CHURC1 (churchill domain containing 1) - Rat Genome Database

Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Advanced Search (OLGA)
Gene: CHURC1 (churchill domain containing 1) Homo sapiens
Analyze
Symbol: CHURC1
Name: churchill domain containing 1
RGD ID: 1312958
HGNC Page HGNC:20099
Description: Predicted to enable zinc ion binding activity. Predicted to be involved in fibroblast growth factor receptor signaling pathway.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: C14orf52; chch; FLJ33064; FLJ51978; FLJ78804; My015; protein Churchill
RGD Orthologs
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381464,914,455 - 64,935,368 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1464,914,361 - 64,944,591 (+)EnsemblGRCh38hg38GRCh38
GRCh371465,381,173 - 65,402,086 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361464,450,893 - 64,471,666 (+)NCBINCBI36Build 36hg18NCBI36
Build 341464,450,892 - 64,471,666NCBI
Celera1445,435,725 - 45,456,498 (+)NCBICelera
Cytogenetic Map14q23.3NCBI
HuRef1445,550,703 - 45,571,710 (+)NCBIHuRef
CHM1_11465,319,246 - 65,340,255 (+)NCBICHM1_1
T2T-CHM13v2.01459,119,323 - 59,140,237 (+)NCBIT2T-CHM13v2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. GOAs Human GO annotations GOA_HUMAN data from the GO Consortium
2. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:12477932   PMID:14651851   PMID:14702039   PMID:15342556   PMID:15489334   PMID:17610897   PMID:20211142   PMID:21360829   PMID:21832049   PMID:21873635   PMID:24981860   PMID:26496610  
PMID:28514442   PMID:32296183   PMID:33961781   PMID:35271311   PMID:35563538  


Genomics

Comparative Map Data
CHURC1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381464,914,455 - 64,935,368 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1464,914,361 - 64,944,591 (+)EnsemblGRCh38hg38GRCh38
GRCh371465,381,173 - 65,402,086 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361464,450,893 - 64,471,666 (+)NCBINCBI36Build 36hg18NCBI36
Build 341464,450,892 - 64,471,666NCBI
Celera1445,435,725 - 45,456,498 (+)NCBICelera
Cytogenetic Map14q23.3NCBI
HuRef1445,550,703 - 45,571,710 (+)NCBIHuRef
CHM1_11465,319,246 - 65,340,255 (+)NCBICHM1_1
T2T-CHM13v2.01459,119,323 - 59,140,237 (+)NCBIT2T-CHM13v2.0
Churc1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391276,812,312 - 76,829,954 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1276,812,312 - 76,829,954 (+)EnsemblGRCm39 Ensembl
GRCm381276,765,538 - 76,783,180 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1276,765,538 - 76,783,180 (+)EnsemblGRCm38mm10GRCm38
MGSCv371277,866,560 - 77,884,167 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361277,684,387 - 77,702,020 (+)NCBIMGSCv36mm8
Celera1277,847,888 - 77,865,485 (+)NCBICelera
Cytogenetic Map12C3NCBI
cM Map1233.73NCBI
Churc1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr86101,203,778 - 101,218,364 (+)NCBIGRCr8
mRatBN7.2695,464,488 - 95,485,208 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl695,470,683 - 95,619,586 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx695,859,353 - 95,873,851 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0696,157,893 - 96,172,388 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0695,586,691 - 95,601,186 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0699,817,439 - 99,831,574 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl699,817,431 - 99,831,576 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.06109,213,899 - 109,228,034 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4699,349,205 - 99,364,032 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1699,352,657 - 99,367,493 (+)NCBI
Celera693,889,940 - 93,904,373 (+)NCBICelera
Cytogenetic Map6q24NCBI
Churc1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554664,855,509 - 5,013,568 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554664,991,571 - 5,013,568 (-)NCBIChiLan1.0ChiLan1.0
CHURC1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21566,028,203 - 66,048,812 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11465,244,726 - 65,265,325 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01445,497,783 - 45,518,393 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11464,377,180 - 64,406,694 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1464,377,180 - 64,398,135 (+)Ensemblpanpan1.1panPan2
CHURC1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1839,301,090 - 39,318,352 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha838,993,476 - 39,010,423 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0839,524,123 - 39,541,093 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl839,523,840 - 39,541,089 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1839,145,417 - 39,162,376 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0839,218,253 - 39,235,185 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0839,577,289 - 39,594,268 (+)NCBIUU_Cfam_GSD_1.0
Churc1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440864065,604,640 - 65,623,823 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049364958,567,894 - 8,713,978 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049364958,567,908 - 8,587,059 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
CHURC1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl788,985,083 - 89,012,131 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1788,985,019 - 89,013,119 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2795,365,933 - 95,394,085 (+)NCBISscrofa10.2Sscrofa10.2susScr3
CHURC1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12442,127,080 - 42,155,572 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2442,127,093 - 42,148,474 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605330,297,389 - 30,326,344 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Churc1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462473435,964,914 - 36,117,852 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462473436,098,613 - 36,117,928 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in CHURC1
9 total Variants

Clinical Variants
Name Type Condition(s) Position(s) Clinical significance
GRCh38/hg38 14q23.1-23.3(chr14:59917051-66750803)x1 copy number loss See cases [RCV000050892] Chr14:59917051..66750803 [GRCh38]
Chr14:60383769..67217521 [GRCh37]
Chr14:59453522..66287274 [NCBI36]
Chr14:14q23.1-23.3		 pathogenic
GRCh38/hg38 14q22.3-23.3(chr14:57041036-67208231)x1 copy number loss See cases [RCV000051521] Chr14:57041036..67208231 [GRCh38]
Chr14:57507754..67674948 [GRCh37]
Chr14:56577507..66744701 [NCBI36]
Chr14:14q22.3-23.3		 pathogenic
GRCh38/hg38 14q11.2-32.33(chr14:20151149-106855263)x3 copy number gain See cases [RCV000135543] Chr14:20151149..106855263 [GRCh38]
Chr14:20619308..107263478 [GRCh37]
Chr14:19689148..106334523 [NCBI36]
Chr14:14q11.2-32.33		 pathogenic
GRCh38/hg38 14q23.2-23.3(chr14:62252700-65753416)x1 copy number loss See cases [RCV000138250] Chr14:62252700..65753416 [GRCh38]
Chr14:62719418..66220134 [GRCh37]
Chr14:61789171..65289887 [NCBI36]
Chr14:14q23.2-23.3		 pathogenic
GRCh38/hg38 14q11.2-32.33(chr14:20043514-106877229)x3 copy number gain See cases [RCV000143373] Chr14:20043514..106877229 [GRCh38]
Chr14:20511673..107285437 [GRCh37]
Chr14:19581513..106356482 [NCBI36]
Chr14:14q11.2-32.33		 pathogenic
GRCh37/hg19 14q11.2-32.33(chr14:19794561-107234280)x3 copy number gain See cases [RCV000446256] Chr14:19794561..107234280 [GRCh37]
Chr14:14q11.2-32.33		 pathogenic
GRCh37/hg19 14q23.2-32.33(chr14:62493932-107285437)x3 copy number gain See cases [RCV000448557] Chr14:62493932..107285437 [GRCh37]
Chr14:14q23.2-32.33		 pathogenic
GRCh37/hg19 14q11.2-32.33(chr14:20511673-107285437) copy number gain See cases [RCV000512041] Chr14:20511673..107285437 [GRCh37]
Chr14:14q11.2-32.33		 pathogenic
NM_001386928.1(CHURC1):c.283G>A (p.Glu95Lys) single nucleotide variant not specified [RCV004307599] Chr14:64932174 [GRCh38]
Chr14:65398892 [GRCh37]
Chr14:14q23.3		 uncertain significance
GRCh37/hg19 14q11.1-32.33(chr14:19000422-107289053)x3 copy number gain not provided [RCV000738412] Chr14:19000422..107289053 [GRCh37]
Chr14:14q11.1-32.33		 pathogenic
GRCh37/hg19 14q11.2-32.33(chr14:19280733-107287663)x3 copy number gain not provided [RCV000738413] Chr14:19280733..107287663 [GRCh37]
Chr14:14q11.2-32.33		 pathogenic
GRCh37/hg19 14q11.2-32.33(chr14:19327823-107287663)x3 copy number gain not provided [RCV000738414] Chr14:19327823..107287663 [GRCh37]
Chr14:14q11.2-32.33		 pathogenic
NM_001386928.1(CHURC1):c.170A>G (p.Tyr57Cys) single nucleotide variant not provided [RCV000964428] Chr14:64924121 [GRCh38]
Chr14:65390839 [GRCh37]
Chr14:14q23.3		 benign|likely benign
NM_001386928.1(CHURC1):c.317G>A (p.Arg106Gln) single nucleotide variant not specified [RCV004288291] Chr14:64932208 [GRCh38]
Chr14:65398926 [GRCh37]
Chr14:14q23.3		 uncertain significance
NM_001386928.1(CHURC1):c.60T>A (p.Asn20Lys) single nucleotide variant not provided [RCV000895760] Chr14:64924011 [GRCh38]
Chr14:65390729 [GRCh37]
Chr14:14q23.3		 likely benign
NM_001386928.1(CHURC1):c.295A>G (p.Ser99Gly) single nucleotide variant not specified [RCV004198918] Chr14:64932186 [GRCh38]
Chr14:65398904 [GRCh37]
Chr14:14q23.3		 uncertain significance
GRCh37/hg19 14q23.1-23.3(chr14:61409856-65742610)x3 copy number gain not provided [RCV001259780] Chr14:61409856..65742610 [GRCh37]
Chr14:14q23.1-23.3		 likely pathogenic
GRCh37/hg19 14q23.2-23.3(chr14:64016496-65834490)x3 copy number gain See cases [RCV002285053] Chr14:64016496..65834490 [GRCh37]
Chr14:14q23.2-23.3		 uncertain significance
GRCh37/hg19 14q22.2-24.3(chr14:54654001-75828024)x3 copy number gain 14q22.2q24.3 duplication [RCV001506967] Chr14:54654001..75828024 [GRCh37]
Chr14:14q22.2-24.3		 likely pathogenic
NC_000014.8:g.(?_64746679)_(66975329_?)del deletion Sulfite oxidase deficiency due to molybdenum cofactor deficiency type C [RCV002007295] Chr14:64746679..66975329 [GRCh37]
Chr14:14q23.2-23.3		 pathogenic
GRCh37/hg19 14q13.3-32.33(chr14:37671058-106985955)x2 copy number gain See cases [RCV002286356] Chr14:37671058..106985955 [GRCh37]
Chr14:14q13.3-32.33		 pathogenic
NM_001386928.1(CHURC1):c.258G>A (p.Met86Ile) single nucleotide variant not specified [RCV004142161] Chr14:64932149 [GRCh38]
Chr14:65398867 [GRCh37]
Chr14:14q23.3		 uncertain significance
NM_145165.3(CHURC1):c.35C>T (p.Ser12Leu) single nucleotide variant not specified [RCV004136944] Chr14:64914449 [GRCh38]
Chr14:65381167 [GRCh37]
Chr14:14q23.3		 uncertain significance
NM_145165.3(CHURC1):c.28G>A (p.Glu10Lys) single nucleotide variant not specified [RCV004128965] Chr14:64914442 [GRCh38]
Chr14:65381160 [GRCh37]
Chr14:14q23.3		 uncertain significance
NM_001386928.1(CHURC1):c.274G>A (p.Gly92Ser) single nucleotide variant not specified [RCV004234702] Chr14:64932165 [GRCh38]
Chr14:65398883 [GRCh37]
Chr14:14q23.3		 uncertain significance
GRCh37/hg19 14q23.1-32.33(chr14:58894502-107227240)x3 copy number gain not provided [RCV003485036] Chr14:58894502..107227240 [GRCh37]
Chr14:14q23.1-32.33		 pathogenic
GRCh37/hg19 14q22.3-24.1(chr14:57588965-68334517)x3 copy number gain not provided [RCV003485034] Chr14:57588965..68334517 [GRCh37]
Chr14:14q22.3-24.1		 likely pathogenic
NM_001386928.1(CHURC1):c.296G>C (p.Ser99Thr) single nucleotide variant not specified [RCV004441719] Chr14:64932187 [GRCh38]
Chr14:65398905 [GRCh37]
Chr14:14q23.3		 uncertain significance
NM_001386928.1(CHURC1):c.250T>C (p.Tyr84His) single nucleotide variant not specified [RCV004610617] Chr14:64932141 [GRCh38]
Chr14:65398859 [GRCh37]
Chr14:14q23.3		 uncertain significance
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:4574
Count of miRNA genes:1047
Interacting mature miRNAs:1258
Transcripts:ENST00000359118, ENST00000547625, ENST00000548752, ENST00000549115, ENST00000551093, ENST00000551947, ENST00000552002, ENST00000556089, ENST00000607599
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCh38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
407217923GWAS866899_Hprotein measurement QTL GWAS866899 (human)6e-09protein measurement146493188764931888Human

Markers in Region
Cda1ka10  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371465,401,517 - 65,401,649UniSTSGRCh37
Build 361464,471,270 - 64,471,402RGDNCBI36
Celera1445,456,102 - 45,456,234RGD
Cytogenetic Map14q23.3UniSTS
HuRef1445,571,141 - 45,571,273UniSTS
GeneMap99-GB4 RH Map14153.24UniSTS
NCBI RH Map14647.8UniSTS
RH68912  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371465,400,640 - 65,400,776UniSTSGRCh37
Build 361464,470,393 - 64,470,529RGDNCBI36
Celera1445,455,225 - 45,455,361RGD
Cytogenetic Map14q23.3UniSTS
HuRef1445,570,264 - 45,570,400UniSTS
GeneMap99-GB4 RH Map14153.24UniSTS
NCBI RH Map14647.8UniSTS
RH123549  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371465,393,684 - 65,394,003UniSTSGRCh37
Build 361464,463,437 - 64,463,756RGDNCBI36
Celera1445,448,269 - 45,448,588RGD
Cytogenetic Map14q23.3UniSTS
HuRef1445,563,308 - 45,563,627UniSTS
TNG Radiation Hybrid Map1420810.0UniSTS
D14S712E  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371465,399,957 - 65,400,064UniSTSGRCh37
Build 361464,469,710 - 64,469,817RGDNCBI36
Celera1445,454,542 - 45,454,649RGD
Cytogenetic Map14q23.3UniSTS
HuRef1445,569,581 - 45,569,688UniSTS
SHGC-33304  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371465,398,889 - 65,399,018UniSTSGRCh37
Build 361464,468,642 - 64,468,771RGDNCBI36
Celera1445,453,474 - 45,453,603RGD
Cytogenetic Map14q23.3UniSTS
HuRef1445,568,513 - 45,568,642UniSTS
TNG Radiation Hybrid Map1420813.0UniSTS
Stanford-G3 RH Map142258.0UniSTS
NCBI RH Map14653.0UniSTS
GeneMap99-G3 RH Map142306.0UniSTS
RH44676  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371465,398,851 - 65,399,018UniSTSGRCh37
Build 361464,468,604 - 64,468,771RGDNCBI36
Celera1445,453,436 - 45,453,603RGD
Cytogenetic Map14q23.3UniSTS
HuRef1445,568,475 - 45,568,642UniSTS
GeneMap99-GB4 RH Map14153.04UniSTS
NCBI RH Map14647.8UniSTS
SGC33171  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371465,399,760 - 65,399,909UniSTSGRCh37
Build 361464,469,513 - 64,469,662RGDNCBI36
Celera1445,454,345 - 45,454,494RGD
Cytogenetic Map14q23.3UniSTS
HuRef1445,569,384 - 45,569,533UniSTS
GeneMap99-GB4 RH Map14153.24UniSTS
Whitehead-RH Map14228.7UniSTS
NCBI RH Map14647.8UniSTS
A006H20  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371465,399,098 - 65,399,318UniSTSGRCh37
Build 361464,468,851 - 64,469,071RGDNCBI36
Celera1445,453,683 - 45,453,903RGD
Cytogenetic Map14q23.3UniSTS
HuRef1445,568,722 - 45,568,942UniSTS
GeneMap99-GB4 RH Map14153.24UniSTS
NCBI RH Map14647.8UniSTS
A002U27  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371465,401,592 - 65,401,698UniSTSGRCh37
Build 361464,471,345 - 64,471,451RGDNCBI36
Celera1445,456,177 - 45,456,283RGD
Cytogenetic Map14q23.3UniSTS
HuRef1445,571,216 - 45,571,322UniSTS
GeneMap99-GB4 RH Map14153.04UniSTS
NCBI RH Map14647.8UniSTS
WI-11285  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371465,399,188 - 65,399,337UniSTSGRCh37
Build 361464,468,941 - 64,469,090RGDNCBI36
Celera1445,453,773 - 45,453,922RGD
Cytogenetic Map14q23.3UniSTS
HuRef1445,568,812 - 45,568,961UniSTS
GeneMap99-GB4 RH Map14153.24UniSTS
Whitehead-RH Map14228.7UniSTS
NCBI RH Map14647.8UniSTS
G32354  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371465,399,098 - 65,399,318UniSTSGRCh37
Celera1445,453,683 - 45,453,903UniSTS
Cytogenetic Map14q23.3UniSTS
HuRef1445,568,722 - 45,568,942UniSTS
D11S3316  
Human AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map6p21UniSTS
Cytogenetic Map16q24UniSTS
Cytogenetic Map12q24.31UniSTS
Cytogenetic Map14q23.3UniSTS
Cytogenetic Map22q13.1UniSTS
Cytogenetic Map16p13.3UniSTS
Cytogenetic Map17q22UniSTS
Cytogenetic Map17p13.1UniSTS
Cytogenetic Map5q33.3UniSTS
Cytogenetic Map10q11.1UniSTS
Cytogenetic MapXp11.4UniSTS
Cytogenetic Map1q23.1UniSTS
Cytogenetic Map10q22UniSTS
Cytogenetic Map2q31.1UniSTS
Cytogenetic Map3q21.3UniSTS
Cytogenetic Map7p15-p14UniSTS
Cytogenetic Map2p11.2UniSTS
Cytogenetic Map4p12UniSTS
Cytogenetic Map1q42.1UniSTS
Cytogenetic Map16q22.1UniSTS
Cytogenetic Map18q11.2UniSTS
Cytogenetic Map11q24.2UniSTS
Cytogenetic Map7q22.1UniSTS
Cytogenetic Map2p12-p11.2UniSTS
Cytogenetic Map19q13.3UniSTS
Cytogenetic MapXp22UniSTS
Cytogenetic Map11q23.3UniSTS
Cytogenetic Map11q13.2UniSTS
Cytogenetic Map11q13UniSTS
Cytogenetic Map12q13-q14UniSTS
Cytogenetic Map8p11.22UniSTS
Cytogenetic Map1q32UniSTS
Cytogenetic Map11q12-q13.2UniSTS
Cytogenetic Map1p34UniSTS
Cytogenetic Map20p13UniSTS
Cytogenetic Map12q22UniSTS
Cytogenetic Map1p36.32UniSTS
Cytogenetic Map20q13.13UniSTS
Cytogenetic Map6q22.31UniSTS
Cytogenetic Map2q11.2UniSTS
Cytogenetic Map1p21UniSTS
Cytogenetic Map11q22.3UniSTS
Cytogenetic Map16q12.2UniSTS
Cytogenetic Map19q13.32UniSTS
Cytogenetic Map4q31.3UniSTS
Cytogenetic Map20q13.1UniSTS
Cytogenetic Map16p11.2UniSTS
Cytogenetic Map12q13.11-q14.3UniSTS
Cytogenetic Map3q13.33UniSTS
Cytogenetic Map6p22.2UniSTS
Cytogenetic Map3q26.33UniSTS
Cytogenetic Map6p21.3UniSTS
Cytogenetic Map8q24.11UniSTS
Cytogenetic Map15q13.1UniSTS
Cytogenetic Map10q22.2UniSTS
Cytogenetic Map2p14UniSTS
Cytogenetic Map15q11.2UniSTS
Cytogenetic Map19q13.12UniSTS
Cytogenetic Map7q11.23UniSTS
Cytogenetic Map11p15.5UniSTS
Cytogenetic Map9q33.3UniSTS
Cytogenetic MapXq24UniSTS
Cytogenetic Map17q25.3UniSTS
Cytogenetic Map10q26.13UniSTS
Cytogenetic Map19p13.3UniSTS
Cytogenetic Map16p13.2UniSTS
Cytogenetic Map15q14-q15UniSTS
Cytogenetic Map15q21.2UniSTS
Cytogenetic Map19q13UniSTS
Cytogenetic Map6p21.31UniSTS
Cytogenetic Map5q13UniSTS
Cytogenetic Map5q13.2UniSTS
Cytogenetic Map17q25.1UniSTS
Cytogenetic Map2p15UniSTS
Cytogenetic Map10q26.1UniSTS
Cytogenetic Map4q26UniSTS
Cytogenetic Map1q25.2UniSTS
Cytogenetic Map4q21.1UniSTS
Cytogenetic Map22q11.23UniSTS
Cytogenetic Map19p13.2UniSTS
Cytogenetic Map15q25.2UniSTS
Cytogenetic Map13q13.1UniSTS
Cytogenetic Map6p21.2UniSTS
Cytogenetic Map11q13.1UniSTS
Cytogenetic Map16p12.2UniSTS
Cytogenetic Map13q14UniSTS
Cytogenetic Map7q21-q22UniSTS
Cytogenetic Map12qUniSTS
Cytogenetic Map10q11.23UniSTS
Cytogenetic Map1p34.1UniSTS
Cytogenetic Map3p21.31UniSTS
Cytogenetic Map14q31UniSTS


Expression

RNA-SEQ Expression

adipose tissue
alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
entire extraembryonic component
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
pharyngeal arch
renal system
reproductive system
respiratory system
sensory system
visual system
1204 2439 2788 2253 4974 1726 2351 6 624 1951 465 2270 7306 6472 53 3734 1 852 1744 1617 175 1

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001204064 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001386928 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_145165 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AF060510 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK057626 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK296141 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK315905 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AL135745 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AL139022 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AV734503 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AX970436 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC010517 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC020550 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BM453839 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BP305870 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH471061 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CP068264 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  KF455908 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENST00000547625   ⟹   ENSP00000449184
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1464,924,010 - 64,930,937 (+)Ensembl
Ensembl Acc Id: ENST00000548752   ⟹   ENSP00000450165
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1464,914,415 - 64,932,320 (+)Ensembl
Ensembl Acc Id: ENST00000549115   ⟹   ENSP00000448050
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1464,914,455 - 64,935,368 (+)Ensembl
Ensembl Acc Id: ENST00000551093   ⟹   ENSP00000446610
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1464,914,477 - 64,944,056 (+)Ensembl
Ensembl Acc Id: ENST00000551947   ⟹   ENSP00000446697
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1464,914,443 - 64,944,591 (+)Ensembl
Ensembl Acc Id: ENST00000552002   ⟹   ENSP00000450144
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1464,914,455 - 64,935,368 (+)Ensembl
Ensembl Acc Id: ENST00000556089
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1464,914,458 - 64,924,484 (+)Ensembl
Ensembl Acc Id: ENST00000607599   ⟹   ENSP00000475473
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1464,914,361 - 64,935,368 (+)Ensembl
RefSeq Acc Id: NM_001204064   ⟹   NP_001190993
RefSeq Status: VALIDATED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381464,914,455 - 64,935,368 (+)NCBI
GRCh371465,381,079 - 65,410,635 (+)NCBI
HuRef1445,550,703 - 45,571,710 (+)ENTREZGENE
CHM1_11465,319,246 - 65,340,255 (+)NCBI
T2T-CHM13v2.01459,119,323 - 59,140,237 (+)NCBI
Sequence:
RefSeq Acc Id: NM_001386928   ⟹   NP_001373857
RefSeq Status: VALIDATED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381464,914,455 - 64,935,368 (+)NCBI
T2T-CHM13v2.01459,119,323 - 59,140,237 (+)NCBI
Sequence:
RefSeq Acc Id: NM_145165   ⟹   NP_660148
RefSeq Status: VALIDATED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381464,914,455 - 64,935,368 (+)NCBI
GRCh371465,381,079 - 65,410,635 (+)NCBI
Build 361464,450,893 - 64,471,666 (+)NCBI Archive
Celera1445,435,725 - 45,456,498 (+)RGD
HuRef1445,550,703 - 45,571,710 (+)ENTREZGENE
CHM1_11465,319,246 - 65,340,255 (+)NCBI
T2T-CHM13v2.01459,119,323 - 59,140,237 (+)NCBI
Sequence:
RefSeq Acc Id: NP_660148   ⟸   NM_145165
- Peptide Label: isoform 1
- Sequence:
RefSeq Acc Id: NP_001190993   ⟸   NM_001204064
- Peptide Label: isoform 3
- Sequence:
Ensembl Acc Id: ENSP00000449184   ⟸   ENST00000547625
Ensembl Acc Id: ENSP00000450165   ⟸   ENST00000548752
Ensembl Acc Id: ENSP00000448050   ⟸   ENST00000549115
Ensembl Acc Id: ENSP00000446610   ⟸   ENST00000551093
Ensembl Acc Id: ENSP00000446697   ⟸   ENST00000551947
Ensembl Acc Id: ENSP00000450144   ⟸   ENST00000552002
Ensembl Acc Id: ENSP00000475473   ⟸   ENST00000607599
RefSeq Acc Id: NP_001373857   ⟸   NM_001386928
- Peptide Label: isoform 2
- UniProtKB: Q8WUH1 (UniProtKB/Swiss-Prot),   G3V214 (UniProtKB/Swiss-Prot),   G3V1X3 (UniProtKB/Swiss-Prot),   B3KQ81 (UniProtKB/Swiss-Prot),   A0A0C4DGJ7 (UniProtKB/Swiss-Prot),   Q9H3K7 (UniProtKB/Swiss-Prot)

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q8WUH1-F1-model_v2 AlphaFold Q8WUH1 1-112 view protein structure

Promoters
RGD ID:6791374
Promoter ID:HG_KWN:19591
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:CD4+TCell,   CD4+TCell_12Hour,   CD4+TCell_2Hour,   HeLa_S3,   Jurkat,   K562,   Lymphoblastoid,   NB4
Transcripts:NM_145165,   UC001XHW.1,   UC010AQJ.1
Position:
Human AssemblyChrPosition (strand)Source
Build 361464,450,651 - 64,451,151 (+)MPROMDB
RGD ID:7227887
Promoter ID:EPDNEW_H19690
Type:initiation region
Name:CHURC1_1
Description:churchill domain containing 1
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_H19692  
Experiment Methods:Single-end sequencing.
Position:
Human AssemblyChrPosition (strand)Source
GRCh381464,914,458 - 64,914,518EPDNEW
RGD ID:7227893
Promoter ID:EPDNEW_H19692
Type:initiation region
Name:CHURC1_2
Description:churchill domain containing 1
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_H19690  
Experiment Methods:Single-end sequencing.; Paired-end sequencing.
Position:
Human AssemblyChrPosition (strand)Source
GRCh381464,923,991 - 64,924,051EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene HGNC:20099 AgrOrtholog
COSMIC CHURC1 COSMIC
Ensembl Genes ENSG00000258289 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Transcript ENST00000547625.1 UniProtKB/TrEMBL
  ENST00000548752 ENTREZGENE
  ENST00000548752.7 UniProtKB/Swiss-Prot
  ENST00000549115 ENTREZGENE
  ENST00000549115.7 UniProtKB/Swiss-Prot
  ENST00000551093.6 UniProtKB/TrEMBL
  ENST00000551947.6 UniProtKB/TrEMBL
  ENST00000552002.7 UniProtKB/Swiss-Prot
  ENST00000607599 ENTREZGENE
  ENST00000607599.6 UniProtKB/Swiss-Prot
Gene3D-CATH 2.60.40.4240 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
GTEx ENSG00000258289 GTEx
HGNC ID HGNC:20099 ENTREZGENE
Human Proteome Map CHURC1 Human Proteome Map
InterPro Churchill_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Transcrpt_activator_Churchill UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report hsa:91612 UniProtKB/Swiss-Prot
NCBI Gene 91612 ENTREZGENE
OMIM 608577 OMIM
PANTHER PROTEIN CHURCHILL UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PTHR31931 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam Churchill UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PharmGKB PA134982480 PharmGKB
UniProt A0A0C4DGJ7 ENTREZGENE
  B3KQ81 ENTREZGENE
  B7Z3N2_HUMAN UniProtKB/TrEMBL
  CHUR_HUMAN UniProtKB/Swiss-Prot
  G3V1X3 ENTREZGENE
  G3V214 ENTREZGENE
  H0YHB4_HUMAN UniProtKB/TrEMBL
  H0YID9_HUMAN UniProtKB/TrEMBL
  Q8WUH1 ENTREZGENE
  Q9H3K7 ENTREZGENE
UniProt Secondary A0A0C4DGJ7 UniProtKB/Swiss-Prot
  B3KQ81 UniProtKB/Swiss-Prot
  G3V1X3 UniProtKB/Swiss-Prot
  G3V214 UniProtKB/Swiss-Prot
  H0YHA3 UniProtKB/TrEMBL
  Q9H3K7 UniProtKB/Swiss-Prot