Mrto4 (mRNA turnover 4, ribosome maturation factor) - Rat Genome Database

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Gene: Mrto4 (mRNA turnover 4, ribosome maturation factor) Mus musculus
Analyze
Symbol: Mrto4
Name: mRNA turnover 4, ribosome maturation factor
RGD ID: 1323308
MGI Page MGI
Description: Predicted to be involved in nuclear-transcribed mRNA catabolic process; rRNA processing; and ribosomal large subunit biogenesis. Predicted to be located in cytoplasm. Predicted to be part of preribosome, large subunit precursor. Predicted to be active in nucleolus. Is expressed in genitourinary system; liver lobe; pancreas; and submandibular gland primordium. Orthologous to human MRTO4 (MRT4 homolog, ribosome maturation factor).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: 2610012O22Rik; Mg684; mRNA turnover 4, homolog; mRNA turnover protein 4 homolog; Mrt; Mrt4; MRT4, mRNA turnover 4, homolog; muscle protein684; ribosome assembly factor Mrto4
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Related Pseudogenes: Gm15783   Gm18976   Gm3919   Gm8376   Mrto4-ps1  
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm394139,074,751 - 139,079,887 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl4139,074,746 - 139,079,887 (-)EnsemblGRCm39 Ensembl
GRCm384139,347,440 - 139,352,576 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl4139,347,435 - 139,352,576 (-)EnsemblGRCm38mm10GRCm38
MGSCv374138,903,360 - 138,908,213 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv364138,619,521 - 138,624,374 (-)NCBIMGSCv36mm8
Celera4141,134,667 - 141,139,519 (-)NCBICelera
Cytogenetic Map4D3NCBI
cM Map470.65NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(+)-schisandrin B  (ISO)
(-)-alpha-phellandrene  (ISO)
(1->4)-beta-D-glucan  (EXP)
1,2-dimethylhydrazine  (EXP)
17beta-estradiol  (ISO)
2,2',4,4'-Tetrabromodiphenyl ether  (EXP)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2-palmitoylglycerol  (ISO)
6-propyl-2-thiouracil  (ISO)
acrylamide  (ISO)
aflatoxin B1  (ISO)
all-trans-retinoic acid  (ISO)
alpha-phellandrene  (ISO)
amitrole  (ISO)
antirheumatic drug  (ISO)
atrazine  (ISO)
benzo[a]pyrene  (EXP,ISO)
benzo[a]pyrene diol epoxide I  (ISO)
bis(2-ethylhexyl) phthalate  (ISO)
bisphenol A  (EXP,ISO)
cadmium atom  (EXP)
cadmium dichloride  (EXP)
carbon nanotube  (EXP)
chlordecone  (EXP)
chlorpyrifos  (EXP)
chromium(6+)  (EXP)
cobalt dichloride  (ISO)
coumestrol  (ISO)
cyclosporin A  (ISO)
DDE  (ISO)
Dibutyl phosphate  (ISO)
dibutyl phthalate  (EXP,ISO)
dioxygen  (ISO)
endosulfan  (ISO)
ethyl methanesulfonate  (ISO)
flutamide  (ISO)
folic acid  (EXP)
formaldehyde  (ISO)
gentamycin  (ISO)
glafenine  (ISO)
inulin  (EXP)
ivermectin  (ISO)
ketoconazole  (ISO)
methimazole  (ISO)
methyl methanesulfonate  (ISO)
mono(2-ethylhexyl) phthalate  (ISO)
nefazodone  (ISO)
nickel atom  (ISO)
nimesulide  (ISO)
ozone  (EXP)
paraquat  (ISO)
perfluorononanoic acid  (ISO)
perfluorooctane-1-sulfonic acid  (EXP)
perfluorooctanoic acid  (ISO)
phenobarbital  (EXP)
pirinixic acid  (ISO)
pregnenolone 16alpha-carbonitrile  (EXP)
progesterone  (ISO)
resveratrol  (EXP,ISO)
SB 431542  (ISO)
sodium arsenite  (ISO)
sodium dichromate  (ISO)
Soman  (ISO)
sulfadimethoxine  (ISO)
sunitinib  (ISO)
tetrachloromethane  (ISO)
thioacetamide  (ISO)
thiram  (ISO)
trichostatin A  (ISO)
trimellitic anhydride  (EXP)
triptonide  (EXP)
urethane  (ISO)
valproic acid  (ISO)
vinclozolin  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Functional annotation of a full-length mouse cDNA collection. Kawai J, etal., Nature. 2001 Feb 8;409(6821):685-90.
2. Electronic Transfer of Homolog Data MGD and Homologene mouse data transfer
3. MGDs mouse GO annotations MGD data from the GO Consortium
4. Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Okazaki Y, etal., Nature. 2002 Dec 5;420(6915):563-73.
5. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
6. Database resources of the National Center for Biotechnology Information. Wheeler DL, etal., Nucleic Acids Res 2001 Jan 1;29(1):11-6.
Additional References at PubMed
PMID:8889548   PMID:10349636   PMID:10922068   PMID:11042159   PMID:11076861   PMID:12477932   PMID:12904583   PMID:14610273   PMID:15489334   PMID:15782199   PMID:16141072   PMID:16141073  
PMID:18287559   PMID:18799693   PMID:21267068   PMID:21677750   PMID:21873635   PMID:24457600   PMID:26336360   PMID:28378742   PMID:30457570   PMID:32098917   PMID:32325033   PMID:32434143  


Genomics

Comparative Map Data
Mrto4
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm394139,074,751 - 139,079,887 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl4139,074,746 - 139,079,887 (-)EnsemblGRCm39 Ensembl
GRCm384139,347,440 - 139,352,576 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl4139,347,435 - 139,352,576 (-)EnsemblGRCm38mm10GRCm38
MGSCv374138,903,360 - 138,908,213 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv364138,619,521 - 138,624,374 (-)NCBIMGSCv36mm8
Celera4141,134,667 - 141,139,519 (-)NCBICelera
Cytogenetic Map4D3NCBI
cM Map470.65NCBI
MRTO4
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38119,251,805 - 19,260,128 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl119,251,805 - 19,260,128 (+)EnsemblGRCh38hg38GRCh38
GRCh37119,578,299 - 19,586,622 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36119,450,662 - 19,459,209 (+)NCBINCBI36Build 36hg18NCBI36
Build 34119,323,604 - 19,331,064NCBI
Celera117,905,060 - 17,913,606 (+)NCBICelera
Cytogenetic Map1p36.13NCBI
HuRef117,824,619 - 17,833,165 (+)NCBIHuRef
CHM1_1119,687,405 - 19,695,952 (+)NCBICHM1_1
T2T-CHM13v2.0119,075,329 - 19,083,650 (+)NCBIT2T-CHM13v2.0
Mrto4
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr85156,884,985 - 156,891,738 (-)NCBIGRCr8
mRatBN7.25151,601,780 - 151,608,533 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl5151,601,780 - 151,608,287 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx5154,300,433 - 154,307,186 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.05156,074,793 - 156,081,547 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.05156,055,735 - 156,062,489 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.05157,814,142 - 157,820,889 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl5157,815,361 - 157,820,889 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.05161,553,854 - 161,560,601 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.45158,149,143 - 158,154,671 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.15158,159,199 - 158,164,409 (-)NCBI
Celera5149,982,626 - 149,988,154 (-)NCBICelera
Cytogenetic Map5q36NCBI
Mrto4
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495552712,547 - 18,906 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495552712,547 - 18,906 (-)NCBIChiLan1.0ChiLan1.0
MRTO4
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21207,855,187 - 207,863,589 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11206,971,949 - 206,980,338 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0118,210,403 - 18,218,800 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1119,257,147 - 19,265,717 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl119,257,147 - 19,265,038 (+)Ensemblpanpan1.1panPan2
MRTO4
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1279,360,897 - 79,367,038 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl279,360,970 - 79,366,935 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha275,875,788 - 75,881,913 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0279,983,604 - 79,989,727 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl279,983,677 - 79,989,638 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1276,744,427 - 76,750,539 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0277,754,345 - 77,760,465 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0278,825,044 - 78,831,167 (-)NCBIUU_Cfam_GSD_1.0
Mrto4
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440505839,714,526 - 39,721,298 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049364745,539,246 - 5,546,087 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049364745,539,306 - 5,546,085 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
MRTO4
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl677,747,819 - 77,754,864 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1677,747,799 - 77,753,924 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2671,809,896 - 71,816,028 (+)NCBISscrofa10.2Sscrofa10.2susScr3
MRTO4
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.120113,299,433 - 113,306,729 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl20113,299,708 - 113,306,704 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660332,849,826 - 2,857,329 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Mrto4
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247644,400,731 - 4,407,180 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247644,401,005 - 4,406,157 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Mrto4
315 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:1156
Count of miRNA genes:518
Interacting mature miRNAs:618
Transcripts:ENSMUST00000030513, ENSMUST00000102503, ENSMUST00000123968, ENSMUST00000128239, ENSMUST00000131052, ENSMUST00000139749, ENSMUST00000155257
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1301267Bcmd2_mB cell maturation defect 2 (mouse)Not determined4133154678150789451Mouse
4142139Adip12_madiposity 12 (mouse)Not determined4124621281156860686Mouse
10047132Albq19_malbuminuria QTL 19 (mouse)Not determined4112824389146824389Mouse
1301525Lmb1_mlupus in MRL and B6 F2 cross (mouse)Not determined4124264957150676858Mouse
14746982Manh56_mmandible shape 56 (mouse)4117815917151815917Mouse
4141623W6q13_mweight 6 weeks QTL 13 (mouse)Not determined88982069140468203Mouse
12910797Pwgrq4_mpre-weaning growth rate QTL 4 (mouse)4105835310141433838Mouse
25314312Syncl2_msynaptonemal complex length 2 (mouse)465718237146584457Mouse
12910794Pwbwq8_mpost-weaning body weight QTL 8 (mouse)4105835310141433838Mouse
1300743Skull6_mskull morphology 6 (mouse)Not determined4111009051145009280Mouse
1301382Arvm2_mautoimmune renal vasculitis 2 (mouse)Not determined4107791564141791756Mouse
1302149Tlsr2_mthymic lymphoma suppressor region 2 (mouse)Not determined4124264957142230960Mouse
12910813Pwbwq4_mpre-weaning body weight QTL 4 (mouse)4105835310141433838Mouse
1300874Gasa2_mgastritis type A susceptibility locus 2 (mouse)Not determined4133010494156860686Mouse
4141093W3q17_mweight 3 weeks QTL 17 (mouse)Not determined88982069140468203Mouse
27226757Femd1_mfemur midshaft diameter 1, 5 week (mouse)4123993793144326570Mouse
12910808Pwbwq9_mpost-weaning body weight QTL 9 (mouse)4105835310141433838Mouse
1300621Tpnr1_mthermal pain response 1 (mouse)Not determined4125230872156860686Mouse
11567249Elorr3_methanol induced loss of righting response 3 (mouse)43722677156268235Mouse
4142493Femwf13_mfemur work to failure 13 (mouse)Not determined116154678150154782Mouse
1301815Sles2_msystemic lupus erythmatosus suppressor 2 (mouse)Not determined494957579150676858Mouse
1300663Start2_mstartle response 2 (mouse)Not determined4107264957141265153Mouse
1300917Gasa1_mgastritis type A susceptibility locus 1 (mouse)Not determined4124055093142438020Mouse
1300537Ap3q_malcohol preference 3 QTL (mouse)Not determined4134654451156860686Mouse
1301823Bmd7_mbone mineral density 7 (mouse)Not determined488982069151654550Mouse
10412210Cypr6_mcytokine production 6 (mouse)Not determined4120617848154617995Mouse
1302078Sluc21_msusceptibility to lung cancer 21 (mouse)Not determined4117401141151401275Mouse
10045620Heal22_mwound healing/regeneration 22 (mouse)Not determined4125230872156860686Mouse
4142481Gct1_mgranulosa cell tumorigenesis 1 (mouse)Not determined4127784226156860686Mouse
4141065Shali2_msurvival time to hyperoxic acute lung injury 2 (mouse)Not determined124055093141572792Mouse
13503348Bntq18_mbone traits QTL 18 (mouse)4120617848154617995Mouse
13208562Wght7_mweight 7 (mouse)490888237148084457Mouse
1300781Lith8_mlithogenic gene 8 (mouse)Not determined4107264957141265153Mouse
4141184Tb2r1_mTGF-beta2 responsiveness 1 (mouse)Not determined137674005150676858Mouse
1300780Cocrb16_mcocaine related behavior 16 (mouse)Not determined4138943725156860686Mouse
39128212Lwq21_mliver weight QTL 21 (mouse)488982069140468203Mouse
4142077Ignpq2_mIgA nephropathy QTL 2 (mouse)Not determined4133676733156860686Mouse
4141180Ssic1_msusceptibility to small intestinal cancer 1 (mouse)Not determined120674005154674151Mouse
1301584Lrdg2_mlight induced retinal degeneration 2 (mouse)Not determined4129465811151654550Mouse
1302102Bis1_mbeta-carboline-induced seizures 1 (mouse)Not determined4119864433153864536Mouse
10043996Gct5_mgranulosa cell tumorigenesis 5 (mouse)Not determined4127784226156860686Mouse
26884445Sklq7_mskull length QTL 7, 10 week (mouse)468018237150884457Mouse
10043985Stheal12_msoft tissue heal 12 (mouse)Not determined4121342649155342753Mouse
1357534Cinda3_mcytokine induced activation 3 (mouse)Not determined4137617848142289472Mouse
1301982Pltiq1_mphospholipid transfer protein inducibility QTL 1 (mouse)Not determined4124621281156860686Mouse
26884437Sklq13_mskull length QTL 13, 16 week (mouse)457700000155684457Mouse
1300803Sluc6_msusceptibility to lung cancer 6 (mouse)Not determined4120674005154674151Mouse
4141549W10q10_mweight 10 weeks QTL 10 (mouse)Not determined88982069140468203Mouse
4142061Chlq16_mcirculating hormone level QTL 16 (mouse)Not determined4121342649155342753Mouse
1300933Cdcs9_mcytokine deficiency colitis susceptibility 9 (mouse)Not determined4125230872156860686Mouse
1300809Ccrs2_mcorpus callosum hemisphere surface size 2 (mouse)Not determined4107264957141265153Mouse
1300553Athsq1_matherosclerosis susceptibility QTL 1 (mouse)Not determined4137617848151654550Mouse
4141154Nba1_mNew Zealand Black autoimmunity 1 (mouse)Not determined131650724140879275Mouse
1301964Bw8q2_mbody weight at 8 weeks QTL 2 (mouse)Not determined4119864433153864536Mouse
1301452Elsgp1_melevated serum gp70 1 (mouse)Not determined4121342649155342753Mouse
10755520Rbc1_mred blood cell count 1 (mouse)4108477692142477692Mouse
10755521Hct1_mhematocrit 1 (mouse)4108477692142477692Mouse
10755522Hgb1_mhemoglobin 1 (mouse)4108477692142477692Mouse
1301108Scon2_msucrose consumption 2 (mouse)Not determined4134654451156860686Mouse
1300858Tafat_mtally ho associated mesenteric fat pad weight (mouse)Not determined4124621281156860686Mouse
10755531Lymph3_mlymphocyte differential 3 (mouse)4124553483156860686Mouse
15039382Ltgq7_mliver triglyceride QTL 7 (mouse)4105705794139705794Mouse
11533916Mts1_mmammary tumor susceptibility 1 (mouse)4125289325156860686Mouse
15039377Bw45_mbody weight QTL 45 (mouse)4105705794139705794Mouse
1300839Dyscalc2_mdystrophic cardiac calcinosis 2 (mouse)Not determined4111009051145009280Mouse
4141001Tgq17_mtriglyceride QTL 17 (mouse)Not determined112523489146523489Mouse
15039378Adip30_madiposity 30 (mouse)4105705794139705794Mouse
1357800Tgq3_mtriglyceride QTL 3 (mouse)Not determined4107055093141055180Mouse
15039385Mvlq3_mmacrovesicular liver lesion QTL 3 (mouse)4112182386146182386Mouse

Markers in Region
AW742486  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm384139,348,719 - 139,349,756UniSTSGRCm38
MGSCv374138,904,634 - 138,905,671UniSTSGRCm37
Celera4141,135,942 - 141,136,979UniSTS
Cytogenetic Map4D3UniSTS
Whitehead/MRC_RH41819.13UniSTS


Expression

RNA-SEQ Expression


Sequence


Ensembl Acc Id: ENSMUST00000030513   ⟹   ENSMUSP00000030513
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl4139,074,756 - 139,079,609 (-)Ensembl
GRCm38.p6 Ensembl4139,347,445 - 139,352,298 (-)Ensembl
Ensembl Acc Id: ENSMUST00000102503   ⟹   ENSMUSP00000099561
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl4139,074,746 - 139,079,887 (-)Ensembl
GRCm38.p6 Ensembl4139,347,435 - 139,352,576 (-)Ensembl
Ensembl Acc Id: ENSMUST00000123968
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl4139,077,186 - 139,079,621 (-)Ensembl
GRCm38.p6 Ensembl4139,349,875 - 139,352,310 (-)Ensembl
Ensembl Acc Id: ENSMUST00000128239
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl4139,075,473 - 139,076,932 (-)Ensembl
GRCm38.p6 Ensembl4139,348,162 - 139,349,621 (-)Ensembl
Ensembl Acc Id: ENSMUST00000131052
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl4139,074,746 - 139,076,914 (-)Ensembl
GRCm38.p6 Ensembl4139,347,435 - 139,349,603 (-)Ensembl
Ensembl Acc Id: ENSMUST00000139749
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl4139,076,071 - 139,079,844 (-)Ensembl
GRCm38.p6 Ensembl4139,348,760 - 139,352,533 (-)Ensembl
Ensembl Acc Id: ENSMUST00000155257   ⟹   ENSMUSP00000121453
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl4139,076,009 - 139,079,622 (-)Ensembl
GRCm38.p6 Ensembl4139,348,698 - 139,352,311 (-)Ensembl
RefSeq Acc Id: NM_001290810   ⟹   NP_001277739
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm394139,074,751 - 139,079,887 (-)NCBI
GRCm384139,347,440 - 139,352,576 (-)NCBI
Celera4141,134,662 - 141,139,797 (-)NCBI
Sequence:
RefSeq Acc Id: NM_001356476   ⟹   NP_001343405
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm394139,074,751 - 139,079,887 (-)NCBI
GRCm384139,347,440 - 139,352,576 (-)NCBI
Sequence:
RefSeq Acc Id: NM_023536   ⟹   NP_076025
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm394139,074,751 - 139,079,887 (-)NCBI
GRCm384139,347,440 - 139,352,576 (-)NCBI
MGSCv374138,903,360 - 138,908,213 (-)RGD
Celera4141,134,662 - 141,139,797 (-)NCBI
cM Map4 ENTREZGENE
Sequence:
RefSeq Acc Id: NP_076025   ⟸   NM_023536
- Peptide Label: isoform 2
- UniProtKB: A2AMV1 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001277739   ⟸   NM_001290810
- Peptide Label: isoform 1
- UniProtKB: Q9D0I8 (UniProtKB/Swiss-Prot),   Q99JR7 (UniProtKB/Swiss-Prot),   A2AMU9 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001343405   ⟸   NM_001356476
- Peptide Label: isoform 3
- UniProtKB: Q9QYY3 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSMUSP00000030513   ⟸   ENSMUST00000030513
Ensembl Acc Id: ENSMUSP00000099561   ⟸   ENSMUST00000102503
Ensembl Acc Id: ENSMUSP00000121453   ⟸   ENSMUST00000155257
Protein Domains
Large ribosomal subunit protein uL10-like insertion

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q9D0I8-F1-model_v2 AlphaFold Q9D0I8 1-239 view protein structure

Promoters
RGD ID:6836737
Promoter ID:MM_KWN:40369
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:3T3L1_Day0,   3T3L1_Day1,   3T3L1_Day2,   3T3L1_Day3,   3T3L1_Day4,   BoneMarrow_0Hour,   BoneMarrow_2Hour,   BoneMarrow_4Hour,   Brain,   ES_Cell,   Kidney,   Lung,   MEF_B4,   MEF_B6
Transcripts:ENSMUST00000102503,   NM_023536,   NM_146157,   OTTMUST00000023118,   OTTMUST00000023119,   OTTMUST00000023121,   OTTMUST00000023122,   OTTMUST00000023124,   UC008VMF.1,   UC008VMI.1
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv364138,907,676 - 138,908,587 (+)MPROMDB
RGD ID:6885234
Promoter ID:EPDNEW_M6068
Type:initiation region
Name:Mrto4_2
Description:Mus musculus mRNA turnover 4, ribosome maturation factor , transcriptvariant 3, mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_M6069  
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm384139,352,339 - 139,352,399EPDNEW
RGD ID:6885236
Promoter ID:EPDNEW_M6069
Type:initiation region
Name:Mrto4_1
Description:Mus musculus mRNA turnover 4, ribosome maturation factor , transcriptvariant 3, mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_M6068  
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm384139,352,553 - 139,352,613EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:1917152 AgrOrtholog
Ensembl Genes ENSMUSG00000028741 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000030513 ENTREZGENE
  ENSMUST00000030513.13 UniProtKB/TrEMBL
  ENSMUST00000102503 ENTREZGENE
  ENSMUST00000102503.10 UniProtKB/Swiss-Prot
  ENSMUST00000155257.8 UniProtKB/TrEMBL
Gene3D-CATH 3.30.70.1730 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  3.90.105.20 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro Mrt4 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ribosomal_L10-like_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ribosomal_L10P UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ribosome_Assembly_uL10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  RL10_insert_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  RL10P_insert UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:69902 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
MGD MGI:1917152 ENTREZGENE
NCBI Gene 69902 ENTREZGENE
PANTHER MRNA TURNOVER PROTEIN 4 HOMOLOG UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  MRNA TURNOVER PROTEIN 4 MRTO4 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam Ribosomal_L10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  RL10P_insert UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Mrto4 PhenoGen
Superfamily-SCOP SSF160369 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A2AMU9 ENTREZGENE, UniProtKB/TrEMBL
  A2AMV1 ENTREZGENE, UniProtKB/TrEMBL
  D6RCI7_MOUSE UniProtKB/TrEMBL
  MRT4_MOUSE UniProtKB/Swiss-Prot
  Q99JR7 ENTREZGENE
  Q9D0I8 ENTREZGENE
  Q9QYY3 ENTREZGENE, UniProtKB/TrEMBL
UniProt Secondary Q99JR7 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-02-29 Mrto4  mRNA turnover 4, ribosome maturation factor    mRNA turnover 4, homolog (S. cerevisiae)  Symbol and/or name change 5135510 APPROVED
2015-08-04 Mrto4  mRNA turnover 4, homolog (S. cerevisiae)    MRT4, mRNA turnover 4, homolog (S. cerevisiae)  Symbol and/or name change 5135510 APPROVED