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Gene: Trib1 (tribbles pseudokinase 1) Ictidomys tridecemlineatus

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Symbol:

Trib1

Name:

tribbles pseudokinase 1

RGD ID:

12662117

Description:

ENCODES a protein that exhibits transcription regulator inhibitor activity (ortholog); INVOLVED IN negative regulation of DNA-binding transcription factor activity (ortholog); negative regulation of JNK cascade (ortholog); regulation of MAP kinase activity (ortholog); ASSOCIATED WITH coronary artery disease (ortholog); Hypertriglyceridemia (ortholog); metabolic dysfunction-associated steatotic liver disease (ortholog); FOUND IN cytoplasm (inferred); nucleus (inferred)

Type:

protein-coding

RefSeq Status:

MODEL

Previously known as:

tribbles homolog 1

RGD Orthologs

Alliance Orthologs

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	TRIB1 (tribbles pseudokinase 1)	NCBI	Ortholog
Mus musculus (house mouse):	Trib1 (tribbles pseudokinase 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Rattus norvegicus (Norway rat):	Trib1 (tribbles pseudokinase 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Trib1 (tribbles pseudokinase 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	TRIB1 (tribbles pseudokinase 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	TRIB1 (tribbles pseudokinase 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	TRIB1 (tribbles pseudokinase 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	TRIB1 (tribbles pseudokinase 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Trib1 (tribbles pseudokinase 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline

Latest Assembly:

SpeTri2.0 - Squirrel SpeTri2.0 Assembly

Position:

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024405303	14,975,282 - 14,983,509 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936470	22,401,379 - 22,409,490 (-)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936470	22,401,713 - 22,408,808 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Only show annotations with direct experimental evidence (0 objects hidden)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
Trib1	Squirrel	Hypertriglyceridemia	susceptibility	ISO	RGD:1354037	9068941	DNA:SNPs,haplotypes: (rs6982502) (human)	RGD	PMID:27599772\|REF_RGD_ID:401794577

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
Trib1	Squirrel	trichorhinophalangeal syndrome type I		ISO	RGD:1354037	8554872	ClinVar Annotator: match by term: Trichorhinophalangeal dysplasia type I	ClinVar	PMID:25741868

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
Trib1	Squirrel	coronary artery disease		ISO	RGD:1354037	9068941	CTD Direct Evidence: marker/mechanism	CTD	PMID:24097064
Trib1	Squirrel	metabolic dysfunction-associated steatotic liver disease		ISO	RGD:1354037	9068941	CTD Direct Evidence: marker/mechanism	CTD	PMID:35654975

Biological Process

Only show annotations with direct experimental evidence (0 objects hidden)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
Trib1	Squirrel	JNK cascade	involved_in	IEA	UniProtKB:Q96RU8\|ensembl:ENSP00000312150	150520179		Ensembl	GO_REF:0000107
Trib1	Squirrel	negative regulation of DNA-binding transcription factor activity	involved_in	ISO	RGD:1332442	9068941	PMID:17724128	BHF-UCL	PMID:17724128
Trib1	Squirrel	negative regulation of JNK cascade	involved_in	ISO	RGD:1354037	9068941	PMID:17452330	BHF-UCL	PMID:17452330
Trib1	Squirrel	negative regulation of lipopolysaccharide-mediated signaling pathway	involved_in	IEA	UniProtKB:Q96RU8\|ensembl:ENSP00000312150	150520179		Ensembl	GO_REF:0000107
Trib1	Squirrel	negative regulation of MAPK cascade	involved_in	IEA	UniProtKB:Q96RU8\|ensembl:ENSP00000312150	150520179		Ensembl	GO_REF:0000107
Trib1	Squirrel	negative regulation of neutrophil differentiation	involved_in	IEA	UniProtKB:Q8K4K4\|ensembl:ENSMUSP00000068834	150520179		Ensembl	GO_REF:0000107
Trib1	Squirrel	negative regulation of smooth muscle cell migration	involved_in	IEA	UniProtKB:Q96RU8\|ensembl:ENSP00000312150	150520179		Ensembl	GO_REF:0000107
Trib1	Squirrel	negative regulation of smooth muscle cell proliferation	involved_in	IEA	UniProtKB:Q96RU8\|ensembl:ENSP00000312150	150520179		Ensembl	GO_REF:0000107
Trib1	Squirrel	positive regulation of eosinophil differentiation	involved_in	IEA	UniProtKB:Q8K4K4\|ensembl:ENSMUSP00000068834	150520179		Ensembl	GO_REF:0000107
Trib1	Squirrel	positive regulation of macrophage differentiation	involved_in	IEA	UniProtKB:Q8K4K4\|ensembl:ENSMUSP00000068834	150520179		Ensembl	GO_REF:0000107
Trib1	Squirrel	positive regulation of proteasomal ubiquitin-dependent protein catabolic process	involved_in	IEA	PANTHER:PTN001884184	150520179		TreeGrafter	GO_REF:0000118
Trib1	Squirrel	positive regulation of proteasomal ubiquitin-dependent protein catabolic process	involved_in	IEA	UniProtKB:Q8K4K4\|ensembl:ENSMUSP00000068834	150520179		Ensembl	GO_REF:0000107
Trib1	Squirrel	regulation of MAP kinase activity	involved_in	ISO	RGD:1354037	9068941	PMID:15299019	UniProt	PMID:15299019
Trib1	Squirrel	response to lipopolysaccharide	involved_in	IEA	UniProtKB:Q8K4K4\|UniProtKB:Q96RU8\|ensembl:ENSMUSP00000068834\|ensembl:ENSP00000312150	150520179		Ensembl	GO_REF:0000107

