Phkb (phosphorylase kinase regulatory subunit beta) - Rat Genome Database

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Gene: Phkb (phosphorylase kinase regulatory subunit beta) Ictidomys tridecemlineatus
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Symbol: Phkb
Name: phosphorylase kinase regulatory subunit beta
RGD ID: 12668595
Description: ENCODES a protein that exhibits calmodulin binding (inferred); INVOLVED IN glucose homeostasis (ortholog); positive regulation of glycogen catabolic process (ortholog); protein phosphorylation (ortholog); PARTICIPATES IN glycogen degradation pathway; ASSOCIATED WITH genetic disease (ortholog); glycogen storage disease IXB (ortholog); FOUND IN phosphorylase kinase complex (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: phosphorylase b kinase regulatory subunit beta; phosphorylase kinase regulatory subunit beta, transcript variant X1; phosphorylase kinase regulatory subunit beta, transcript variant X2; phosphorylase kinase regulatory subunit beta, transcript variant X3; phosphorylase kinase regulatory subunit beta, transcript variant X4; phosphorylase kinase regulatory subunit beta, transcript variant X5; phosphorylase kinase regulatory subunit beta, transcript variant X6
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: SpeTri2.0 - Squirrel SpeTri2.0 Assembly
Position:
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440934958,586,224 - 58,809,915 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936475779,302 - 1,003,262 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936475779,238 - 1,002,851 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References
Additional References at PubMed
PMID:30032202  


Genomics

Comparative Map Data
Phkb
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440934958,586,224 - 58,809,915 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936475779,302 - 1,003,262 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936475779,238 - 1,002,851 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
PHKB
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381647,461,299 - 47,701,523 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1647,461,123 - 47,701,523 (+)EnsemblGRCh38hg38GRCh38
GRCh371647,495,210 - 47,735,434 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361646,052,739 - 46,291,755 (+)NCBINCBI36Build 36hg18NCBI36
Build 341646,052,738 - 46,291,755NCBI
Celera1632,003,151 - 32,243,373 (+)NCBICelera
Cytogenetic Map16q12.1NCBI
HuRef1633,385,772 - 33,625,996 (+)NCBIHuRef
CHM1_11648,902,240 - 49,142,934 (+)NCBICHM1_1
T2T-CHM13v2.01653,258,117 - 53,498,326 (+)NCBIT2T-CHM13v2.0
Phkb
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39886,567,489 - 86,790,883 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl886,567,588 - 86,788,005 (+)EnsemblGRCm39 Ensembl
GRCm38885,840,853 - 86,064,251 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl885,840,959 - 86,061,376 (+)EnsemblGRCm38mm10GRCm38
MGSCv37888,364,901 - 88,584,541 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36888,731,107 - 88,950,747 (+)NCBIMGSCv36mm8
Celera890,138,260 - 90,352,039 (+)NCBICelera
Cytogenetic Map8C3NCBI
cM Map841.61NCBI
Phkb
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81937,179,937 - 37,383,979 (-)NCBIGRCr8
mRatBN7.21921,013,719 - 21,210,671 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1921,025,733 - 21,210,633 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1922,713,124 - 22,893,420 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01927,907,652 - 28,087,942 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01930,870,462 - 31,050,747 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01922,031,684 - 22,281,788 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1922,033,228 - 22,281,778 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01933,031,043 - 33,289,256 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41922,373,355 - 22,561,509 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11922,378,643 - 22,380,741 (-)NCBI
Celera1920,893,425 - 21,075,361 (-)NCBICelera
Cytogenetic Map19p11NCBI
Phkb
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554747,598,463 - 7,801,083 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554747,599,657 - 7,801,083 (-)NCBIChiLan1.0ChiLan1.0
PHKB
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21856,914,379 - 57,154,821 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11662,819,336 - 63,059,963 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01627,720,300 - 27,960,740 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11646,612,062 - 46,853,157 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1646,612,053 - 46,853,157 (+)Ensemblpanpan1.1panPan2
PHKB
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1267,260,532 - 67,476,596 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl267,254,542 - 67,476,532 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha263,836,201 - 64,052,047 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0267,818,656 - 68,034,694 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl267,818,659 - 68,034,650 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1264,631,779 - 64,847,974 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0265,655,460 - 65,871,221 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0266,543,573 - 66,759,826 (-)NCBIUU_Cfam_GSD_1.0
PHKB
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl636,991,274 - 37,193,593 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1636,994,424 - 37,193,631 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2632,141,368 - 32,246,744 (-)NCBISscrofa10.2Sscrofa10.2susScr3
PHKB
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1533,288,396 - 33,512,445 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl533,291,009 - 33,513,244 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604743,031,736 - 43,259,030 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Phkb
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046249141,013,145 - 1,234,610 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046249141,013,828 - 1,235,023 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression

RNA-SEQ Expression


Sequence


Ensembl Acc Id: ENSSTOT00000007738   ⟹   ENSSTOP00000006925
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
SpeTri2.0 EnsemblNW_004936475781,642 - 1,003,262 (+)Ensembl
Ensembl Acc Id: ENSSTOT00000032391   ⟹   ENSSTOP00000031101
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
SpeTri2.0 EnsemblNW_004936475781,642 - 1,003,262 (+)Ensembl
Ensembl Acc Id: ENSSTOT00000033786   ⟹   ENSSTOP00000028347
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
SpeTri2.0 EnsemblNW_004936475779,302 - 1,003,262 (+)Ensembl
RefSeq Acc Id: XM_005318148   ⟹   XP_005318205
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440934958,586,649 - 58,809,790 (-)NCBI
SpeTri2.0NW_004936475779,258 - 1,002,051 (+)NCBI
Sequence:
RefSeq Acc Id: XM_005318149   ⟹   XP_005318206
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440934958,586,649 - 58,809,915 (-)NCBI
SpeTri2.0NW_004936475779,238 - 1,002,851 (+)NCBI
Sequence:
RefSeq Acc Id: XM_021721160   ⟹   XP_021576835
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440934958,586,649 - 58,809,856 (-)NCBI
SpeTri2.0NW_004936475779,252 - 1,002,310 (+)NCBI
Sequence:
RefSeq Acc Id: XM_021721167   ⟹   XP_021576842
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440934958,587,117 - 58,807,433 (-)NCBI
SpeTri2.0NW_004936475781,687 - 1,002,851 (+)NCBI
Sequence:
RefSeq Acc Id: XM_021721171   ⟹   XP_021576846
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440934958,586,224 - 58,771,804 (-)NCBI
SpeTri2.0NW_004936475817,187 - 1,002,851 (+)NCBI
Sequence:
RefSeq Acc Id: XP_005318205   ⟸   XM_005318148
- Peptide Label: isoform X2
- UniProtKB: A0A287DC84 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_005318206   ⟸   XM_005318149
- Peptide Label: isoform X1
- UniProtKB: A0A287D498 (UniProtKB/TrEMBL),   A0A287DC84 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_021576835   ⟸   XM_021721160
- Peptide Label: isoform X3
- UniProtKB: I3MAB5 (UniProtKB/TrEMBL),   A0A287DC84 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_021576842   ⟸   XM_021721167
- Peptide Label: isoform X4
- UniProtKB: A0A287DC84 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_021576846   ⟸   XM_021721171
- Peptide Label: isoform X5
- UniProtKB: A0A287DC84 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSSTOP00000028347   ⟸   ENSSTOT00000033786
Ensembl Acc Id: ENSSTOP00000031101   ⟸   ENSSTOT00000032391
Ensembl Acc Id: ENSSTOP00000006925   ⟸   ENSSTOT00000007738

Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSTOG00000007705 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSSTOT00000007738.3 UniProtKB/TrEMBL
  ENSSTOT00000032391.1 UniProtKB/TrEMBL
  ENSSTOT00000033786.1 UniProtKB/TrEMBL
InterPro 6-hairpin_glycosidase_sf UniProtKB/TrEMBL
  GH15-like UniProtKB/TrEMBL
  KPBA/B_C UniProtKB/TrEMBL
  PHK_A/B_su UniProtKB/TrEMBL
NCBI Gene Phkb ENTREZGENE
PANTHER PHOSPHORYLASE B KINASE REGULATORY SUBUNIT BETA UniProtKB/TrEMBL
  PTHR10749 UniProtKB/TrEMBL
Pfam Glyco_hydro_15 UniProtKB/TrEMBL
  KPBB_C UniProtKB/TrEMBL
Superfamily-SCOP SSF48208 UniProtKB/TrEMBL
UniProt A0A287D498 ENTREZGENE, UniProtKB/TrEMBL
  A0A287DC84 ENTREZGENE, UniProtKB/TrEMBL
  I3MAB5 ENTREZGENE, UniProtKB/TrEMBL