Pals2 (protein associated with LIN7 2, MAGUK family member) - Rat Genome Database

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Gene: Pals2 (protein associated with LIN7 2, MAGUK family member) Mus musculus
Analyze
Symbol: Pals2
Name: protein associated with LIN7 2, MAGUK family member
RGD ID: 1323498
MGI Page MGI
Description: Predicted to enable guanylate kinase activity. Predicted to be involved in GDP metabolic process and GMP metabolic process. Located in plasma membrane. Is expressed in heart. Orthologous to human PALS2 (protein associated with LIN7 2, MAGUK p55 family member).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: dlgh4 protein; Fibroblast growth factor-inducible protein 15; MAGUK p55 subfamily member 6; membrane protein, palmitoylated 3 (MAGUK p55 subfamily member 6); membrane protein, palmitoylated 6 (MAGUK p55 subfamily member 6); Mpp6; P; P55; P55t; protein associated with Lin-7 2
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39650,087,206 - 50,176,134 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl650,087,221 - 50,175,919 (+)EnsemblGRCm39 Ensembl
GRCm38650,110,228 - 50,199,154 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl650,110,241 - 50,198,939 (+)EnsemblGRCm38mm10GRCm38
MGSCv37650,060,240 - 50,148,597 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36650,039,963 - 50,128,169 (+)NCBIMGSCv36mm8
Celera650,618,750 - 50,708,304 (+)NCBICelera
Cytogenetic Map6B2.3NCBI
cM Map624.13NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model



  
Object Symbol
Species
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Evidence
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Reference
Notes
Source
Original Reference(s)
Pals2MouseCOVID-19  ISORGD:13234979068941mRNA:decreased expression:peripheral blood mononuclear cell (human)RGDPMID:32228226|REF_RGD_ID:28912744
Object Symbol
Species
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Original Reference(s)
Pals2Mousepleomorphic xanthoastrocytoma  ISORGD:13234978554872ClinVar Annotator: match by term: Pleomorphic xanthoastrocytomaClinVarPMID:28299358

1 to 20 of 93 rows

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
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Source
Original Reference(s)
Pals2Mouse(-)-epigallocatechin 3-gallate multiple interactionsISORGD:13234976480464[potassium chromate(VI) co-treated with epigallocatechin gallate] results in decreased expression of PALS2 mRNACTDPMID:22079256
Pals2Mouse1,2-dimethylhydrazine decreases expressionEXP 64804641,2-Dimethylhydrazine results in decreased expression of PALS2 mRNACTDPMID:22206623
Pals2Mouse17alpha-ethynylestradiol increases expressionISORGD:13118336480464Ethinyl Estradiol results in increased expression of PALS2 mRNACTDPMID:29097150
Pals2Mouse17alpha-ethynylestradiol affects expressionEXP 6480464Ethinyl Estradiol affects the expression of PALS2 mRNACTDPMID:17555576
Pals2Mouse17beta-estradiol multiple interactionsISORGD:13234976480464EGF protein promotes the reaction [Estradiol results in increased expression of PALS2 mRNA]CTDPMID:24758408
Pals2Mouse17beta-estradiol increases expressionEXP 6480464Estradiol results in increased expression of PALS2 mRNACTDPMID:39298647
Pals2Mouse17beta-estradiol increases expressionISORGD:13234976480464Estradiol results in increased expression of PALS2 mRNACTDPMID:23019147|PMID:24758408
Pals2Mouse2,3',4,4',5-Pentachlorobiphenyl increases expressionEXP 64804642,3',4,4',5-pentachlorobiphenyl results in increased expression of PALS2 mRNACTDPMID:31388691
Pals2Mouse2,3,7,8-tetrachlorodibenzodioxine decreases expressionISORGD:13234976480464Tetrachlorodibenzodioxin results in decreased expression of PALS2 mRNACTDPMID:21632981
Pals2Mouse2,3,7,8-tetrachlorodibenzodioxine decreases expressionISORGD:13118336480464Tetrachlorodibenzodioxin results in decreased expression of PALS2 mRNACTDPMID:21215274
Pals2Mouse2,3,7,8-tetrachlorodibenzodioxine multiple interactionsEXP 6480464Tetrachlorodibenzodioxin promotes the reaction [AHR protein binds to PALS2 promoter]CTDPMID:19654925
Pals2Mouse2,3,7,8-tetrachlorodibenzodioxine affects expressionEXP 6480464Tetrachlorodibenzodioxin affects the expression of PALS2 mRNACTDPMID:21570461
Pals2Mouse2,3,7,8-tetrachlorodibenzodioxine increases expressionEXP 6480464Tetrachlorodibenzodioxin results in increased expression of PALS2 mRNACTDPMID:32553695
Pals2Mouse2,4-dibromophenyl 2,4,5-tribromophenyl ether affects expressionEXP 64804642,2',4,4',5-brominated diphenyl ether affects the expression of MPP6 mRNACTDPMID:38648751
Pals2Mouse2-methylcholine affects expressionISORGD:13234976480464beta-methylcholine affects the expression of PALS2 mRNACTDPMID:21179406
Pals2Mouse3,4-methylenedioxymethamphetamine decreases expressionISORGD:13118336480464N-Methyl-3,4-methylenedioxyamphetamine results in decreased expression of PALS2 mRNACTDPMID:30071829
Pals2Mouse3-methylcholanthrene increases expressionEXP 6480464Methylcholanthrene results in increased expression of PALS2 mRNACTDPMID:20713471
Pals2Mouse4,4'-sulfonyldiphenol increases expressionEXP 6480464bisphenol S results in increased expression of PALS2 mRNACTDPMID:39298647
Pals2Mouse4-hydroxyphenyl retinamide increases expressionEXP 6480464Fenretinide results in increased expression of PALS2 mRNACTDPMID:28973697
Pals2Mouse5-aza-2'-deoxycytidine affects expressionISORGD:13234976480464Decitabine affects the expression of PALS2 mRNACTDPMID:23300844

