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Gene: Otud7b (OTU deubiquitinase 7B) Rattus norvegicus
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Symbol: Otud7b
Name: OTU deubiquitinase 7B
Description: Predicted to have K63-linked polyubiquitin modification-dependent protein binding activity; Lys48-specific deubiquitinase activity; and thiol-dependent ubiquitin-specific protease activity. Predicted to be involved in several processes, including negative regulation of I-kappaB kinase/NF-kappaB signaling; negative regulation of interleukin-8 production; and protein deubiquitination. Predicted to localize to the cytoplasm and nucleus. Orthologous to human OTUD7B (OTU deubiquitinase 7B); INTERACTS WITH 1,2-dimethylhydrazine; 2,2',4,4'-Tetrabromodiphenyl ether; 2,2',5,5'-tetrachlorobiphenyl.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: cellular zinc finger anti-NF-kappaB Cezanne; LOC310677; OTU domain containing 7B; OTU domain-containing protein 7B; RGD1308111; similar to zinc finger protein Cezanne
Orthologs:
Homo sapiens (human) : OTUD7B (OTU deubiquitinase 7B)  HGNC  Alliance
Mus musculus (house mouse) : Otud7b (OTU domain containing 7B)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Otud7b (OTU deubiquitinase 7B)
Pan paniscus (bonobo/pygmy chimpanzee) : OTUD7B (OTU deubiquitinase 7B)
Canis lupus familiaris (dog) : OTUD7B (OTU deubiquitinase 7B)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Otud7b (OTU deubiquitinase 7B)
Sus scrofa (pig) : OTUD7B (OTU deubiquitinase 7B)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.02198,231,353 - 198,302,220 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.02217,720,895 - 217,789,205 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.42190,905,522 - 190,964,454 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.12190,868,275 - 190,938,314 (+)NCBI
Celera2176,190,012 - 176,247,856 (+)NCBICelera
Cytogenetic Map2q34NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 5.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
 
More on Otud7b
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1308111
Created: 2005-01-12
Species: Rattus norvegicus
Last Modified: 2019-08-20
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.