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Gene: Ppp1r11 (protein phosphatase 1, regulatory (inhibitor) subunit 11) Rattus norvegicus

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Symbol:

Ppp1r11

Name:

protein phosphatase 1, regulatory (inhibitor) subunit 11

RGD ID:

1303163

Description:

Predicted to enable protein phosphatase 1 binding activity; protein serine/threonine phosphatase inhibitor activity; and ubiquitin protein ligase activity. Predicted to be involved in defense response to Gram-positive bacterium; negative regulation of cytokine production; and ubiquitin-dependent protein catabolic process. Predicted to be located in cytoplasm. Predicted to be active in nucleus. Orthologous to human PPP1R11 (protein phosphatase 1 regulatory inhibitor subunit 11); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene; 2,6-dinitrotoluene.

Type:

protein-coding

RefSeq Status:

VALIDATED

Previously known as:

E3 ubiquitin-protein ligase PPP1R11; HcgV; MGC94346; protein phosphatase 1 regulatory subunit 11; t-complex testis expressed-5; Tctex5

RGD Orthologs

Alliance Orthologs

More Info

more info ...

Latest Assembly:

GRCr8 - GRCr8 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	20	1,606,583 - 1,610,090 (+)	NCBI		GRCr8
mRatBN7.2	20	1,601,350 - 1,604,857 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	20	1,601,346 - 1,604,846 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	20	1,654,115 - 1,657,630 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	20	1,657,612 - 1,661,127 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	20	1,599,076 - 1,602,598 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	20	2,094,931 - 2,098,438 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	20	2,094,931 - 2,098,433 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	20	4,131,645 - 4,135,152 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	20	1,694,086 - 1,697,593 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	20	1,694,117 - 1,697,205 (+)	NCBI
Celera	20	2,309,914 - 2,313,421 (+)	NCBI		Celera
Cytogenetic Map	20	p12	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

megacolon (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

1,2-dimethylhydrazine (ISO)

2,3,7,8-tetrachlorodibenzodioxine (EXP,ISO)

2,4-dinitrotoluene (EXP)

2,6-dinitrotoluene (EXP)

2-palmitoylglycerol (ISO)

5-aza-2'-deoxycytidine (ISO)

6-propyl-2-thiouracil (EXP)

antirheumatic drug (ISO)

aristolochic acid A (ISO)

Aroclor 1254 (ISO)

benzo[a]pyrene (ISO)

benzo[a]pyrene diol epoxide I (ISO)

bisphenol A (EXP,ISO)

cadmium dichloride (EXP,ISO)

caffeine (ISO)

casticin (ISO)

chlorpyrifos (ISO)

cisplatin (ISO)

cyclosporin A (ISO)

doxorubicin (ISO)

fenthion (ISO)

finasteride (EXP)

flutamide (EXP)

folic acid (ISO)

gentamycin (EXP)

ivermectin (ISO)

lead(0) (ISO)

methidathion (ISO)

ochratoxin A (EXP)

paracetamol (ISO)

resveratrol (ISO)

sodium arsenite (ISO)

thalidomide (ISO)

trichloroethene (EXP)

triphenyl phosphate (ISO)

Triptolide (ISO)

triptonide (ISO)

trovafloxacin (ISO)

vinclozolin (EXP)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

defense response to Gram-positive bacterium (ISO,ISS)

negative regulation of cytokine production (ISO,ISS)

protein ubiquitination (IEA)

ubiquitin-dependent protein catabolic process (ISO,ISS)

Cellular Component

cytoplasm (ISO)

nucleus (IBA)

Molecular Function

phosphatase binding (ISO)

protein binding (ISO)

protein phosphatase 1 binding (IBA)

protein phosphatase inhibitor activity (ISO,TAS)

protein serine/threonine phosphatase inhibitor activity (IBA)

ubiquitin protein ligase activity (ISO,ISS)

References

References - curated

#	Reference Title	Reference Citation
1.	Transcriptional analysis of the 69-kb sequence centromeric to HLA-J: a dense and complex structure of five genes.	Coriton O, etal., Mamm Genome 2000 Dec;11(12):1127-31.
2.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
3.	ClinVar Automated Import and Annotation Pipeline	RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
4.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions
5.	Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.	Strausberg RL, etal., Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903. Epub 2002 Dec 11.