1 to 20 of 93 rows

Biological Process

  
Object Symbol
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Original Reference(s)
Pals2MouseGDP metabolic process involved_inIEAGO:00043852290270 GOCGO_REF:0000108
Pals2MouseGMP metabolic process involved_inIEAGO:00043852290270 GOCGO_REF:0000108

Cellular Component

  
Object Symbol
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Original Reference(s)
Pals2Mousecell-cell junction is_active_inIBAPANTHER:PTN001137125|ZFIN:ZDB-GENE-020712-1|FB:FBgn0261873|MGI:1927339|MGI:1309489|MGI:2386681|UniProtKB:Q96JB8|UniProtKB:O14936|UniProtKB:Q5T2T1|MGI:1328354|UniProtKB:Q8N3R9|FB:FBgn02507852290270 GO_CentralGO_REF:0000033
Pals2Mousemembrane located_inISS 2290270 PMID:10753959MGIPMID:10753959
Pals2Mouseplasma membrane is_active_inIBAPANTHER:PTN001137125|MGI:1927340|UniProtKB:Q13368|UniProtKB:Q5T2T1|MGI:1858257|RGD:62004|MGI:1328354|FB:FBgn0250785|UniProtKB:Q00013|ZFIN:ZDB-GENE-020712-1|MGI:1927339|FB:FBgn0261873|MGI:2386681|MGI:13094892290270 GO_CentralGO_REF:0000033
Pals2Mouseplasma membrane located_inIDA 2290270 PMID:10753959MGIPMID:10753959

Molecular Function

  
Object Symbol
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Original Reference(s)
Pals2MouseGMP kinase activity enablesISS 2290270 PMID:10753959MGIPMID:10753959
Pals2Mouseprotein binding enablesIPIPR:Q8VHG22290270 PMID:18824598MGIPMID:18824598
Pals2Mouseprotein binding enablesIPIUniProtKB:O703182290270 PMID:22025680IntActPMID:22025680
Pals2Mouseprotein binding enablesIPIUniProtKB:Q8R5M82290270 PMID:12826663UniProtPMID:12826663

RGD Manual Annotations


  
Object Symbol
Species
Term
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Original Reference(s)
Pals2Mouseribosome biogenesis pathway   ISORGD:13234979999448 RGD 
Object Symbol
Species
Term
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Reference
Notes
Source
Original Reference(s)
Pals2Mouseabnormal bone structure  IEA 5509061 MGI 
Pals2Mouseabnormal spleen morphology  IEA 5509061 MGI 
Pals2Mouseabnormal stomach morphology  IEA 5509061 MGI 
Pals2Mousedecreased body length  IEA 5509061 MGI 
Pals2Mousedecreased bone mineral content  IEA 5509061 MGI 
Pals2Mousefusion of vertebral arches  IEA 5509061 MGI 
Pals2Mouseincreased total body fat amount  IEA 5509061 MGI 
Pals2Mouseshort tibia  IEA 5509061 MGI 

