PPP1R11 (protein phosphatase 1 regulatory inhibitor subunit 11) - Rat Genome Database

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Gene: PPP1R11 (protein phosphatase 1 regulatory inhibitor subunit 11) Sus scrofa
Analyze
Symbol: PPP1R11
Name: protein phosphatase 1 regulatory inhibitor subunit 11
RGD ID: 14276841
Description: ENCODES a protein that exhibits phosphatase binding (inferred); protein phosphatase 1 binding (inferred); protein phosphatase inhibitor activity (inferred); INVOLVED IN defense response to Gram-positive bacterium (ortholog); negative regulation of cytokine production (ortholog); ASSOCIATED WITH genetic disease (ortholog); megacolon (ortholog); FOUND IN cytoplasm (ortholog); INTERACTS WITH deoxynivalenol
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: E3 ubiquitin-protein ligase PPP1R11; protein phosphatase 1 regulatory subunit 11
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Sscrofa11.1 - Pig Sscrofa11.1 Assembly
Position:
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl722,633,859 - 22,636,971 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1722,634,074 - 22,636,987 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2724,991,270 - 24,994,181 (-)NCBISscrofa10.2Sscrofa10.2susScr3
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
cytoplasm  (ISO)
nucleus  (IBA,IEA)

References
Additional References at PubMed
PMID:14681463   PMID:16328468   PMID:17145712   PMID:18284617   PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
PPP1R11
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl722,633,859 - 22,636,971 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1722,634,074 - 22,636,987 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2724,991,270 - 24,994,181 (-)NCBISscrofa10.2Sscrofa10.2susScr3
PPP1R11
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38630,061,265 - 30,070,333 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl630,066,709 - 30,070,333 (+)EnsemblGRCh38hg38GRCh38
GRCh37630,034,975 - 30,038,110 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36630,142,911 - 30,146,089 (+)NCBINCBI36Build 36hg18NCBI36
Build 34630,142,967 - 30,146,085NCBI
Celera631,633,185 - 31,636,363 (+)NCBICelera
Cytogenetic Map6p22.1NCBI
HuRef629,833,104 - 29,836,282 (+)NCBIHuRef
CHM1_1630,036,981 - 30,040,159 (+)NCBICHM1_1
T2T-CHM13v2.0629,931,133 - 29,934,607 (+)NCBIT2T-CHM13v2.0
Ppp1r11
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391737,259,247 - 37,262,684 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1737,259,248 - 37,262,633 (-)EnsemblGRCm39 Ensembl
GRCm381736,948,355 - 36,951,792 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1736,948,356 - 36,951,741 (-)EnsemblGRCm38mm10GRCm38
MGSCv371737,085,300 - 37,088,737 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361736,557,340 - 36,569,082 (-)NCBIMGSCv36mm8
Celera1740,371,894 - 40,375,330 (-)NCBICelera
Cytogenetic Map17B1NCBI
cM Map1719.16NCBI
Ppp1r11
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8201,606,583 - 1,610,090 (+)NCBIGRCr8
mRatBN7.2201,601,350 - 1,604,857 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl201,601,346 - 1,604,846 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx201,654,115 - 1,657,630 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0201,657,612 - 1,661,127 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0201,599,076 - 1,602,598 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0202,094,931 - 2,098,438 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl202,094,931 - 2,098,433 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0204,131,645 - 4,135,152 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4201,694,086 - 1,697,593 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1201,694,117 - 1,697,205 (+)NCBI
Celera202,309,914 - 2,313,421 (+)NCBICelera
Cytogenetic Map20p12NCBI
Ppp1r11
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_004955583198,233 - 202,486 (+)EnsemblChiLan1.0
ChiLan1.0NW_004955583198,233 - 201,312 (+)NCBIChiLan1.0ChiLan1.0
PPP1R11
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2544,660,268 - 44,667,412 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1640,623,201 - 40,631,034 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0629,844,971 - 29,851,792 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1630,515,139 - 30,518,390 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl630,515,139 - 30,518,384 (+)Ensemblpanpan1.1panPan2
PPP1R11
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.13526,289,430 - 26,292,281 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl3526,289,471 - 26,291,497 (+)EnsemblCanFam3.1canFam3CanFam3.1
ROS_Cfam_1.03526,597,984 - 26,600,853 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl3526,597,618 - 26,600,847 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.13526,252,583 - 26,255,419 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.03526,313,257 - 26,316,092 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.03527,783,473 - 27,786,313 (+)NCBIUU_Cfam_GSD_1.0
Ppp1r11
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494632,615,984 - 32,619,307 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936723970,226 - 975,952 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936723973,516 - 975,930 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
PPP1R11
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11742,429,564 - 42,432,758 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1742,430,478 - 42,432,659 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604429,722,307 - 29,725,544 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Ppp1r11
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462475425,336,151 - 25,338,388 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462475425,336,151 - 25,338,389 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in PPP1R11
38 total Variants

Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system hemolymphoid system musculoskeletal system nervous system renal system reproductive system respiratory system
High
Medium 10 2 3 5 1 23 2 3 3
Low 2 1
Below cutoff

Sequence


Reference Sequences
RefSeq Acc Id: ENSSSCT00000001349   ⟹   ENSSSCP00000001318
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl722,633,889 - 22,636,971 (+)Ensembl
RefSeq Acc Id: ENSSSCT00000092486   ⟹   ENSSSCP00000076089
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl722,633,859 - 22,636,971 (+)Ensembl
RefSeq Acc Id: NM_001123166   ⟹   NP_001116638
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1722,634,074 - 22,635,934 (+)NCBI
Sequence:
RefSeq Acc Id: XM_005665697   ⟹   XP_005665754
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1722,634,223 - 22,636,987 (+)NCBI
Sequence:
Reference Protein Sequences
RefSeq Acc Id: NP_001116638   ⟸   NM_001123166
- UniProtKB: B6ICU5 (UniProtKB/TrEMBL),   A0A4X1VLG5 (UniProtKB/TrEMBL),   A0A8D1I3N7 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_005665754   ⟸   XM_005665697
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: ENSSSCP00000001318   ⟸   ENSSSCT00000001349
RefSeq Acc Id: ENSSSCP00000076089   ⟸   ENSSSCT00000092486


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSSCG00000024259 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCG00005020650 UniProtKB/TrEMBL
  ENSSSCG00015012968 UniProtKB/TrEMBL
  ENSSSCG00025028422 UniProtKB/TrEMBL
  ENSSSCG00030049370 UniProtKB/TrEMBL
  ENSSSCG00035060957 UniProtKB/TrEMBL
  ENSSSCG00040066185 UniProtKB/TrEMBL
  ENSSSCG00045022681 UniProtKB/TrEMBL
  ENSSSCG00050076733 UniProtKB/TrEMBL
  ENSSSCG00055030750 UniProtKB/TrEMBL
  ENSSSCG00060078766 UniProtKB/TrEMBL
  ENSSSCG00065079235 UniProtKB/TrEMBL
  ENSSSCG00070024765 UniProtKB/TrEMBL
Ensembl Transcript ENSSSCT00000001349 ENTREZGENE
  ENSSSCT00000001349.4 UniProtKB/TrEMBL
  ENSSSCT00000092486.1 UniProtKB/TrEMBL
  ENSSSCT00005032501.1 UniProtKB/TrEMBL
  ENSSSCT00005032511.1 UniProtKB/TrEMBL
  ENSSSCT00015017114.1 UniProtKB/TrEMBL
  ENSSSCT00025038570.1 UniProtKB/TrEMBL
  ENSSSCT00030068855.1 UniProtKB/TrEMBL
  ENSSSCT00035081853.1 UniProtKB/TrEMBL
  ENSSSCT00040090363.1 UniProtKB/TrEMBL
  ENSSSCT00045038693.1 UniProtKB/TrEMBL
  ENSSSCT00045038731.1 UniProtKB/TrEMBL
  ENSSSCT00050105468.1 UniProtKB/TrEMBL
  ENSSSCT00055061350.1 UniProtKB/TrEMBL
  ENSSSCT00055061351.1 UniProtKB/TrEMBL
  ENSSSCT00060108950.1 UniProtKB/TrEMBL
  ENSSSCT00060108951.1 UniProtKB/TrEMBL
  ENSSSCT00065110154.1 UniProtKB/TrEMBL
  ENSSSCT00065110155.1 UniProtKB/TrEMBL
  ENSSSCT00070049462.1 UniProtKB/TrEMBL
  ENSSSCT00070049463.1 UniProtKB/TrEMBL
InterPro PPI_Ypi1 UniProtKB/TrEMBL
KEGG Report ssc:100141423 UniProtKB/TrEMBL
NCBI Gene PPP1R11 ENTREZGENE
PANTHER E3 UBIQUITIN-PROTEIN LIGASE PPP1R11 UniProtKB/TrEMBL
  PTHR20835 UniProtKB/TrEMBL
Pfam PPI_Ypi1 UniProtKB/TrEMBL
UniProt A0A4X1VLG5 ENTREZGENE
  A0A8D1I3N7 ENTREZGENE, UniProtKB/TrEMBL
  A0A8W4FCQ7_PIG UniProtKB/TrEMBL
  B6ICU5 ENTREZGENE, UniProtKB/TrEMBL
UniProt Secondary A0A4X1VLG5 UniProtKB/TrEMBL
VGNC ID VGNC:91718 ENTREZGENE