Additional References at PubMed

PMID:9843442	PMID:15060004	PMID:15489334	PMID:19300506	PMID:27805901

Genomics

Comparative Map Data

Ppp1r11
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	20	1,606,583 - 1,610,090 (+)	NCBI		GRCr8
mRatBN7.2	20	1,601,350 - 1,604,857 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	20	1,601,346 - 1,604,846 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	20	1,654,115 - 1,657,630 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	20	1,657,612 - 1,661,127 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	20	1,599,076 - 1,602,598 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	20	2,094,931 - 2,098,438 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	20	2,094,931 - 2,098,433 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	20	4,131,645 - 4,135,152 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	20	1,694,086 - 1,697,593 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	20	1,694,117 - 1,697,205 (+)	NCBI
Celera	20	2,309,914 - 2,313,421 (+)	NCBI		Celera
Cytogenetic Map	20	p12	NCBI

PPP1R11
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	6	30,061,265 - 30,070,333 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	6	30,066,709 - 30,070,333 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	6	30,034,975 - 30,038,110 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	6	30,142,911 - 30,146,089 (+)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	6	30,142,967 - 30,146,085	NCBI
Celera	6	31,633,185 - 31,636,363 (+)	NCBI		Celera
Cytogenetic Map	6	p22.1	NCBI
HuRef	6	29,833,104 - 29,836,282 (+)	NCBI		HuRef
CHM1_1	6	30,036,981 - 30,040,159 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	6	29,931,133 - 29,934,607 (+)	NCBI		T2T-CHM13v2.0

Ppp1r11
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	17	37,259,247 - 37,262,684 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	17	37,259,248 - 37,262,633 (-)	Ensembl		GRCm39 Ensembl
GRCm38	17	36,948,355 - 36,951,792 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	17	36,948,356 - 36,951,741 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	17	37,085,300 - 37,088,737 (-)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	17	36,557,340 - 36,569,082 (-)	NCBI		MGSCv36	mm8
Celera	17	40,371,894 - 40,375,330 (-)	NCBI		Celera
Cytogenetic Map	17	B1	NCBI
cM Map	17	19.16	NCBI

Ppp1r11
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955583	198,233 - 202,486 (+)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955583	198,233 - 201,312 (+)	NCBI	ChiLan1.0	ChiLan1.0

PPP1R11
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	5	44,660,268 - 44,667,412 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	6	40,623,201 - 40,631,034 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	6	29,844,971 - 29,851,792 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	6	30,515,139 - 30,518,390 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	6	30,515,139 - 30,518,384 (+)	Ensembl	panpan1.1		panPan2

PPP1R11
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	35	26,289,430 - 26,292,281 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	35	26,289,471 - 26,291,497 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
ROS_Cfam_1.0	35	26,597,984 - 26,600,853 (+)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	35	26,597,618 - 26,600,847 (+)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	35	26,252,583 - 26,255,419 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	35	26,313,257 - 26,316,092 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	35	27,783,473 - 27,786,313 (+)	NCBI		UU_Cfam_GSD_1.0

Ppp1r11
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024404946	32,615,984 - 32,619,307 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936723	970,226 - 975,952 (-)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936723	973,516 - 975,930 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

PPP1R11
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	7	22,633,815 - 22,636,987 (+)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	7	22,634,074 - 22,636,987 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	7	24,991,270 - 24,994,181 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

