112,187,111 - 12,414,800 (-)Ensembl
GRCm38.p6 Ensembl1112,237,111 - 12,464,800 (-)Ensembl
Ensembl Acc Id: ENSMUST00000174874   ⟹   ENSMUSP00000133470
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1112,186,678 - 12,362,144 (-)Ensembl
GRCm38.p6 Ensembl1112,236,678 - 12,412,144 (-)Ensembl
RefSeq Acc Id: NM_001282993   ⟹   NP_001269922
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391112,186,676 - 12,414,939 (-)NCBI
GRCm381112,236,676 - 12,464,960 (-)NCBI
Celera1112,678,618 - 12,909,422 (-)NCBI
Sequence:
RefSeq Acc Id: NM_001282994   ⟹   NP_001269923
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391112,186,676 - 12,362,147 (-)NCBI
GRCm381112,236,676 - 12,412,140 (-)NCBI
Celera1112,678,618 - 12,909,422 (-)NCBI
Sequence:
RefSeq Acc Id: NM_001401095   ⟹   NP_001388024
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391112,186,676 - 12,414,939 (-)NCBI
RefSeq Acc Id: NM_001401096   ⟹   NP_001388025
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391112,186,676 - 12,414,939 (-)NCBI
RefSeq Acc Id: NM_001401097   ⟹   NP_001388026
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391112,186,676 - 12,414,939 (-)NCBI
RefSeq Acc Id: NM_001401098   ⟹   NP_001388027
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391112,246,361 - 12,414,939 (-)NCBI
RefSeq Acc Id: NM_001401099   ⟹   NP_001388028
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391112,246,361 - 12,414,939 (-)NCBI
RefSeq Acc Id: NM_001401100   ⟹   NP_001388029
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391112,246,361 - 12,414,661 (-)NCBI
RefSeq Acc Id: NM_172496   ⟹   NP_766084
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391112,186,676 - 12,414,939 (-)NCBI
GRCm381112,236,676 - 12,464,960 (-)NCBI
MGSCv371112,136,679 - 12,364,963 (-)RGD
Celera1112,678,618 - 12,909,422 (-)RGD
cM Map11 ENTREZGENE
Sequence:
RefSeq Acc Id: XM_006514481   ⟹   XP_006514544
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391112,186,676 - 12,415,007 (-)NCBI
GRCm381112,236,676 - 12,464,960 (-)NCBI
Sequence:
RefSeq Acc Id: XM_011243651   ⟹   XP_011241953
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391112,186,676 - 12,415,007 (-)NCBI
GRCm381112,236,676 - 12,464,995 (-)NCBI
Sequence:
RefSeq Acc Id: XM_011243652   ⟹   XP_011241954
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391112,186,676 - 12,381,060 (-)NCBI
GRCm381112,236,676 - 12,431,065 (-)NCBI
Sequence:
RefSeq Acc Id: XM_011243653   ⟹   XP_011241955
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391112,186,676 - 12,415,007 (-)NCBI
GRCm381112,236,676 - 12,464,991 (-)NCBI
Sequence:
RefSeq Acc Id: XM_011243654   ⟹   XP_011241956
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391112,186,676 - 12,415,007 (-)NCBI
GRCm381112,236,676 - 12,464,960 (-)NCBI
Sequence:
RefSeq Acc Id: XM_011243656   ⟹   XP_011241958
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391112,186,676 - 12,415,007 (-)NCBI
GRCm381112,236,676 - 12,464,960 (-)NCBI
Sequence:
RefSeq Acc Id: XM_030245514   ⟹   XP_030101374
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391112,186,676 - 12,415,022 (-)NCBI
GRCm381112,236,676 - 12,465,022 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs NP_001269922 (Get FASTA)   NCBI Sequence Viewer  
  NP_001269923 (Get FASTA)   NCBI Sequence Viewer  
  NP_001388024 (Get FASTA)   NCBI Sequence Viewer  
  NP_001388025 (Get FASTA)   NCBI Sequence Viewer  
  NP_001388026 (Get FASTA)   NCBI Sequence Viewer  
  NP_001388027 (Get FASTA)   NCBI Sequence Viewer  
  NP_001388028 (Get FASTA)   NCBI Sequence Viewer  
  NP_001388029 (Get FASTA)   NCBI Sequence Viewer  
  NP_766084 (Get FASTA)   NCBI Sequence Viewer  
  XP_006514544 (Get FASTA)   NCBI Sequence Viewer  
  XP_011241953 (Get FASTA)   NCBI Sequence Viewer  
  XP_011241954 (Get FASTA)   NCBI Sequence Viewer  
  XP_011241955 (Get FASTA)   NCBI Sequence Viewer  
  XP_011241956 (Get FASTA)   NCBI Sequence Viewer  
  XP_011241958 (Get FASTA)   NCBI Sequence Viewer  
  XP_030101374 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAA92362 (Get FASTA)   NCBI Sequence Viewer  
  AAH23264 (Get FASTA)   NCBI Sequence Viewer  
  AAH60061 (Get FASTA)   NCBI Sequence Viewer  
  AAI45119 (Get FASTA)   NCBI Sequence Viewer  
  AAI50707 (Get FASTA)   NCBI Sequence Viewer  
  AAP74341 (Get FASTA)   NCBI Sequence Viewer  
  BAC26144 (Get FASTA)   NCBI Sequence Viewer  
  BAC33896 (Get FASTA)   NCBI Sequence Viewer  
  BAC65616 (Get FASTA)   NCBI Sequence Viewer  
  EDL40651 (Get FASTA)   NCBI Sequence Viewer  
  EDL40652 (Get FASTA)   NCBI Sequence Viewer  
  EDL40653 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSMUSP00000045693
  ENSMUSP00000045693.8
  ENSMUSP00000105277
  ENSMUSP00000105277.2
  ENSMUSP00000105278
  ENSMUSP00000105278.3
  ENSMUSP00000114779.2
  ENSMUSP00000119008.2
  ENSMUSP00000133368.2
  ENSMUSP00000133470
  ENSMUSP00000133470.2
  ENSMUSP00000133669
  ENSMUSP00000133669.2
  ENSMUSP00000134372
  ENSMUSP00000134372.2
GenBank Protein Q5NBX1 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: NP_766084   ⟸   NM_172496
- Peptide Label: isoform 1
- UniProtKB: Q8CE81 (UniProtKB/Swiss-Prot),   Q8C7Q0 (UniProtKB/Swiss-Prot),   Q80TV4 (UniProtKB/Swiss-Prot),   Q7TQM9 (UniProtKB/Swiss-Prot),   Q6PAT4 (UniProtKB/Swiss-Prot),   Q60859 (UniProtKB/Swiss-Prot),   Q5NBX2 (UniProtKB/Swiss-Prot),   Q8CIM4 (UniProtKB/Swiss-Prot),   Q5NBX1 (UniProtKB/Swiss-Prot),   B2RWU4 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001269922   ⟸   NM_001282993
- Peptide Label: isoform 2
- UniProtKB: G5E8P4 (UniProtKB/TrEMBL),   B2RWU4 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001269923   ⟸   NM_001282994
- Peptide Label: isoform 3
- UniProtKB: G3UWY3 (UniProtKB/TrEMBL),   B2RWU4 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006514544   ⟸   XM_006514481
- Peptide Label: isoform X2
- UniProtKB: B2RWU4 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_011241955   ⟸   XM_011243653
- Peptide Label: isoform X4
- UniProtKB: B2RWU4 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_011241956   ⟸   XM_011243654
- Peptide Label: isoform X5
- UniProtKB: B2RWU4 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_011241958   ⟸   XM_011243656
- Peptide Label: isoform X7
- UniProtKB: B2RWU4 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_011241953   ⟸   XM_011243651
- Peptide Label: isoform X1
- UniProtKB: B2RWU4 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_011241954   ⟸   XM_011243652
- Peptide Label: isoform X3
- UniProtKB: B2RWU4 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_030101374   ⟸   XM_030245514
- Peptide Label: isoform X9
- UniProtKB: B2RWU4 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSMUSP00000045693   ⟸   ENSMUST00000046755
Ensembl Acc Id: ENSMUSP00000133368   ⟸   ENSMUST00000172827
Ensembl Acc Id: ENSMUSP00000133669   ⟸   ENSMUST00000172919
Ensembl Acc Id: ENSMUSP00000134372   ⟸   ENSMUST00000172956
Ensembl Acc Id: ENSMUSP00000119008   ⟸   ENSMUST00000146067
Ensembl Acc Id: ENSMUSP00000133470   ⟸   ENSMUST00000174874
Ensembl Acc Id: ENSMUSP00000105277   ⟸   ENSMUST00000109650
Ensembl Acc Id: ENSMUSP00000105278   ⟸   ENSMUST00000109651
Ensembl Acc Id: ENSMUSP00000114779   ⟸   ENSMUST00000136549
RefSeq Acc Id: NP_001388026   ⟸   NM_001401097
- Peptide Label: isoform 6
RefSeq Acc Id: NP_001388024   ⟸   NM_001401095
- Peptide Label: isoform 4
RefSeq Acc Id: NP_001388025   ⟸   NM_001401096
- Peptide Label: isoform 5
RefSeq Acc Id: NP_001388028   ⟸   NM_001401099
- Peptide Label: isoform 8
RefSeq Acc Id: NP_001388027   ⟸   NM_001401098
- Peptide Label: isoform 7
RefSeq Acc Id: NP_001388029   ⟸   NM_001401100
- Peptide Label: isoform 9
