Ppm1f (protein phosphatase, Mg2+/Mn2+ dependent 1F) - Rat Genome Database

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Gene: Ppm1f (protein phosphatase, Mg2+/Mn2+ dependent 1F) Ictidomys tridecemlineatus
Analyze
Symbol: Ppm1f
Name: protein phosphatase, Mg2+/Mn2+ dependent 1F
RGD ID: 12573340
Description: ENCODES a protein that exhibits phosphoprotein phosphatase activity (ortholog); protein serine/threonine phosphatase activity (ortholog); INVOLVED IN negative regulation of peptidyl-serine phosphorylation (ortholog); negative regulation of protein kinase activity (ortholog); negative regulation of protein kinase activity by regulation of protein phosphorylation (ortholog); PARTICIPATES IN adenosine monophosphate-activated protein kinase (AMPK) signaling pathway; calcium/calmodulin dependent kinase 2 signaling pathway; ASSOCIATED WITH chromosome 22q11.2 deletion syndrome, distal (ortholog); DiGeorge syndrome (ortholog); FOUND IN perinuclear region of cytoplasm (ortholog)
Type: protein-coding
RefSeq Status: MODEL
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: SpeTri2.0 - Squirrel SpeTri2.0 Assembly
Position:
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405118140,937,979 - 140,967,888 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049366191,786,178 - 1,816,109 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049366191,786,223 - 1,816,083 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Ppm1f
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405118140,937,979 - 140,967,888 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049366191,786,178 - 1,816,109 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049366191,786,223 - 1,816,083 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
PPM1F
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382221,919,425 - 21,952,848 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2221,919,425 - 21,952,848 (-)EnsemblGRCh38hg38GRCh38
GRCh372222,273,798 - 22,307,220 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 362220,603,793 - 20,637,217 (-)NCBINCBI36Build 36hg18NCBI36
Build 342220,598,346 - 20,631,771NCBI
Celera226,091,333 - 6,124,791 (-)NCBICelera
Cytogenetic Map22q11.22NCBI
HuRef225,230,870 - 5,264,327 (-)NCBIHuRef
CHM1_12222,273,889 - 22,307,348 (-)NCBICHM1_1
T2T-CHM13v2.02222,332,962 - 22,366,379 (-)NCBIT2T-CHM13v2.0
Ppm1f
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391616,714,314 - 16,745,239 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1616,714,333 - 16,745,228 (+)EnsemblGRCm39 Ensembl
GRCm381616,896,469 - 16,927,375 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1616,896,469 - 16,927,364 (+)EnsemblGRCm38mm10GRCm38
MGSCv371616,903,414 - 16,927,455 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361616,816,884 - 16,840,925 (+)NCBIMGSCv36mm8
Celera1617,475,388 - 17,499,499 (+)NCBICelera
Cytogenetic Map16A3NCBI
cM Map1610.48NCBI
Ppm1f
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81197,568,627 - 97,598,613 (-)NCBIGRCr8
mRatBN7.21184,064,422 - 84,094,410 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1184,064,420 - 84,094,340 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1192,790,922 - 92,818,479 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01185,452,053 - 85,479,612 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01184,505,643 - 84,533,204 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01188,313,709 - 88,343,726 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1188,313,709 - 88,343,627 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01191,368,795 - 91,398,731 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41186,086,968 - 86,114,278 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11186,127,564 - 86,154,875 (-)NCBI
Celera1182,821,775 - 82,848,989 (-)NCBICelera
Cytogenetic Map11q23NCBI
Ppm1f
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495544217,227,723 - 17,252,383 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495544217,233,258 - 17,256,009 (+)NCBIChiLan1.0ChiLan1.0
PPM1F
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22331,461,495 - 31,494,626 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12234,010,360 - 34,043,505 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0224,039,032 - 4,072,165 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12220,520,022 - 20,553,128 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2220,520,022 - 20,553,128 (-)Ensemblpanpan1.1panPan2
PPM1F
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12631,162,810 - 31,193,586 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2631,166,593 - 31,193,587 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2631,118,870 - 31,149,720 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02632,568,771 - 32,599,639 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2632,568,771 - 32,599,645 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12630,617,044 - 30,647,882 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02630,241,110 - 30,271,944 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02631,331,626 - 31,362,486 (-)NCBIUU_Cfam_GSD_1.0
PPM1F
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1450,040,663 - 50,063,325 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11450,040,612 - 50,083,047 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21453,483,164 - 53,505,869 (+)NCBISscrofa10.2Sscrofa10.2susScr3
PPM1F
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1194,167,925 - 4,200,550 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl194,167,908 - 4,200,953 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660852,802,752 - 2,835,380 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Ppm1f
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247471,420,835 - 1,446,143 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247471,417,004 - 1,446,211 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression

RNA-SEQ Expression


Sequence


Ensembl Acc Id: ENSSTOT00000020828   ⟹   ENSSTOP00000023616
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
SpeTri2.0 EnsemblNW_0049366191,786,178 - 1,816,109 (+)Ensembl
Ensembl Acc Id: ENSSTOT00000032134   ⟹   ENSSTOP00000031361
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
SpeTri2.0 EnsemblNW_0049366191,786,265 - 1,816,109 (+)Ensembl
RefSeq Acc Id: XM_005334478   ⟹   XP_005334535
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_024405118140,937,979 - 140,967,837 (-)NCBI
SpeTri2.0NW_0049366191,786,223 - 1,816,083 (+)NCBI
Sequence:
RefSeq Acc Id: XM_013362514   ⟹   XP_013217968
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_024405118140,937,979 - 140,967,888 (-)NCBI
SpeTri2.0NW_0049366191,786,223 - 1,816,083 (+)NCBI
Sequence:
RefSeq Acc Id: XM_040289275   ⟹   XP_040145209
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_024405118140,937,979 - 140,967,812 (-)NCBI
Protein Sequences
Protein RefSeqs XP_005334535 (Get FASTA)   NCBI Sequence Viewer  
  XP_013217968 (Get FASTA)   NCBI Sequence Viewer  
  XP_040145209 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSSTOP00000023616.1
  ENSSTOP00000031361.1
GenBank Protein KAG3278753 (Get FASTA)   NCBI Sequence Viewer  
  KAG3278754 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: XP_005334535   ⟸   XM_005334478
- UniProtKB: I3NGW9 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_013217968   ⟸   XM_013362514
- UniProtKB: I3NGW9 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_040145209   ⟸   XM_040289275
- UniProtKB: I3NGW9 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSSTOP00000031361   ⟸   ENSSTOT00000032134
Ensembl Acc Id: ENSSTOP00000023616   ⟸   ENSSTOT00000020828
Protein Domains
PPM-type phosphatase


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSTOG00000020328 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSSTOT00000020828.2 UniProtKB/TrEMBL
  ENSSTOT00000032134.1 UniProtKB/TrEMBL
Gene3D-CATH 3.60.40.10 UniProtKB/TrEMBL
InterPro PP2C UniProtKB/TrEMBL
  PP2C_BS UniProtKB/TrEMBL
  PPM-type_dom_sf UniProtKB/TrEMBL
  PPM-type_phosphatase_dom UniProtKB/TrEMBL
NCBI Gene Ppm1f ENTREZGENE
PANTHER PROTEIN PHOSPHATASE 1F UniProtKB/TrEMBL
  PTHR13832 UniProtKB/TrEMBL
Pfam PP2C UniProtKB/TrEMBL
PROSITE PPM_1 UniProtKB/TrEMBL
  PPM_2 UniProtKB/TrEMBL
SMART PP2C_SIG UniProtKB/TrEMBL
  PP2Cc UniProtKB/TrEMBL
Superfamily-SCOP SSF81606 UniProtKB/TrEMBL
UniProt I3NGW9 ENTREZGENE, UniProtKB/TrEMBL