PPP1R11
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	17	42,429,564 - 42,432,758 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	17	42,430,478 - 42,432,659 (-)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666044	29,722,307 - 29,725,544 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Ppp1r11
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624754	25,336,151 - 25,338,388 (-)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624754	25,336,151 - 25,338,389 (-)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

miRNA Target Status

Predicted Target Of

	Summary Value
Count of predictions:	374
Count of miRNA genes:	181
Interacting mature miRNAs:	191
Transcripts:	ENSRNOT00000001013
Prediction methods:	Microtar, Miranda, Rnahybrid
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (GRCr8)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
2306850	Pia40	Pristane induced arthritis QTL 40		0.0001	joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	20	1533200	5306452	Rat
61474	Eae1	Experimental allergic encephalomyelitis QTL 1	3		nervous system integrity trait (VT:0010566)	experimental autoimmune encephalomyelitis severity score (CMO:0001419)	20	1	6693431	Rat
2317057	Aia27	Adjuvant induced arthritis QTL 27	2.83		joint integrity trait (VT:0010548)	right rear ankle joint diameter (CMO:0002150)	20	1	26925056	Rat
1641915	Colcr9	Colorectal carcinoma resistance QTL 9	2.97	0.0024	intestine integrity trait (VT:0010554)	benign colorectal tumor number (CMO:0001795)	20	1	33724594	Rat
7411668	Foco32	Food consumption QTL 32	8	0.001	eating behavior trait (VT:0001431)	feed conversion ratio (CMO:0001312)	20	1	36600300	Rat
2305926	Iddm37	Insulin dependent diabetes mellitus QTL 37	6		blood glucose amount (VT:0000188)	plasma glucose level (CMO:0000042)	20	1533083	46533083	Rat
1354642	Despr15	Despair related QTL 15		0.0027	locomotor behavior trait (VT:0001392)	amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)	20	1	24164241	Rat
1558640	Prcs2	Prostate cancer susceptibility QTL 2	3.3		prostate integrity trait (VT:0010571)	percentage of study population developing ventral prostate tumorous lesions during a period of time (CMO:0000943)	20	1	34066551	Rat
8694189	Bw153	Body weight QTL 153	3.13	0.001	body mass (VT:0001259)	body weight gain (CMO:0000420)	20	1	29193376	Rat
70154	Insul2	Insulin level QTL 2	3.75		blood insulin amount (VT:0001560)	plasma insulin level (CMO:0000342)	20	1	6693431	Rat
4889857	Pur27	Proteinuria QTL 27	12.2	0.001	urine total protein amount (VT:0000032)	urine total protein excretion rate (CMO:0000756)	20	1	27341128	Rat
724519	Bp144	Blood pressure QTL 144		0.001	arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	20	1	3629303	Rat
9590109	Sffal8	Serum free fatty acids level QTL 8	5.32	0.01	blood free fatty acid amount (VT:0001553)	plasma free fatty acids level (CMO:0000546)	20	1	29193376	Rat
9589155	Insul32	Insulin level QTL 32	6.38	0.001	blood insulin amount (VT:0001560)	plasma insulin level (CMO:0000342)	20	1	29193376	Rat
9590275	Scort15	Serum corticosterone level QTL 15	3.48	0.001	blood corticosterone amount (VT:0005345)	plasma corticosterone level (CMO:0001173)	20	1	29193376	Rat
7411650	Foco23	Food consumption QTL 23	20.7	0.001	eating behavior trait (VT:0001431)	feed conversion ratio (CMO:0001312)	20	1	29193376	Rat
61432	Cia1	Collagen induced arthritis QTL 1			joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	20	1	14100378	Rat
2317851	Alcrsp22	Alcohol response QTL 22	3.2	0.05	response to alcohol trait (VT:0010489)	duration of loss of righting reflex (CMO:0002289)	20	1	27341128	Rat
1641893	Alcrsp7	Alcohol response QTL 7			response to alcohol trait (VT:0010489)	duration of loss of righting reflex (CMO:0002289)	20	1	27341128	Rat
6893685	Bw111	Body weight QTL 111	2.7	0.004	body mass (VT:0001259)	body weight (CMO:0000012)	20	1	32578510	Rat
9590252	Scort12	Serum corticosterone level QTL 12	20.46	0.001	blood corticosterone amount (VT:0005345)	plasma corticosterone level (CMO:0001173)	20	1	36600300	Rat