#
Reference Title
Reference Citation
1. An overview of pre-ribosomal RNA processing in eukaryotes. Henras AK, etal., Wiley Interdiscip Rev RNA. 2015 Mar-Apr;6(2):225-42. doi: 10.1002/wrna.1269. Epub 2014 Oct 27.
2. MGDs mouse GO annotations MGD data from the GO Consortium
3. Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Okazaki Y, etal., Nature. 2002 Dec 5;420(6915):563-73.
4. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
5. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
PMID:8649829   PMID:8889548   PMID:9771715   PMID:10349636   PMID:10753959   PMID:11042159   PMID:11076861   PMID:11217851   PMID:11711860   PMID:12040188   PMID:12351654   PMID:12477932  
PMID:12826663   PMID:14610273   PMID:15782199   PMID:16023581   PMID:16141072   PMID:16141073   PMID:16602821   PMID:16804542   PMID:17938206   PMID:18799693   PMID:18824598   PMID:19075228  
PMID:21267068   PMID:21873635   PMID:22025680   PMID:23306908   PMID:26496610   PMID:26496923   PMID:28378742   PMID:30357511   PMID:30418981   PMID:32325033   PMID:32554809   PMID:38355793  



Pals2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39650,087,206 - 50,176,134 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl650,087,221 - 50,175,919 (+)EnsemblGRCm39 Ensembl
GRCm38650,110,228 - 50,199,154 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl650,110,241 - 50,198,939 (+)EnsemblGRCm38mm10GRCm38
MGSCv37650,060,240 - 50,148,597 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36650,039,963 - 50,128,169 (+)NCBIMGSCv36mm8
Celera650,618,750 - 50,708,304 (+)NCBICelera
Cytogenetic Map6B2.3NCBI
cM Map624.13NCBI
PALS2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38724,573,452 - 24,694,193 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl724,573,268 - 24,694,193 (+)EnsemblGRCh38hg38GRCh38
GRCh37724,613,071 - 24,733,812 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36724,579,610 - 24,694,023 (+)NCBINCBI36Build 36hg18NCBI36
Build 34724,386,324 - 24,500,737NCBI
Celera724,601,884 - 24,715,973 (+)NCBICelera
Cytogenetic Map7p15.3NCBI
HuRef724,544,555 - 24,612,058 (+)NCBIHuRef
CHM1_1724,614,653 - 24,729,063 (+)NCBICHM1_1
T2T-CHM13v2.0724,711,447 - 24,832,205 (+)NCBIT2T-CHM13v2.0
CRA_TCAGchr7v2724,664,991 - 24,779,052 (+)NCBI
Pals2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8480,504,298 - 80,584,951 (+)NCBIGRCr8
mRatBN7.2479,173,488 - 79,257,542 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl479,124,806 - 79,254,140 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx484,389,410 - 84,474,228 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0480,164,949 - 80,249,755 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0478,605,243 - 78,690,062 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0479,846,506 - 79,928,977 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl479,846,521 - 79,926,703 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.04144,471,089 - 144,602,046 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4478,343,494 - 78,424,470 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1478,619,775 - 78,684,435 (+)NCBI
Celera474,082,633 - 74,162,987 (+)NCBICelera
Cytogenetic Map4q24NCBI
Pals2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495541026,610,758 - 26,697,553 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495541026,593,123 - 26,697,553 (+)NCBIChiLan1.0ChiLan1.0
PALS2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2629,430,673 - 29,550,813 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1777,755,407 - 77,873,508 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0725,248,710 - 25,368,829 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1724,853,266 - 24,973,190 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl724,899,798 - 24,967,402 (+)Ensemblpanpan1.1panPan2
PALS2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11438,095,892 - 38,206,730 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1438,095,716 - 38,213,418 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1437,645,606 - 37,756,631 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01438,032,148 - 38,142,984 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1438,031,672 - 38,142,243 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11438,145,746 - 38,256,586 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01437,838,258 - 37,949,172 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01438,180,110 - 38,291,374 (+)NCBIUU_Cfam_GSD_1.0
Pals2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440511882,276,116 - 82,439,288 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049364781,554,293 - 1,647,787 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049364781,554,314 - 1,647,787 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
PALS2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1847,593,049 - 47,710,570 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11847,589,547 - 47,711,433 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21852,549,819 - 52,660,892 (-)NCBISscrofa10.2Sscrofa10.2susScr3
PALS2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12133,681,859 - 33,785,699 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2133,682,127 - 33,737,196 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604270,861,748 - 70,976,955 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Pals2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247395,884,253 - 5,970,960 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247395,880,989 - 5,971,570 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

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Variants in Pals2
4527 total Variants

Predicted Target Of
Summary Value
Count of predictions:658
Count of miRNA genes:363
Interacting mature miRNAs:398
Transcripts:ENSMUST00000036225, ENSMUST00000036236, ENSMUST00000166318, ENSMUST00000167063, ENSMUST00000167319, ENSMUST00000167628, ENSMUST00000171601
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


1 to 10 of 51 rows
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD ID
Symbol
Name
LOD
P Value
Trait
Sub Trait
Chr
Start
Stop
Species
4142271Egq8_mearly growth QTL 8 (mouse)Not determined450382396633110Mouse
1301266Lmr4_mleishmaniasis resistance 4 (mouse)Not determined64209335876093500Mouse
4140989Spqq2_msperm quality QTL 2 (mouse)Not determined1771159851711719Mouse
12910785Pwgrq16_mpost-weaning growth rate QTL 16 (mouse)64380374777788506Mouse
11252142Mom12_mModifier of Min 12 (mouse)63387226167872400Mouse
4140983Srilp_msleep response to influenza, light phase (mouse)Not determined4870349075424693Mouse
12910798Pwgrq5_mpre-weaning growth rate QTL 5 (mouse)64380374777788506Mouse
1300767Aliq4_macute lung injury QTL 4 (mouse)Not determined63627333270273435Mouse
4142259Tabw2_mtally ho associated body weight 2 (mouse)Not determined46912919136400690Mouse
25314319Histh6_mhistamine hypersensitivity 6 (mouse)648696934125336963Mouse

1 to 10 of 51 rows
RH133592  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38650,111,369 - 50,111,579UniSTSGRCm38
MGSCv37650,061,368 - 50,061,578UniSTSGRCm37
Celera650,619,965 - 50,620,175UniSTS
Cytogenetic Map6B2.3UniSTS
16.MMHAP31FLF1.seq  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38650,122,729 - 50,122,887UniSTSGRCm38
MGSCv37650,072,728 - 50,072,886UniSTSGRCm37
Celera650,631,316 - 50,631,474UniSTS
Cytogenetic Map6B2.3UniSTS
Whitehead_YAC6 UniSTS
U42384  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38650,200,414 - 50,200,495UniSTSGRCm38
MGSCv37650,150,413 - 50,150,494UniSTSGRCm37
Celera650,710,133 - 50,710,214UniSTS
Celera648,043,012 - 48,043,093UniSTS
Cytogenetic Map6B2.3UniSTS
Whitehead/MRC_RH6472.33UniSTS
Fin15  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38650,200,283 - 50,200,406UniSTSGRCm38
MGSCv37650,150,282 - 50,150,405UniSTSGRCm37
Celera650,710,002 - 50,710,125UniSTS
Celera648,043,101 - 48,043,224UniSTS
Cytogenetic Map6B2.3UniSTS
cM Map622.5UniSTS






1 to 30 of 38 rows
RefSeq Transcripts NM_001164733 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001164734 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001361247 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001361248 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001411352 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001411353 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001411356 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001411358 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001411359 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001411360 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001411362 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001411366 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001411367 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_019939 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_030255518 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_036152240 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AC153618 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AC153819 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF161181 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF199009 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF199010 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK047380 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK077754 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK144434 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK164549 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK178596 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK184594 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK187690 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK207937 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC042868 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
1 to 30 of 38 rows

Ensembl Acc Id: ENSMUST00000036225   ⟹   ENSMUSP00000038772
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl650,087,363 - 50,175,404 (+)Ensembl
GRCm38.p6 Ensembl650,110,383 - 50,198,424 (+)Ensembl
Ensembl Acc Id: ENSMUST00000036236   ⟹   ENSMUSP00000039314
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl650,087,229 - 50,175,567 (+)Ensembl
GRCm38.p6 Ensembl650,110,249 - 50,198,587 (+)Ensembl
Ensembl Acc Id: ENSMUST00000166318   ⟹   ENSMUSP00000125880
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl650,087,221 - 50,175,578 (+)Ensembl
GRCm38.p6 Ensembl650,110,241 - 50,198,598 (+)Ensembl
Ensembl Acc Id: ENSMUST00000167063
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl650,157,280 - 50,173,538 (+)Ensembl
GRCm38.p6 Ensembl650,180,300 - 50,196,558 (+)Ensembl
Ensembl Acc Id: ENSMUST00000167319
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl650,171,396 - 50,175,307 (+)Ensembl
GRCm38.p6 Ensembl650,194,416 - 50,198,327 (+)Ensembl
Ensembl Acc Id: ENSMUST00000167628   ⟹   ENSMUSP00000129355
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl650,087,840 - 50,157,593 (+)Ensembl
GRCm38.p6 Ensembl650,110,860 - 50,180,613 (+)Ensembl
Ensembl Acc Id: ENSMUST00000171601   ⟹   ENSMUSP00000129004
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl650,087,387 - 50,140,615 (+)Ensembl
GRCm38.p6 Ensembl650,110,407 - 50,163,635 (+)Ensembl
Ensembl Acc Id: ENSMUST00000203415
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl650,087,260 - 50,090,782 (+)Ensembl
GRCm38.p6 Ensembl650,110,280 - 50,113,802 (+)Ensembl
Ensembl Acc Id: ENSMUST00000204545   ⟹   ENSMUSP00000144737
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl650,087,258 - 50,175,919 (+)Ensembl
GRCm38.p6 Ensembl650,110,278 - 50,198,939 (+)Ensembl
RefSeq Acc Id: NM_001164733   ⟹   NP_001158205
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39650,087,220 - 50,176,134 (+)NCBI
GRCm38650,110,241 - 50,198,598 (+)ENTREZGENE
MGSCv37650,060,240 - 50,148,597 (+)RGD
Celera650,618,750 - 50,708,304 (+)RGD
cM Map6 ENTREZGENE
Sequence:
RefSeq Acc Id: NM_001164734   ⟹   NP_001158206
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39650,087,220 - 50,176,134 (+)NCBI
GRCm38650,110,241 - 50,198,598 (+)ENTREZGENE
MGSCv37650,060,240 - 50,148,597 (+)RGD
Celera650,618,750 - 50,708,304 (+)RGD
cM Map6 ENTREZGENE
Sequence:
RefSeq Acc Id: NM_001361247   ⟹   NP_001348176
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39650,087,842 - 50,176,134 (+)NCBI
GRCm38650,110,860 - 50,198,598 (+)NCBI
Sequence:
RefSeq Acc Id: NM_001361248   ⟹   NP_001348177
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39650,087,842 - 50,176,134 (+)NCBI
GRCm38650,110,860 - 50,198,598 (+)NCBI
Sequence:
RefSeq Acc Id: NM_001411352   ⟹   NP_001398281
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39650,087,220 - 50,176,134 (+)NCBI
RefSeq Acc Id: NM_001411353   ⟹   NP_001398282
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39650,087,842 - 50,176,134 (+)NCBI
RefSeq Acc Id: NM_001411356   ⟹   NP_001398285
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39650,087,220 - 50,176,134 (+)NCBI
RefSeq Acc Id: NM_001411358   ⟹   NP_001398287
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39650,087,842 - 50,176,134 (+)NCBI
RefSeq Acc Id: NM_001411359   ⟹   NP_001398288
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39650,087,220 - 50,176,134 (+)NCBI
RefSeq Acc Id: NM_001411360   ⟹   NP_001398289
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39650,087,220 - 50,176,134 (+)NCBI
RefSeq Acc Id: NM_001411362   ⟹   NP_001398291
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39650,087,220 - 50,176,134 (+)NCBI
RefSeq Acc Id: NM_001411366   ⟹   NP_001398295
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39650,087,220 - 50,176,134 (+)NCBI
RefSeq Acc Id: NM_001411367   ⟹   NP_001398296
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39650,087,220 - 50,176,134 (+)NCBI
RefSeq Acc Id: NM_019939   ⟹   NP_064323
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39650,087,220 - 50,176,134 (+)NCBI
GRCm38650,110,241 - 50,198,598 (+)ENTREZGENE
MGSCv37650,060,240 - 50,148,597 (+)RGD
Celera650,618,750 - 50,708,304 (+)RGD
cM Map6 ENTREZGENE
Sequence:
RefSeq Acc Id: XM_030255518   ⟹   XP_030111378
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39650,087,206 - 50,176,134 (+)NCBI
GRCm38650,110,228 - 50,199,154 (+)NCBI
Sequence:
RefSeq Acc Id: XM_036152240   ⟹   XP_036008133
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39650,114,725 - 50,176,134 (+)NCBI
Sequence:
1 to 30 of 40 rows
Protein RefSeqs NP_001158205 (Get FASTA)   NCBI Sequence Viewer  
  NP_001158206 (Get FASTA)   NCBI Sequence Viewer  
  NP_001348176 (Get FASTA)   NCBI Sequence Viewer  
  NP_001348177 (Get FASTA)   NCBI Sequence Viewer  
  NP_001398281 (Get FASTA)   NCBI Sequence Viewer  
  NP_001398282 (Get FASTA)   NCBI Sequence Viewer  
  NP_001398285 (Get FASTA)   NCBI Sequence Viewer  
  NP_001398287 (Get FASTA)   NCBI Sequence Viewer  
  NP_001398288 (Get FASTA)   NCBI Sequence Viewer  
  NP_001398289 (Get FASTA)   NCBI Sequence Viewer  
  NP_001398291 (Get FASTA)   NCBI Sequence Viewer  
  NP_001398295 (Get FASTA)   NCBI Sequence Viewer  
  NP_001398296 (Get FASTA)   NCBI Sequence Viewer  
  NP_064323 (Get FASTA)   NCBI Sequence Viewer  
  XP_030111378 (Get FASTA)   NCBI Sequence Viewer  
  XP_036008133 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAD45009 (Get FASTA)   NCBI Sequence Viewer  
  AAF63790 (Get FASTA)   NCBI Sequence Viewer  
  AAF63791 (Get FASTA)   NCBI Sequence Viewer  
  AAH46421 (Get FASTA)   NCBI Sequence Viewer  
  AAH69908 (Get FASTA)   NCBI Sequence Viewer  
  AAI06141 (Get FASTA)   NCBI Sequence Viewer  
  AAI38667 (Get FASTA)   NCBI Sequence Viewer  
  AAI45364 (Get FASTA)   NCBI Sequence Viewer  
  AAI45365 (Get FASTA)   NCBI Sequence Viewer  
  BAC36993 (Get FASTA)   NCBI Sequence Viewer  
  BAE25887 (Get FASTA)   NCBI Sequence Viewer  
  BAE37835 (Get FASTA)   NCBI Sequence Viewer  
  EDK98615 (Get FASTA)   NCBI Sequence Viewer  
  EDK98616 (Get FASTA)   NCBI Sequence Viewer  
1 to 30 of 40 rows
1 to 5 of 22 rows
1 to 5 of 22 rows
RefSeq Acc Id: NP_064323   ⟸   NM_019939
- Peptide Label: isoform b
- UniProtKB: B9EHZ5 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001158205   ⟸   NM_001164733
- Peptide Label: isoform a
- UniProtKB: Q9JLB1 (UniProtKB/Swiss-Prot),   Q9WV37 (UniProtKB/Swiss-Prot),   Q9JLB0 (UniProtKB/Swiss-Prot),   Q3UN60 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001158206   ⟸   NM_001164734
- Peptide Label: isoform a
- UniProtKB: Q9JLB1 (UniProtKB/Swiss-Prot),   Q9WV37 (UniProtKB/Swiss-Prot),   Q9JLB0 (UniProtKB/Swiss-Prot),   Q3UN60 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_030111378   ⟸   XM_030255518
- Peptide Label: isoform X3
RefSeq Acc Id: NP_001348177   ⟸   NM_001361248
- Peptide Label: isoform a
- UniProtKB: Q9JLB1 (UniProtKB/Swiss-Prot),   Q9JLB0 (UniProtKB/Swiss-Prot),   Q9WV37 (UniProtKB/Swiss-Prot),   Q3UN60 (UniProtKB/TrEMBL)
Guanylate kinase-like   L27   PDZ   SH3

Name Modeler Protein Id AA Range Protein Structure
AF-Q9JLB0-F1-model_v2 AlphaFold Q9JLB0 1-553 view protein structure

RGD ID:6839652
Promoter ID:MM_KWN:45961
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:3T3L1_Day4,   BoneMarrow_0Hour,   BoneMarrow_2Hour,   BoneMarrow_4Hour,   ES_Cell,   Liver
Transcripts:NM_001164733,   NM_001164734,   NM_019939,   UC009BWW.1
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv36650,060,316 - 50,060,937 (+)MPROMDB
RGD ID:6889676
Promoter ID:EPDNEW_M8289
Type:initiation region
Name:Mpp6_1
Description:Mus musculus membrane protein, palmitoylated 6 , transcript variant5, mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_M8290  EPDNEW_M8291  
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38650,110,242 - 50,110,302EPDNEW
RGD ID:6889678
Promoter ID:EPDNEW_M8290
Type:initiation region
Name:Mpp6_2
Description:Mus musculus membrane protein, palmitoylated 6 , transcript variant5, mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_M8289  EPDNEW_M8291  
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38650,110,867 - 50,110,927EPDNEW
RGD ID:6889680
Promoter ID:EPDNEW_M8291
Type:single initiation site
Name:Mpp6_3
Description:Mus musculus membrane protein, palmitoylated 6 , transcript variant5, mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_M8289  EPDNEW_M8290  
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38650,129,358 - 50,129,418EPDNEW


1 to 40 of 62 rows
Database
Acc Id
Source(s)
Ensembl Genes ENSMUSG00000038388 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSMUST00000036225 ENTREZGENE
  ENSMUST00000036225.15 UniProtKB/Swiss-Prot
  ENSMUST00000036236 ENTREZGENE
  ENSMUST00000036236.15 UniProtKB/Swiss-Prot
  ENSMUST00000166318 ENTREZGENE
  ENSMUST00000166318.8 UniProtKB/Swiss-Prot
  ENSMUST00000204545 ENTREZGENE
  ENSMUST00000204545.3 UniProtKB/Swiss-Prot
Gene3D-CATH 2.30.42.10 UniProtKB/Swiss-Prot
  3.40.50.300 UniProtKB/Swiss-Prot
  L27 domain UniProtKB/Swiss-Prot
  SH3 Domains UniProtKB/Swiss-Prot
InterPro GK/Ca_channel_bsu UniProtKB/Swiss-Prot
  Guanylate_kin-like_dom UniProtKB/Swiss-Prot
  Guanylate_kinase_CS UniProtKB/Swiss-Prot
  L27_C UniProtKB/Swiss-Prot
  L27_dom UniProtKB/Swiss-Prot
  L27_dom_sf UniProtKB/Swiss-Prot
  MAGUK UniProtKB/Swiss-Prot
  MPP6_SH3 UniProtKB/Swiss-Prot
  P-loop_NTPase UniProtKB/Swiss-Prot
  PDZ UniProtKB/Swiss-Prot
  PDZ_sf UniProtKB/Swiss-Prot
  SH3-like_dom_sf UniProtKB/Swiss-Prot
  SH3_domain UniProtKB/Swiss-Prot
KEGG Report mmu:56524 UniProtKB/Swiss-Prot
MGD MGI:1927340 ENTREZGENE
NCBI Gene 56524 ENTREZGENE
PANTHER MEMBRANE-ASSOCIATED GUANYLATE KINASE MAGUK UniProtKB/Swiss-Prot
Pfam Guanylate_kin UniProtKB/Swiss-Prot
  L27 UniProtKB/Swiss-Prot
  PDZ UniProtKB/Swiss-Prot
  SH3_2 UniProtKB/Swiss-Prot
PhenoGen Pals2 PhenoGen
PROSITE GUANYLATE_KINASE_1 UniProtKB/Swiss-Prot
  GUANYLATE_KINASE_2 UniProtKB/Swiss-Prot
  L27 UniProtKB/Swiss-Prot
  PDZ UniProtKB/Swiss-Prot
  SH3 UniProtKB/Swiss-Prot
1 to 40 of 62 rows


Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2021-04-19 Pals2  protein associated with LIN7 2, MAGUK family member  Mpp6  membrane protein, palmitoylated 6 (MAGUK p55 subfamily member 6)  Symbol and/or name updated 27372883 PROVISIONAL