ENPP5 (ectonucleotide pyrophosphatase/phosphodiesterase family member 5) - Rat Genome Database

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Gene: ENPP5 (ectonucleotide pyrophosphatase/phosphodiesterase family member 5) Pan paniscus
Analyze
Symbol: ENPP5
Name: ectonucleotide pyrophosphatase/phosphodiesterase family member 5
RGD ID: 11831534
Description: ENCODES a protein that exhibits NAD+ diphosphatase activity (inferred); zinc ion binding (inferred); INVOLVED IN cell communication (ortholog); ASSOCIATED WITH COVID-19 (ortholog); genetic disease (ortholog); Prostatic Neoplasms (ortholog); FOUND IN plasma membrane (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: ectonucleotide pyrophosphatase/phosphodiesterase 5 (putative)
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly
Position:
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2560,642,891 - 60,664,298 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1656,508,953 - 56,530,294 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0645,735,167 - 45,751,671 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1647,013,701 - 47,025,523 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl647,013,699 - 47,025,523 (-)Ensemblpanpan1.1panPan2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References

Genomics

Comparative Map Data
ENPP5
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2560,642,891 - 60,664,298 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1656,508,953 - 56,530,294 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0645,735,167 - 45,751,671 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1647,013,701 - 47,025,523 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl647,013,699 - 47,025,523 (-)Ensemblpanpan1.1panPan2
ENPP5
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38646,159,185 - 46,170,980 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl646,159,185 - 46,170,980 (-)EnsemblGRCh38hg38GRCh38
GRCh37646,126,922 - 46,138,717 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36646,235,721 - 46,246,676 (-)NCBINCBI36Build 36hg18NCBI36
Build 34646,235,720 - 46,246,676NCBI
Celera647,680,299 - 47,691,261 (-)NCBICelera
Cytogenetic Map6p21.1NCBI
HuRef645,850,807 - 45,861,762 (-)NCBIHuRef
CHM1_1646,131,010 - 46,141,952 (-)NCBICHM1_1
T2T-CHM13v2.0645,994,273 - 46,006,158 (-)NCBIT2T-CHM13v2.0
Enpp5
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391744,389,693 - 44,397,458 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1744,389,704 - 44,397,458 (+)EnsemblGRCm39 Ensembl
GRCm381744,078,802 - 44,086,567 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1744,078,813 - 44,086,567 (+)EnsemblGRCm38mm10GRCm38
MGSCv371744,215,795 - 44,223,516 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361743,541,924 - 43,549,614 (+)NCBIMGSCv36mm8
Celera1747,500,370 - 47,508,072 (+)NCBICelera
Cytogenetic Map17B3NCBI
cM Map1720.3NCBI
Enpp5
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8924,407,574 - 24,415,029 (-)NCBIGRCr8
mRatBN7.2916,910,187 - 16,917,633 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl916,910,831 - 16,917,480 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx925,494,836 - 25,501,470 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0930,569,359 - 30,575,993 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0928,858,569 - 28,865,203 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0919,469,276 - 19,476,684 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl919,469,706 - 19,476,646 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0918,347,773 - 18,355,164 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4912,574,480 - 12,581,130 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1912,571,802 - 12,578,452 (-)NCBI
Celera914,637,055 - 14,643,705 (-)NCBICelera
Cytogenetic Map9q13NCBI
Enpp5
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495543711,195,391 - 11,204,728 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495543711,195,846 - 11,204,000 (-)NCBIChiLan1.0ChiLan1.0
ENPP5
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11214,376,278 - 14,387,883 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1214,377,565 - 14,385,171 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1214,408,235 - 14,419,802 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01214,876,522 - 14,888,437 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1214,877,806 - 14,888,470 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11214,392,730 - 14,404,121 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01214,480,941 - 14,492,536 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01214,577,456 - 14,589,058 (-)NCBIUU_Cfam_GSD_1.0
Enpp5
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494649,781,793 - 49,790,968 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493647614,169,148 - 14,179,151 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493647614,169,298 - 14,178,930 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ENPP5
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl740,920,031 - 40,933,326 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1740,920,030 - 40,936,380 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2747,233,579 - 47,249,978 (+)NCBISscrofa10.2Sscrofa10.2susScr3
ENPP5
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11726,082,427 - 26,091,526 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1726,082,451 - 26,092,900 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604446,165,201 - 46,175,504 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Enpp5
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462475414,286,371 - 14,295,501 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462475414,286,337 - 14,294,529 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts XM_003833209 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide JARIFH020000005 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSPPAT00000041773   ⟹   ENSPPAP00000019025
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl647,013,699 - 47,025,523 (-)Ensembl
RefSeq Acc Id: XM_003833209   ⟹   XP_003833257
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2560,642,891 - 60,664,298 (-)NCBI
NHGRI_mPanPan1656,508,953 - 56,530,294 (-)NCBI
Mhudiblu_PPA_v0645,735,167 - 45,751,671 (-)NCBI
PanPan1.1647,013,701 - 47,025,523 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_003833257 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSPPAP00000019025.1
Reference Protein Sequences
RefSeq Acc Id: XP_003833257   ⟸   XM_003833209
- UniProtKB: A0A2R9ATC0 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSPPAP00000019025   ⟸   ENSPPAT00000041773


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSPPAG00000032683 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSPPAT00000041773.1 UniProtKB/TrEMBL
Gene3D-CATH 3.30.1360.180 UniProtKB/TrEMBL
  3.40.720.10 UniProtKB/TrEMBL
InterPro Alkaline_phosphatase_core_sf UniProtKB/TrEMBL
  Phosphodiest/P_Trfase UniProtKB/TrEMBL
KEGG Report pps:100968817 UniProtKB/TrEMBL
NCBI Gene ENPP5 ENTREZGENE
PANTHER ECTONUCLEOTIDE PYROPHOSPHATASE/PHOSPHODIESTERASE UniProtKB/TrEMBL
  ECTONUCLEOTIDE PYROPHOSPHATASE/PHOSPHODIESTERASE FAMILY MEMBER 5 UniProtKB/TrEMBL
Pfam Phosphodiest UniProtKB/TrEMBL
Superfamily-SCOP SSF53649 UniProtKB/TrEMBL
UniProt A0A2R9ATC0 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2019-03-05 ENPP5  ectonucleotide pyrophosphatase/phosphodiesterase family member 5    ectonucleotide pyrophosphatase/phosphodiesterase 5 (putative)  Symbol and/or name change 5135510 APPROVED