Markers in Region

Tctex5

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	20	1,603,657 - 1,603,859 (+)	MAPPER	mRatBN7.2
Rnor_6.0	20	2,097,239 - 2,097,440	NCBI	Rnor6.0
Rnor_5.0	20	4,133,953 - 4,134,154	UniSTS	Rnor5.0
RGSC_v3.4	20	1,696,394 - 1,696,595	UniSTS	RGSC3.4
Celera	20	2,312,222 - 2,312,423	UniSTS
Cytogenetic Map	20	p12	UniSTS

RH131374

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	20	1,604,849 - 1,605,054 (+)	MAPPER	mRatBN7.2
Rnor_6.0	20	2,098,431 - 2,098,635	NCBI	Rnor6.0
Rnor_5.0	20	4,135,145 - 4,135,349	UniSTS	Rnor5.0
RGSC_v3.4	20	1,697,586 - 1,697,790	UniSTS	RGSC3.4
Celera	20	2,313,414 - 2,313,618	UniSTS
RH 3.4 Map	20	15.8	UniSTS
Cytogenetic Map	20	p12	UniSTS

RH131842

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	20	1,604,598 - 1,604,808 (+)	MAPPER	mRatBN7.2
Rnor_6.0	20	2,098,180 - 2,098,389	NCBI	Rnor6.0
Rnor_5.0	20	4,134,894 - 4,135,103	UniSTS	Rnor5.0
RGSC_v3.4	20	1,697,335 - 1,697,544	UniSTS	RGSC3.4
Celera	20	2,313,163 - 2,313,372	UniSTS
RH 3.4 Map	20	11.0	UniSTS
Cytogenetic Map	20	p12	UniSTS

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Download All Expressed Objects for this Gene

alimentary part of gastrointestinal system	appendage	circulatory system	ectoderm	endocrine system	endoderm	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	mesenchyme	mesoderm	nervous system	renal system	reproductive system	respiratory system
9	11	49	113	91	90	59	25	59	6	218	97	93	45	60	31

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_212542	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_006255870	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039098471	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AC108572	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BC079252	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BX883051	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH474093	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CX571132	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	EX488885	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	FM088354	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000020	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSRNOT00000001013 ⟹ ENSRNOP00000001013

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	20	1,601,346 - 1,604,846 (+)	Ensembl
Rnor_6.0 Ensembl	20	2,094,931 - 2,098,433 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000078362

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0 Ensembl	20	2,095,237 - 2,097,590 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000088757

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0 Ensembl	20	2,095,275 - 2,097,735 (+)	Ensembl

RefSeq Acc Id:

NM_212542 ⟹ NP_997707

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	20	1,606,583 - 1,610,090 (+)	NCBI
mRatBN7.2	20	1,601,350 - 1,604,857 (+)	NCBI
Rnor_6.0	20	2,094,931 - 2,098,438 (+)	NCBI
Rnor_5.0	20	4,131,645 - 4,135,152 (+)	NCBI
RGSC_v3.4	20	1,694,086 - 1,697,593 (+)	RGD
Celera	20	2,309,914 - 2,313,421 (+)	RGD

Sequence:

show sequence

CCGGAAGTGAAAGGCCGGAAGTGGGGTTGGACAGGTTTTTCCCCAGGGGTGGGGAAGCAGAGGC
CCTGGAGGAGTAGGGGAGATTAAGAAGCCAGAGCATCCTGGCCTCTACTCCGAATCGTGTACCG
GTTCTCTTAGATCTCAGAGGCGCAGAAAAAGGGAGGGGTGTCTCATCCTGGTTCCTCGCTTTTC
GCTTTAGCCATGGCGGAGGCAGGAGCCGGGGGGCTGAGTGAGACCGTCACTGAGACAACGGTTA
CCGTGACAACCGAGCCCGAGAATCGGAGCCTAACCATTAAACTTCGGAAACGGAAGCCAGAGAA
GAAGGTGGAGTGGTCAAGTGACACTGTGGACAATGAGCATATGGGCCGCCGCTCATCGAAATGC
TGCTGTATTTATGAGAAACCTCGGGCCTTTGGTGAGAGCTCCACCGAGAGTGATGAGGATGAAG
AGGAAGGCTGTGGTCATACGCACTGTGTACGGGGTCACCGCAAAGGACGGCGTCCTACAACCCC
AGGACCCACCCCAACCACTCCTCCACAGCCTCCTGATCCCTCTCAGCCCCCTCCAGGACCTATG
CAGCACTAAATCCCTCTCACCATTCATGTGTCTGCCTGGCCCCAAATGTATCCATCTGACATGG
GGACTTAACCCATGGTCTGGTCCCTTCTCCCGCCCCCTTCTTCCCTCTCCTGCCTGATTGAGAA
GAGGAAGAGGAGGGCGGATACAGACCCTGTAATTCTGACTTGCTGCTGTTCCAGAACCCAGGCT
TTGGGTTCTCCCAGCCCCTTCTTCCCTACAGTTTGCCCCTGTGCCTGGGATCCAGGCATCTTGG
TCCCAATTTATCCCTTTTGTTCTCACTGCCAAACTACCTGTCCTGGGATCCAGTTATTTTGGCC
ACCTGCACCCTCAGCTTGAGTCCCAAGCACTTCAACTGGGTTTCCAACTGTCCCAGCTTTCACT
GCCAGGGTCCCAATCAAATTCCAGGCAATCTTGTACCCCAGCTCTGCATATTAATCCTGGCTTG
TGGTTCTTCCATTGACGCAGTTTTCCTAAATCTTAGTTCTTGCCTGTGGGATATAAGGTTGTGT
GGAGACCATAGGGCTCCCTGGCCCTTCTGCTCCTCTTACCCCTTCTGGCTCTCCAGAGGAGTTA
GGAGAGGTCTTTGTCATTCACACCTCTGATGGGAAGTGGAACCAAAAGTAGTCATGTCTTGAAT
ATAACATTTCTGACAAAGCTAGCTGAGACCACTGACCTAGAGTCAACGATTCTCTCAGCCTTTA
ATCTTTGAGCCTCAGCATTGGTGTCCTGGCGGCCGGACTCCCTAAAAGGAAGGAGGGAGAAAGC
AGAGAGACGAGGGGACAGGCCCCTGCAGTGCACTCCTACCCTTTCCTTCCTAGGCCTTGGAGTC
TGCCAACCCAGCTGTCTTGCTCTCTCAGCCTCCCCAGCTGGTGCTGGGACCTGGGTGTTATCCT
CTAGGCTCCAGCTGTGCACAGCGCAGAGATCAGCAAAACCCACGGCACCACTTAGATCTCATTT
ATTGACACAGATGCACAAAATAAATAACCCAACATTGCACAACGTGT

hide sequence

RefSeq Acc Id:

XM_006255870 ⟹ XP_006255932

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	20	1,606,858 - 1,610,082 (+)	NCBI
mRatBN7.2	20	1,601,656 - 1,604,852 (+)	NCBI
Rnor_6.0	20	2,095,242 - 2,098,428 (+)	NCBI
Rnor_5.0	20	4,131,645 - 4,135,152 (+)	NCBI

Sequence:

