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Gene: Dcx (doublecortin) Mus musculus
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Symbol: Dcx
Name: doublecortin
Description: Predicted to have microtubule binding activity and protein kinase binding activity. Involved in hippocampus development and neurogenesis. Localizes to cytoplasm and neuron projection. Predicted to colocalize with microtubule. Is expressed in several structures, including gut; limb segment; nervous system; retina; and urinary system. Used to study lissencephaly. Human ortholog(s) of this gene implicated in lissencephaly and subcortical band heterotopia. Orthologous to human DCX (doublecortin).
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: Dbct; doublecortex; doublin; lis-X; lissencephalin-X; lissencephaly, X-linked (doublecortin); neuronal migration protein doublecortin
Orthologs:
Homo sapiens (human) : DCX (doublecortin)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Dcx (doublecortin)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Dcx (doublecortin)
Pan paniscus (bonobo/pygmy chimpanzee) : DCX (doublecortin)
Canis lupus familiaris (dog) : DCX (doublecortin)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Dcx (doublecortin)
Sus scrofa (pig) : DCX (doublecortin)
Chlorocebus sabaeus (African green monkey) : DCX (doublecortin)
Heterocephalus glaber (naked mole-rat) : Dcx (doublecortin)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm38.p6 EnsemblX143,855,842 - 143,933,311 (-)EnsemblGRCm38mm10GRCm38
GRCm38X143,855,842 - 143,933,396 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv37X140,290,385 - 140,367,762 (-)NCBIGRCm37mm9NCBIm37
MGSCv36X139,102,210 - 139,179,587 (-)NCBImm8
CeleraX127,810,174 - 127,886,575 (-)NCBICelera
Cytogenetic MapXF2NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Dcx
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 731627
Created: 2004-01-12
Species: Mus musculus
Last Modified: 2020-06-30
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.