Advanced Search (OLGA)

Gene: Pask (PAS domain containing serine/threonine kinase) Rattus norvegicus

Subscribe to Updates

Analyze

Symbol:

Pask

Name:

PAS domain containing serine/threonine kinase

RGD ID:

1306146

Description:

Predicted to enable phosphatidylinositol binding activity and protein serine/threonine kinase activity. Predicted to be involved in several processes, including negative regulation of glycogen biosynthetic process; protein autophosphorylation; and regulation of glucagon secretion. Predicted to be active in cytosol and nucleus. Orthologous to human PASK (PAS domain containing serine/threonine kinase); INTERACTS WITH 1,3-dinitrobenzene; 1-naphthyl isothiocyanate; 6-propyl-2-thiouracil.

Type:

protein-coding

RefSeq Status:

VALIDATED

Previously known as:

LOC301617; MGC93882; PAS domain-containing serine/threonine-protein kinase

RGD Orthologs

Alliance Orthologs

More Info

more info ...

Latest Assembly:

GRCr8 - GRCr8 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	9	101,291,673 - 101,333,288 (-)	NCBI		GRCr8
mRatBN7.2	9	93,844,275 - 93,886,036 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	9	93,844,278 - 93,885,111 (-)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	9	102,279,835 - 102,320,665 (-)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	9	107,415,644 - 107,456,467 (-)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	9	105,771,786 - 105,812,609 (-)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	9	100,450,595 - 100,479,719 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	9	100,450,586 - 100,479,868 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	9	100,106,950 - 100,136,074 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	9	92,582,177 - 92,623,004 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	9	92,786,946 - 92,827,773 (-)	NCBI
Celera	9	91,379,229 - 91,420,042 (-)	NCBI		Celera
Cytogenetic Map	9	q36	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
Pask	Rat	Bethlem Myopathy 1A		ISO	PASK (Homo sapiens)	8554872	ClinVar Annotator: match by term: Bethlem myopathy 1A	ClinVar	PMID:26004199 and PMID:28492532
Pask	Rat	chromosome 2q37 deletion syndrome		ISO	PASK (Homo sapiens)	8554872	ClinVar Annotator: match by term: Chromosome 2q37 deletion syndrome	ClinVar	PMID:25741868
Pask	Rat	chronic kidney disease		ISO	PASK (Homo sapiens)	8554872	ClinVar Annotator: match by term: Chronic kidney disease	ClinVar	PMID:25741868
Pask	Rat	D-2-hydroxyglutaric aciduria 1		ISO	PASK (Homo sapiens)	8554872	ClinVar Annotator: match by term: D-2-hydroxyglutaric aciduria 1	ClinVar	PMID:16081310 more ...
Pask	Rat	hereditary spastic paraplegia 30		ISO	PASK (Homo sapiens)	8554872	ClinVar Annotator: match by term: Hereditary spastic paraplegia 30	ClinVar	PMID:16081310 more ...
Pask	Rat	intellectual disability		ISO	PASK (Homo sapiens)	8554872	ClinVar Annotator: match by term: Intellectual disability	ClinVar

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
Pask	Rat	autistic disorder		ISO	PASK (Homo sapiens)	11554173	CTD Direct Evidence: marker/mechanism	CTD	PMID:19365831
Pask	Rat	chromosome 2q37 deletion syndrome		ISO	PASK (Homo sapiens)	11554173	CTD Direct Evidence: marker/mechanism	CTD	PMID:19365831