show sequence

GAAGCACTGGGAGGGGGATGGGGGTCTGGAAAGTTGGAGGGTTTGGGATCTGGGACCTGTGGGG
TTTACTCTTACTGGGAAAATCGGAAGTGACTAGAAATGCTTGGAGCGGCTCAGATGGTTCAAGT
GACTCGTCAAGGATTGTTTAATCTGCAGTTACAATTAGAGTATAGGTGTTACGGCTTGGGGTGG
TGGTCTGTGTACGTAATAAACGGAAACTGGACCAAGGAAGGTACTGGAAGGAAGCGAAACGCCA
TTTGAGAAAGCATGGTTTTGGAGGCAAGCGTGCAGAACGAGTACTTACCAGTAGTGCTCGCCAA
TAGATAGTCATGGAATGGGAGAATCGGAGCCTAACCATTAAACTTCGGAAACGGAAGCCAGAGA
AGAAGGTGGAGTGGTCAAGTGACACTGTGGACAATGAGCATATGGGCCGCCGCTCATCGAAATG
CTGCTGTATTTATGAGAAACCTCGGGCCTTTGGTGAGAGCTCCACCGAGAGTGATGAGGATGAA
GAGGAAGGCTGTGGTCATACGCACTGTGTACGGGGTCACCGCAAAGGACGGCGTCCTACAACCC
CAGGACCCACCCCAACCACTCCTCCACAGCCTCCTGATCCCTCTCAGCCCCCTCCAGGACCTAT
GCAGCACTAAATCCCTCTCACCATTCATGTGTCTGCCTGGCCCCAAATGTATCCATCTGACATG
GGGACTTAACCCATGGTCTGGTCCCTTCTCCCGCCCCCTTCTTCCCTCTCCTGCCTGATTGAGA
AGAGGAAGAGGAGGGCGGATACAGACCCTGTAATTCTGACTTGCTGCTGTTCCAGAACCCAGGC
TTTGGGTTCTCCCAGCCCCTTCTTCCCTACAGTTTGCCCCTGTGCCTGGGATCCAGGCATCTTG
GTCCCAATTTATCCCTTTTGTTCTCACTGCCAAACTACCTGTCCTGGGATCCAGTTATTTTGGC
CACCTGCACCCTCAGCTTGAGTCCCAAGCACTTCAACTGGGTTTCCAACTGTCCCAGCTTTCAC
TGCCAGGGTCCCAATCAAATTCCAGGCAATCTTGTACCCCAGCTCTGCATATTAATCCTGGCTT
GTGGTTCTTCCATTGACGCAGTTTTCCTAAATCTTAGTTCTTGCCTGTGGGATATAAGGTTGTG
TGGAGACCATAGGGCTCCCTGGCCCTTCTGCTCCTCTTACCCCTTCTGGCTCTCCAGAGGAGTT
AGGAGAGGTCTTTGTCATTCACACCTCTGATGGGAAGTGGAACCAAAAGTAGTCATGTCTTGAA
TATAACATTTCTGACAAAGCTAGCTGAGACCACTGACCTAGAGTCAACGATTCTCTCAGCCTTT
AATCTTTGAGCCTCAGCATTGGTGTCCTGGCGGCCGGACTCCCTAAAAGGAAGGAGGGAGAAAG
CAGAGAGACGAGGGGACAGGCCCCTGCAGTGCACTCCTACCCTTTCCTTCCTAGGCCTTGGAGT
CTGCCAACCCAGCTGTCTTGCTCTCTCAGCCTCCCCAGCTGGTGCTGGGACCTGGGTGTTATCC
TCTAGGCTCCAGCTGTGCACAGCGCAGAGATCAGCAAAACCCACGGCACCACTTAGATCTCATT
TATTGACACAGATGCACAAAATAAATAACCCAACATTG

hide sequence

RefSeq Acc Id:

XM_039098471 ⟹ XP_038954399

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	20	1,606,584 - 1,610,082 (+)	NCBI
mRatBN7.2	20	1,601,907 - 1,604,852 (+)	NCBI

Protein Sequences


Protein RefSeqs	NP_997707	(Get FASTA)	NCBI Sequence Viewer
	XP_006255932	(Get FASTA)	NCBI Sequence Viewer
	XP_038954399	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAH79252	(Get FASTA)	NCBI Sequence Viewer
	CAE84061	(Get FASTA)	NCBI Sequence Viewer
	EDL84611	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000001013.5
	ENSRNOP00055012313
	ENSRNOP00060004111
	ENSRNOP00065040396
GenBank Protein	Q6MFY6	(Get FASTA)	NCBI Sequence Viewer

RefSeq Acc Id:	NP_997707 ⟸ NM_212542
- UniProtKB:	Q6AXZ8 (UniProtKB/Swiss-Prot), Q6MFY6 (UniProtKB/Swiss-Prot), A6KR78 (UniProtKB/TrEMBL)
- Sequence:	show sequence MAEAGAGGLSETVTETTVTVTTEPENRSLTIKLRKRKPEKKVEWSSDTVDNEHMGRRSSKCCCI YEKPRAFGESSTESDEDEEEGCGHTHCVRGHRKGRRPTTPGPTPTTPPQPPDPSQPPPGPMQH hide sequence

RefSeq Acc Id:	XP_006255932 ⟸ XM_006255870
- Peptide Label:	isoform X2
- Sequence:	show sequence MEWENRSLTIKLRKRKPEKKVEWSSDTVDNEHMGRRSSKCCCIYEKPRAFGESSTESDEDEEEG CGHTHCVRGHRKGRRPTTPGPTPTTPPQPPDPSQPPPGPMQH hide sequence

Ensembl Acc Id:

ENSRNOP00000001013 ⟸ ENSRNOT00000001013

RefSeq Acc Id:	XP_038954399 ⟸ XM_039098471
- Peptide Label:	isoform X1

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-Q6MFY6-F1-model_v2	AlphaFold	Q6MFY6	1-127	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Promoters

RGD ID:

13701273

Promoter ID:

EPDNEW_R11797

Type:

initiation region

Name:

Ppp1r11_1

Description:

protein phosphatase 1, regulatory subunit 11

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Experiment Methods:

Single-end sequencing.

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0	20	2,094,989 - 2,095,049	EPDNEW

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:1303163	AgrOrtholog
BioCyc Gene	G2FUF-4978	BioCyc
Ensembl Genes	ENSRNOG00000000780	Ensembl, UniProtKB/TrEMBL
	ENSRNOG00055009082	UniProtKB/Swiss-Prot
	ENSRNOG00060003409	UniProtKB/Swiss-Prot
	ENSRNOG00065028577	UniProtKB/Swiss-Prot
Ensembl Transcript	ENSRNOT00000001013.8	UniProtKB/TrEMBL
	ENSRNOT00055015375	UniProtKB/Swiss-Prot
	ENSRNOT00060005613	UniProtKB/Swiss-Prot
	ENSRNOT00065049261	UniProtKB/Swiss-Prot
IMAGE_CLONE	IMAGE:7133103	IMAGE-MGC_LOAD
InterPro	PPI_Ypi1	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report	rno:294207	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
MGC_CLONE	MGC:94346	IMAGE-MGC_LOAD
NCBI Gene	294207	ENTREZGENE
PANTHER	E3 UBIQUITIN-PROTEIN LIGASE PPP1R11	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	E3 UBIQUITIN-PROTEIN LIGASE PPP1R11-RELATED	UniProtKB/TrEMBL, UniProtKB/Swiss-Prot
Pfam	PPI_Ypi1	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen	Ppp1r11	PhenoGen
RatGTEx	ENSRNOG00000000780	RatGTEx
	ENSRNOG00055009082	RatGTEx
	ENSRNOG00060003409	RatGTEx
	ENSRNOG00065028577	RatGTEx
UniProt	A0A8L2Q0D7_RAT	UniProtKB/TrEMBL
	A6KR78	ENTREZGENE, UniProtKB/TrEMBL
	PP1RB_RAT	UniProtKB/Swiss-Prot
	Q6AXZ8	ENTREZGENE
	Q6MFY6	ENTREZGENE
UniProt Secondary	Q6AXZ8	UniProtKB/Swiss-Prot

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2006-03-30	Ppp1r11	protein phosphatase 1, regulatory (inhibitor) subunit 11			Symbol and Name status set to approved	1299863	APPROVED
2005-07-14	Ppp1r11	protein phosphatase 1, regulatory (inhibitor) subunit 11			Symbol and Name status set to provisional	70820	PROVISIONAL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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Imported Disease Annotations - ClinVar