Trib1 (tribbles pseudokinase 1) - Rat Genome Database

Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Gene: Trib1 (tribbles pseudokinase 1) Chinchilla lanigera
Analyze
Symbol: Trib1
Name: tribbles pseudokinase 1
RGD ID: 8883480
Description: ENCODES a protein that exhibits mitogen-activated protein kinase kinase binding (ortholog); protein kinase inhibitor activity (ortholog); RNA polymerase II-specific DNA-binding transcription factor binding (ortholog); INVOLVED IN JNK cascade (ortholog); negative regulation of lipopolysaccharide-mediated signaling pathway (ortholog); negative regulation of neutrophil differentiation (ortholog); ASSOCIATED WITH coronary artery disease (ortholog); genetic disease (ortholog); Hypertriglyceridemia (ortholog); FOUND IN cytoplasm (ortholog); nucleus (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: tribbles homolog 1
RGD Orthologs
Human
Mouse
Rat
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: ChiLan1.0 - Chinchilla ChiLan1.0 Assembly
Position:
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_004955461494,003 - 501,990 (+)EnsemblChiLan1.0
ChiLan1.0NW_004955461494,003 - 501,928 (+)NCBIChiLan1.0ChiLan1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


References

References - curated
# Reference Title Reference Citation
1. Transitive Annotation Pipeline Automated assignment of GO, PW and RDO ISO annotations across species
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Trib1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_004955461494,003 - 501,990 (+)EnsemblChiLan1.0
ChiLan1.0NW_004955461494,003 - 501,928 (+)NCBIChiLan1.0ChiLan1.0
TRIB1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh388125,430,358 - 125,438,403 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl8125,430,358 - 125,438,403 (+)EnsemblGRCh38hg38GRCh38
GRCh378126,442,600 - 126,450,645 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 368126,511,745 - 126,519,827 (+)NCBINCBI36Build 36hg18NCBI36
Build 348126,511,744 - 126,519,824NCBI
Celera8122,631,533 - 122,639,615 (+)NCBICelera
Cytogenetic Map8q24.13NCBI
HuRef8121,766,406 - 121,774,484 (+)NCBIHuRef
CHM1_18126,482,807 - 126,490,884 (+)NCBICHM1_1
T2T-CHM13v2.08126,563,804 - 126,571,849 (+)NCBIT2T-CHM13v2.0
Trib1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391559,520,503 - 59,528,948 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1559,520,199 - 59,528,948 (+)EnsemblGRCm39 Ensembl
GRCm381559,648,654 - 59,657,099 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1559,648,350 - 59,657,099 (+)EnsemblGRCm38mm10GRCm38
MGSCv371559,480,209 - 59,488,654 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361559,478,335 - 59,486,780 (+)NCBIMGSCv36mm8
Celera1561,178,271 - 61,186,716 (+)NCBICelera
Cytogenetic Map15D1NCBI
cM Map1525.41NCBI
Trib1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8793,096,001 - 93,102,547 (+)NCBIGRCr8
mRatBN7.2791,206,579 - 91,213,126 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl791,206,579 - 91,214,731 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx793,092,395 - 93,098,946 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0795,293,606 - 95,300,157 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0795,125,539 - 95,132,086 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0799,954,492 - 99,961,026 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl799,954,492 - 99,961,026 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.07100,534,391 - 100,540,925 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4796,442,239 - 96,448,785 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1796,477,093 - 96,482,772 (+)NCBI
Celera787,967,385 - 87,973,931 (+)NCBICelera
Cytogenetic Map7q33NCBI
TRIB1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v27142,852,443 - 142,860,884 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan18118,364,202 - 118,371,720 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v08122,115,194 - 122,123,319 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.18124,867,334 - 124,874,863 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl8124,867,359 - 124,872,924 (+)Ensemblpanpan1.1panPan2
TRIB1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11323,337,788 - 23,346,304 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1323,337,788 - 23,346,304 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1323,310,655 - 23,319,064 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01323,683,492 - 23,691,935 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1323,682,916 - 23,691,935 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11323,404,842 - 23,413,262 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01323,511,711 - 23,520,081 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01323,755,679 - 23,764,091 (+)NCBIUU_Cfam_GSD_1.0
Trib1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440530314,975,282 - 14,983,509 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493647022,401,379 - 22,409,490 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493647022,401,713 - 22,408,808 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
TRIB1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl414,289,751 - 14,297,663 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1414,289,739 - 14,298,119 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
TRIB1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.18120,013,757 - 120,021,823 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl8120,014,339 - 120,019,887 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366603920,151,213 - 20,159,305 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Trib1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462473529,879,310 - 29,888,305 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462473529,880,732 - 29,888,117 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence


RefSeq Acc Id: ENSCLAT00000002854   ⟹   ENSCLAP00000002798
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0 EnsemblNW_004955461494,003 - 501,990 (+)Ensembl
RefSeq Acc Id: XM_005397987   ⟹   XP_005398044
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_004955461494,003 - 501,928 (+)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_005398044 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSCLAP00000002798
  ENSCLAP00000002798.1
RefSeq Acc Id: XP_005398044   ⟸   XM_005397987
- UniProtKB: A0A8C2UQG0 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSCLAP00000002798   ⟸   ENSCLAT00000002854
Protein Domains
Protein kinase


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCLAG00000002016 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCLAT00000002854 ENTREZGENE
  ENSCLAT00000002854.1 UniProtKB/TrEMBL
Gene3D-CATH Transferase(Phosphotransferase) domain 1 UniProtKB/TrEMBL
InterPro Kinase-like_dom_sf UniProtKB/TrEMBL
  Prot_kinase_dom UniProtKB/TrEMBL
  TRB1 UniProtKB/TrEMBL
  Tribbles/Ser_Thr_kinase_40 UniProtKB/TrEMBL
NCBI Gene Trib1 ENTREZGENE
PANTHER PTHR22961 UniProtKB/TrEMBL
  PTHR22961:SF17 UniProtKB/TrEMBL
Pfam Pkinase UniProtKB/TrEMBL
PROSITE PROTEIN_KINASE_DOM UniProtKB/TrEMBL
SMART S_TKc UniProtKB/TrEMBL
Superfamily-SCOP SSF56112 UniProtKB/TrEMBL
UniProt A0A8C2UQG0 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2015-08-25 Trib1  tribbles pseudokinase 1    tribbles homolog 1 (Drosophila)  Symbol and/or name change 5135510 APPROVED