Advanced Search (OLGA)

Gene: Nkx6-1 (NK6 homeobox 1) Ictidomys tridecemlineatus

Subscribe to Updates

Analyze

Symbol:

Nkx6-1

Name:

NK6 homeobox 1

RGD ID:

12600148

Description:

ENCODES a protein that exhibits chromatin binding (ortholog); DNA-binding transcription factor activity (ortholog); DNA-binding transcription repressor activity, RNA polymerase II-specific (ortholog); INVOLVED IN cellular response to cytokine stimulus (ortholog); cellular response to peptide hormone stimulus (ortholog); central nervous system neuron differentiation (ortholog); ASSOCIATED WITH chromosome 4q21 deletion syndrome (ortholog); Experimental Diabetes Mellitus (ortholog); Spinal Cord Injuries (ortholog); FOUND IN nucleus (inferred)

Type:

protein-coding

RefSeq Status:

MODEL

Previously known as:

homeobox protein Nkx-6.1

RGD Orthologs

Alliance Orthologs

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	NKX6-1 (NK6 homeobox 1)	NCBI	Ortholog
Mus musculus (house mouse):	Nkx6-1 (NK6 homeobox 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Rattus norvegicus (Norway rat):	Nkx6-1 (NK6 homeobox 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Nkx6-1 (NK6 homeobox 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	NKX6-1 (NK6 homeobox 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	NKX6-1 (NK6 homeobox 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	NKX6-1 (NK6 homeobox 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	NKX6-1 (NK6 homeobox 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Nkx6-1 (NK6 homeobox 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline

Latest Assembly:

SpeTri2.0 - Squirrel SpeTri2.0 Assembly

Position:

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024405285	4,155,070 - 4,162,340 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936738	317,907 - 324,235 (+)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936738	318,020 - 322,869 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Only show annotations with direct experimental evidence (0 objects hidden)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
Nkx6-1	Squirrel	Spinal Cord Injuries		ISO	Nkx6-1 (Rattus norvegicus)	9068941		RGD	PMID:18687784 and REF_RGD_ID:2311166

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
Nkx6-1	Squirrel	chromosome 4q21 deletion syndrome		ISO	NKX6-1 (Homo sapiens)	8554872	ClinVar Annotator: match by term: Chromosome 4q21 deletion syndrome	ClinVar

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
Nkx6-1	Squirrel	Experimental Diabetes Mellitus		ISO	NKX6-1 (Homo sapiens)	9068941	CTD Direct Evidence: marker/mechanism	CTD	PMID:16123366
Nkx6-1	Squirrel	type 2 diabetes mellitus		ISO	NKX6-1 (Homo sapiens)	9068941	CTD Direct Evidence: marker/mechanism	CTD	PMID:16123366