Only show annotations with direct experimental evidence (0 objects hidden)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
Pask	Rat	1,3-dinitrobenzene	decreases expression	EXP		6480464	3-dinitrobenzene results in decreased expression of PASK mRNA	CTD	PMID:21983209
Pask	Rat	1-naphthyl isothiocyanate	increases expression	EXP		6480464	1-Naphthylisothiocyanate results in increased expression of PASK mRNA	CTD	PMID:30723492
Pask	Rat	2,2',4,4',5,5'-hexachlorobiphenyl	multiple interactions	ISO	Pask (Mus musculus)	6480464	[2 more ...	CTD	PMID:25510870
Pask	Rat	2,2',5,5'-tetrachlorobiphenyl	multiple interactions	ISO	Pask (Mus musculus)	6480464	[2 more ...	CTD	PMID:25510870
Pask	Rat	2,2',5,5'-tetrachlorobiphenyl	decreases expression	ISO	PASK (Homo sapiens)	6480464	2 more ...	CTD	PMID:36804509
Pask	Rat	2,3,7,8-tetrachlorodibenzodioxine	affects expression	ISO	Pask (Mus musculus)	6480464	Tetrachlorodibenzodioxin affects the expression of PASK mRNA	CTD	PMID:21570461 and PMID:26377647
Pask	Rat	4,4'-sulfonyldiphenol	increases methylation	ISO	PASK (Homo sapiens)	6480464	bisphenol S results in increased methylation of PASK gene	CTD	PMID:31601247
Pask	Rat	6-propyl-2-thiouracil	increases expression	EXP		6480464	Propylthiouracil results in increased expression of PASK mRNA	CTD	PMID:22504374
Pask	Rat	acetamide	increases expression	EXP		6480464	acetamide results in increased expression of PASK mRNA	CTD	PMID:31881176
Pask	Rat	acrylamide	increases expression	EXP		6480464	Acrylamide results in increased expression of PASK mRNA	CTD	PMID:28959563
Pask	Rat	acrylamide	decreases expression	ISO	PASK (Homo sapiens)	6480464	Acrylamide results in decreased expression of PASK mRNA	CTD	PMID:32763439
Pask	Rat	aflatoxin B1	increases expression	ISO	PASK (Homo sapiens)	6480464	Aflatoxin B1 results in increased expression of PASK mRNA	CTD	PMID:22100608
Pask	Rat	aflatoxin B1	increases methylation	ISO	PASK (Homo sapiens)	6480464	Aflatoxin B1 results in increased methylation of PASK gene	CTD	PMID:27153756
Pask	Rat	aristolochic acid A	decreases expression	ISO	PASK (Homo sapiens)	6480464	aristolochic acid I results in decreased expression of PASK mRNA	CTD	PMID:33212167
Pask	Rat	arsane	multiple interactions	ISO	PASK (Homo sapiens)	6480464	[sodium arsenite results in increased abundance of Arsenic] which results in decreased expression of PASK mRNA	CTD	PMID:39836092
Pask	Rat	arsenic atom	multiple interactions	ISO	PASK (Homo sapiens)	6480464	[sodium arsenite results in increased abundance of Arsenic] which results in decreased expression of PASK mRNA	CTD	PMID:39836092
Pask	Rat	azathioprine	decreases expression	ISO	PASK (Homo sapiens)	6480464	Azathioprine results in decreased expression of PASK mRNA	CTD	PMID:22623647
Pask	Rat	benzo[a]pyrene	increases expression	ISO	PASK (Homo sapiens)	6480464	Benzo(a)pyrene results in increased expression of PASK mRNA	CTD	PMID:32234424
Pask	Rat	benzo[b]fluoranthene	increases expression	ISO	Pask (Mus musculus)	6480464	benzo(b)fluoranthene results in increased expression of PASK mRNA	CTD	PMID:26377693
Pask	Rat	bis(2-ethylhexyl) phthalate	increases expression	ISO	Pask (Mus musculus)	6480464	Diethylhexyl Phthalate results in increased expression of PASK mRNA	CTD	PMID:34319233
Pask	Rat	bisphenol A	decreases expression	EXP		6480464	bisphenol A results in decreased expression of PASK mRNA	CTD	PMID:25181051
Pask	Rat	bisphenol A	affects methylation	ISO	PASK (Homo sapiens)	6480464	bisphenol A affects the methylation of PASK gene	CTD	PMID:31601247
Pask	Rat	cadmium dichloride	increases expression	ISO	PASK (Homo sapiens)	6480464	Cadmium Chloride results in increased expression of PASK mRNA	CTD	PMID:12160620
Pask	Rat	caffeine	increases phosphorylation	ISO	PASK (Homo sapiens)	6480464	Caffeine results in increased phosphorylation of PASK protein	CTD	PMID:35688186
Pask	Rat	calcitriol	multiple interactions	EXP		6480464	[Calcium co-treated with Calcitriol] affects the expression of PASK mRNA	CTD	PMID:15913539
Pask	Rat	calcium atom	multiple interactions	EXP		6480464	[Calcium co-treated with Calcitriol] affects the expression of PASK mRNA	CTD	PMID:15913539
Pask	Rat	calcium(0)	multiple interactions	EXP		6480464	[Calcium co-treated with Calcitriol] affects the expression of PASK mRNA	CTD	PMID:15913539
Pask	Rat	carbamazepine	affects expression	ISO	PASK (Homo sapiens)	6480464	Carbamazepine affects the expression of PASK mRNA	CTD	PMID:25979313
Pask	Rat	carbon nanotube	increases expression	ISO	Pask (Mus musculus)	6480464	Nanotubes more ...	CTD	PMID:25554681
Pask	Rat	cefaloridine	increases expression	EXP		6480464	Cephaloridine results in increased expression of PASK mRNA	CTD	PMID:18500788
Pask	Rat	chlorpyrifos	decreases expression	ISO	Pask (Mus musculus)	6480464	Chlorpyrifos results in decreased expression of PASK mRNA	CTD	PMID:37019170
Pask	Rat	choline	multiple interactions	ISO	Pask (Mus musculus)	6480464	[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of PASK mRNA	CTD	PMID:20938992
Pask	Rat	cobalt dichloride	decreases expression	ISO	PASK (Homo sapiens)	6480464	cobaltous chloride results in decreased expression of PASK mRNA	CTD	PMID:19376846
Pask	Rat	copper(II) sulfate	decreases expression	ISO	PASK (Homo sapiens)	6480464	Copper Sulfate results in decreased expression of PASK mRNA	CTD	PMID:19549813
Pask	Rat	cyclosporin A	decreases expression	ISO	PASK (Homo sapiens)	6480464	Cyclosporine results in decreased expression of PASK mRNA	CTD	PMID:20106945 more ...
Pask	Rat	Dibutyl phosphate	affects expression	ISO	PASK (Homo sapiens)	6480464	di-n-butylphosphoric acid affects the expression of PASK mRNA	CTD	PMID:37042841
Pask	Rat	dioxygen	decreases expression	ISO	PASK (Homo sapiens)	6480464	Oxygen deficiency results in decreased expression of PASK mRNA	CTD	PMID:26516004
Pask	Rat	dorsomorphin	multiple interactions	ISO	PASK (Homo sapiens)	6480464	[NOG protein co-treated with Phenylmercuric Acetate co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of PASK mRNA	CTD	PMID:27188386
Pask	Rat	endosulfan	decreases expression	EXP		6480464	Endosulfan results in decreased expression of PASK mRNA	CTD	PMID:29391264
Pask	Rat	epoxiconazole	increases expression	ISO	Pask (Mus musculus)	6480464	epoxiconazole results in increased expression of PASK mRNA	CTD	PMID:35436446
Pask	Rat	fenvalerate	increases expression	EXP		6480464	fenvalerate results in increased expression of PASK mRNA	CTD	PMID:30307764
Pask	Rat	folic acid	multiple interactions	ISO	Pask (Mus musculus)	6480464	[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of PASK mRNA	CTD	PMID:20938992
Pask	Rat	FR900359	decreases phosphorylation	ISO	PASK (Homo sapiens)	6480464	FR900359 results in decreased phosphorylation of PASK protein	CTD	PMID:37730182
Pask	Rat	furan	increases expression	EXP		6480464	furan results in increased expression of PASK mRNA	CTD	PMID:25539665
Pask	Rat	L-methionine	multiple interactions	ISO	Pask (Mus musculus)	6480464	[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of PASK mRNA	CTD	PMID:20938992
Pask	Rat	manganese atom	multiple interactions	ISO	PASK (Homo sapiens)	6480464	[manganese chloride results in increased abundance of Manganese] which results in decreased expression of PASK mRNA	CTD	PMID:39836092
Pask	Rat	manganese(0)	multiple interactions	ISO	PASK (Homo sapiens)	6480464	[manganese chloride results in increased abundance of Manganese] which results in decreased expression of PASK mRNA	CTD	PMID:39836092
Pask	Rat	manganese(II) chloride	multiple interactions	ISO	PASK (Homo sapiens)	6480464	[manganese chloride results in increased abundance of Manganese] which results in decreased expression of PASK mRNA	CTD	PMID:39836092
Pask	Rat	methimazole	increases expression	EXP		6480464	Methimazole results in increased expression of PASK mRNA	CTD	PMID:22504374
Pask	Rat	methoxychlor	increases methylation	EXP		6480464	Methoxychlor results in increased methylation of PASK gene	CTD	PMID:23303685
Pask	Rat	N-methyl-4-phenylpyridinium	increases expression	EXP		6480464	1-Methyl-4-phenylpyridinium results in increased expression of PASK mRNA	CTD	PMID:28801915
Pask	Rat	N-nitrosodiethylamine	multiple interactions	ISO	Pask (Mus musculus)	6480464	[Piperonyl Butoxide co-treated with Diethylnitrosamine] affects the methylation of PASK gene	CTD	PMID:23968726
Pask	Rat	naphthalene	increases expression	ISO	Pask (Mus musculus)	6480464	naphthalene results in increased expression of PASK mRNA	CTD	PMID:18978301
Pask	Rat	nickel atom	increases expression	ISO	PASK (Homo sapiens)	6480464	Nickel results in increased expression of PASK mRNA	CTD	PMID:25583101
Pask	Rat	nitrofen	decreases expression	EXP		6480464	nitrofen results in decreased expression of PASK mRNA	CTD	PMID:33484710
Pask	Rat	oxaliplatin	multiple interactions	EXP		6480464	[oxaliplatin co-treated with Topotecan] results in decreased expression of PASK mRNA	CTD	PMID:25729387
Pask	Rat	ozone	multiple interactions	ISO	Pask (Mus musculus)	6480464	[Air Pollutants results in increased abundance of [Ozone co-treated with Soot]] which results in increased expression of PASK mRNA and [Air Pollutants results in increased abundance of Ozone] which results in increased expression of PASK mRNA	CTD	PMID:34911549
Pask	Rat	ozone	increases expression	ISO	Pask (Mus musculus)	6480464	Ozone results in increased expression of PASK mRNA	CTD	PMID:33026818
Pask	Rat	paracetamol	increases expression	ISO	PASK (Homo sapiens)	6480464	Acetaminophen results in increased expression of PASK mRNA	CTD	PMID:22230336
Pask	Rat	paracetamol	increases expression	EXP		6480464	Acetaminophen results in increased expression of PASK mRNA	CTD	PMID:33387578
Pask	Rat	paracetamol	decreases expression	ISO	PASK (Homo sapiens)	6480464	Acetaminophen results in decreased expression of PASK mRNA	CTD	PMID:29067470
Pask	Rat	PCB138	multiple interactions	ISO	Pask (Mus musculus)	6480464	[2 more ...	CTD	PMID:25510870
Pask	Rat	phenobarbital	affects expression	ISO	Pask (Mus musculus)	6480464	Phenobarbital affects the expression of PASK mRNA	CTD	PMID:19136022
Pask	Rat	phenylmercury acetate	decreases expression	ISO	PASK (Homo sapiens)	6480464	Phenylmercuric Acetate results in decreased expression of PASK mRNA	CTD	PMID:26272509
Pask	Rat	phenylmercury acetate	multiple interactions	ISO	PASK (Homo sapiens)	6480464	[NOG protein co-treated with Phenylmercuric Acetate co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of PASK mRNA	CTD	PMID:27188386
Pask	Rat	piperonyl butoxide	multiple interactions	ISO	Pask (Mus musculus)	6480464	[Piperonyl Butoxide co-treated with Diethylnitrosamine] affects the methylation of PASK gene	CTD	PMID:23968726
Pask	Rat	pirinixic acid	affects expression	ISO	Pask (Mus musculus)	6480464	pirinixic acid affects the expression of PASK mRNA	CTD	PMID:19136022
Pask	Rat	quercetin	decreases expression	ISO	PASK (Homo sapiens)	6480464	Quercetin results in decreased expression of PASK mRNA	CTD	PMID:21632981
Pask	Rat	SB 431542	multiple interactions	ISO	PASK (Homo sapiens)	6480464	[NOG protein co-treated with Phenylmercuric Acetate co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of PASK mRNA	CTD	PMID:27188386
Pask	Rat	sodium arsenite	increases expression	ISO	PASK (Homo sapiens)	6480464	sodium arsenite results in increased expression of PASK mRNA	CTD	PMID:28595984 and PMID:34032870
Pask	Rat	sodium arsenite	multiple interactions	ISO	PASK (Homo sapiens)	6480464	[sodium arsenite results in increased abundance of Arsenic] which results in decreased expression of PASK mRNA	CTD	PMID:39836092
Pask	Rat	sodium arsenite	decreases expression	ISO	PASK (Homo sapiens)	6480464	sodium arsenite results in decreased expression of PASK mRNA	CTD	PMID:38568856
Pask	Rat	sodium dodecyl sulfate	decreases expression	EXP		6480464	Sodium Dodecyl Sulfate results in decreased expression of PASK mRNA	CTD	PMID:12815608
Pask	Rat	sodium fluoride	increases expression	ISO	Pask (Mus musculus)	6480464	Sodium Fluoride results in increased expression of PASK protein	CTD	PMID:28918527
Pask	Rat	sunitinib	decreases expression	ISO	PASK (Homo sapiens)	6480464	Sunitinib results in decreased expression of PASK mRNA	CTD	PMID:31533062
Pask	Rat	tert-butyl hydroperoxide	decreases expression	ISO	PASK (Homo sapiens)	6480464	tert-Butylhydroperoxide results in decreased expression of PASK mRNA	CTD	PMID:15336504
Pask	Rat	thioacetamide	increases expression	EXP		6480464	Thioacetamide results in increased expression of PASK mRNA	CTD	PMID:34492290
Pask	Rat	titanium dioxide	increases expression	ISO	Pask (Mus musculus)	6480464	titanium dioxide results in increased expression of PASK mRNA	CTD	PMID:23557971
Pask	Rat	titanium dioxide	decreases methylation	ISO	Pask (Mus musculus)	6480464	titanium dioxide results in decreased methylation of PASK gene and titanium dioxide results in decreased methylation of PASK promoter alternative form	CTD	PMID:35295148
Pask	Rat	topotecan	decreases expression	EXP		6480464	Topotecan results in decreased expression of PASK mRNA	CTD	PMID:25729387
Pask	Rat	topotecan	multiple interactions	EXP		6480464	[oxaliplatin co-treated with Topotecan] results in decreased expression of PASK mRNA	CTD	PMID:25729387
Pask	Rat	trimellitic anhydride	increases expression	ISO	Pask (Mus musculus)	6480464	trimellitic anhydride results in increased expression of PASK mRNA	CTD	PMID:19042947
Pask	Rat	troglitazone	decreases expression	ISO	PASK (Homo sapiens)	6480464	troglitazone results in decreased expression of PASK mRNA	CTD	PMID:19140230
Pask	Rat	trovafloxacin	decreases expression	ISO	Pask (Mus musculus)	6480464	trovafloxacin results in decreased expression of PASK mRNA	CTD	PMID:35537566

Biological Process

Only show annotations with direct experimental evidence (0 objects hidden)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
Pask	Rat	energy homeostasis	involved_in	ISO	Pask (Mus musculus)	1624291	PMID:17878307	RGD	PMID:17878307
Pask	Rat	intracellular signal transduction	involved_in	IBA	PANTHER:PTN002519176 more ...	1600115	GO_REF:0000033	GO_Central	GO_REF:0000033
Pask	Rat	negative regulation of glycogen biosynthetic process	involved_in	ISO	PASK (Homo sapiens)	1624291	PMID:16275910	RGD	PMID:16275910
Pask	Rat	negative regulation of glycogen biosynthetic process	involved_in	IBA	PANTHER:PTN000540439 more ...	1600115	GO_REF:0000033	GO_Central	GO_REF:0000033
Pask	Rat	protein autophosphorylation	involved_in	ISO	PASK (Homo sapiens)	1624291	PMID:20943661 and PMID:21418524	RGD	PMID:20943661 and PMID:21418524
Pask	Rat	protein phosphorylation	involved_in	ISO	PASK (Homo sapiens)	1624291	PMID:16275910	RGD	PMID:16275910
Pask	Rat	regulation of glucagon secretion	involved_in	ISO	Pask (Mus musculus)	1624291	PMID:21181396	RGD	PMID:21181396
Pask	Rat	regulation of respiratory gaseous exchange	involved_in	ISO	Pask (Mus musculus)	1624291	PMID:18509100	RGD	PMID:18509100

Cellular Component

Only show annotations with direct experimental evidence (0 objects hidden)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
Pask	Rat	cytoplasm	located_in	ISO	PASK (Homo sapiens)	1624291	PMID:17595531	RGD	PMID:17595531
Pask	Rat	cytoplasm	is_active_in	IBA	FB:FBgn0038167 more ...	1600115	GO_REF:0000033	GO_Central	GO_REF:0000033
Pask	Rat	cytosol	located_in	ISO	PASK (Homo sapiens) more ...	1624291		RGD	GO_REF:0000052
Pask	Rat	cytosol	is_active_in	IBA	PANTHER:PTN000540439 and UniProtKB:Q96RG2	1600115	GO_REF:0000033	GO_Central	GO_REF:0000033
Pask	Rat	nucleus	located_in	ISO	PASK (Homo sapiens)	1624291	PMID:17595531	RGD	PMID:17595531
Pask	Rat	nucleus	is_active_in	IBA	PANTHER:PTN000540439 and UniProtKB:Q96RG2	1600115	GO_REF:0000033	GO_Central	GO_REF:0000033

Molecular Function

Only show annotations with direct experimental evidence (0 objects hidden)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
Pask	Rat	ATP binding	enables	IEA	UniRule:UR001503341	1600115	GO_REF:0000104	UniProt	GO_REF:0000104
Pask	Rat	ATP binding	enables	IEA	InterPro:IPR000719 and InterPro:IPR017441	1600115	GO_REF:0000002	InterPro	GO_REF:0000002
Pask	Rat	ATP binding	enables	IEA	UniProtKB-KW:KW-0067	1600115	GO_REF:0000043	UniProt	GO_REF:0000043
Pask	Rat	kinase activity	enables	IEA	UniProtKB-KW:KW-0418	1600115	GO_REF:0000043	UniProt	GO_REF:0000043
Pask	Rat	nucleotide binding	enables	IEA	UniProtKB-KW:KW-0547	1600115	GO_REF:0000043	UniProt	GO_REF:0000043
Pask	Rat	nucleotide binding	enables	IEA	UniRule:UR001503341	1600115	GO_REF:0000104	UniProt	GO_REF:0000104
Pask	Rat	phosphatidylinositol binding	enables	ISO	PASK (Homo sapiens)	1624291	PMID:21418524	RGD	PMID:21418524
Pask	Rat	protein binding	enables	ISO	PASK (Homo sapiens)	1624291	UniProtKB:P02542 more ...	RGD	PMID:16275910 more ...
Pask	Rat	protein kinase activity	enables	IEA	InterPro:IPR000719 and InterPro:IPR008271	1600115	GO_REF:0000002	InterPro	GO_REF:0000002
Pask	Rat	protein serine/threonine kinase activity	enables	ISO	PASK (Homo sapiens)	1624291	PMID:16275910 more ...	RGD	PMID:16275910 more ...
Pask	Rat	protein serine/threonine kinase activity	enables	IEA	UniProtKB-KW:KW-0723	1600115	GO_REF:0000043	UniProt	GO_REF:0000043
Pask	Rat	protein serine/threonine kinase activity	enables	IBA	CGD:CAL0000201729 more ...	1600115	GO_REF:0000033	GO_Central	GO_REF:0000033

#	Reference Title	Reference Citation
1.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2.	Rat ISS GO annotations from MGI mouse gene data--August 2006	MGD data from the GO Consortium
3.	GOA pipeline	RGD automated data pipeline
4.	ClinVar Automated Import and Annotation Pipeline	RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
5.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions

PMID:12477932	PMID:16275910	PMID:17595531	PMID:17878307	PMID:18509100	PMID:19502418	PMID:20943661	PMID:21181396	PMID:21418524	PMID:22065581	PMID:23765195	PMID:23853095
PMID:25515571	PMID:26003800

Pask
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	9	101,291,673 - 101,333,288 (-)	NCBI		GRCr8
mRatBN7.2	9	93,844,275 - 93,886,036 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	9	93,844,278 - 93,885,111 (-)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	9	102,279,835 - 102,320,665 (-)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	9	107,415,644 - 107,456,467 (-)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	9	105,771,786 - 105,812,609 (-)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	9	100,450,595 - 100,479,719 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	9	100,450,586 - 100,479,868 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	9	100,106,950 - 100,136,074 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	9	92,582,177 - 92,623,004 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	9	92,786,946 - 92,827,773 (-)	NCBI
Celera	9	91,379,229 - 91,420,042 (-)	NCBI		Celera
Cytogenetic Map	9	q36	NCBI

PASK
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	2	241,106,099 - 241,150,347 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	2	241,106,099 - 241,150,264 (-)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	2	242,045,514 - 242,089,637 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	2	241,694,188 - 241,737,551 (-)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	2	241,765,504 - 241,808,868	NCBI
Celera	2	235,715,217 - 235,758,602 (-)	NCBI		Celera
Cytogenetic Map	2	q37.3	NCBI
HuRef	2	233,801,521 - 233,845,836 (-)	NCBI		HuRef
CHM1_1	2	242,051,569 - 242,095,450 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	2	241,605,207 - 241,649,447 (-)	NCBI		T2T-CHM13v2.0

Pask
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	1	93,237,165 - 93,271,237 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	1	93,236,492 - 93,271,204 (-)	Ensembl		GRCm39 Ensembl
GRCm38	1	93,309,437 - 93,343,522 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	1	93,308,770 - 93,343,482 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	1	95,206,014 - 95,239,365 (-)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	1	95,139,843 - 95,167,980 (-)	NCBI		MGSCv36	mm8
Celera	1	96,254,103 - 96,287,403 (-)	NCBI		Celera
Cytogenetic Map	1	D	NCBI
cM Map	1	47.24	NCBI

Pask
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955542	555,030 - 578,227 (+)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955542	539,806 - 578,496 (+)	NCBI	ChiLan1.0	ChiLan1.0

PASK
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	13	143,795,782 - 143,850,798 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	2B	143,810,747 - 143,865,694 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	2B	128,364,745 - 128,418,837 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	2B	247,162,011 - 247,215,451 (-)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	2B	247,162,011 - 247,214,803 (-)	Ensembl	panpan1.1		panPan2

PASK
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	25	51,145,094 - 51,181,040 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	25	51,144,912 - 51,177,818 (-)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	25	51,358,398 - 51,393,714 (-)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	25	51,340,211 - 51,375,472 (-)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	25	51,338,043 - 51,375,448 (-)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	25	51,187,899 - 51,223,198 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	25	50,927,406 - 50,962,618 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	25	51,203,734 - 51,238,468 (-)	NCBI		UU_Cfam_GSD_1.0

Pask
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024405303	192,515,388 - 192,555,345 (-)	NCBI		HiC_Itri_2
SpeTri2.0	NW_004936745	664,062 - 704,027 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

PASK
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	15	139,890,178 - 139,917,069 (-)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	15	139,887,439 - 139,917,887 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	15	155,006,110 - 155,031,416 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

PASK
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	10	127,156,577 - 127,206,745 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	10	127,156,558 - 127,199,845 (-)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666040	72,175,714 - 72,226,448 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Pask
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624847	5,216,441 - 5,238,908 (-)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624847	5,215,626 - 5,246,540 (-)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Variants in Pask
115 total Variants

Assembly: mRatBN7.2

Chromosome	Start Pos	End Pos	Reference Nucleotide	Variant Nucleotide	Variant Type	Strain	Variant Page
9	93879085	93879086	G	A	snv	European Variation Archive Release 3, European Variation Archive Release 4, European Variation Archive Release 6, DA/OlaHsd (2019NG), ACI/N (2020), DA/OlaHsd (2019), ACI/EurMcwi (2019NG), ACI/EurMcwi (2019)	View more Information

Predicted Target Of

	Summary Value
Count of predictions:	39
Count of miRNA genes:	35
Interacting mature miRNAs:	37
Transcripts:	ENSRNOT00000022748
Prediction methods:	Miranda, Rnahybrid
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
1582203	Gluco19	Glucose level QTL 19	3.3	0.001	blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	9	92491589	100929786	Rat
724515	Uae16	Urinary albumin excretion QTL 16	8		urine albumin amount (VT:0002871)	urine albumin excretion rate (CMO:0000757)	9	58163035	100929646	Rat
731171	Glom6	Glomerulus QTL 6	2.8	0.0003	kidney glomerulus morphology trait (VT:0005325)	count of superficial glomeruli not directly contacting the kidney surface (CMO:0001002)	9	64573531	109573531	Rat
724547	Cm21	Cardiac mass QTL 21	2.7		heart mass (VT:0007028)	calculated heart weight (CMO:0000073)	9	79271511	102910209	Rat
61385	Edpm9	Estrogen-dependent pituitary mass QTL 9	3.43	0.05	pituitary gland mass (VT:0010496)	pituitary gland wet weight (CMO:0000853)	9	63869687	108869687	Rat
724544	Uae9	Urinary albumin excretion QTL 9	4.5		urine albumin amount (VT:0002871)	urine albumin level (CMO:0000130)	9	25268044	114175309	Rat
2290450	Scl57	Serum cholesterol level QTL 57	4.15		blood cholesterol amount (VT:0000180)	plasma total cholesterol level (CMO:0000585)	9	36962359	95410867	Rat
1578760	Cm53	Cardiac mass QTL 53	3.3	0.0001	heart mass (VT:0007028)	heart wet weight (CMO:0000069)	9	56771635	101771635	Rat
1581580	Uae34	Urinary albumin excretion QTL 34			urine albumin amount (VT:0002871)	urine albumin excretion rate (CMO:0000757)	9	62072275	96470995	Rat
1300134	Bp185	Blood pressure QTL 185	3.73		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	9	61381434	104821652	Rat
1354626	Bvd1	Brain ventricular dilatation QTL 1	3.73	0.001	brain ventricle morphology trait (VT:0000822)	hydrocephalus severity score (CMO:0001881)	9	75712843	111552878	Rat
4889852	Pur26	Proteinuria QTL 26	15	0.001	urine total protein amount (VT:0000032)	urine total protein excretion rate (CMO:0000756)	9	77813894	101597663	Rat
7794784	Mcs31	Mammary carcinoma susceptibility QTL 31	2.98		mammary gland integrity trait (VT:0010552)	mammary tumor incidence/prevalence measurement (CMO:0000946)	9	77813894	111552878	Rat
731164	Uae25	Urinary albumin excretion QTL 25	3.5	0.0001	urine albumin amount (VT:0002871)	urine albumin excretion rate (CMO:0000757)	9	25661188	100929786	Rat
1578757	Pur6	Proteinuria QTL 6	3.3	0.005	urine total protein amount (VT:0000032)	urine total protein excretion rate (CMO:0000756)	9	62072275	96470995	Rat

BG379473

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	9	93,844,433 - 93,844,525 (+)	MAPPER	mRatBN7.2
Rnor_6.0	9	100,450,754 - 100,450,845	NCBI	Rnor6.0
Rnor_5.0	9	100,107,109 - 100,107,200	UniSTS	Rnor5.0
RGSC_v3.4	9	92,582,336 - 92,582,427	UniSTS	RGSC3.4
Celera	9	91,379,388 - 91,379,479	UniSTS
RH 3.4 Map	9	815.3	UniSTS
Cytogenetic Map	9	q36	UniSTS

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

alimentary part of gastrointestinal system	appendage	circulatory system	ectoderm	endocrine system	endoderm	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	mesenchyme	mesoderm	nervous system	renal system	reproductive system	respiratory system
9	11	49	113	91	90	59	25	59	6	218	97	93	45	60	31


RefSeq Transcripts	NM_001009362	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	NM_001432217	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	NM_001432218	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	NM_001432219	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	NM_001432220	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039083419	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039083420	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039083422	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063267041	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	BC087047	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH473997	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000009	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSRNOT00000022748 ⟹ ENSRNOP00000022748

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	9	93,844,278 - 93,885,111 (-)	Ensembl
Rnor_6.0 Ensembl	9	100,450,586 - 100,479,868 (-)	Ensembl

Ensembl Acc Id:

ENSRNOT00000095651 ⟹ ENSRNOP00000087231

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	9	93,844,278 - 93,885,111 (-)	Ensembl

RefSeq Acc Id:

NM_001009362 ⟹ NP_001009362

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	9	101,291,673 - 101,332,504 (-)	NCBI
mRatBN7.2	9	93,844,275 - 93,885,111 (-)	NCBI
Rnor_6.0	9	100,450,595 - 100,479,719 (-)	NCBI
Rnor_5.0	9	100,106,950 - 100,136,074 (-)	NCBI
RGSC_v3.4	9	92,582,177 - 92,623,004 (-)	RGD
Celera	9	91,379,229 - 91,420,042 (-)	RGD

Sequence:

show sequence

CGTTTGACCCGCGCTCAGGAGCCGCCAGCGCCCGAAAGTCTCTGACTGAACTGGAAGCTTTGCTTTAAGGTGAGGGCTGTTGGAAGCAAGAGCTTGGTGACCAGTTGCTCTGCTCTTCATGGAGGACA
GAGGTCCACCAGTTCTTGCTGAGGACTGGAAGTCTGAGAGTCTTCCTGCCCAAGAGGGCCCAGCTACCCAGGCTTTCGTTGAGCCCAGCAAGCCTCTCTCCATAGCCCATAGACACCTGAACAGGAAG
AATGGGCTTTCTAGACTCTGCCAGAGCCGAATGGCACTCTCCGAGGATAGGTGGAGCTCTTACTGTCTTTCATCATTGGCTGCCCAAAACATCTGCACAAGCAAACTGCACTGCGCTGCTACACCTGA
CTATGCTGACCCTATAGCTGGCCCACTGGGCAGTACATCGTGCTGCTCCTTGCTACGTGGCCTAGCTTCAGGGTGCTCTGGACCTCTGCTCTCGACCCCTGTGTGCAACCCTAACAAGGCTGTCTTTA
CTGTGGATGCCAAGACCACAGAGATTCTGGTTGCCAATGACAAAGCCTGCAGCCTCCTGGGGTATAGCAGTCATGACCTGATTGGCCAAAAGCTTACACAGTTCTTCCTCAAGTCTGATTCCGAGGTT
GTGGAAGCCCTCAGCGAGGAGCATGTGGAGGCTGATGGCCACGCTGCAGTAGTGTTCGGCACGGTGGTGGACATTGTCAGCCGAAGTGGGGAGAAGATTCCCGTCTCTGTGTGGATAAAGAGGTTGCA
ACAAGATCGTGGCTTGTGCTGTGTAGTGGTTCTGGAGCCTGTGGAGAGGGTCTCAGCCTGGGTCGCCTTCCAGAGTGATGGAACTATCACGTCATGCGACAGCCTCTTTGCTCATCTTCATGGGTTCA
CATCTCCAAAGGATGTGGTTGGGCAGTGTGTCATAGACTTGATTCCATCTATACAGCTCCCTCCTCCTGGCCAACATGTCCCAAAGAGTCTCAAGATTCAAAGGTCTGTTGGGAGAGCCAGAGACGGG
ACCACCTTCCCTCTCAGTCTGAAGTTGAAATCTAAGACCAGTGGAAAGGCTGTAGCTGAAAGTGAGGTGGCCTCAGAACCAGGTTACCAGGCTTCTGTGTGGGTGTTCTGCACCATCAGTGGCCTCAT
CACTCTCCTGCCTGATGGCACAATTTATGGCATCAACCACAGCTTTGCACTAATGTTGTTTGGTTATGGAAAAACAGAGCTCCTGGGCAAGAACATCACTTGCCTGATTCCTGGTTTCTACCACTGCA
TGGACCTTGCATATGATAGTTCTGTCCAGCTGCCAGATCTGGTCAACTGCCTGGACATTGGCAGCAAGAGTGGGCCTGGGGAGATGAGTTCTGATGCCAAGCAGGACTGGGAGCTGGCCAGTGGGGCC
CAAGATCCAAGAATTGATGTGTTGACACGGGGCCACATGCCATCACAAGATGAGACCCTGAAGCTGCGGGGAGGACAAGTCTCGCCTAGGACTCAGACTCAGCTGGAAACTGGACGCCACATACTTCC
TTCTTGTGCATCTCAGCCCTCCCTGGGGGTAGACAGCAGCCCAGTGGACGGTGAGCGGTCATTACCCACAGACCAGCGGAACGTTCCAAAGAGAAACCTGCTAGCCCATGCTGAACAGTTACTATCTC
AGACCCAACCAGACACCCTGGAAATATCCCCACCAGTCCTTAAAGAACTGTCTGAAATTCAGAAAAATATCTCAGAAGAAAGCCCACTAACCCACAGGAAATGGTTATTGTCCAAGGCCCAGAAAGAC
ACCACAAAAGGAAGCCTGCCAATCCATGATGAGAAGTTACTGCTTGCAAGCCAGCATATCCATGTCTTGGGAAAGGAAAATCCTTCAGCAGCAGAGAGCTACAGGGAGGGTCTTTTAGCAGAAAGCAG
GTCCAAACCAGTGGATGCAAAACCGTTTGCTTCATGTGAAGATTCTGAGCTTCTAGTCCCAGCTAAGGACAGAAGCAACAGAGCGGACATGAGTAGTCTGCAACAGGAAGCTCAATTGGAGCTGATGG
GTATCAGTAGTCCCGGTAGTCCTAACCCCTGGGCTGATGCCACCATGCCTGAGCCCCACACCACAGGGCAGATACCAGGAGGGAGCCTGACATACTGCCCACAGCATAGAAGCGAGTGGATCTTACAA
CAGCGAGGCCAGGACTCGGCTCCCAGCCCCTCTGCAATGGGGTGTGTCTTTGTTGGGACACCCACTCTGGATGAACCATGGCCAGGAGTGAGAAATGATCGAGAAGAGCTGCAGACTTGCTTGATTAA
GGAACAGTTGTCCAAGTCAAGCTTTGGGGGAGCTCTAGGAATCTCCTGTGTGGAACTTGTCCCAGCAGAACATCCTCCTTTCACTGCCCCCGTGTCCTTCTGTGATTGGGGAGGCCGAGACCTACATG
CTAGCCGCTCAGGCAGCTCCTCAGCCTGCTATGCTTTGGCCACTGACCTCCCTGGTGTCTTGGAGGCAGTGGAAGCCCAGGAGGCTGATGTGAGTTCTTATTCCTGGAACCTCAGGGAGCTCTTTCTC
AATGACCGGACAGACAGAACTCCATCACATTGTTCCTGTACCACTTCTGAACTTAGCGAGACACCATCTCTTTCAGGGGTGGGGTCAGATTTAGATGTGGGTATTCTGCACAGGCAGACTTCAGATAT
TTTAGCTCACCGAGAGATGTTGCTTCTTAGTGGGACCTATTTTGACCTTAGGGAAGGCCATCGGTTCCAGGAGATGGGAGCAGGACATGATGGAGCAGAACTGTCTAACATTTCTTTGGTATCCTCTG
AACACTATGAAACTAGTGACATAGAAAGCCTAGGTTGTGACCCTCCCATACCAGATCCTGGTCCTAACAATATGTGCCTATCAGCAGAGAAGCCTAGACTGAGTGCCCAGATCACTTCCACTCCTGTG
GCACCTGGGCCCACCAGCCTGCAGCAGGAGATCCAGGAGGGCATCTTCTCTGGAAGCTGCTACCACCGAGATGGCTTACGACTGAGTGTACAGTTTGAAGTAAAGCGTGTGCAGCTCCAGGGCTCTGC
AACCCTGTTCTGCTGCTGGCTGGTGAAGGACTTCTTACACAGTCACCGGGACTCAGCCACCCGAACCCGCCTGTTCCTTGCCAGCCTGCCAAGCTCTACCCACTCCATGCCTGACCTCTCTGGATCCA
GCTTTGGAGAGATGCTCAGAGCCAAGCCTTGGTTTGAGGAGTCCCCAACACCCGCAGAGCTGGAGGGGCTGGCAGCCTGTGAGGGCGAGTACTCCCATAAGTACAACACCCTGCGCCCACTCGGCAGT
GGCGCCTTTGGCTTTGTGTGGACTGCAGTGGAGAAGGAAGGCAACAAAGAGGTGGTGGTGAAGTTTATTAAGAAGGAGAAGGTTTTAGAGGATTGTTGGGTTGAAGATCCCAAACTTGGAAGAGTTCC
TTTAGAGATTTCAATTCTGTCCAAGGTGGAACATGCCAACATAATCAAGATTGTGGATGTATTCGAAAACCAAGGGTTCTTTCAGCTAGTGATGGAAAAGCATGGCTCTGGCTTGGACCTCTTTGCTT
TCATTGACCGTCATCCCTGCTTGGATGAGCCCCTGGCGAGTTACATCTTCCGACAACTGGTGTCTGCTGTAAGATACTTGCGTTCCCAAGGCATCATCCATAGAGACATCAAGGATGAGAACATTGTG
ATTGCTGAGGACTTCACAATTAAGCTGATAGATTTTGGCTCAGCTGCCTACTTAGAGAAGGGCAAACTATTTTATACCTTTTGTGGAACAATTGAATACTGTGCACCTGAAGTTCTCATTGGAAATCC
CTACAGAGGGCCAGAGCTGGAGATGTGGTCTCTCGGGGTCACGCTGTACACGCTCATCTTCGAGGAGAATCCCTTCTGTGAGGTGGAGGAGACCATGGAGGCAGTTATTCATCCCCCCTTCCTGGTTT
CCCAAGAACTTATGAGTCTTCTGTCTGGGCTGCTGCAGCCTTGCCCTGAGCAGCGGACCACTTTGGAGAAGCTGATTGTGGACCCCTGGGTGACACAGCCTGTGAACCTTGATAACTACACCTGGGAA
GAGGTGTGTCGGACCAGCCAGCCAGAAAGTGGCCTGATGTCAGCTGCAAGTCTGGAGCTTGCGAGTAGGAGTCCAAGTGAAGTGGCTCAGACAGAGGGTCTTTGTAGACCTCCTGCTCCCAAGGAGGC
TCCTGGTAACCACTGCTTGCATCTTGAGGATCCCTCGTCACCAGTCAGCTGAGCAAGTGCTCCTCTTCTCCACATGGTTTGGGGAATTGTATGGATTTTAGGGCTTCCACTGGAGAAAGGAGTTGTGA
AGAATCGGCATGAATCCCTCTATAGATTCCTGTGCGAATCTACAAGAGCCTGCGGTACTATTTTTCTTAGGTTTGTGATACAGACTTGTAACATGTTATTTTTTATAACCTTGAAAATCATTCTAATG
TTCGATTACATTGTACTATTAAAGGGCTTTAAGTTGTGAGCCTCAGAAAGACAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA

hide sequence

RefSeq Acc Id:

XM_039083419 ⟹ XP_038939347

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	9	101,291,673 - 101,332,773 (-)	NCBI
mRatBN7.2	9	93,844,275 - 93,886,036 (-)	NCBI

RefSeq Acc Id:

XM_039083420 ⟹ XP_038939348

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	9	101,291,673 - 101,333,288 (-)	NCBI
mRatBN7.2	9	93,844,275 - 93,886,036 (-)	NCBI

RefSeq Acc Id:

XM_039083422 ⟹ XP_038939350

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	9	101,291,673 - 101,332,773 (-)	NCBI
mRatBN7.2	9	93,844,275 - 93,886,036 (-)	NCBI

RefSeq Acc Id:

XM_063267041 ⟹ XP_063123111

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	9	101,291,673 - 101,332,626 (-)	NCBI


Protein RefSeqs	NP_001009362	(Get FASTA)	NCBI Sequence Viewer
	NP_001419146	(Get FASTA)	NCBI Sequence Viewer
	NP_001419147	(Get FASTA)	NCBI Sequence Viewer
	NP_001419148	(Get FASTA)	NCBI Sequence Viewer
	NP_001419149	(Get FASTA)	NCBI Sequence Viewer
	XP_038939347	(Get FASTA)	NCBI Sequence Viewer
	XP_038939348	(Get FASTA)	NCBI Sequence Viewer
	XP_038939350	(Get FASTA)	NCBI Sequence Viewer
	XP_063123111	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAH87047	(Get FASTA)	NCBI Sequence Viewer
	EDL91952	(Get FASTA)	NCBI Sequence Viewer
	EDL91953	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000022748
	ENSRNOP00000022748.3
	ENSRNOP00000087231
	ENSRNOP00000087231.1

RefSeq Acc Id:

NP_001009362 ⟸ NM_001009362

- UniProtKB:

Q5PQT0 (UniProtKB/TrEMBL), F7F091 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MEDRGPPVLAEDWKSESLPAQEGPATQAFVEPSKPLSIAHRHLNRKNGLSRLCQSRMALSEDRWSSYCLSSLAAQNICTSKLHCAATPDYADPIAGPLGSTSCCSLLRGLASGCSGPLLSTPVCNPNK
AVFTVDAKTTEILVANDKACSLLGYSSHDLIGQKLTQFFLKSDSEVVEALSEEHVEADGHAAVVFGTVVDIVSRSGEKIPVSVWIKRLQQDRGLCCVVVLEPVERVSAWVAFQSDGTITSCDSLFAHL
HGFTSPKDVVGQCVIDLIPSIQLPPPGQHVPKSLKIQRSVGRARDGTTFPLSLKLKSKTSGKAVAESEVASEPGYQASVWVFCTISGLITLLPDGTIYGINHSFALMLFGYGKTELLGKNITCLIPGF
YHCMDLAYDSSVQLPDLVNCLDIGSKSGPGEMSSDAKQDWELASGAQDPRIDVLTRGHMPSQDETLKLRGGQVSPRTQTQLETGRHILPSCASQPSLGVDSSPVDGERSLPTDQRNVPKRNLLAHAEQ
LLSQTQPDTLEISPPVLKELSEIQKNISEESPLTHRKWLLSKAQKDTTKGSLPIHDEKLLLASQHIHVLGKENPSAAESYREGLLAESRSKPVDAKPFASCEDSELLVPAKDRSNRADMSSLQQEAQL
ELMGISSPGSPNPWADATMPEPHTTGQIPGGSLTYCPQHRSEWILQQRGQDSAPSPSAMGCVFVGTPTLDEPWPGVRNDREELQTCLIKEQLSKSSFGGALGISCVELVPAEHPPFTAPVSFCDWGGR
DLHASRSGSSSACYALATDLPGVLEAVEAQEADVSSYSWNLRELFLNDRTDRTPSHCSCTTSELSETPSLSGVGSDLDVGILHRQTSDILAHREMLLLSGTYFDLREGHRFQEMGAGHDGAELSNISL
VSSEHYETSDIESLGCDPPIPDPGPNNMCLSAEKPRLSAQITSTPVAPGPTSLQQEIQEGIFSGSCYHRDGLRLSVQFEVKRVQLQGSATLFCCWLVKDFLHSHRDSATRTRLFLASLPSSTHSMPDL
SGSSFGEMLRAKPWFEESPTPAELEGLAACEGEYSHKYNTLRPLGSGAFGFVWTAVEKEGNKEVVVKFIKKEKVLEDCWVEDPKLGRVPLEISILSKVEHANIIKIVDVFENQGFFQLVMEKHGSGLD
LFAFIDRHPCLDEPLASYIFRQLVSAVRYLRSQGIIHRDIKDENIVIAEDFTIKLIDFGSAAYLEKGKLFYTFCGTIEYCAPEVLIGNPYRGPELEMWSLGVTLYTLIFEENPFCEVEETMEAVIHPP
FLVSQELMSLLSGLLQPCPEQRTTLEKLIVDPWVTQPVNLDNYTWEEVCRTSQPESGLMSAASLELASRSPSEVAQTEGLCRPPAPKEAPGNHCLHLEDPSSPVS

hide sequence

Ensembl Acc Id:

ENSRNOP00000022748 ⟸ ENSRNOT00000022748

RefSeq Acc Id:	XP_038939348 ⟸ XM_039083420
- Peptide Label:	isoform X1
- UniProtKB:	Q5PQT0 (UniProtKB/TrEMBL), F7F091 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_038939350 ⟸ XM_039083422
- Peptide Label:	isoform X2

RefSeq Acc Id:	XP_038939347 ⟸ XM_039083419
- Peptide Label:	isoform X1

Protein Domains

PAS Protein kinase

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-Q5PQT0-F1-model_v2	AlphaFold	Q5PQT0	1-1385	view protein structure

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Database	Acc Id	Source(s)
BioCyc Gene	G2FUF-26649	BioCyc
Ensembl Genes	ENSRNOG00000016888	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSRNOT00000022748	ENTREZGENE
	ENSRNOT00000022748.7	UniProtKB/TrEMBL
	ENSRNOT00000095651	ENTREZGENE
	ENSRNOT00000095651.1	UniProtKB/TrEMBL
Gene3D-CATH	PAS domain	UniProtKB/TrEMBL
	Phosphorylase Kinase, domain 1	UniProtKB/TrEMBL
	Transferase(Phosphotransferase) domain 1	UniProtKB/TrEMBL
IMAGE_CLONE	IMAGE:7112450	IMAGE-MGC_LOAD
InterPro	Kinase-like_dom	UniProtKB/TrEMBL
	PAS	UniProtKB/TrEMBL
	PAS-like_dom_sf	UniProtKB/TrEMBL
	Prot_kinase_cat_dom	UniProtKB/TrEMBL
	Protein_kinase_ATP_BS	UniProtKB/TrEMBL
	Ser/Thr_prot_kinase_AS	UniProtKB/TrEMBL
KEGG Report	rno:301617	UniProtKB/TrEMBL
MGC_CLONE	MGC:93882	IMAGE-MGC_LOAD
NCBI Gene	301617	ENTREZGENE
PANTHER	MAP/MICROTUBULE AFFINITY-REGULATING KINASE	UniProtKB/TrEMBL
	PAS DOMAIN-CONTAINING SERINE_THREONINE-PROTEIN KINASE	UniProtKB/TrEMBL
Pfam	PAS_9	UniProtKB/TrEMBL
	Pkinase	UniProtKB/TrEMBL
PhenoGen	Pask	PhenoGen
PROSITE	PAS	UniProtKB/TrEMBL
	PROTEIN_KINASE_ATP	UniProtKB/TrEMBL
	PROTEIN_KINASE_DOM	UniProtKB/TrEMBL
	PROTEIN_KINASE_ST	UniProtKB/TrEMBL
RatGTEx	ENSRNOG00000016888	RatGTEx
SMART	PAS	UniProtKB/TrEMBL
	S_TKc	UniProtKB/TrEMBL
Superfamily-SCOP	Kinase_like	UniProtKB/TrEMBL
	SSF55785	UniProtKB/TrEMBL
UniProt	A0A8I6GFT4	ENTREZGENE, UniProtKB/TrEMBL
	F7F091	ENTREZGENE, UniProtKB/TrEMBL
	Q5PQT0	ENTREZGENE, UniProtKB/TrEMBL

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2005-12-06	Pask	PAS domain containing serine/threonine kinase	Pask_predicted	PAS domain containing serine/threonine kinase (predicted)	Symbol and Name updated	1559027	APPROVED
2005-01-12	Pask_predicted	PAS domain containing serine/threonine kinase (predicted)			Symbol and Name status set to approved	70820	APPROVED

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailable


InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailable


Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
		Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable

Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD

Send us a Message

Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD