Dcx (doublecortin) - Rat Genome Database

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Gene: Dcx (doublecortin) Mus musculus
Analyze
Symbol: Dcx
Name: doublecortin
RGD ID: 731627
MGI Page MGI
Description: Predicted to enable microtubule binding activity and protein kinase binding activity. Acts upstream of or within hippocampus development and neurogenesis. Located in cytoplasm and neuron projection. Is expressed in several structures, including gut; limb; nervous system; retina; and urinary system. Used to study lissencephaly. Human ortholog(s) of this gene implicated in X-linked lissencephaly 1 and subcortical band heterotopia. Orthologous to human DCX (doublecortin).
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: Dbct; doublecortex; doublin; lis-X; lissencephalin-X; lissencephaly, X-linked (doublecortin); neuronal migration protein doublecortin
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39X142,638,838 - 142,716,392 (-)NCBIGRCm39mm39
GRCm39 EnsemblX142,638,838 - 142,716,307 (-)Ensembl
GRCm38X143,855,842 - 143,933,396 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 EnsemblX143,855,842 - 143,933,311 (-)EnsemblGRCm38mm10GRCm38
MGSCv37X140,290,385 - 140,367,762 (-)NCBIGRCm37mm9NCBIm37
MGSCv36X139,102,210 - 139,179,587 (-)NCBImm8
CeleraX127,810,174 - 127,886,575 (-)NCBICelera
Cytogenetic MapXF2NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype
abnormal anterior commissure morphology  (IAGP)
abnormal avoidance learning behavior  (IAGP)
abnormal behavior  (IAGP)
abnormal brain commissure morphology  (IAGP)
abnormal brain internal capsule morphology  (IAGP)
abnormal brain interneuron morphology  (IAGP)
abnormal brain morphology  (IAGP)
abnormal brainstem morphology  (IAGP)
abnormal cerebellar foliation  (IAGP)
abnormal cerebral cortex morphology  (IAGP)
abnormal corpus callosum morphology  (IAGP)
abnormal dentate gyrus morphology  (IAGP)
abnormal entorhinal cortex morphology  (IAGP)
abnormal hippocampal commissure morphology  (IAGP)
abnormal hippocampal mossy fiber morphology  (IAGP)
abnormal hippocampus CA1 region morphology  (IAGP)
abnormal hippocampus CA3 region morphology  (IAGP)
abnormal hippocampus granule cell layer  (IAGP)
abnormal hippocampus layer morphology  (IAGP)
abnormal hippocampus morphology  (IAGP)
abnormal hippocampus pyramidal cell layer  (IAGP)
abnormal hippocampus pyramidal cell morphology  (IAGP)
abnormal hippocampus region morphology  (IAGP)
abnormal inhibitory postsynaptic currents  (IAGP)
abnormal neuron morphology  (IAGP)
abnormal rostral migratory stream morphology  (IAGP)
abnormal spatial learning  (IAGP)
abnormal stratification in cerebral cortex  (IAGP)
abnormal striatum morphology  (IAGP)
abnormal temporal lobe morphology  (IAGP)
abnormal thalamus morphology  (IAGP)
absent anterior commissure  (IAGP)
absent brain internal capsule  (IAGP)
absent corpus callosum  (IAGP)
absent hippocampal commissure  (IAGP)
convulsive seizures  (IAGP)
decreased anterior commissure size  (IAGP)
decreased body size  (IAGP)
decreased corpus callosum size  (IAGP)
decreased grip strength  (IAGP)
enlarged lateral ventricles  (IAGP)
increased circulating chloride level  (IEA)
increased circulating insulin level  (IEA)
increased circulating sodium level  (IEA)
loss of hippocampal neurons  (IAGP)
postnatal lethality  (IAGP)
postnatal lethality, complete penetrance  (IAGP)
postnatal lethality, incomplete penetrance  (IAGP)
premature death  (IAGP)
reduced female fertility  (IAGP)
reduced male fertility  (IAGP)
small cerebellum  (IAGP)
thin cerebral cortex  (IAGP)
tonic-clonic seizures  (IAGP)
References

References - curated
1. Aigner L, etal., Neuropediatrics. 2000 Aug;31(4):195-8.
2. Chae TH, etal., Nat Genet 2004 Mar;36(3):264-70. Epub 2004 Feb 1.
3. Corbo JC, etal., J Neurosci 2002 Sep 1;22(17):7548-57.
4. D'Alessio L, etal., Seizure. 2010 Nov;19(9):567-72. doi: 10.1016/j.seizure.2010.09.004.
5. des Portes V, etal., Hum Mol Genet. 1998 Jul;7(7):1063-70.
6. Guerrini R, etal., Ann Neurol. 2003 Jul;54(1):30-7.
7. Haverfield EV, etal., Eur J Hum Genet. 2009 Jul;17(7):911-8. doi: 10.1038/ejhg.2008.213. Epub 2008 Dec 3.
8. Kato M, etal., Hum Genet. 1999 Apr;104(4):341-4.
9. Kawai J, etal., Nature. 2001 Feb 8;409(6821):685-90.
10. Lapray D, etal., Cereb Cortex. 2010 Nov;20(11):2694-701. doi: 10.1093/cercor/bhq014. Epub 2010 Feb 17.
11. Manent JB, etal., Nat Med. 2009 Jan;15(1):84-90. doi: 10.1038/nm.1897. Epub 2008 Dec 21.
12. MGD data from the GO Consortium
13. Nosten-Bertrand M, etal., PLoS One. 2008 Jun 25;3(6):e2473. doi: 10.1371/journal.pone.0002473.
14. Okazaki Y, etal., Nature. 2002 Dec 5;420(6915):563-73.
15. OMIM Disease Annotation Pipeline
16. RGD automated import pipeline
17. RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
18. RGD automated import pipeline for gene-chemical interactions
19. Santra M, etal., Cancer Res. 2006 Dec 15;66(24):11726-35.
20. Santra M, etal., Cancer Sci. 2011 Jul;102(7):1350-7. doi: 10.1111/j.1349-7006.2011.01952.x. Epub 2011 May 10.
21. Santra M, etal., J Neurosci Res. 2010 Feb 1;88(2):304-14. doi: 10.1002/jnr.22207.
22. Tsai MH, etal., Eur J Paediatr Neurol. 2016 Sep;20(5):788-94. doi: 10.1016/j.ejpn.2016.05.010. Epub 2016 May 30.
23. Wang Y, etal., Arch Med Res. 2012 May;43(4):255-64. doi: 10.1016/j.arcmed.2012.05.002. Epub 2012 May 15.
24. Xu X, etal., Nan Fang Yi Ke Da Xue Xue Bao. 2013 Oct;33(10):1437-41.
25. Yi SS, etal., Neurochem Res. 2009 Jun;34(6):1039-46. doi: 10.1007/s11064-008-9870-y. Epub 2008 Nov 4.
Additional References at PubMed
PMID:2137249   PMID:9489700   PMID:9668176   PMID:9747029   PMID:9837748   PMID:10349636   PMID:10399932   PMID:10399933   PMID:10533048   PMID:11042159   PMID:11076861   PMID:11124993  
PMID:11239428   PMID:11287186   PMID:11544199   PMID:11591131   PMID:12040030   PMID:12130536   PMID:12477932   PMID:12595570   PMID:14550532   PMID:14741103   PMID:14765123   PMID:15099191  
PMID:15328020   PMID:15345747   PMID:15473967   PMID:15607950   PMID:15632197   PMID:15654838   PMID:15733660   PMID:16038893   PMID:16099729   PMID:16116448   PMID:16141072   PMID:16141073  
PMID:16387638   PMID:16387639   PMID:16432194   PMID:16436614   PMID:16476661   PMID:16518823   PMID:16530423   PMID:16571605   PMID:16602821   PMID:16632597   PMID:16699506   PMID:16766710  
PMID:16777961   PMID:16869982   PMID:16892058   PMID:16920270   PMID:16931042   PMID:16944949   PMID:16962712   PMID:17105671   PMID:17108173   PMID:17111359   PMID:17172441   PMID:17313568  
PMID:17409252   PMID:17409257   PMID:17462911   PMID:17482550   PMID:17507397   PMID:17533120   PMID:17589506   PMID:17591923   PMID:17671991   PMID:17875933   PMID:17878174   PMID:17888889  
PMID:17897623   PMID:17901127   PMID:18031938   PMID:18075262   PMID:18075264   PMID:18094249   PMID:18199763   PMID:18205207   PMID:18231966   PMID:18287559   PMID:18366138   PMID:18371392  
PMID:18462697   PMID:18469343   PMID:18477394   PMID:18513381   PMID:18550749   PMID:18562329   PMID:18579678   PMID:18599437   PMID:18616932   PMID:18637555   PMID:18649926   PMID:18651664  
PMID:18655203   PMID:18690213   PMID:18725516   PMID:18728187   PMID:18755297   PMID:18761331   PMID:18794345   PMID:18803236   PMID:18854839   PMID:18946489   PMID:19036994   PMID:19046368  
PMID:19243017   PMID:19287386   PMID:19303846   PMID:19342486   PMID:19490090   PMID:19538749   PMID:19553437   PMID:19563800   PMID:19573529   PMID:19587446   PMID:19710359   PMID:19712103  
PMID:19778507   PMID:19799774   PMID:19805316   PMID:19896444   PMID:19948250   PMID:20093372   PMID:20181597   PMID:20203209   PMID:20236041   PMID:20340168   PMID:20364144   PMID:20385829  
PMID:20399730   PMID:20436479   PMID:20460369   PMID:20473291   PMID:20509865   PMID:20529123   PMID:20529129   PMID:20549747   PMID:20620871   PMID:20629178   PMID:20715151   PMID:20737593  
PMID:20808958   PMID:20824214   PMID:20878181   PMID:20935640   PMID:20956558   PMID:21031554   PMID:21114965   PMID:21162077   PMID:21172336   PMID:21228099   PMID:21267068   PMID:21360195  
PMID:21423666   PMID:21436036   PMID:21451048   PMID:21466690   PMID:21471969   PMID:21561989   PMID:21677750   PMID:21689730   PMID:21737879   PMID:21776083   PMID:21804544   PMID:21824737  
PMID:21873635   PMID:21938487   PMID:22022443   PMID:22028625   PMID:22056141   PMID:22071110   PMID:22090513   PMID:22143493   PMID:22159417   PMID:22173850   PMID:22241837   PMID:22246438  
PMID:22250815   PMID:22334647   PMID:22367209   PMID:22405202   PMID:22492306   PMID:22522171   PMID:22573669   PMID:22586092   PMID:22588081   PMID:22605579   PMID:22645310   PMID:22705452  
PMID:22726441   PMID:22766235   PMID:22789544   PMID:22802532   PMID:22837015   PMID:22857951   PMID:22889265   PMID:22898830   PMID:22956844   PMID:22956851   PMID:22957010   PMID:23042739  
PMID:23064108   PMID:23100423   PMID:23196656   PMID:23293287   PMID:23303949   PMID:23416450   PMID:23447615   PMID:23472759   PMID:23499385   PMID:23518711   PMID:23575857   PMID:23622239  
PMID:23643936   PMID:23644466   PMID:23665444   PMID:23667508   PMID:23673330   PMID:23690918   PMID:23744272   PMID:23765158   PMID:23776487   PMID:23828756   PMID:23861879   PMID:23904595  
PMID:23918955   PMID:23926259   PMID:23948251   PMID:24005285   PMID:24023755   PMID:24073232   PMID:24096375   PMID:24154525   PMID:24192035   PMID:24209760   PMID:24288185   PMID:24355921  
PMID:24367100   PMID:24483844   PMID:24487590   PMID:24496615   PMID:24535747   PMID:24550175   PMID:24695713   PMID:24726665   PMID:24874545   PMID:24875059   PMID:24886590   PMID:24945770  
PMID:24952961   PMID:25007825   PMID:25044744   PMID:25073924   PMID:25182747   PMID:25183872   PMID:25209608   PMID:25210733   PMID:25245017   PMID:25297105   PMID:25331604   PMID:25452572  
PMID:25480916   PMID:25521379   PMID:25527292   PMID:25533347   PMID:25556659   PMID:25556700   PMID:25575549   PMID:25757017   PMID:25972180   PMID:25999820   PMID:26067405   PMID:26094033  
PMID:26220976   PMID:26369386   PMID:26387477   PMID:26457609   PMID:26494286   PMID:26579598   PMID:26621269   PMID:26701169   PMID:26745185   PMID:26793044   PMID:26795843   PMID:26839365  
PMID:26902115   PMID:27147649   PMID:27166167   PMID:27222923   PMID:27251626   PMID:27320921   PMID:27449610   PMID:27452274   PMID:27469598   PMID:27648578   PMID:27664421   PMID:27701470  
PMID:27798843   PMID:27848932   PMID:28007902   PMID:28158408   PMID:28173130   PMID:28231465   PMID:28337978   PMID:28455369   PMID:28494873   PMID:28595361   PMID:28671696   PMID:28674667  
PMID:28705869   PMID:28715454   PMID:28739678   PMID:28768199   PMID:28794184   PMID:28808228   PMID:28837861   PMID:28981617   PMID:29021239   PMID:29082311   PMID:29088697   PMID:29255003  
PMID:29311744   PMID:29386106   PMID:29420689   PMID:29507213   PMID:29507409   PMID:29513653   PMID:29588831   PMID:29716946   PMID:29748916   PMID:29855337   PMID:29867343   PMID:29967281  
PMID:29973868   PMID:30008200   PMID:30250269   PMID:30333037   PMID:30385877   PMID:30447281   PMID:30472241   PMID:30626697   PMID:30692224   PMID:30796806   PMID:30819894   PMID:30853885  
PMID:30858607   PMID:30914320   PMID:31065682   PMID:31079925   PMID:31097699   PMID:31442405   PMID:31505254   PMID:31577226   PMID:31655624   PMID:31699896   PMID:31758234   PMID:31761722  
PMID:31801076   PMID:31806049   PMID:31914386   PMID:31935927   PMID:31969356   PMID:32000863   PMID:32049024   PMID:32098764   PMID:32122989   PMID:32142677   PMID:32161758   PMID:32234482  
PMID:32253238   PMID:32294450   PMID:32321712   PMID:32325033   PMID:32386572   PMID:32438638   PMID:32591430   PMID:33053356   PMID:33139841   PMID:33154347   PMID:33159114   PMID:33212822  
PMID:33277484   PMID:33405953   PMID:33602870   PMID:33723434   PMID:33790322   PMID:33938018   PMID:33976153   PMID:34010654   PMID:34381067  


Genomics

Comparative Map Data
Dcx
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39X142,638,838 - 142,716,392 (-)NCBIGRCm39mm39
GRCm39 EnsemblX142,638,838 - 142,716,307 (-)Ensembl
GRCm38X143,855,842 - 143,933,396 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 EnsemblX143,855,842 - 143,933,311 (-)EnsemblGRCm38mm10GRCm38
MGSCv37X140,290,385 - 140,367,762 (-)NCBIGRCm37mm9NCBIm37
MGSCv36X139,102,210 - 139,179,587 (-)NCBImm8
CeleraX127,810,174 - 127,886,575 (-)NCBICelera
Cytogenetic MapXF2NCBI
DCX
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 EnsemblX111,293,779 - 111,412,429 (-)EnsemblGRCh38hg38GRCh38
GRCh38X111,293,779 - 111,412,205 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh37X110,537,007 - 110,655,420 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36X110,423,663 - 110,542,062 (-)NCBINCBI36hg18NCBI36
Build 34X110,343,151 - 110,461,551NCBI
CeleraX111,016,623 - 111,134,992 (-)NCBI
Cytogenetic MapXq23NCBI
HuRefX100,159,414 - 100,278,099 (-)NCBIHuRef
CHM1_1X110,448,522 - 110,566,950 (-)NCBICHM1_1
Dcx
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2X107,430,767 - 107,573,612 (-)NCBImRatBN7.2
mRatBN7.2 EnsemblX107,430,767 - 107,507,476 (-)Ensembl
Rnor_6.0X115,098,675 - 115,175,515 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 EnsemblX115,098,675 - 115,175,299 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0X113,551,874 - 113,628,283 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4X34,596,262 - 34,672,383 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1X34,649,730 - 34,718,439NCBI
CeleraX106,829,783 - 106,906,206 (-)NCBICelera
Cytogenetic MapXq33-q34NCBI
Dcx
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554904,354,307 - 4,469,055 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554904,354,307 - 4,469,055 (+)NCBIChiLan1.0ChiLan1.0
DCX
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.1X110,878,060 - 110,988,303 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 EnsemblX110,875,032 - 110,988,582 (-)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v0X100,411,871 - 100,529,833 (-)NCBIMhudiblu_PPA_v0panPan3
DCX
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1X84,408,762 - 84,541,157 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 EnsemblX84,408,895 - 84,517,827 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_TashaX70,501,790 - 70,641,477 (-)NCBI
ROS_Cfam_1.0X86,062,412 - 86,202,409 (-)NCBI
UMICH_Zoey_3.1X83,553,159 - 83,685,002 (-)NCBI
UNSW_CanFamBas_1.0X85,222,965 - 85,362,879 (-)NCBI
UU_Cfam_GSD_1.0X85,051,446 - 85,192,159 (-)NCBI
Dcx
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2X83,645,350 - 83,761,221 (-)NCBI
SpeTri2.0NW_0049364993,905,262 - 4,004,457 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
DCX
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 EnsemblX91,323,768 - 91,644,567 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1X91,317,671 - 91,644,572 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2X105,739,468 - 106,059,734 (-)NCBISscrofa10.2Sscrofa10.2susScr3
DCX
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1X99,106,291 - 99,220,479 (-)NCBIChlSab1.1chlSab2
ChlSab1.1 EnsemblX99,120,505 - 99,220,237 (-)EnsemblChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366606524,340,271 - 24,459,762 (-)NCBIVero_WHO_p1.0
Dcx
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046248034,168,556 - 4,304,642 (+)NCBIHetGla_female_1.0hetGla2

Position Markers
DXMit216  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38X143,902,153 - 143,902,273UniSTSGRCm38
MGSCv37X140,336,696 - 140,336,816UniSTSGRCm37
CeleraX127,855,975 - 127,856,116UniSTS
Cytogenetic MapXF2UniSTS
cM MapX63.0UniSTS
Whitehead GeneticX50.3UniSTS
Whitehead_YACX UniSTS
RH124178  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38X143,862,445 - 143,863,499UniSTSGRCm38
MGSCv37X140,296,988 - 140,298,042UniSTSGRCm37
CeleraX127,816,777 - 127,817,831UniSTS
Cytogenetic MapXF2UniSTS
cM MapX UniSTS
Dcx  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38X143,856,689 - 143,857,342UniSTSGRCm38
MGSCv37X140,291,232 - 140,291,885UniSTSGRCm37
CeleraX127,811,021 - 127,811,674UniSTS
Cytogenetic MapXF2UniSTS


QTLs in Region (GRCm38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1357433Dbts2_mdiabetes 2 (mouse)Not determinedX7360056151324042Mouse
13824980Ferq1_mgenetic fertility QTL 1 (mouse)X55000000150000000Mouse
13208552Wght12_mweight 12 (mouse)X95000000151000000Mouse
13208556Lgth14_mbody length 14 (mouse)X95000000151000000Mouse
1357823Spha3_msperm head anomaly 3 (mouse)Not determinedX103012242163975945Mouse
1301209Cia19_mcollagen induced arthritis 19 (mouse)Not determinedX122083468161430042Mouse
25314309Syncl5_msynaptonemal complex length 5 (mouse)X123000000153800000Mouse
10412164Cmv2_mcytomegalovirus resistance 2 (mouse)Not determinedX126902153160902273Mouse
13824981Svwq2_mseminal vesicle weight QTL 2 (mouse)X130000000155000000Mouse
1558900Bw3_mbody weight QTL 3 (mouse)Not determinedX134639291166515599Mouse
1301276Tswt_mtestis weight (mouse)Not determinedX139475662152006342Mouse

miRNA Target Status

Confirmed Target Of
miRNA GeneMature miRNAMethod NameResult TypeData TypeSupport TypePMID
Mir134mmu-miR-134-5pMirtarbaseexternal_infoLuciferase reporter assay//qRT-PCR//Western blotFunctional MTI21228099

Predicted Target Of
Summary Value
Count of predictions:5139
Count of miRNA genes:892
Interacting mature miRNAs:1274
Transcripts:ENSMUST00000033642, ENSMUST00000087313, ENSMUST00000112851, ENSMUST00000112856, ENSMUST00000125768, ENSMUST00000139920
Prediction methods:Miranda, Pita, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001110222 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001110223 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001110224 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_010025 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006528698 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_030251212 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_030251213 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_030251214 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AB011678 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF045547 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK011597 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK014264 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK048410 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK049050 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK141942 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK164119 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK164139 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AY560329 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AY590498 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC056391 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC057010 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC062974 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BX530055 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CA315795 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CB525395 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CD350374 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CD802698 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH466610 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CJ102759 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSMUST00000033642   ⟹   ENSMUSP00000033642
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 EnsemblX142,638,838 - 142,716,307 (-)Ensembl
GRCm38.p6 EnsemblX143,855,842 - 143,933,311 (-)Ensembl
RefSeq Acc Id: ENSMUST00000087313   ⟹   ENSMUSP00000084570
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 EnsemblX142,644,778 - 142,716,120 (-)Ensembl
GRCm38.p6 EnsemblX143,861,782 - 143,933,124 (-)Ensembl
RefSeq Acc Id: ENSMUST00000112851   ⟹   ENSMUSP00000108472
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 EnsemblX142,643,707 - 142,716,200 (-)Ensembl
GRCm38.p6 EnsemblX143,860,711 - 143,933,204 (-)Ensembl
RefSeq Acc Id: ENSMUST00000112856   ⟹   ENSMUSP00000108477
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 EnsemblX142,646,469 - 142,716,215 (-)Ensembl
GRCm38.p6 EnsemblX143,863,473 - 143,933,219 (-)Ensembl
RefSeq Acc Id: ENSMUST00000125768
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 EnsemblX142,656,748 - 142,716,115 (-)Ensembl
GRCm38.p6 EnsemblX143,873,752 - 143,933,119 (-)Ensembl
RefSeq Acc Id: ENSMUST00000139920
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 EnsemblX142,652,206 - 142,716,046 (-)Ensembl
GRCm38.p6 EnsemblX143,869,210 - 143,933,050 (-)Ensembl
RefSeq Acc Id: NM_001110222   ⟹   NP_001103692
RefSeq Status: REVIEWED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39X142,638,838 - 142,716,120 (-)NCBI
GRCm38X143,855,842 - 143,933,124 (-)NCBI
MGSCv37X140,290,385 - 140,367,762 (-)RGD
CeleraX127,810,174 - 127,886,575 (-)RGD
cM MapX ENTREZGENE
Sequence:
RefSeq Acc Id: NM_001110223   ⟹   NP_001103693
RefSeq Status: REVIEWED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39X142,638,838 - 142,716,215 (-)NCBI
GRCm38X143,855,842 - 143,933,219 (-)NCBI
MGSCv37X140,290,385 - 140,367,762 (-)RGD
CeleraX127,810,174 - 127,886,575 (-)RGD
cM MapX ENTREZGENE
Sequence:
RefSeq Acc Id: NM_001110224   ⟹   NP_001103694
RefSeq Status: REVIEWED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39X142,638,838 - 142,716,215 (-)NCBI
GRCm38X143,855,842 - 143,933,219 (-)NCBI
MGSCv37X140,290,385 - 140,367,762 (-)RGD
CeleraX127,810,174 - 127,886,575 (-)RGD
cM MapX ENTREZGENE
Sequence:
RefSeq Acc Id: NM_010025   ⟹   NP_034155
RefSeq Status: REVIEWED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39X142,638,838 - 142,716,215 (-)NCBI
GRCm38X143,855,842 - 143,933,219 (-)NCBI
MGSCv37X140,290,385 - 140,367,762 (-)RGD
CeleraX127,810,174 - 127,886,575 (-)RGD
cM MapX ENTREZGENE
Sequence:
RefSeq Acc Id: XM_006528698   ⟹   XP_006528761
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39X142,638,838 - 142,716,392 (-)NCBI
GRCm38X143,855,842 - 143,933,396 (-)NCBI
Sequence:
RefSeq Acc Id: XM_030251212   ⟹   XP_030107072
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39X142,638,838 - 142,716,279 (-)NCBI
GRCm38X143,855,842 - 143,933,271 (-)NCBI
Sequence:
RefSeq Acc Id: XM_030251213   ⟹   XP_030107073
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39X142,638,838 - 142,716,286 (-)NCBI
GRCm38X143,855,842 - 143,933,277 (-)NCBI
Sequence:
RefSeq Acc Id: XM_030251214   ⟹   XP_030107074
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39X142,638,838 - 142,716,286 (-)NCBI
GRCm38X143,855,842 - 143,933,277 (-)NCBI
Sequence:
Reference Sequences
RefSeq Acc Id: NP_034155   ⟸   NM_010025
- Peptide Label: isoform c
- UniProtKB: O88809 (UniProtKB/Swiss-Prot),   Q6PGI2 (UniProtKB/TrEMBL),   Q9CXL6 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001103693   ⟸   NM_001110223
- Peptide Label: isoform a
- UniProtKB: O88809 (UniProtKB/Swiss-Prot),   Q6PGI2 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001103694   ⟸   NM_001110224
- Peptide Label: isoform b
- UniProtKB: O88809 (UniProtKB/Swiss-Prot),   Q6PGI2 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001103692   ⟸   NM_001110222
- Peptide Label: isoform a
- UniProtKB: O88809 (UniProtKB/Swiss-Prot),   Q6PGI2 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006528761   ⟸   XM_006528698
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: XP_030107074   ⟸   XM_030251214
- Peptide Label: isoform X3
RefSeq Acc Id: XP_030107073   ⟸   XM_030251213
- Peptide Label: isoform X2
RefSeq Acc Id: XP_030107072   ⟸   XM_030251212
- Peptide Label: isoform X1
RefSeq Acc Id: ENSMUSP00000108477   ⟸   ENSMUST00000112856
RefSeq Acc Id: ENSMUSP00000084570   ⟸   ENSMUST00000087313
RefSeq Acc Id: ENSMUSP00000108472   ⟸   ENSMUST00000112851
RefSeq Acc Id: ENSMUSP00000033642   ⟸   ENSMUST00000033642
Protein Domains
Doublecortin

Promoters
RGD ID:13681568
Promoter ID:EPDNEW_M24933
Type:initiation region
Name:Dcx_1
Description:Mus musculus doublecortin , transcript variant 1, mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38X143,933,103 - 143,933,163EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:1277171 AgrOrtholog
Ensembl Genes ENSMUSG00000031285 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Protein ENSMUSP00000033642 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSMUSP00000084570 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSMUSP00000108472 ENTREZGENE, UniProtKB/TrEMBL
  ENSMUSP00000108477 ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000033642 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSMUST00000087313 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSMUST00000112851 ENTREZGENE, UniProtKB/TrEMBL
  ENSMUST00000112856 ENTREZGENE, UniProtKB/TrEMBL
Gene3D-CATH 3.10.20.230 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro Doublecortin_chordata UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Doublecortin_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Doublecortin_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  RP1/RP1L1/DCX UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:13193 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
MGD MGI:1277171 ENTREZGENE
NCBI Gene 13193 ENTREZGENE
PANTHER PTHR23005 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam DCX UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Dcx PhenoGen
PIRSF Doublin UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE PS50309 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART DCX UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF89837 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt DCX_MOUSE UniProtKB/Swiss-Prot, ENTREZGENE
  Q3V349_MOUSE UniProtKB/TrEMBL
  Q6PGI2 ENTREZGENE, UniProtKB/TrEMBL
  Q8C852_MOUSE UniProtKB/TrEMBL
  Q9CXL6 ENTREZGENE, UniProtKB/TrEMBL
UniProt Secondary Q6E5A4 UniProtKB/Swiss-Prot