Cellular Component

Only show annotations with direct experimental evidence (0 objects hidden)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
Trib1	Squirrel	cytoplasm	located_in	IEA	UniProtKB:Q96RU8\|ensembl:ENSP00000312150	150520179		Ensembl	GO_REF:0000107
Trib1	Squirrel	nucleus	located_in	IEA	UniProtKB:Q96RU8\|ensembl:ENSP00000312150	150520179		Ensembl	GO_REF:0000107
Trib1	Squirrel	nucleus	located_in	IEA	PANTHER:PTN001884184	150520179		TreeGrafter	GO_REF:0000118

Molecular Function

Only show annotations with direct experimental evidence (0 objects hidden)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
Trib1	Squirrel	ATP binding	enables	IEA	InterPro:IPR000719	150520179		InterPro	GO_REF:0000002
Trib1	Squirrel	mitogen-activated protein kinase kinase binding	enables	IEA	PANTHER:PTN001884184	150520179		TreeGrafter	GO_REF:0000118
Trib1	Squirrel	mitogen-activated protein kinase kinase binding	enables	IEA	UniProtKB:Q96RU8\|ensembl:ENSP00000312150	150520179		Ensembl	GO_REF:0000107
Trib1	Squirrel	protein binding	enables	ISO	UniProtKB:Q8N2I9	9068941	PMID:25852190, PMID:28514442, PMID:32707033, PMID:33961781	IntAct	PMID:25852190\|PMID:28514442\|PMID:32707033\|PMID:33961781
Trib1	Squirrel	protein binding	enables	ISO	UniProtKB:P49715-1	9068941	PMID:26455797	IntAct	PMID:26455797
Trib1	Squirrel	protein kinase activity	enables	IEA	InterPro:IPR000719	150520179		InterPro	GO_REF:0000002
Trib1	Squirrel	protein kinase binding	enables	IEA	UniProtKB:Q96RU8\|ensembl:ENSP00000312150	150520179		Ensembl	GO_REF:0000107
Trib1	Squirrel	protein kinase inhibitor activity	enables	IEA	UniProtKB:Q96RU8\|ensembl:ENSP00000312150	150520179		Ensembl	GO_REF:0000107
Trib1	Squirrel	RNA polymerase II-specific DNA-binding transcription factor binding	enables	IEA	UniProtKB:Q8K4K4\|UniProtKB:Q96RU8\|ensembl:ENSMUSP00000068834\|ensembl:ENSP00000312150	150520179		Ensembl	GO_REF:0000107
Trib1	Squirrel	transcription regulator inhibitor activity	enables	ISO	RGD:1354037	9068941	PMID:17724128	BHF-UCL	PMID:17724128
Trib1	Squirrel	ubiquitin protein ligase binding	enables	IEA	UniProtKB:Q8K4K4\|ensembl:ENSMUSP00000068834	150520179		Ensembl	GO_REF:0000107
Trib1	Squirrel	ubiquitin-protein transferase regulator activity	enables	IEA	UniProtKB:Q8K4K4\|ensembl:ENSMUSP00000068834	150520179		Ensembl	GO_REF:0000107

