Fbxo5 (F-box protein 5) - Rat Genome Database

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Gene: Fbxo5 (F-box protein 5) Ictidomys tridecemlineatus
Analyze
Symbol: Fbxo5
Name: F-box protein 5
RGD ID: 12549049
Description: ENCODES a protein that exhibits anaphase-promoting complex binding (inferred); metal ion binding (inferred); molecular function inhibitor activity (inferred); INVOLVED IN microtubule polymerization (ortholog); negative regulation of meiotic nuclear division (ortholog); negative regulation of ubiquitin protein ligase activity (ortholog); ASSOCIATED WITH autosomal recessive spinocerebellar ataxia 8 (ortholog); chromosome 6q24-q25 deletion syndrome (ortholog); FOUND IN cytoplasm (inferred); meiotic spindle (inferred); nucleoplasm (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: F-box only protein 5
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: SpeTri2.0 - Squirrel SpeTri2.0 Assembly
Position:
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024404946138,337,977 - 138,349,305 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049364895,589,538 - 5,600,539 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049364895,589,621 - 5,602,221 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
cytoplasm  (IEA)
meiotic spindle  (IEA)
nucleoplasm  (IEA)
nucleus  (IEA)
spindle  (IEA)

Molecular Function

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Fbxo5
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024404946138,337,977 - 138,349,305 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049364895,589,538 - 5,600,539 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049364895,589,621 - 5,602,221 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
FBXO5
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh386152,970,535 - 152,983,579 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl6152,970,519 - 152,983,579 (-)EnsemblGRCh38hg38GRCh38
GRCh376153,291,670 - 153,304,714 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 366153,333,351 - 153,345,867 (-)NCBINCBI36Build 36hg18NCBI36
Build 346153,383,773 - 153,396,288NCBI
Celera6154,025,328 - 154,038,410 (-)NCBICelera
Cytogenetic Map6q25.2NCBI
HuRef6150,854,447 - 150,867,531 (-)NCBIHuRef
CHM1_16153,555,576 - 153,568,660 (-)NCBICHM1_1
T2T-CHM13v2.06154,171,829 - 154,184,878 (-)NCBIT2T-CHM13v2.0
Fbxo5
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39105,749,155 - 5,755,465 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl105,749,160 - 5,755,600 (-)EnsemblGRCm39 Ensembl
GRCm38105,799,158 - 5,805,465 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl105,799,160 - 5,805,600 (-)EnsemblGRCm38mm10GRCm38
MGSCv37104,541,076 - 4,547,383 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36104,541,076 - 4,546,998 (+)NCBIMGSCv36mm8
Celera105,733,112 - 5,739,409 (-)NCBICelera
Cytogenetic Map10A1NCBI
cM Map101.91NCBI
Fbxo5
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8144,601,412 - 44,607,781 (-)NCBIGRCr8
mRatBN7.2142,196,068 - 42,202,437 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl142,196,068 - 42,202,437 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx142,738,271 - 42,744,646 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0148,725,464 - 48,731,839 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0142,813,736 - 42,820,111 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0142,461,277 - 42,467,646 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl142,461,291 - 42,467,586 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0143,791,187 - 43,797,556 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4136,492,134 - 36,498,503 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1136,495,551 - 36,501,323 (-)NCBI
Celera137,863,352 - 37,869,721 (-)NCBICelera
Cytogenetic Map1q11NCBI
Fbxo5
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554398,830,975 - 8,843,828 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554398,830,658 - 8,843,653 (+)NCBIChiLan1.0ChiLan1.0
FBXO5
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v25172,999,614 - 173,012,769 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan16170,892,462 - 170,905,617 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v06150,793,020 - 150,806,008 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.16155,481,767 - 155,494,689 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl6155,481,753 - 155,494,231 (-)Ensemblpanpan1.1panPan2
FBXO5
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1143,138,338 - 43,149,546 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl143,138,889 - 43,149,297 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha143,975,851 - 43,987,186 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0143,321,686 - 43,333,047 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl143,322,263 - 43,332,336 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1143,189,124 - 43,200,485 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0143,052,605 - 43,063,915 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0143,540,287 - 43,551,650 (-)NCBIUU_Cfam_GSD_1.0
FBXO5
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl113,467,501 - 13,505,928 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1113,466,961 - 13,478,496 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2115,716,714 - 15,728,617 (+)NCBISscrofa10.2Sscrofa10.2susScr3
FBXO5
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11380,453,345 - 80,467,590 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1380,453,355 - 80,466,778 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604052,778,853 - 52,792,908 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Fbxo5
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247855,247,731 - 5,260,736 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247855,248,434 - 5,260,623 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression

RNA-SEQ Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts XM_005321383 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide JAESOR010000005 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSSTOT00000027414   ⟹   ENSSTOP00000015124
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
SpeTri2.0 EnsemblNW_0049364895,589,538 - 5,600,539 (-)Ensembl
RefSeq Acc Id: XM_005321383   ⟹   XP_005321440
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_024404946138,337,977 - 138,349,305 (-)NCBI
SpeTri2.0NW_0049364895,589,621 - 5,602,221 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_005321440 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSSTOP00000015124.2
GenBank Protein KAG3290475 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: XP_005321440   ⟸   XM_005321383
- UniProtKB: I3MSM9 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSSTOP00000015124   ⟸   ENSSTOT00000027414
Protein Domains
ZBR-type


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSTOG00000029069 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSSTOT00000027414.2 UniProtKB/TrEMBL
Gene3D-CATH 1.20.1280.50 UniProtKB/TrEMBL
  2.20.25.20 UniProtKB/TrEMBL
InterPro F-box-like_dom_sf UniProtKB/TrEMBL
  F-box_dom UniProtKB/TrEMBL
  FBX5_43 UniProtKB/TrEMBL
  ZF_ZBR UniProtKB/TrEMBL
NCBI Gene Fbxo5 ENTREZGENE
PANTHER F-BOX ONLY PROTEIN 5 UniProtKB/TrEMBL
  F-BOX ONLY PROTEIN 5 AND 43 UniProtKB/TrEMBL
Pfam F-box UniProtKB/TrEMBL
  IBR_1 UniProtKB/TrEMBL
PROSITE PROKAR_LIPOPROTEIN UniProtKB/TrEMBL
  ZF_ZBR UniProtKB/TrEMBL
Superfamily-SCOP SSF81383 UniProtKB/TrEMBL
UniProt I3MSM9 ENTREZGENE, UniProtKB/TrEMBL