PASK (PAS domain containing serine/threonine kinase) - Rat Genome Database

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Gene: PASK (PAS domain containing serine/threonine kinase) Pan paniscus
Analyze
Symbol: PASK
Name: PAS domain containing serine/threonine kinase
RGD ID: 11877929
Description: ENCODES a protein that exhibits ATP binding (inferred); phosphatidylinositol binding (inferred); protein kinase activity (inferred); INVOLVED IN energy homeostasis (inferred); intracellular signal transduction (inferred); negative regulation of glycogen biosynthetic process (inferred); ASSOCIATED WITH autistic disorder (ortholog); Bethlem Myopathy 1A (ortholog); chromosome 2q37 deletion syndrome (ortholog); FOUND IN cytoplasm (inferred); cytosol (inferred); nucleus (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: PAS domain-containing serine/threonine-protein kinase
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly
Position:
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v213143,795,782 - 143,850,798 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12B143,810,747 - 143,865,694 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02B128,364,745 - 128,418,837 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12B247,162,011 - 247,215,451 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2B247,162,011 - 247,214,803 (-)Ensemblpanpan1.1panPan2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
cytoplasm  (IEA)
cytosol  (IEA)
nucleus  (IEA)

Molecular Function

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
PASK
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v213143,795,782 - 143,850,798 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12B143,810,747 - 143,865,694 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02B128,364,745 - 128,418,837 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12B247,162,011 - 247,215,451 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2B247,162,011 - 247,214,803 (-)Ensemblpanpan1.1panPan2
PASK
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382241,106,099 - 241,150,347 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2241,106,099 - 241,150,264 (-)EnsemblGRCh38hg38GRCh38
GRCh372242,045,514 - 242,089,637 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 362241,694,188 - 241,737,551 (-)NCBINCBI36Build 36hg18NCBI36
Build 342241,765,504 - 241,808,868NCBI
Celera2235,715,217 - 235,758,602 (-)NCBICelera
Cytogenetic Map2q37.3NCBI
HuRef2233,801,521 - 233,845,836 (-)NCBIHuRef
CHM1_12242,051,569 - 242,095,450 (-)NCBICHM1_1
T2T-CHM13v2.02241,605,207 - 241,649,447 (-)NCBIT2T-CHM13v2.0
Pask
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39193,237,165 - 93,271,237 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl193,236,492 - 93,271,204 (-)EnsemblGRCm39 Ensembl
GRCm38193,309,437 - 93,343,522 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl193,308,770 - 93,343,482 (-)EnsemblGRCm38mm10GRCm38
MGSCv37195,206,014 - 95,239,365 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36195,139,843 - 95,167,980 (-)NCBIMGSCv36mm8
Celera196,254,103 - 96,287,403 (-)NCBICelera
Cytogenetic Map1DNCBI
cM Map147.24NCBI
Pask
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr89101,291,673 - 101,333,288 (-)NCBIGRCr8
mRatBN7.2993,844,275 - 93,886,036 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl993,844,278 - 93,885,111 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx9102,279,835 - 102,320,665 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.09107,415,644 - 107,456,467 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.09105,771,786 - 105,812,609 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.09100,450,595 - 100,479,719 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl9100,450,586 - 100,479,868 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.09100,106,950 - 100,136,074 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4992,582,177 - 92,623,004 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1992,786,946 - 92,827,773 (-)NCBI
Celera991,379,229 - 91,420,042 (-)NCBICelera
Cytogenetic Map9q36NCBI
Pask
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_004955542555,030 - 578,227 (+)EnsemblChiLan1.0
ChiLan1.0NW_004955542539,806 - 578,496 (+)NCBIChiLan1.0ChiLan1.0
PASK
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12551,145,094 - 51,181,040 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2551,144,912 - 51,177,818 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2551,358,398 - 51,393,714 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02551,340,211 - 51,375,472 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2551,338,043 - 51,375,448 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12551,187,899 - 51,223,198 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02550,927,406 - 50,962,618 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02551,203,734 - 51,238,468 (-)NCBIUU_Cfam_GSD_1.0
Pask
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405303192,515,388 - 192,555,345 (-)NCBIHiC_Itri_2
SpeTri2.0NW_004936745664,062 - 704,027 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
PASK
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl15139,890,178 - 139,917,069 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.115139,887,439 - 139,917,887 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.215155,006,110 - 155,031,416 (-)NCBISscrofa10.2Sscrofa10.2susScr3
PASK
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.110127,156,577 - 127,206,745 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl10127,156,558 - 127,199,845 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604072,175,714 - 72,226,448 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Pask
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248475,216,441 - 5,238,908 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248475,215,626 - 5,246,540 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSPPAT00000046611   ⟹   ENSPPAP00000023786
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl2B247,162,011 - 247,214,803 (-)Ensembl
RefSeq Acc Id: ENSPPAT00000046616   ⟹   ENSPPAP00000023791
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl2B247,204,408 - 247,208,651 (-)Ensembl
RefSeq Acc Id: XM_003813055   ⟹   XP_003813103
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v213143,795,782 - 143,849,595 (-)NCBI
NHGRI_mPanPan12B143,810,747 - 143,864,491 (-)NCBI
Mhudiblu_PPA_v02B128,364,745 - 128,418,164 (-)NCBI
PanPan1.12B247,162,011 - 247,214,970 (-)NCBI
Sequence:
RefSeq Acc Id: XM_008965618   ⟹   XP_008963866
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v213143,795,782 - 143,850,257 (-)NCBI
NHGRI_mPanPan12B143,810,747 - 143,865,153 (-)NCBI
Mhudiblu_PPA_v02B128,364,745 - 128,418,837 (-)NCBI
PanPan1.12B247,162,011 - 247,215,451 (-)NCBI
Sequence:
RefSeq Acc Id: XM_055109310   ⟹   XP_054965285
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v213143,795,782 - 143,850,798 (-)NCBI
NHGRI_mPanPan12B143,810,747 - 143,865,694 (-)NCBI
Protein Sequences
Protein RefSeqs XP_003813103 (Get FASTA)   NCBI Sequence Viewer  
  XP_008963866 (Get FASTA)   NCBI Sequence Viewer  
  XP_054965285 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSPPAP00000023786.1
  ENSPPAP00000023791.1
Reference Protein Sequences
RefSeq Acc Id: XP_008963866   ⟸   XM_008965618
- Peptide Label: isoform X2
- UniProtKB: A0A2R9B473 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_003813103   ⟸   XM_003813055
- Peptide Label: isoform X2
- UniProtKB: A0A2R9B473 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSPPAP00000023791   ⟸   ENSPPAT00000046616
RefSeq Acc Id: ENSPPAP00000023786   ⟸   ENSPPAT00000046611
RefSeq Acc Id: XP_054965285   ⟸   XM_055109310
- Peptide Label: isoform X1
- UniProtKB: A0A2R9B473 (UniProtKB/TrEMBL)
Protein Domains
PAS   Protein kinase


