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Gene: Cops5 (COP9 signalosome subunit 5) Ictidomys tridecemlineatus

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Symbol:

Cops5

Name:

COP9 signalosome subunit 5

RGD ID:

12534558

Description:

ENCODES a protein that exhibits enzyme binding (inferred); macrophage migration inhibitory factor binding (inferred); metal-dependent deubiquitinase activity (inferred); INVOLVED IN positive regulation of apoptotic process (ortholog); positive regulation of DNA-binding transcription factor activity (ortholog); PARTICIPATES IN hypoxia inducible factor pathway; ASSOCIATED WITH Experimental Liver Neoplasms (ortholog); hepatocellular carcinoma (ortholog); Joubert syndrome 21 (ortholog); FOUND IN mitochondrion (ortholog)

Type:

protein-coding

RefSeq Status:

MODEL

Previously known as:

COP9 signalosome complex subunit 5; COP9 signalosome subunit 5, transcript variant X1; COP9 signalosome subunit 5, transcript variant X2

RGD Orthologs

Alliance Orthologs

More Info

more info ...

Latest Assembly:

SpeTri2.0 - Squirrel SpeTri2.0 Assembly

Position:

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024405303	67,734,939 - 67,749,504 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936496	7,035,924 - 7,050,786 (+)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936496	7,035,973 - 7,050,538 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Only show annotations with direct experimental evidence (0 objects hidden)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
Cops5	Squirrel	Experimental Liver Neoplasms		ISO	Cops5 (Rattus norvegicus)	9068941	protein:increased expression:liver (rat)	RGD	PMID:26606000 and REF_RGD_ID:11354707
Cops5	Squirrel	hepatocellular carcinoma	severity	ISO	COPS5 (Homo sapiens)	9068941	protein:increased expression:liver (human)	RGD	PMID:26606000 and REF_RGD_ID:11354707

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
Cops5	Squirrel	Joubert syndrome 21		ISO	COPS5 (Homo sapiens)	8554872	ClinVar Annotator: match by term: Joubert syndrome 21	ClinVar	PMID:28492532

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
Cops5	Squirrel	hepatocellular carcinoma		ISO	COPS5 (Homo sapiens)	9068941	CTD Direct Evidence: marker/mechanism	CTD	PMID:20698225
Cops5	Squirrel	Stevens-Johnson syndrome		ISO	COPS5 (Homo sapiens)	9068941	CTD Direct Evidence: marker/mechanism	CTD	PMID:25811541

Biological Process

Only show annotations with direct experimental evidence (0 objects hidden)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
Cops5	Squirrel	exosomal secretion	involved_in	IEA	UniProtKB:Q92905 and ensembl:ENSP00000350512	150520179		Ensembl	GO_REF:0000107
Cops5	Squirrel	negative regulation of apoptotic process	involved_in	IEA	UniProtKB:Q92905 and ensembl:ENSP00000350512	150520179		Ensembl	GO_REF:0000107
Cops5	Squirrel	positive regulation of apoptotic process	involved_in	ISO	COPS5 (Sus scrofa)	9068941	PMID:24091666	AgBase	PMID:24091666
Cops5	Squirrel	positive regulation of DNA-binding transcription factor activity	involved_in	ISO	COPS5 (Homo sapiens)	9068941	PMID:20978819	UniProt	PMID:20978819
Cops5	Squirrel	positive regulation of transcription by RNA polymerase II	involved_in	IEA	UniProtKB:Q92905 and ensembl:ENSP00000350512	150520179		Ensembl	GO_REF:0000107
Cops5	Squirrel	protein deneddylation	involved_in	IEA	UniProtKB:Q92905 and ensembl:ENSP00000350512	150520179		Ensembl	GO_REF:0000107
Cops5	Squirrel	regulation of cell cycle	acts_upstream_of_or_within	IEA	UniProtKB:O35864 and ensembl:ENSMUSP00000027050	150520179		Ensembl	GO_REF:0000107
Cops5	Squirrel	regulation of IRE1-mediated unfolded protein response	involved_in	IEA	UniProtKB:Q92905 and ensembl:ENSP00000350512	150520179		Ensembl	GO_REF:0000107
Cops5	Squirrel	regulation of JNK cascade	involved_in	IEA	UniProtKB:Q92905 and ensembl:ENSP00000350512	150520179		Ensembl	GO_REF:0000107

Cellular Component

Only show annotations with direct experimental evidence (0 objects hidden)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
Cops5	Squirrel	chromatin	located_in	IEA	UniProtKB:Q92905 and ensembl:ENSP00000350512	150520179		Ensembl	GO_REF:0000107
Cops5	Squirrel	COP9 signalosome	part_of	IEA	UniProtKB-KW:KW-0736	150520179		UniProt	GO_REF:0000043
Cops5	Squirrel	COP9 signalosome	part_of	IEA	UniProtKB:O35864 more ...	150520179		Ensembl	GO_REF:0000107
Cops5	Squirrel	cytoplasm	located_in	IEA	UniProtKB:Q92905 and ensembl:ENSP00000350512	150520179		Ensembl	GO_REF:0000107
Cops5	Squirrel	cytosol	located_in	IEA	UniProtKB:Q92905 and ensembl:ENSP00000350512	150520179		Ensembl	GO_REF:0000107
Cops5	Squirrel	mitochondrion	located_in	ISO	COPS5 (Sus scrofa)	9068941	PMID:24091666	AgBase	PMID:24091666
Cops5	Squirrel	nucleoplasm	located_in	IEA	UniProtKB:A0A024R7W9 more ...	150520179		Ensembl	GO_REF:0000107
Cops5	Squirrel	nucleus	located_in	IEA	UniProtKB:Q92905 and ensembl:ENSP00000350512	150520179		Ensembl	GO_REF:0000107
Cops5	Squirrel	perinuclear region of cytoplasm	located_in	IEA	UniProtKB:Q92905 and ensembl:ENSP00000350512	150520179		Ensembl	GO_REF:0000107
Cops5	Squirrel	synaptic vesicle	located_in	IEA	UniProtKB:Q92905 and ensembl:ENSP00000350512	150520179		Ensembl	GO_REF:0000107

