Ppm1f (protein phosphatase, Mg2+/Mn2+ dependent 1F) - Rat Genome Database

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Gene: Ppm1f (protein phosphatase, Mg2+/Mn2+ dependent 1F) Chinchilla lanigera
Analyze
Symbol: Ppm1f
Name: protein phosphatase, Mg2+/Mn2+ dependent 1F
RGD ID: 8895770
Description: ENCODES a protein that exhibits calmodulin-dependent protein phosphatase activity (ortholog); phosphoprotein phosphatase activity (ortholog); protein serine/threonine phosphatase activity (ortholog); INVOLVED IN cellular response to xenobiotic stimulus (ortholog); intrinsic apoptotic signaling pathway (ortholog); negative regulation of cell-cell adhesion mediated by cadherin (ortholog); PARTICIPATES IN adenosine monophosphate-activated protein kinase (AMPK) signaling pathway; calcium/calmodulin dependent kinase 2 signaling pathway; ASSOCIATED WITH chromosome 22q11.2 deletion syndrome, distal (ortholog); DiGeorge syndrome (ortholog); genetic disease (ortholog); FOUND IN cytosol (ortholog); perinuclear region of cytoplasm (ortholog); protein-containing complex (ortholog)
Type: protein-coding
RefSeq Status: MODEL
RGD Orthologs
Human
Mouse
Rat
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: ChiLan1.0 - Chinchilla ChiLan1.0 Assembly
NCBI Annotation Information: Annotation category: partial on reference assembly
Position:
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495544217,227,723 - 17,252,383 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495544217,233,258 - 17,256,009 (+)NCBIChiLan1.0ChiLan1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

References

References - curated
# Reference Title Reference Citation
1. Transitive Annotation Pipeline Automated assignment of GO, PW and RDO ISO annotations across species
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Ppm1f
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495544217,227,723 - 17,252,383 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495544217,233,258 - 17,256,009 (+)NCBIChiLan1.0ChiLan1.0
PPM1F
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382221,919,425 - 21,952,848 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2221,919,425 - 21,952,848 (-)EnsemblGRCh38hg38GRCh38
GRCh372222,273,798 - 22,307,220 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 362220,603,793 - 20,637,217 (-)NCBINCBI36Build 36hg18NCBI36
Build 342220,598,346 - 20,631,771NCBI
Celera226,091,333 - 6,124,791 (-)NCBICelera
Cytogenetic Map22q11.22NCBI
HuRef225,230,870 - 5,264,327 (-)NCBIHuRef
CHM1_12222,273,889 - 22,307,348 (-)NCBICHM1_1
T2T-CHM13v2.02222,332,962 - 22,366,379 (-)NCBIT2T-CHM13v2.0
Ppm1f
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391616,714,314 - 16,745,239 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1616,714,333 - 16,745,228 (+)EnsemblGRCm39 Ensembl
GRCm381616,896,469 - 16,927,375 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1616,896,469 - 16,927,364 (+)EnsemblGRCm38mm10GRCm38
MGSCv371616,903,414 - 16,927,455 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361616,816,884 - 16,840,925 (+)NCBIMGSCv36mm8
Celera1617,475,388 - 17,499,499 (+)NCBICelera
Cytogenetic Map16A3NCBI
cM Map1610.48NCBI
Ppm1f
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81197,568,627 - 97,598,613 (-)NCBIGRCr8
mRatBN7.21184,064,422 - 84,094,410 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1184,064,420 - 84,094,340 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1192,790,922 - 92,818,479 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01185,452,053 - 85,479,612 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01184,505,643 - 84,533,204 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01188,313,709 - 88,343,726 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1188,313,709 - 88,343,627 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01191,368,795 - 91,398,731 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41186,086,968 - 86,114,278 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11186,127,564 - 86,154,875 (-)NCBI
Celera1182,821,775 - 82,848,989 (-)NCBICelera
Cytogenetic Map11q23NCBI
PPM1F
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22331,461,495 - 31,494,626 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12234,010,360 - 34,043,505 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0224,039,032 - 4,072,165 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12220,520,022 - 20,553,128 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2220,520,022 - 20,553,128 (-)Ensemblpanpan1.1panPan2
PPM1F
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12631,162,810 - 31,193,586 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2631,166,593 - 31,193,587 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2631,118,870 - 31,149,720 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02632,568,771 - 32,599,639 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2632,568,771 - 32,599,645 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12630,617,044 - 30,647,882 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02630,241,110 - 30,271,944 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02631,331,626 - 31,362,486 (-)NCBIUU_Cfam_GSD_1.0
Ppm1f
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405118140,937,979 - 140,967,888 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049366191,786,178 - 1,816,109 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049366191,786,223 - 1,816,083 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
PPM1F
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1450,040,663 - 50,063,325 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11450,040,612 - 50,083,047 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21453,483,164 - 53,505,869 (+)NCBISscrofa10.2Sscrofa10.2susScr3
PPM1F
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1194,167,925 - 4,200,550 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl194,167,908 - 4,200,953 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660852,802,752 - 2,835,380 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Ppm1f
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247471,420,835 - 1,446,143 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247471,417,004 - 1,446,211 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSCLAT00000023020   ⟹   ENSCLAP00000022809
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0 EnsemblNW_00495544217,227,723 - 17,252,383 (+)Ensembl
RefSeq Acc Id: XM_013517654   ⟹   XP_013373108
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_00495544217,233,258 - 17,256,009 (+)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_013373108 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSCLAP00000022809
  ENSCLAP00000022809.1
Reference Protein Sequences
RefSeq Acc Id: XP_013373108   ⟸   XM_013517654
- UniProtKB: A0A8C2W6X6 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSCLAP00000022809   ⟸   ENSCLAT00000023020
Protein Domains
PPM-type phosphatase


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCLAG00000015644 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCLAT00000023020 ENTREZGENE
  ENSCLAT00000023020.1 UniProtKB/TrEMBL
Gene3D-CATH 3.60.40.10 UniProtKB/TrEMBL
InterPro PP2C UniProtKB/TrEMBL
  PP2C_BS UniProtKB/TrEMBL
  PPM-type_dom_sf UniProtKB/TrEMBL
  PPM-type_phosphatase_dom UniProtKB/TrEMBL
NCBI Gene Ppm1f ENTREZGENE
PANTHER PROTEIN PHOSPHATASE 1F UniProtKB/TrEMBL
  PTHR13832 UniProtKB/TrEMBL
Pfam PP2C UniProtKB/TrEMBL
PROSITE PPM_1 UniProtKB/TrEMBL
  PPM_2 UniProtKB/TrEMBL
SMART PP2C_SIG UniProtKB/TrEMBL
  PP2Cc UniProtKB/TrEMBL
Superfamily-SCOP SSF81606 UniProtKB/TrEMBL
UniProt A0A8C2W6X6 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-08-16 Ppm1f  protein phosphatase, Mg2+/Mn2+ dependent 1F    protein phosphatase, Mg2+/Mn2+ dependent, 1F  Symbol and/or name change 5135510 APPROVED