PMID:22301074	PMID:30032202

Trib1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024405303	14,975,282 - 14,983,509 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936470	22,401,379 - 22,409,490 (-)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936470	22,401,713 - 22,408,808 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

TRIB1
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	8	125,430,358 - 125,438,403 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	8	125,430,358 - 125,438,403 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	8	126,442,600 - 126,450,645 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	8	126,511,745 - 126,519,827 (+)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	8	126,511,744 - 126,519,824	NCBI
Celera	8	122,631,533 - 122,639,615 (+)	NCBI		Celera
Cytogenetic Map	8	q24.13	NCBI
HuRef	8	121,766,406 - 121,774,484 (+)	NCBI		HuRef
CHM1_1	8	126,482,807 - 126,490,884 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	8	126,563,804 - 126,571,849 (+)	NCBI		T2T-CHM13v2.0

Trib1
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	15	59,520,503 - 59,528,948 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	15	59,520,199 - 59,528,948 (+)	Ensembl		GRCm39 Ensembl
GRCm38	15	59,648,654 - 59,657,099 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	15	59,648,350 - 59,657,099 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	15	59,480,209 - 59,488,654 (+)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	15	59,478,335 - 59,486,780 (+)	NCBI		MGSCv36	mm8
Celera	15	61,178,271 - 61,186,716 (+)	NCBI		Celera
Cytogenetic Map	15	D1	NCBI
cM Map	15	25.41	NCBI

Trib1
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	7	93,096,001 - 93,102,547 (+)	NCBI		GRCr8
mRatBN7.2	7	91,206,579 - 91,213,126 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	7	91,206,579 - 91,214,731 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	7	93,092,395 - 93,098,946 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	7	95,293,606 - 95,300,157 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	7	95,125,539 - 95,132,086 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	7	99,954,492 - 99,961,026 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	7	99,954,492 - 99,961,026 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	7	100,534,391 - 100,540,925 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	7	96,442,239 - 96,448,785 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	7	96,477,093 - 96,482,772 (+)	NCBI
Celera	7	87,967,385 - 87,973,931 (+)	NCBI		Celera
Cytogenetic Map	7	q33	NCBI

Trib1
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955461	494,003 - 501,990 (+)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955461	494,003 - 501,928 (+)	NCBI	ChiLan1.0	ChiLan1.0

TRIB1
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	7	142,852,443 - 142,860,884 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	8	118,364,202 - 118,371,720 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	8	122,115,194 - 122,123,319 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	8	124,867,334 - 124,874,863 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	8	124,867,359 - 124,872,924 (+)	Ensembl	panpan1.1		panPan2

TRIB1
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	13	23,337,788 - 23,346,304 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	13	23,337,788 - 23,346,304 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	13	23,310,655 - 23,319,064 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	13	23,683,492 - 23,691,935 (+)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	13	23,682,916 - 23,691,935 (+)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	13	23,404,842 - 23,413,262 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	13	23,511,711 - 23,520,081 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	13	23,755,679 - 23,764,091 (+)	NCBI		UU_Cfam_GSD_1.0

TRIB1
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	4	14,289,751 - 14,297,663 (-)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	4	14,289,739 - 14,298,119 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1

TRIB1
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	8	120,013,757 - 120,021,823 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	8	120,014,339 - 120,019,887 (+)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666039	20,151,213 - 20,159,305 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Trib1
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624735	29,879,310 - 29,888,305 (-)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624735	29,880,732 - 29,888,117 (-)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.


RefSeq Transcripts	XM_005316159	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	JAESOR010000362	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSSTOT00000023063 ⟹ ENSSTOP00000015980

Type:

CODING

Position:

Squirrel Assembly	Chr	Position (strand)	Source
SpeTri2.0 Ensembl	NW_004936470	22,401,379 - 22,409,490 (-)	Ensembl

RefSeq Acc Id:

XM_005316159 ⟹ XP_005316216

Type:

CODING

Position:

Squirrel Assembly	Chr	Position (strand)	Source
HiC_Itri_2	NW_024405303	14,975,282 - 14,983,509 (-)	NCBI
SpeTri2.0	NW_004936470	22,401,713 - 22,408,808 (-)	NCBI

Sequence:

show sequence

CGGGCTGGAAGGAGTCGCAGCGCCGGCGTCAAGCCCGAAGCACCTTCCTGAGCAGAGCAGGGGACGTACGAAGCCGGGGCCGCCCTGGCCGCGGACGCGATGAGGGTTGGCCCCGTGCGCTCTGCCAT
GAGCGGCGCCTCGCAGCCCGGCGGTCCGGCCCTGCTCCTCCCGGCCACTCGGGGCAATCCAGCCAAACGCCTGCTGGACGCCGACGACGCGGCGGCGGTGGCTGCCAAGTGCCCGCGCCTCTCGGAGT
GCTCCAGTCCCCCGGACTACCTCAGCCCCCCCGGCTCGCCCTGCAGCCCACAGCCCCCTCCTACCGCTCCAGGGGCCGGCGGCGGCTCCGGGAGCGCACCGGGGCCCAGCCGCATAGCCGACTACCTG
CTGCTGCCCCTAGCCGAGCGCGAGCATGTGTCCCGGGCGCTTTGCATCCACACCGGCCGCGAGCTGCGCTGCAAGGTGTTTCCCATTAAACACTACCAGGACAAAATCAGGCCTTACATCCAGCTGCC
ATCGCACAGGAACATCACTGGCATCGTGGAAGTGATACTTGGGGAAACCAAGGCCTACGTGTTCTTCGAGAGAGACTTTGGGGACATGCACTCCTATGTGCGAAGCCGGAAGAGGCTGCGGGAAGAGG
AGGCTGCCCGGCTCTTCAAGCAGATTGTGTCCGCCGTGGCCCACTGCCACCAGTCGGCTATTGTGCTGGGGGACCTGAAGCTTAGGAAGTTCGTCTTCTCCACGGGGGAGAGAACCCAGCTCCGACTG
GAAAGTCTGGAAGATACGCACATCATCAAGGGCGAAGATGATGCTTTGTCAGACAAGCATGGCTGCCCAGCTTACGTGAGCCCCGAGATCCTCAACACCACCGGGACCTACTCCGGAAAGGCGGCGGA
CGTTTGGAGCCTCGGGGTGATGCTCTACACCCTTTTGGTCGGACGATACCCCTTCCATGACTCGGACCCTAGTGCTCTCTTCTCCAAAATCCGACGCGGACAGTTCTGCATTCCCGACCACATTTCCC
CCAAAGCCAGGTGCCTCATTCGCAGCCTCCTGAGACGGGAGCCTTCCGAGAGACTCACTGCTCCTGAGATCTTACTCCATCCCTGGTTTGAGTCTGCCCTGGAGCCTGGGTACGTTGACTCAGAAATA
GGAACTTCAGACCAGATTGTTCCAGAGTACGAGGAGGACAGTGACATGAGTTCCTTCTTCTGCTAATCCCAAAAACCTCAGAAACCTCATAATTCTCACTCATGGCATTTCCATTTCTCAAGATGGAC
GGGCCCCTCTGGCACGGTGCCAGCCAGAAGTCCGGACGGAGGGCACCAAGGTTGTCTCCGCAGAACTCACCGTGGAACCCTGTCTCACAGTGGGGGAGGAGCGACTGTTGATTTGAGCAGCACGACCC
TCTGACTTAACTGCAGAGTCGTTCCCTTCTTTACCAACTACCCTCAACTCTGTCTTTGTCAGATCTGGGGCGTTCTGTGTCTTTCAAAGGTGGCAAAGAGGGTAGCGTGGACATCCCACGCTGTGTGG
TCAAGTGTCATGAACTTGAACATTCACATGGGAAAGGCAGGAAGTCACCCAGTGGCATTTTGGGCAATAACCATGTTTTAATGGGGTGGCAGATCACTTGGGTCAATAAGCCTGCCATCTTAGAAAAA
AACTCCTTCGTAGCTGGACTTGTCGCTGCAGTTTCTCCCATCAGAAAGCCCGCTCTTGCTCTTGGTTTGTTGCGACATCTGTCTTTGCCTCATGGTCACACTTAACCAACAACTCTGCTCTGTTGTCT
GAGCAGACTGAGGAGCTCAGGAGCCTGCCTGAACCCTGACCCTACTCTACTCCTGCCCTGCTCCCATCTCACATGCAATAATGCCTTGTCCTTGACCTTGAAACTTGCCCCCTGCAGCTATGAAAGTA
CTTGCCAGCTAATCGTTGAAAAGTGCAGAAAAAATGCGGAACTCTTGGCTATTTCAGAACTCTGAGCTCCAGTAGAGACTGCCATTAAAAAACAAACAAAAAAACCAATTTGATCACTTGGAAACCTT
TGGCATTTTCAGTTTCCTTCTAGTGTGCTGGGGCTTAGCCTTTAATTTTCCCCCCACAAGATCTCAGGGTGGAACATGTTGTCCAGGAAGAGAAAGGAGACTCCCCACCCTGCTCTCCCAGGAGCAAA
GGGTAAACCTCTTTGTGCTTTAAAGAAAGTGAATTTTGGACAGCATTAGGATTCCCAGACTAAGTTCCAGAATGATACTGTGCCCCGCCCTGTGTGGGCATCCTGGGTGCACTTGGGGTTTTGCGAGG
TGGGTTGTTGGTACAAGTGGTGTGGTCTCTGACTACACATCTGTGCAGCCGGCTGCTGGGGTGGAATAGTGAGCCCCCAGGTATTTCAAGTTGGAAGGACTTTGACAATCATCCGATCCAACTTCTCC
TCGCTGCCACCTCCCACTGCAGAAATCCTCACCTTCAGCTTCTTTCCCAGGTGAGAATCCAACCTCTGTTTGAATGCTTCTAGAGACAGAAACTCACTCCCTACAAAAGGTAGAACTTCACGGAGAGA
CTGCAACTTGCATTAAAAAACAAGGACAGATGAAGAGTCAGTCGCTGTCTCAGACGGTGCCGAAATCAGGTGGATAAACGGGTAAACAAATATACTGTATTTGAAGAAATGGCACAAACCAGGCAGGC
ATCTTCAAGGGCTACGCCTACGCGAACTACTAACCTGCATTGTAAGAATGCTGTGTATACCTCATGTACTGTGTACTCTGTACATATATTTTACCTTTTATACCTA

hide sequence


Protein RefSeqs	XP_005316216	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSSTOP00000015980.1
GenBank Protein	KAG3273620	(Get FASTA)	NCBI Sequence Viewer

RefSeq Acc Id:

XP_005316216 ⟸ XM_005316159

- UniProtKB:

I3MV35 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MRVGPVRSAMSGASQPGGPALLLPATRGNPAKRLLDADDAAAVAAKCPRLSECSSPPDYLSPPGSPCSPQPPPTAPGAGGGSGSAPGPSRIADYLLLPLAEREHVSRALCIHTGRELRCKVFPIKHYQ
DKIRPYIQLPSHRNITGIVEVILGETKAYVFFERDFGDMHSYVRSRKRLREEEAARLFKQIVSAVAHCHQSAIVLGDLKLRKFVFSTGERTQLRLESLEDTHIIKGEDDALSDKHGCPAYVSPEILNT
TGTYSGKAADVWSLGVMLYTLLVGRYPFHDSDPSALFSKIRRGQFCIPDHISPKARCLIRSLLRREPSERLTAPEILLHPWFESALEPGYVDSEIGTSDQIVPEYEEDSDMSSFFC

hide sequence

Ensembl Acc Id:

ENSSTOP00000015980 ⟸ ENSSTOT00000023063

Protein Domains

Protein kinase

Database	Acc Id	Source(s)
Ensembl Genes	ENSSTOG00000023120	Ensembl, UniProtKB/TrEMBL
Ensembl Transcript	ENSSTOT00000023063.2	UniProtKB/TrEMBL
Gene3D-CATH	Phosphorylase Kinase, domain 1	UniProtKB/TrEMBL
	Transferase(Phosphotransferase) domain 1	UniProtKB/TrEMBL
InterPro	Kinase-like_dom_sf	UniProtKB/TrEMBL
	Prot_kinase_dom	UniProtKB/TrEMBL
	TRB1	UniProtKB/TrEMBL
	Tribbles/Ser_Thr_kinase_40	UniProtKB/TrEMBL
NCBI Gene	Trib1	ENTREZGENE
PANTHER	PTHR22961	UniProtKB/TrEMBL
	PTHR22961:SF17	UniProtKB/TrEMBL
Pfam	Pkinase	UniProtKB/TrEMBL
PROSITE	PROTEIN_KINASE_DOM	UniProtKB/TrEMBL
SMART	S_TKc	UniProtKB/TrEMBL
Superfamily-SCOP	SSF56112	UniProtKB/TrEMBL
UniProt	I3MV35	ENTREZGENE, UniProtKB/TrEMBL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailable


InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailable


Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
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MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable

Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD

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Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD