COBL (cordon-bleu WH2 repeat protein) - Rat Genome Database

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Gene: COBL (cordon-bleu WH2 repeat protein) Pan paniscus
Analyze
Symbol: COBL
Name: cordon-bleu WH2 repeat protein
RGD ID: 11716688
Description: ENCODES a protein that exhibits actin monomer binding (inferred); INVOLVED IN actin cytoskeleton organization (ortholog); neural tube closure (ortholog); ASSOCIATED WITH genetic disease (ortholog); pleomorphic xanthoastrocytoma (ortholog); FOUND IN actin filament (inferred); axon (inferred); axonal growth cone (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: cordon-bleu homolog
RGD Orthologs
Human
Mouse
Rat
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly
Position:
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2655,888,527 - 56,188,488 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan17104,213,250 - 104,513,211 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0751,652,318 - 51,952,256 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1751,894,468 - 52,114,849 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl751,895,807 - 52,097,841 (-)Ensemblpanpan1.1panPan2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:30032202  


Genomics

Comparative Map Data
COBL
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2655,888,527 - 56,188,488 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan17104,213,250 - 104,513,211 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0751,652,318 - 51,952,256 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1751,894,468 - 52,114,849 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl751,895,807 - 52,097,841 (-)Ensemblpanpan1.1panPan2
COBL
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38751,016,212 - 51,316,809 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl751,016,212 - 51,316,818 (-)EnsemblGRCh38hg38GRCh38
GRCh37751,083,909 - 51,384,506 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36751,051,404 - 51,351,990 (-)NCBINCBI36Build 36hg18NCBI36
Build 34750,858,118 - 51,158,705NCBI
Celera751,148,737 - 51,449,348 (-)NCBICelera
Cytogenetic Map7p12.1NCBI
HuRef750,933,696 - 51,137,285 (-)NCBIHuRef
CHM1_1751,086,207 - 51,386,564 (-)NCBICHM1_1
T2T-CHM13v2.0751,177,453 - 51,478,069 (-)NCBIT2T-CHM13v2.0
CRA_TCAGchr7v2751,089,893 - 51,390,521 (-)NCBI
Cobl
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391112,186,676 - 12,415,022 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1112,186,608 - 12,414,960 (-)EnsemblGRCm39 Ensembl
GRCm381112,236,676 - 12,465,022 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1112,236,608 - 12,464,960 (-)EnsemblGRCm38mm10GRCm38
MGSCv371112,136,679 - 12,364,963 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361112,136,681 - 12,364,803 (-)NCBIMGSCv36mm8
Celera1112,678,618 - 12,909,422 (-)NCBICelera
Cytogenetic Map11A1NCBI
cM Map117.3NCBI
Cobl
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81491,041,721 - 91,274,272 (-)NCBIGRCr8
mRatBN7.21486,828,137 - 87,060,682 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1486,828,139 - 87,060,800 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1491,237,296 - 91,483,692 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01492,481,631 - 92,728,031 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01488,949,260 - 89,195,657 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01492,341,949 - 92,497,169 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1492,342,957 - 92,577,936 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01492,142,186 - 92,321,314 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41493,154,637 - 93,309,406 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11492,994,412 - 93,340,571 (-)NCBI
Celera1485,826,388 - 85,975,943 (-)NCBICelera
Cytogenetic Map14q21NCBI
COBL
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1182,206,957 - 2,386,333 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl182,208,260 - 2,459,206 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha182,249,781 - 2,393,765 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0182,317,922 - 2,462,079 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl182,264,613 - 2,514,854 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1182,289,962 - 2,433,564 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0182,286,890 - 2,430,828 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0182,423,375 - 2,567,362 (-)NCBIUU_Cfam_GSD_1.0
Cobl
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405118105,650,726 - 105,902,001 (-)NCBIHiC_Itri_2
SpeTri2.0NW_004936686621,502 - 872,824 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
COBL
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.19136,850,521 - 137,055,249 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.29150,659,325 - 150,667,343 (-)NCBISscrofa10.2Sscrofa10.2susScr3
COBL
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1217,501,647 - 7,803,175 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl217,598,126 - 7,803,177 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366606214,578,093 - 14,882,079 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Cobl
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046247403,332,977 - 3,399,915 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts XM_034964106 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_034964107 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_034964108 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_034964110 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_034964111 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_034964112 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_034964113 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_034964114 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_034964115 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_034964116 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_034964117 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_034964118 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_055115956 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_055115957 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_057302878 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide JARIFH020000006 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSPPAT00000053738   ⟹   ENSPPAP00000030874
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl751,895,807 - 52,096,955 (-)Ensembl
RefSeq Acc Id: ENSPPAT00000053752   ⟹   ENSPPAP00000030888
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl751,900,002 - 52,097,841 (-)Ensembl
RefSeq Acc Id: ENSPPAT00000053761   ⟹   ENSPPAP00000030896
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl751,963,501 - 52,097,841 (-)Ensembl
RefSeq Acc Id: XM_034964106   ⟹   XP_034819997
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2655,888,527 - 56,188,488 (-)NCBI
NHGRI_mPanPan17104,213,250 - 104,513,211 (-)NCBI
Mhudiblu_PPA_v0751,652,318 - 51,952,202 (-)NCBI
RefSeq Acc Id: XM_034964107   ⟹   XP_034819998
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2655,888,527 - 56,188,460 (-)NCBI
NHGRI_mPanPan17104,213,250 - 104,513,183 (-)NCBI
Mhudiblu_PPA_v0751,652,318 - 51,952,204 (-)NCBI
RefSeq Acc Id: XM_034964108   ⟹   XP_034819999
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2655,888,527 - 56,188,463 (-)NCBI
NHGRI_mPanPan17104,213,250 - 104,513,180 (-)NCBI
Mhudiblu_PPA_v0751,652,318 - 51,952,208 (-)NCBI
RefSeq Acc Id: XM_034964110   ⟹   XP_034820001
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2655,888,527 - 56,188,460 (-)NCBI
NHGRI_mPanPan17104,213,250 - 104,513,178 (-)NCBI
Mhudiblu_PPA_v0751,652,318 - 51,952,206 (-)NCBI
RefSeq Acc Id: XM_034964111   ⟹   XP_034820002
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2655,888,527 - 56,188,457 (-)NCBI
NHGRI_mPanPan17104,213,250 - 104,513,174 (-)NCBI
Mhudiblu_PPA_v0751,652,318 - 51,952,202 (-)NCBI
RefSeq Acc Id: XM_034964112   ⟹   XP_034820003
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2655,888,527 - 56,188,460 (-)NCBI
NHGRI_mPanPan17104,213,250 - 104,513,183 (-)NCBI
Mhudiblu_PPA_v0751,652,318 - 51,952,256 (-)NCBI
RefSeq Acc Id: XM_034964113   ⟹   XP_034820004
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2655,888,527 - 56,188,460 (-)NCBI
NHGRI_mPanPan17104,213,250 - 104,513,183 (-)NCBI
Mhudiblu_PPA_v0751,652,318 - 51,952,204 (-)NCBI
RefSeq Acc Id: XM_034964115   ⟹   XP_034820006
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2655,888,527 - 56,188,463 (-)NCBI
NHGRI_mPanPan17104,213,250 - 104,513,180 (-)NCBI
Mhudiblu_PPA_v0751,652,318 - 51,952,208 (-)NCBI
RefSeq Acc Id: XM_034964116   ⟹   XP_034820007
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2655,888,527 - 56,188,460 (-)NCBI
NHGRI_mPanPan17104,213,250 - 104,513,183 (-)NCBI
Mhudiblu_PPA_v0751,652,318 - 51,952,204 (-)NCBI
RefSeq Acc Id: XM_034964117   ⟹   XP_034820008
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2655,934,562 - 56,188,484 (-)NCBI
NHGRI_mPanPan17104,259,294 - 104,513,201 (-)NCBI
Mhudiblu_PPA_v0751,700,563 - 51,952,256 (-)NCBI
RefSeq Acc Id: XM_055115956   ⟹   XP_054971931
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2655,888,527 - 56,188,464 (-)NCBI
NHGRI_mPanPan17104,213,250 - 104,513,181 (-)NCBI
RefSeq Acc Id: XM_055115957   ⟹   XP_054971932
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2655,888,527 - 56,188,464 (-)NCBI
NHGRI_mPanPan17104,213,250 - 104,513,181 (-)NCBI
RefSeq Acc Id: XM_057302878   ⟹   XP_057158861
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2655,888,527 - 56,188,461 (-)NCBI
NHGRI_mPanPan17104,213,250 - 104,513,179 (-)NCBI
Reference Protein Sequences
RefSeq Acc Id: XP_034820003   ⟸   XM_034964112
- Peptide Label: isoform X6
- UniProtKB: A0A2R9BNB1 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_034820006   ⟸   XM_034964115
- Peptide Label: isoform X10
- UniProtKB: A0A2R9BNB1 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_034819999   ⟸   XM_034964108
- Peptide Label: isoform X3
- UniProtKB: A0A2R9BNB1 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_034820001   ⟸   XM_034964110
- Peptide Label: isoform X4
- UniProtKB: A0A2R9BNB1 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_034820007   ⟸   XM_034964116
- Peptide Label: isoform X11
- UniProtKB: A0A2R9BNB1 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_034820004   ⟸   XM_034964113
- Peptide Label: isoform X7
- UniProtKB: A0A2R9BR40 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_034819998   ⟸   XM_034964107
- Peptide Label: isoform X2
- UniProtKB: A0A2R9BNB1 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_034820002   ⟸   XM_034964111
- Peptide Label: isoform X5
- UniProtKB: A0A2R9BR40 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_034819997   ⟸   XM_034964106
- Peptide Label: isoform X1
- UniProtKB: A0A2R9BNB1 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_034820008   ⟸   XM_034964117
- Peptide Label: isoform X13
RefSeq Acc Id: ENSPPAP00000030888   ⟸   ENSPPAT00000053752
RefSeq Acc Id: ENSPPAP00000030896   ⟸   ENSPPAT00000053761
RefSeq Acc Id: ENSPPAP00000030874   ⟸   ENSPPAT00000053738
RefSeq Acc Id: XP_054971932   ⟸   XM_055115957
- Peptide Label: isoform X12
- UniProtKB: A0A2R9BR40 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_054971931   ⟸   XM_055115956
- Peptide Label: isoform X8
- UniProtKB: A0A2R9BR40 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_057158861   ⟸   XM_057302878
- Peptide Label: isoform X9
- UniProtKB: A0A2R9BNB1 (UniProtKB/TrEMBL)
Protein Domains
Cordon-bleu ubiquitin-like   WH2


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSPPAG00000038378 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSPPAT00000053738.1 UniProtKB/TrEMBL
  ENSPPAT00000053752.1 UniProtKB/TrEMBL
  ENSPPAT00000053761.1 UniProtKB/TrEMBL
InterPro COBL-like UniProtKB/TrEMBL
  Cordon-bleu_ubiquitin_domain UniProtKB/TrEMBL
  Ubiquitin-like_domsf UniProtKB/TrEMBL
  WH2_dom UniProtKB/TrEMBL
NCBI Gene COBL ENTREZGENE
PANTHER PROTEIN CORDON-BLEU UniProtKB/TrEMBL
  PTHR47008 UniProtKB/TrEMBL
Pfam Cobl UniProtKB/TrEMBL
  WH2 UniProtKB/TrEMBL
PROSITE WH2 UniProtKB/TrEMBL
SMART WH2 UniProtKB/TrEMBL
Superfamily-SCOP SSF54236 UniProtKB/TrEMBL
UniProt A0A2R9BMM7_PANPA UniProtKB/TrEMBL
  A0A2R9BNB1 ENTREZGENE, UniProtKB/TrEMBL
  A0A2R9BR40 ENTREZGENE, UniProtKB/TrEMBL