Protein Domains
Cordon-bleu ubiquitin-like   WH2

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q5NBX1-F1-model_v2 AlphaFold Q5NBX1 1-1337 view protein structure

Promoters
RGD ID:8673986
Promoter ID:EPDNEW_M15024
Type:multiple initiation site
Name:Cobl_3
Description:Mus musculus cordon-bleu WH2 repeat , transcript variant 1, mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_M15026  EPDNEW_M15027  
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm381112,295,601 - 12,295,661EPDNEW
RGD ID:6820638
Promoter ID:MM_KWN:6476
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:ES_Cell
Transcripts:ENSMUST00000046755,   ENSMUST00000093315,   ENSMUST00000093316,   ENSMUST00000093317,   ENSMUST00000109649,   ENSMUST00000109650,   NM_172496,   UC007IBE.1,   UC007IBF.1
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv361112,365,301 - 12,365,801 (-)MPROMDB
RGD ID:8673992
Promoter ID:EPDNEW_M15026
Type:single initiation site
Name:Cobl_2
Description:Mus musculus cordon-bleu WH2 repeat , transcript variant 1, mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_M15024  EPDNEW_M15027  
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm381112,412,146 - 12,412,206EPDNEW
RGD ID:8673994
Promoter ID:EPDNEW_M15027
Type:initiation region
Name:Cobl_1
Description:Mus musculus cordon-bleu WH2 repeat , transcript variant 1, mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_M15024  EPDNEW_M15026  
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm381112,464,939 - 12,464,999EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:105056 AgrOrtholog
Ensembl Genes ENSMUSG00000020173 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000046755 ENTREZGENE
  ENSMUST00000046755.14 UniProtKB/Swiss-Prot
  ENSMUST00000109650 ENTREZGENE
  ENSMUST00000109650.8 UniProtKB/Swiss-Prot
  ENSMUST00000109651 ENTREZGENE
  ENSMUST00000109651.9 UniProtKB/TrEMBL
  ENSMUST00000136549.8 UniProtKB/TrEMBL
  ENSMUST00000146067.2 UniProtKB/TrEMBL
  ENSMUST00000172827.8 UniProtKB/TrEMBL
  ENSMUST00000172919 ENTREZGENE
  ENSMUST00000172919.8 UniProtKB/Swiss-Prot
  ENSMUST00000172956 ENTREZGENE
  ENSMUST00000172956.8 UniProtKB/TrEMBL
  ENSMUST00000174874 ENTREZGENE
  ENSMUST00000174874.8 UniProtKB/TrEMBL
InterPro COBL-like UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Cordon-bleu_ubiquitin_domain UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ubiquitin-rel_dom UniProtKB/TrEMBL
  WH2_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:12808 UniProtKB/Swiss-Prot
MGD MGI:105056 ENTREZGENE
NCBI Gene 12808 ENTREZGENE
PANTHER PROTEIN CORDON-BLEU UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PTHR47008 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam Cobl UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  WH2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Cobl PhenoGen
PROSITE WH2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART WH2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF54236 UniProtKB/TrEMBL
UniProt B2RWU4 ENTREZGENE, UniProtKB/TrEMBL
  COBL_MOUSE UniProtKB/Swiss-Prot
  F6RR81_MOUSE UniProtKB/TrEMBL
  F6ZEZ1_MOUSE UniProtKB/TrEMBL
  G3UWP1_MOUSE UniProtKB/TrEMBL
  G3UWY3 ENTREZGENE, UniProtKB/TrEMBL
  G3UZ73_MOUSE UniProtKB/TrEMBL
  G5E8P4 ENTREZGENE, UniProtKB/TrEMBL
  Q5NBX1 ENTREZGENE
  Q5NBX2 ENTREZGENE
  Q60859 ENTREZGENE
  Q6PAT4 ENTREZGENE
  Q7TQM9 ENTREZGENE
  Q80TV4 ENTREZGENE
  Q8C7Q0 ENTREZGENE
  Q8CE81 ENTREZGENE
  Q8CIM4 ENTREZGENE
UniProt Secondary Q5NBX2 UniProtKB/Swiss-Prot
  Q60859 UniProtKB/Swiss-Prot
  Q6PAT4 UniProtKB/Swiss-Prot
  Q7TQM9 UniProtKB/Swiss-Prot
  Q80TV4 UniProtKB/Swiss-Prot
  Q8C7Q0 UniProtKB/Swiss-Prot
  Q8CE81 UniProtKB/Swiss-Prot
  Q8CIM4 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2013-05-14 Cobl  cordon-bleu WH2 repeat    cordon-bleu  Symbol and/or name change 5135510 APPROVED