Biological Process

Only show annotations with direct experimental evidence (0 objects hidden)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
Nkx6-1	Squirrel	cell differentiation	involved_in	IEA	PANTHER:PTN004692492	150520179		TreeGrafter	GO_REF:0000118
Nkx6-1	Squirrel	cellular response to cytokine stimulus		ISO	Nkx6-1 (Rattus norvegicus)	9068941		RGD	PMID:16948396 and REF_RGD_ID:2298711
Nkx6-1	Squirrel	cellular response to peptide hormone stimulus		ISO	Nkx6-1 (Rattus norvegicus)	9068941	prolactin	RGD	PMID:20304194 and REF_RGD_ID:2326021
Nkx6-1	Squirrel	central nervous system neuron differentiation	acts_upstream_of_or_within	ISO	MGI:2386119	9068941	PMID:19592574	MGI	PMID:19592574
Nkx6-1	Squirrel	central nervous system neuron differentiation	acts_upstream_of	IEA	UniProtKB:Q99MA9 and ensembl:ENSMUSP00000042716	150520179		Ensembl	GO_REF:0000107
Nkx6-1	Squirrel	endocrine pancreas development	acts_upstream_of_or_within	IEA	UniProtKB:Q99MA9 and ensembl:ENSMUSP00000042716	150520179		Ensembl	GO_REF:0000107
Nkx6-1	Squirrel	negative regulation of oligodendrocyte differentiation	acts_upstream_of_or_within	IEA	UniProtKB:Q99MA9 and ensembl:ENSMUSP00000042716	150520179		Ensembl	GO_REF:0000107
Nkx6-1	Squirrel	negative regulation of transcription by RNA polymerase II	involved_in	ISO	Nkx6-1 (Rattus norvegicus)	9068941	PMID:15883383	NTNU_SB	PMID:15883383 and REF_RGD_ID:2306242
Nkx6-1	Squirrel	neurogenesis		ISO	Nkx6-1 (Rattus norvegicus)	9068941		RGD	PMID:18687784 and REF_RGD_ID:2311166
Nkx6-1	Squirrel	neuron differentiation	acts_upstream_of	IEA	UniProtKB:Q99MA9 and ensembl:ENSMUSP00000042716	150520179		Ensembl	GO_REF:0000107
Nkx6-1	Squirrel	oligodendrocyte differentiation	acts_upstream_of_or_within	ISO	MGI:1352738	9068941	PMID:15629701	MGI	PMID:15629701
Nkx6-1	Squirrel	oligodendrocyte differentiation	acts_upstream_of	IEA	UniProtKB:Q99MA9 and ensembl:ENSMUSP00000042716	150520179		Ensembl	GO_REF:0000107
Nkx6-1	Squirrel	pancreatic A cell differentiation	acts_upstream_of_or_within	IEA	UniProtKB:Q99MA9 and ensembl:ENSMUSP00000042716	150520179		Ensembl	GO_REF:0000107
Nkx6-1	Squirrel	positive regulation of insulin secretion		ISO	Nkx6-1 (Rattus norvegicus)	9068941		RGD	PMID:15883383 and REF_RGD_ID:2306242
Nkx6-1	Squirrel	positive regulation of neuron differentiation	acts_upstream_of_or_within	IEA	UniProtKB:Q99MA9 and ensembl:ENSMUSP00000042716	150520179		Ensembl	GO_REF:0000107
Nkx6-1	Squirrel	positive regulation of oligodendrocyte differentiation	acts_upstream_of_or_within	IEA	UniProtKB:Q99MA9 and ensembl:ENSMUSP00000042716	150520179		Ensembl	GO_REF:0000107
Nkx6-1	Squirrel	regulation of axon extension	acts_upstream_of_or_within	IEA	UniProtKB:Q99MA9 and ensembl:ENSMUSP00000042716	150520179		Ensembl	GO_REF:0000107
Nkx6-1	Squirrel	regulation of DNA-templated transcription	involved_in	IEA	InterPro:IPR017970	150520179		InterPro	GO_REF:0000002
Nkx6-1	Squirrel	regulation of neuron migration	acts_upstream_of_or_within	IEA	UniProtKB:Q99MA9 and ensembl:ENSMUSP00000042716	150520179		Ensembl	GO_REF:0000107
Nkx6-1	Squirrel	regulation of transcription by RNA polymerase II	acts_upstream_of_or_within	IEA	UniProtKB:Q99MA9 and ensembl:ENSMUSP00000042716	150520179		Ensembl	GO_REF:0000107
Nkx6-1	Squirrel	regulation of transcription by RNA polymerase II	involved_in	IEA	PANTHER:PTN004692492	150520179		TreeGrafter	GO_REF:0000118
Nkx6-1	Squirrel	response to nicotine		ISO	Nkx6-1 (Rattus norvegicus)	9068941		RGD	PMID:18687784 and REF_RGD_ID:2311166
Nkx6-1	Squirrel	response to xenobiotic stimulus		ISO	Nkx6-1 (Rattus norvegicus)	9068941	diazoxide	RGD	PMID:17229937 and REF_RGD_ID:2326024
Nkx6-1	Squirrel	response to xenobiotic stimulus		ISO	Nkx6-1 (Rattus norvegicus)	9068941	troglitazone	RGD	PMID:17192469 and REF_RGD_ID:2311229
Nkx6-1	Squirrel	smoothened signaling pathway	acts_upstream_of_or_within	IEA	UniProtKB:Q99MA9 and ensembl:ENSMUSP00000042716	150520179		Ensembl	GO_REF:0000107
Nkx6-1	Squirrel	transcription by RNA polymerase II		ISO	Nkx6-1 (Rattus norvegicus)	9068941		RGD	PMID:15883383 and REF_RGD_ID:2306242
Nkx6-1	Squirrel	type B pancreatic cell development		ISO	Nkx6-1 (Rattus norvegicus)	9068941		RGD	PMID:9603781 and REF_RGD_ID:2326025
Nkx6-1	Squirrel	type B pancreatic cell differentiation	acts_upstream_of_or_within	IEA	UniProtKB:Q99MA9 and ensembl:ENSMUSP00000042716	150520179		Ensembl	GO_REF:0000107
Nkx6-1	Squirrel	type B pancreatic cell proliferation	involved_in	ISO	Nkx6-1 (Rattus norvegicus)	9068941	PMID:24706823	UniProt	PMID:24706823 and REF_RGD_ID:10054075