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSPPAG00000035044 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSPPAT00000046611.1 UniProtKB/TrEMBL
  ENSPPAT00000046616.1 UniProtKB/TrEMBL
Gene3D-CATH PAS domain UniProtKB/TrEMBL
  Transferase(Phosphotransferase) domain 1 UniProtKB/TrEMBL
InterPro Kinase-like_dom_sf UniProtKB/TrEMBL
  PAS UniProtKB/TrEMBL
  PAS-like_dom_sf UniProtKB/TrEMBL
  Prot_kinase_dom UniProtKB/TrEMBL
  Protein_kinase_ATP_BS UniProtKB/TrEMBL
  Ser/Thr_kinase_AS UniProtKB/TrEMBL
KEGG Report pps:100986747 UniProtKB/TrEMBL
NCBI Gene PASK ENTREZGENE
PANTHER MAP/MICROTUBULE AFFINITY-REGULATING KINASE UniProtKB/TrEMBL
  PAS DOMAIN-CONTAINING SERINE/THREONINE-PROTEIN KINASE UniProtKB/TrEMBL
Pfam PAS_9 UniProtKB/TrEMBL
  Pkinase UniProtKB/TrEMBL
PROSITE PAS UniProtKB/TrEMBL
  PROTEIN_KINASE_ATP UniProtKB/TrEMBL
  PROTEIN_KINASE_DOM UniProtKB/TrEMBL
  PROTEIN_KINASE_ST UniProtKB/TrEMBL
SMART PAS UniProtKB/TrEMBL
  S_TKc UniProtKB/TrEMBL
Superfamily-SCOP SSF55785 UniProtKB/TrEMBL
  SSF56112 UniProtKB/TrEMBL
UniProt A0A2R9B473 ENTREZGENE, UniProtKB/TrEMBL
  A0A2R9B476_PANPA UniProtKB/TrEMBL