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Gene: PPM1F (protein phosphatase, Mg2+/Mn2+ dependent 1F) Homo sapiens
Symbol: PPM1F
Name: protein phosphatase, Mg2+/Mn2+ dependent 1F
Description: Exhibits calmodulin-dependent protein phosphatase activity and protein tyrosine/serine/threonine phosphatase activity. Involved in several processes, including positive regulation of cellular component biogenesis; protein dephosphorylation; and regulation of cellular protein metabolic process. Localizes to cytosol and protein-containing complex.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: Ca(2+)/calmodulin-dependent protein kinase phosphatase; CaM-kinase phosphatase; CAMKP; CaMKPase; FEM-2; hFEM-2; KIAA0015; partner of PIX 2; POPX2; PP2C phosphatase; protein fem-2 homolog; protein phosphatase 1F; protein phosphatase 1F (PP2C domain containing)
Mus musculus (house mouse) : Ppm1f (protein phosphatase 1F (PP2C domain containing))  MGI  Alliance
Rattus norvegicus (Norway rat) : Ppm1f (protein phosphatase, Mg2+/Mn2+ dependent, 1F)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Ppm1f (protein phosphatase, Mg2+/Mn2+ dependent 1F)
Pan paniscus (bonobo/pygmy chimpanzee) : PPM1F (protein phosphatase, Mg2+/Mn2+ dependent 1F)
Canis lupus familiaris (dog) : PPM1F (protein phosphatase, Mg2+/Mn2+ dependent 1F)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Ppm1f (protein phosphatase, Mg2+/Mn2+ dependent 1F)
Sus scrofa (pig) : PPM1F (protein phosphatase, Mg2+/Mn2+ dependent 1F)
Chlorocebus sabaeus (African green monkey) : PPM1F (protein phosphatase, Mg2+/Mn2+ dependent 1F)
Heterocephalus glaber (naked mole-rat) : Ppm1f (protein phosphatase, Mg2+/Mn2+ dependent 1F)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38.p13 Ensembl2221,919,425 - 21,952,848 (-)EnsemblGRCh38hg38GRCh38
GRCh382221,919,419 - 21,952,875 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh372222,273,792 - 22,307,250 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 362220,603,793 - 20,637,217 (-)NCBINCBI36hg18NCBI36
Build 342220,598,346 - 20,631,771NCBI
Celera226,091,333 - 6,124,791 (-)NCBI
Cytogenetic Map22q11.22NCBI
HuRef225,230,870 - 5,264,327 (-)NCBIHuRef
CHM1_12222,273,889 - 22,307,348 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
Nomenclature History
More on PPM1F
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 737169
Created: 2004-02-06
Species: Homo sapiens
Last Modified: 2020-08-04
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.