Cellular Component

Only show annotations with direct experimental evidence (0 objects hidden)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
Nkx6-1	Squirrel	nucleus	located_in	IEA	UniProtKB-SubCell:SL-0191	150520179		UniProt	GO_REF:0000044
Nkx6-1	Squirrel	nucleus	located_in	IEA	PANTHER:PTN004692492	150520179		TreeGrafter	GO_REF:0000118
Nkx6-1	Squirrel	nucleus	located_in	IEA	UniProtKB-KW:KW-0539	150520179		UniProt	GO_REF:0000043
Nkx6-1	Squirrel	nucleus	located_in	IEA	UniProtKB:Q99MA9 and ensembl:ENSMUSP00000042716	150520179		Ensembl	GO_REF:0000107
Nkx6-1	Squirrel	nucleus	located_in	IEA	UniRule:UR000401037	150520179		UniProt	GO_REF:0000104

Molecular Function

Only show annotations with direct experimental evidence (0 objects hidden)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
Nkx6-1	Squirrel	chromatin binding		ISO	Nkx6-1 (Rattus norvegicus)	9068941		RGD	PMID:15883383 and REF_RGD_ID:2306242
Nkx6-1	Squirrel	DNA binding	enables	IEA	InterPro:IPR000047 more ...	150520179		InterPro	GO_REF:0000002
Nkx6-1	Squirrel	DNA binding	enables	IEA	UniProtKB-KW:KW-0238 and UniProtKB-KW:KW-0371	150520179		UniProt	GO_REF:0000043
Nkx6-1	Squirrel	DNA binding	enables	IEA	UniRule:UR000401037	150520179		UniProt	GO_REF:0000104
Nkx6-1	Squirrel	DNA-binding transcription factor activity		ISO	Nkx6-1 (Rattus norvegicus)	9068941		RGD	PMID:10567713 and REF_RGD_ID:68818
Nkx6-1	Squirrel	DNA-binding transcription factor activity, RNA polymerase II-specific	enables	IEA	InterPro:IPR017970	150520179		InterPro	GO_REF:0000002
Nkx6-1	Squirrel	DNA-binding transcription factor activity, RNA polymerase II-specific	enables	IEA	PANTHER:PTN004692492	150520179		TreeGrafter	GO_REF:0000118
Nkx6-1	Squirrel	DNA-binding transcription repressor activity, RNA polymerase II-specific	enables	ISO	Nkx6-1 (Rattus norvegicus)	9068941	PMID:15883383	NTNU_SB	PMID:15883383 and REF_RGD_ID:2306242
Nkx6-1	Squirrel	RNA polymerase II cis-regulatory region sequence-specific DNA binding	enables	IEA	PANTHER:PTN004692492	150520179		TreeGrafter	GO_REF:0000118
Nkx6-1	Squirrel	sequence-specific DNA binding		ISO	Nkx6-1 (Rattus norvegicus)	9068941		RGD	PMID:15883383 and REF_RGD_ID:2306242

PMID:22301074	PMID:30032202

Nkx6-1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024405285	4,155,070 - 4,162,340 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936738	317,907 - 324,235 (+)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936738	318,020 - 322,869 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

NKX6-1
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	4	84,491,985 - 84,499,292 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	4	84,491,985 - 84,499,292 (-)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	4	85,413,138 - 85,420,445 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	4	85,633,460 - 85,638,411 (-)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	4	85,771,614 - 85,776,566	NCBI
Celera	4	82,704,620 - 82,709,571 (-)	NCBI		Celera
Cytogenetic Map	4	q21.23	NCBI
HuRef	4	81,156,194 - 81,161,143 (-)	NCBI		HuRef
CHM1_1	4	85,391,105 - 85,396,056 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	4	87,821,981 - 87,829,288 (-)	NCBI		T2T-CHM13v2.0

Nkx6-1
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	5	101,807,050 - 101,812,577 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	5	101,806,005 - 101,812,862 (-)	Ensembl		GRCm39 Ensembl
GRCm38	5	101,659,184 - 101,664,711 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	5	101,658,139 - 101,664,996 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	5	102,088,203 - 102,093,730 (-)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	5	101,899,486 - 101,905,013 (-)	NCBI		MGSCv36	mm8
Celera	5	98,983,622 - 98,988,403 (-)	NCBI		Celera
Cytogenetic Map	5	E4- E5	NCBI
cM Map	5	48.84	NCBI

Nkx6-1
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	14	8,274,238 - 8,281,171 (+)	NCBI		GRCr8
mRatBN7.2	14	7,969,756 - 7,976,689 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	14	7,969,756 - 7,976,681 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	14	7,937,406 - 7,944,335 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	14	9,237,642 - 9,244,571 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	14	7,933,803 - 7,940,732 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	14	9,555,264 - 9,562,197 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	14	9,555,264 - 9,562,189 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	14	9,516,942 - 9,523,875 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	14	9,214,743 - 9,221,676 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	14	9,214,742 - 9,221,668 (+)	NCBI
Celera	14	8,087,941 - 8,094,874 (+)	NCBI		Celera
Cytogenetic Map	14	p22	NCBI

Nkx6-1
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0	NW_004955474	5,211,281 - 5,214,785 (+)	NCBI	ChiLan1.0	ChiLan1.0

NKX6-1
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	3	45,550,491 - 45,556,815 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	4	45,739,898 - 45,746,216 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	4	39,683,420 - 39,689,651 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	4	45,534,145 - 45,538,784 (+)	NCBI	panpan1.1	PanPan1.1	panPan2

NKX6-1
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	32	8,256,513 - 8,263,238 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	32	8,256,254 - 8,262,004 (-)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	32	33,622,505 - 33,627,982 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	32	8,275,814 - 8,281,289 (-)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	32	8,275,544 - 8,281,289 (-)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	32	8,357,520 - 8,362,989 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	32	8,219,935 - 8,225,407 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	32	31,736,036 - 31,741,514 (+)	NCBI		UU_Cfam_GSD_1.0

NKX6-1
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	8	134,138,097 - 134,144,254 (+)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	8	134,137,064 - 134,143,524 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	8	143,799,026 - 143,801,555 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

NKX6-1
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	7	32,846,436 - 32,851,526 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	7	32,846,528 - 32,851,447 (-)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666037	11,472,384 - 11,478,823 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Nkx6-1
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624900	1,618,563 - 1,623,793 (-)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624900	1,618,019 - 1,623,975 (-)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.


RefSeq Transcripts	XM_005339304	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	JAESOR010000344	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSSTOT00000012584 ⟹ ENSSTOP00000011277

Type:

CODING

Position:

Squirrel Assembly	Chr	Position (strand)	Source
SpeTri2.0 Ensembl	NW_004936738	317,907 - 324,235 (+)	Ensembl

RefSeq Acc Id:

XM_005339304 ⟹ XP_005339361

Type:

CODING

Position:

Squirrel Assembly	Chr	Position (strand)	Source
HiC_Itri_2	NW_024405285	4,155,070 - 4,162,340 (+)	NCBI
SpeTri2.0	NW_004936738	318,020 - 322,869 (+)	NCBI

Sequence:

show sequence

ATGTTAGCAGTGGGGGCGATGGAGGGCACCCGGCAGAGTGCATTCCTGCTCAGCAGTCCGCCCCTGGCCGCCCTGCACAGCATGGCCGAGATGAAGACCCCGCTGTACCCCGCCGCCTACCCCCCGTT
GCCCACTGGCCCCCCTTCCTCCTCGTCCTCGTCTTCCTCGTCCTCGTCGCCCTCCCCGCCTTTGGGCGCCCACAACCCCAGCGGCCTGAAGCCCCCAGCCGCAGGGGGGCTCTCGTCCCTGGGCAGTC
CCCCTCAGCAGCTCTCGGCCGCCACCCCACACGGCATCAACGACATCCTGAGCCGACCCTCCATGCCGGTGGCCTCTGGAGCCGCCCTGCCCTCAGCCTCTCCCTCTGGTTCCTCCTCCTCATCTTCC
TCGTCAGCTTCTGCTTCCTCCGCCTCTGCGGCGGCTGCCGCTGCTGCTGCGGCCGCGGCAGCTGCCTCATCCCCGGCTGGGCTGCTGGCCGGCCTGCCCCGCTTCAGCAGCCTGAGCCCGCCACCGCC
GCCTCCTGGGCTCTACTTCAGCCCTAGTGCAGCAGCCGTGGCCGCGGTGGGCCGGTACCCCAAACCACTGGCTGAGCTGCCCGGCCGGACGCCCATCTTCTGGCCAGGAGTGATGCAGAGCCCGCCCT
GGAGGGATGCACGCCTGGCCTGTACCCCTCATCAAGGATCCATTTTGTTGGACAAAGACGGGAAGAGAAAACACACGAGACCCACGTTCTCTGGCCAGCAGATCTTTGCTCTGGAGAAGACCTTCGAA
CAAACGAAATACTTGGCTGGGCCAGAGAGAGCTCGCTTGGCCTATTCGTTGGGGATGACGGAGAGTCAGGTCAAGGTCTGGTTCCAGAACCGCCGGACCAAGTGGAGGAAGAAGCACGCGGCCGAGAT
GGCGACAGCCAAGAAGAAGCAGGACTCGGAGACCGAGCGGCTCAAGGGGGCCTCGGAGAACGAGGAAGAAGACGACGACTACAACAAGCCTCTGGACCCCAACTCGGACGACGAGAAAATCACGCAGC
TGCTGAAGAAGCACAAATCCAGCGGCGGCGGCGGCGGCCTCCTGCTGCACGCGTCCGAGAACGAGGGCTCGTCCTGAGCGC

hide sequence


Protein RefSeqs	XP_005339361	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSSTOP00000011277.2
GenBank Protein	KAG3276325	(Get FASTA)	NCBI Sequence Viewer

RefSeq Acc Id:

XP_005339361 ⟸ XM_005339304

- UniProtKB:

I3MJF4 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MLAVGAMEGTRQSAFLLSSPPLAALHSMAEMKTPLYPAAYPPLPTGPPSSSSSSSSSSSPSPPLGAHNPSGLKPPAAGGLSSLGSPPQQLSAATPHGINDILSRPSMPVASGAALPSASPSGSSSSSS
SSASASSASAAAAAAAAAAAAASSPAGLLAGLPRFSSLSPPPPPPGLYFSPSAAAVAAVGRYPKPLAELPGRTPIFWPGVMQSPPWRDARLACTPHQGSILLDKDGKRKHTRPTFSGQQIFALEKTFE
QTKYLAGPERARLAYSLGMTESQVKVWFQNRRTKWRKKHAAEMATAKKKQDSETERLKGASENEEEDDDYNKPLDPNSDDEKITQLLKKHKSSGGGGGLLLHASENEGSS

hide sequence

Ensembl Acc Id:

ENSSTOP00000011277 ⟸ ENSSTOT00000012584

Protein Domains

Homeobox

Database	Acc Id	Source(s)
Ensembl Genes	ENSSTOG00000012588	Ensembl, UniProtKB/TrEMBL
Ensembl Transcript	ENSSTOT00000012584.3	UniProtKB/TrEMBL
Gene3D-CATH	Homeodomain-like	UniProtKB/TrEMBL
InterPro	Homeobox-like_sf	UniProtKB/TrEMBL
	Homeobox_CS	UniProtKB/TrEMBL
	Homeobox_dom	UniProtKB/TrEMBL
	Homeobox_metazoa	UniProtKB/TrEMBL
	Homeobox_NK-like	UniProtKB/TrEMBL
	HTH_motif	UniProtKB/TrEMBL
NCBI Gene	Nkx6-1	ENTREZGENE
PANTHER	HOMEOBOX PROTEIN NKX	UniProtKB/TrEMBL
	PTHR24340:SF31	UniProtKB/TrEMBL
Pfam	Homeodomain	UniProtKB/TrEMBL
PRINTS	HOMEOBOX	UniProtKB/TrEMBL
	HTHREPRESSR	UniProtKB/TrEMBL
PROSITE	HOMEOBOX_1	UniProtKB/TrEMBL
	HOMEOBOX_2	UniProtKB/TrEMBL
SMART	HOX	UniProtKB/TrEMBL
Superfamily-SCOP	SSF46689	UniProtKB/TrEMBL
UniProt	I3MJF4	ENTREZGENE, UniProtKB/TrEMBL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailable


InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailable


Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
		Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable

Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD

Send us a Message

Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD