Enpp5 (ectonucleotide pyrophosphatase/phosphodiesterase family member 5) - Rat Genome Database

Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Gene: Enpp5 (ectonucleotide pyrophosphatase/phosphodiesterase family member 5) Ictidomys tridecemlineatus
Analyze
Symbol: Enpp5
Name: ectonucleotide pyrophosphatase/phosphodiesterase family member 5
RGD ID: 12731433
Description: ENCODES a protein that exhibits NAD+ diphosphatase activity (inferred); zinc ion binding (inferred); INVOLVED IN cell communication (ortholog); ASSOCIATED WITH COVID-19 (ortholog); Prostatic Neoplasms (ortholog); FOUND IN plasma membrane (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: ectonucleotide pyrophosphatase/phosphodiesterase 5 (putative)
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: SpeTri2.0 - Squirrel SpeTri2.0 Assembly
Position:
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494649,781,793 - 49,790,968 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493647614,169,148 - 14,179,151 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493647614,169,298 - 14,178,930 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References

Genomics

Comparative Map Data
Enpp5
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494649,781,793 - 49,790,968 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493647614,169,148 - 14,179,151 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493647614,169,298 - 14,178,930 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ENPP5
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38646,159,185 - 46,170,980 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl646,159,185 - 46,170,980 (-)EnsemblGRCh38hg38GRCh38
GRCh37646,126,922 - 46,138,717 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36646,235,721 - 46,246,676 (-)NCBINCBI36Build 36hg18NCBI36
Build 34646,235,720 - 46,246,676NCBI
Celera647,680,299 - 47,691,261 (-)NCBICelera
Cytogenetic Map6p21.1NCBI
HuRef645,850,807 - 45,861,762 (-)NCBIHuRef
CHM1_1646,131,010 - 46,141,952 (-)NCBICHM1_1
T2T-CHM13v2.0645,994,273 - 46,006,158 (-)NCBIT2T-CHM13v2.0
Enpp5
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391744,389,693 - 44,397,458 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1744,389,704 - 44,397,458 (+)EnsemblGRCm39 Ensembl
GRCm381744,078,802 - 44,086,567 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1744,078,813 - 44,086,567 (+)EnsemblGRCm38mm10GRCm38
MGSCv371744,215,795 - 44,223,516 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361743,541,924 - 43,549,614 (+)NCBIMGSCv36mm8
Celera1747,500,370 - 47,508,072 (+)NCBICelera
Cytogenetic Map17B3NCBI
cM Map1720.3NCBI
Enpp5
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8924,407,574 - 24,415,029 (-)NCBIGRCr8
mRatBN7.2916,910,187 - 16,917,633 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl916,910,831 - 16,917,480 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx925,494,836 - 25,501,470 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0930,569,359 - 30,575,993 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0928,858,569 - 28,865,203 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0919,469,276 - 19,476,684 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl919,469,706 - 19,476,646 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0918,347,773 - 18,355,164 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4912,574,480 - 12,581,130 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1912,571,802 - 12,578,452 (-)NCBI
Celera914,637,055 - 14,643,705 (-)NCBICelera
Cytogenetic Map9q13NCBI
Enpp5
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495543711,195,391 - 11,204,728 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495543711,195,846 - 11,204,000 (-)NCBIChiLan1.0ChiLan1.0
ENPP5
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2560,642,891 - 60,664,298 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1656,508,953 - 56,530,294 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0645,735,167 - 45,751,671 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1647,013,701 - 47,025,523 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl647,013,699 - 47,025,523 (-)Ensemblpanpan1.1panPan2
ENPP5
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11214,376,278 - 14,387,883 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1214,377,565 - 14,385,171 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1214,408,235 - 14,419,802 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01214,876,522 - 14,888,437 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1214,877,806 - 14,888,470 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11214,392,730 - 14,404,121 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01214,480,941 - 14,492,536 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01214,577,456 - 14,589,058 (-)NCBIUU_Cfam_GSD_1.0
ENPP5
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl740,920,031 - 40,933,326 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1740,920,030 - 40,936,380 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2747,233,579 - 47,249,978 (+)NCBISscrofa10.2Sscrofa10.2susScr3
ENPP5
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11726,082,427 - 26,091,526 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1726,082,451 - 26,092,900 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604446,165,201 - 46,175,504 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Enpp5
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462475414,286,371 - 14,295,501 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462475414,286,337 - 14,294,529 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression

RNA-SEQ Expression


Sequence


Ensembl Acc Id: ENSSTOT00000011892   ⟹   ENSSTOP00000010665
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
SpeTri2.0 EnsemblNW_00493647614,169,148 - 14,179,151 (+)Ensembl
RefSeq Acc Id: XM_005318612   ⟹   XP_005318669
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440494649,781,793 - 49,790,873 (-)NCBI
SpeTri2.0NW_00493647614,169,314 - 14,178,930 (+)NCBI
Sequence:
RefSeq Acc Id: XM_021721850   ⟹   XP_021577525
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440494649,781,793 - 49,790,968 (-)NCBI
SpeTri2.0NW_00493647614,169,298 - 14,178,930 (+)NCBI
Sequence:
RefSeq Acc Id: XM_040282747   ⟹   XP_040138681
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440494649,783,934 - 49,790,872 (-)NCBI
Protein Sequences
Protein RefSeqs XP_005318669 (Get FASTA)   NCBI Sequence Viewer  
  XP_021577525 (Get FASTA)   NCBI Sequence Viewer  
  XP_040138681 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSSTOP00000010665.2
RefSeq Acc Id: XP_005318669   ⟸   XM_005318612
- Peptide Label: isoform X1
- UniProtKB: I3MI62 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_021577525   ⟸   XM_021721850
- Peptide Label: isoform X1
- UniProtKB: I3MI62 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_040138681   ⟸   XM_040282747
- Peptide Label: isoform X2
Ensembl Acc Id: ENSSTOP00000010665   ⟸   ENSSTOT00000011892


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSTOG00000011895 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSSTOT00000011892.3 UniProtKB/TrEMBL
Gene3D-CATH 3.30.1360.180 UniProtKB/TrEMBL
  3.40.720.10 UniProtKB/TrEMBL
InterPro Alkaline_phosphatase_core_sf UniProtKB/TrEMBL
  Phosphodiest/P_Trfase UniProtKB/TrEMBL
NCBI Gene Enpp5 ENTREZGENE
PANTHER ECTONUCLEOTIDE PYROPHOSPHATASE/PHOSPHODIESTERASE UniProtKB/TrEMBL
  ECTONUCLEOTIDE PYROPHOSPHATASE/PHOSPHODIESTERASE FAMILY MEMBER 5 UniProtKB/TrEMBL
Pfam Phosphodiest UniProtKB/TrEMBL
Superfamily-SCOP SSF53649 UniProtKB/TrEMBL
UniProt I3MI62 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2019-03-05 Enpp5  ectonucleotide pyrophosphatase/phosphodiesterase family member 5    ectonucleotide pyrophosphatase/phosphodiesterase 5 (putative)  Symbol and/or name change 5135510 APPROVED