Dcx (doublecortin) - Rat Genome Database

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Gene: Dcx (doublecortin) Ictidomys tridecemlineatus
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Symbol: Dcx
Name: doublecortin
RGD ID: 12596533
Description: ENCODES a protein that exhibits protein kinase binding (ortholog); INVOLVED IN axon extension (ortholog); brain development (ortholog); central nervous system projection neuron axonogenesis (ortholog); ASSOCIATED WITH Abnormal Cortical Gyration (ortholog); alcohol use disorder (ortholog); autistic disorder (ortholog); FOUND IN axon (ortholog); dendrite (ortholog); GABA-ergic synapse (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: neuronal migration protein doublecortin
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: SpeTri2.0 - Squirrel SpeTri2.0 Assembly
Position:
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2X83,645,350 - 83,761,221 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049364993,903,376 - 4,005,508 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049364993,905,262 - 4,004,457 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Dcx
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2X83,645,350 - 83,761,221 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049364993,903,376 - 4,005,508 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049364993,905,262 - 4,004,457 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
DCX
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38X111,293,779 - 111,412,192 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 EnsemblX111,293,779 - 111,412,429 (-)EnsemblGRCh38hg38GRCh38
GRCh37X110,537,007 - 110,655,420 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36X110,423,663 - 110,542,062 (-)NCBINCBI36Build 36hg18NCBI36
Build 34X110,343,151 - 110,461,551NCBI
CeleraX111,016,623 - 111,134,992 (-)NCBICelera
Cytogenetic MapXq23NCBI
HuRefX100,159,414 - 100,278,099 (-)NCBIHuRef
CHM1_1X110,448,522 - 110,566,950 (-)NCBICHM1_1
T2T-CHM13v2.0X109,741,985 - 109,860,408 (-)NCBIT2T-CHM13v2.0
Dcx
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39X142,638,838 - 142,716,392 (-)NCBIGRCm39GRCm39mm39
GRCm39 EnsemblX142,638,838 - 142,716,307 (-)EnsemblGRCm39 Ensembl
GRCm38X143,855,842 - 143,933,396 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 EnsemblX143,855,842 - 143,933,311 (-)EnsemblGRCm38mm10GRCm38
MGSCv37X140,290,385 - 140,367,762 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36X139,102,210 - 139,179,587 (-)NCBIMGSCv36mm8
CeleraX127,810,174 - 127,886,575 (-)NCBICelera
Cytogenetic MapXF2NCBI
cM MapX64.89NCBI
Dcx
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8X112,227,455 - 112,370,291 (-)NCBIGRCr8
mRatBN7.2X107,430,767 - 107,573,612 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 EnsemblX107,430,767 - 107,507,476 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_UtxX109,568,465 - 109,645,129 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0X113,068,174 - 113,144,836 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0X110,621,867 - 110,698,568 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0X115,098,675 - 115,175,515 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 EnsemblX115,098,675 - 115,175,299 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0X113,551,874 - 113,628,283 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4X34,596,262 - 34,672,383 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1X34,649,730 - 34,718,439NCBI
CeleraX106,829,783 - 106,906,206 (-)NCBICelera
Cytogenetic MapXq33-q34NCBI
Dcx
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554904,354,307 - 4,469,055 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554904,354,307 - 4,469,055 (+)NCBIChiLan1.0ChiLan1.0
DCX
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2X110,786,778 - 110,904,747 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1X110,790,383 - 110,908,353 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0X100,411,871 - 100,529,833 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1X110,878,060 - 110,988,303 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 EnsemblX110,875,032 - 110,988,582 (-)Ensemblpanpan1.1panPan2
DCX
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1X84,408,762 - 84,541,157 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 EnsemblX84,408,895 - 84,517,827 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_TashaX70,501,790 - 70,641,477 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0X86,062,412 - 86,202,409 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 EnsemblX86,062,955 - 86,179,258 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1X83,553,159 - 83,685,002 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0X85,222,965 - 85,362,879 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0X85,051,446 - 85,192,159 (-)NCBIUU_Cfam_GSD_1.0
DCX
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 EnsemblX91,323,764 - 91,644,567 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1X91,317,671 - 91,644,572 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2X105,739,468 - 106,059,734 (-)NCBISscrofa10.2Sscrofa10.2susScr3
DCX
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1X99,106,291 - 99,220,479 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 EnsemblX99,120,505 - 99,220,237 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366606524,340,271 - 24,459,762 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Dcx
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248034,168,556 - 4,299,979 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248034,168,556 - 4,304,642 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression

RNA-SEQ Expression


Sequence


Ensembl Acc Id: ENSSTOT00000020108   ⟹   ENSSTOP00000017762
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
SpeTri2.0 EnsemblNW_0049364993,903,376 - 4,005,508 (+)Ensembl
RefSeq Acc Id: XM_021725244   ⟹   XP_021580919
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2X83,645,350 - 83,754,573 (-)NCBI
SpeTri2.0NW_0049364993,905,262 - 4,004,457 (+)NCBI
Sequence:
RefSeq Acc Id: XM_040284340   ⟹   XP_040140274
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2X83,645,350 - 83,761,221 (-)NCBI
RefSeq Acc Id: XM_040284342   ⟹   XP_040140276
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2X83,645,350 - 83,761,221 (-)NCBI
RefSeq Acc Id: XM_040284351   ⟹   XP_040140285
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2X83,645,350 - 83,761,221 (-)NCBI
RefSeq Acc Id: XM_040284359   ⟹   XP_040140293
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2X83,645,350 - 83,754,574 (-)NCBI
RefSeq Acc Id: XM_040284369   ⟹   XP_040140303
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2X83,645,350 - 83,754,424 (-)NCBI
RefSeq Acc Id: XM_040284377   ⟹   XP_040140311
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2X83,645,350 - 83,761,221 (-)NCBI
RefSeq Acc Id: XM_040284389   ⟹   XP_040140323
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2X83,645,350 - 83,761,221 (-)NCBI
RefSeq Acc Id: XM_040284396   ⟹   XP_040140330
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2X83,645,350 - 83,761,221 (-)NCBI
RefSeq Acc Id: XM_040284400   ⟹   XP_040140334
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2X83,645,350 - 83,761,221 (-)NCBI
RefSeq Acc Id: XM_040284402   ⟹   XP_040140336
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2X83,645,350 - 83,761,221 (-)NCBI
RefSeq Acc Id: XM_040284406   ⟹   XP_040140340
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2X83,645,350 - 83,754,573 (-)NCBI
RefSeq Acc Id: XP_021580919   ⟸   XM_021725244
- Peptide Label: isoform X10
- Sequence:
RefSeq Acc Id: XP_040140330   ⟸   XM_040284396
- Peptide Label: isoform X7
RefSeq Acc Id: XP_040140323   ⟸   XM_040284389
- Peptide Label: isoform X6
RefSeq Acc Id: XP_040140311   ⟸   XM_040284377
- Peptide Label: isoform X5
RefSeq Acc Id: XP_040140336   ⟸   XM_040284402
- Peptide Label: isoform X9
RefSeq Acc Id: XP_040140285   ⟸   XM_040284351
- Peptide Label: isoform X3
RefSeq Acc Id: XP_040140274   ⟸   XM_040284340
- Peptide Label: isoform X1
RefSeq Acc Id: XP_040140276   ⟸   XM_040284342
- Peptide Label: isoform X2
RefSeq Acc Id: XP_040140334   ⟸   XM_040284400
- Peptide Label: isoform X8
RefSeq Acc Id: XP_040140293   ⟸   XM_040284359
- Peptide Label: isoform X4
RefSeq Acc Id: XP_040140340   ⟸   XM_040284406
- Peptide Label: isoform X11
- UniProtKB: I3N066 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_040140303   ⟸   XM_040284369
- Peptide Label: isoform X4
Ensembl Acc Id: ENSSTOP00000017762   ⟸   ENSSTOT00000020108
Protein Domains
Doublecortin


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSTOG00000023293 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSSTOT00000020108.2 UniProtKB/TrEMBL
Gene3D-CATH 3.10.20.230 UniProtKB/TrEMBL
InterPro DCX/DCDC2-like UniProtKB/TrEMBL
  Doublecortin_chordata UniProtKB/TrEMBL
  Doublecortin_dom UniProtKB/TrEMBL
  Doublecortin_dom_sf UniProtKB/TrEMBL
NCBI Gene Dcx ENTREZGENE
PANTHER DOUBLECORTIN DOMAIN CONTAINING 2 UniProtKB/TrEMBL
  PROTEIN RPI-1 UniProtKB/TrEMBL
Pfam DCX UniProtKB/TrEMBL
PIRSF Doublin UniProtKB/TrEMBL
PROSITE PS50309 UniProtKB/TrEMBL
SMART DCX UniProtKB/TrEMBL
Superfamily-SCOP SSF89837 UniProtKB/TrEMBL
UniProt I3N066 ENTREZGENE, UniProtKB/TrEMBL