CHURC1 (churchill domain containing 1) - Rat Genome Database

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Gene: CHURC1 (churchill domain containing 1) Canis lupus familiaris
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Symbol: CHURC1
Name: churchill domain containing 1
RGD ID: 12342331
Description: ENCODES a protein that exhibits metal ion binding (inferred); zinc ion binding (inferred); INVOLVED IN fibroblast growth factor receptor signaling pathway (inferred); positive regulation of DNA-templated transcription (inferred); ASSOCIATED WITH genetic disease (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: protein Churchill
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: CanFam3.1 - Dog CanFam3.1 Assembly
Position:
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1839,301,090 - 39,318,352 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha838,993,476 - 39,010,423 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0839,524,123 - 39,541,093 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl839,523,840 - 39,541,089 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1839,145,417 - 39,162,376 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0839,218,253 - 39,235,185 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0839,577,289 - 39,594,268 (+)NCBIUU_Cfam_GSD_1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Molecular Function

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
CHURC1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1839,301,090 - 39,318,352 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha838,993,476 - 39,010,423 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0839,524,123 - 39,541,093 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl839,523,840 - 39,541,089 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1839,145,417 - 39,162,376 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0839,218,253 - 39,235,185 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0839,577,289 - 39,594,268 (+)NCBIUU_Cfam_GSD_1.0
CHURC1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381464,914,455 - 64,935,368 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1464,914,361 - 64,944,591 (+)EnsemblGRCh38hg38GRCh38
GRCh371465,381,173 - 65,402,086 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361464,450,893 - 64,471,666 (+)NCBINCBI36Build 36hg18NCBI36
Build 341464,450,892 - 64,471,666NCBI
Celera1445,435,725 - 45,456,498 (+)NCBICelera
Cytogenetic Map14q23.3NCBI
HuRef1445,550,703 - 45,571,710 (+)NCBIHuRef
CHM1_11465,319,246 - 65,340,255 (+)NCBICHM1_1
T2T-CHM13v2.01459,119,323 - 59,140,237 (+)NCBIT2T-CHM13v2.0
Churc1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391276,812,312 - 76,829,954 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1276,812,312 - 76,829,954 (+)EnsemblGRCm39 Ensembl
GRCm381276,765,538 - 76,783,180 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1276,765,538 - 76,783,180 (+)EnsemblGRCm38mm10GRCm38
MGSCv371277,866,560 - 77,884,167 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361277,684,387 - 77,702,020 (+)NCBIMGSCv36mm8
Celera1277,847,888 - 77,865,485 (+)NCBICelera
Cytogenetic Map12C3NCBI
cM Map1233.73NCBI
Churc1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr86101,203,778 - 101,218,364 (+)NCBIGRCr8
mRatBN7.2695,464,488 - 95,485,208 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl695,470,683 - 95,619,586 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx695,859,353 - 95,873,851 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0696,157,893 - 96,172,388 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0695,586,691 - 95,601,186 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0699,817,439 - 99,831,574 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl699,817,431 - 99,831,576 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.06109,213,899 - 109,228,034 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4699,349,205 - 99,364,032 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1699,352,657 - 99,367,493 (+)NCBI
Celera693,889,940 - 93,904,373 (+)NCBICelera
Cytogenetic Map6q24NCBI
Churc1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554664,855,509 - 5,013,568 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554664,991,571 - 5,013,568 (-)NCBIChiLan1.0ChiLan1.0
CHURC1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21566,028,203 - 66,048,812 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11465,244,726 - 65,265,325 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01445,497,783 - 45,518,393 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11464,377,180 - 64,406,694 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1464,377,180 - 64,398,135 (+)Ensemblpanpan1.1panPan2
Churc1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440864065,604,640 - 65,623,823 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049364958,567,894 - 8,713,978 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049364958,567,908 - 8,587,059 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
CHURC1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl788,985,083 - 89,012,131 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1788,985,019 - 89,013,119 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2795,365,933 - 95,394,085 (+)NCBISscrofa10.2Sscrofa10.2susScr3
CHURC1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12442,127,080 - 42,155,572 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2442,127,093 - 42,148,474 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605330,297,389 - 30,326,344 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Churc1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462473435,964,914 - 36,117,852 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462473436,098,613 - 36,117,928 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in CHURC1
250 total Variants

Expression


Sequence


RefSeq Acc Id: ENSCAFT00845004399   ⟹   ENSCAFP00845003516
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl839,523,840 - 39,541,089 (+)Ensembl
RefSeq Acc Id: XM_038483486   ⟹   XP_038339414
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.1839,145,417 - 39,162,376 (+)NCBI
RefSeq Acc Id: XM_038483488   ⟹   XP_038339416
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.1839,145,417 - 39,159,635 (+)NCBI
RefSeq Acc Id: XM_038544952   ⟹   XP_038400880
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.0839,577,289 - 39,594,268 (+)NCBI
RefSeq Acc Id: XM_038544953   ⟹   XP_038400881
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.0839,577,289 - 39,591,525 (+)NCBI
RefSeq Acc Id: XM_038589309   ⟹   XP_038445237
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
Dog10K_Boxer_Tasha838,993,476 - 39,007,682 (+)NCBI
RefSeq Acc Id: XM_038609066   ⟹   XP_038464994
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.0839,218,253 - 39,235,185 (+)NCBI
RefSeq Acc Id: XM_038609067   ⟹   XP_038464995
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.0839,218,253 - 39,232,443 (+)NCBI
RefSeq Acc Id: XM_038673867   ⟹   XP_038529795
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0839,524,123 - 39,541,093 (+)NCBI
RefSeq Acc Id: XM_038673868   ⟹   XP_038529796
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0839,524,123 - 39,538,352 (+)NCBI
RefSeq Acc Id: XM_847755   ⟹   XP_852848
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1839,301,090 - 39,318,352 (+)NCBI
Dog10K_Boxer_Tasha838,993,476 - 39,010,423 (+)NCBI
Sequence:
RefSeq Acc Id: XP_852848   ⟸   XM_847755
- Peptide Label: isoform X1
- UniProtKB: A0A8C0NVQ5 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_038339414   ⟸   XM_038483486
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038339416   ⟸   XM_038483488
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038464994   ⟸   XM_038609066
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038464995   ⟸   XM_038609067
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038529795   ⟸   XM_038673867
- Peptide Label: isoform X1
- UniProtKB: A0A8C0NVQ5 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038529796   ⟸   XM_038673868
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038445237   ⟸   XM_038589309
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038400880   ⟸   XM_038544952
- Peptide Label: isoform X1
- UniProtKB: A0A8C0NVQ5 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038400881   ⟸   XM_038544953
- Peptide Label: isoform X2
RefSeq Acc Id: ENSCAFP00845003516   ⟸   ENSCAFT00845004399

Promoters
RGD ID:13684243
Promoter ID:EPDNEW_C2313
Type:multiple initiation site
Name:CHURC1_1
Description:churchill domain containing 1
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1839,301,148 - 39,301,208EPDNEW

Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCAFG00000052947 UniProtKB/TrEMBL
  ENSCAFG00030018855 UniProtKB/TrEMBL
  ENSCAFG00040008428 UniProtKB/TrEMBL
  ENSCAFG00845002489 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSCAFT00000039316.4 UniProtKB/TrEMBL
  ENSCAFT00030034762.1 UniProtKB/TrEMBL
  ENSCAFT00040015784.1 UniProtKB/TrEMBL
  ENSCAFT00845004399.1 UniProtKB/TrEMBL
Gene3D-CATH 2.60.40.4240 UniProtKB/TrEMBL
InterPro Churchill_sf UniProtKB/TrEMBL
  Transcrpt_activator_Churchill UniProtKB/TrEMBL
NCBI Gene CHURC1 ENTREZGENE
PANTHER PROTEIN CHURCHILL UniProtKB/TrEMBL
  PTHR31931 UniProtKB/TrEMBL
Pfam Churchill UniProtKB/TrEMBL
UniProt A0A8C0NVQ5 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I3ML45_CANLF UniProtKB/TrEMBL
  A0A8P0NMZ0_CANLF UniProtKB/TrEMBL
VGNC ID VGNC:39262 ENTREZGENE