Molecular Function

Only show annotations with direct experimental evidence (0 objects hidden)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
Cops5	Squirrel	enzyme binding	enables	IEA	UniProtKB:O35864 and ensembl:ENSMUSP00000027050	150520179		Ensembl	GO_REF:0000107
Cops5	Squirrel	macrophage migration inhibitory factor binding	enables	IEA	UniProtKB:O35864 and ensembl:ENSMUSP00000027050	150520179		Ensembl	GO_REF:0000107
Cops5	Squirrel	metal-dependent deubiquitinase activity	enables	IEA	UniProtKB:Q92905 and ensembl:ENSP00000350512	150520179		Ensembl	GO_REF:0000107
Cops5	Squirrel	metallopeptidase activity	enables	IEA	InterPro:IPR000555	150520179		InterPro	GO_REF:0000002
Cops5	Squirrel	metallopeptidase activity	enables	IEA	UniProtKB-KW:KW-0482	150520179		UniProt	GO_REF:0000043
Cops5	Squirrel	metallopeptidase activity	enables	IEA	UniProtKB:Q92905 and ensembl:ENSP00000350512	150520179		Ensembl	GO_REF:0000107
Cops5	Squirrel	peptidase activity	enables	IEA	InterPro:IPR000555	150520179		InterPro	GO_REF:0000002
Cops5	Squirrel	protein binding	enables	ISO	UniProtKB:O75460	9068941	PMID:15234121	ParkinsonsUK-UCL	PMID:15234121
Cops5	Squirrel	protein binding	enables	ISO	PR:O88543 more ...	9068941	PMID:9707402	MGI	PMID:9707402
Cops5	Squirrel	protein binding	enables	ISO	UniProtKB:P10599 and UniProtKB:P46527	9068941	PMID:15480426	IntAct	PMID:15480426
Cops5	Squirrel	protein binding	enables	ISO	UniProtKB:Q7L5N1	9068941	PMID:21625211	IntAct	PMID:21625211
Cops5	Squirrel	protein binding	enables	ISO	UniProtKB:Q13098	9068941	PMID:19444310 and PMID:27029275	IntAct	PMID:19444310 and PMID:27029275
Cops5	Squirrel	protein binding	enables	ISO	UniProtKB:P09936 and UniProtKB:P46527	9068941	PMID:12082530	IntAct	PMID:12082530
Cops5	Squirrel	protein binding	enables	ISO	UniProtKB:Q7L5N1 and UniProtKB:Q9UNS2	9068941	PMID:25043011 and PMID:28514442	IntAct	PMID:25043011 and PMID:28514442
Cops5	Squirrel	protein binding	enables	ISO	UniProtKB:Q13098 and UniProtKB:Q9UNS2	9068941	PMID:24421388	IntAct	PMID:24421388
Cops5	Squirrel	protein binding	enables	ISO	UniProtKB:O15105	9068941	PMID:14993265	IntAct	PMID:14993265
Cops5	Squirrel	protein binding	enables	ISO	PR:Q9JLI7	9068941	PMID:31146259	MGI	PMID:31146259
Cops5	Squirrel	protein binding	enables	ISO	UniProtKB:Q13098 more ...	9068941	PMID:20399188	IntAct	PMID:20399188
Cops5	Squirrel	protein binding	enables	ISO	UniProtKB:P10599 more ...	9068941	PMID:21145461	IntAct	PMID:21145461
Cops5	Squirrel	protein binding	enables	ISO	UniProtKB:Q13618	9068941	PMID:37207277	IntAct	PMID:37207277
Cops5	Squirrel	protein binding	enables	ISO	UniProtKB:Q8WXC6	9068941	PMID:26456823	UniProt	PMID:26456823
Cops5	Squirrel	protein binding	enables	ISO	UniProtKB:Q13098 more ...	9068941	PMID:18850735 more ...	IntAct	PMID:18850735 more ...
Cops5	Squirrel	protein binding	enables	ISO	UniProtKB:O95273	9068941	PMID:15887118	IntAct	PMID:15887118
Cops5	Squirrel	protein binding	enables	ISO	UniProtKB:P55085	9068941	PMID:16410250	IntAct	PMID:16410250
Cops5	Squirrel	protein binding	enables	ISO	UniProtKB:Q9H8M7	9068941	PMID:21499297	IntAct	PMID:21499297
Cops5	Squirrel	protein binding	enables	ISO	UniProtKB:O14879	9068941	PMID:17050680	IntAct	PMID:17050680
Cops5	Squirrel	protein binding	enables	ISO	UniProtKB:P35372	9068941	PMID:23840749	IntAct	PMID:23840749
Cops5	Squirrel	protein binding	enables	ISO	UniProtKB:Q8TC84	9068941	PMID:20978819	UniProt	PMID:20978819
Cops5	Squirrel	protein binding	enables	ISO	UniProtKB:O60356	9068941	PMID:16300740	UniProt	PMID:16300740
Cops5	Squirrel	protein binding	enables	ISO	UniProtKB:Q969Y2	9068941	PMID:32296183	IntAct	PMID:32296183
Cops5	Squirrel	protein binding	enables	ISO	UniProtKB:Q5VTR2	9068941	PMID:19214193	IntAct	PMID:19214193
Cops5	Squirrel	protein binding	enables	ISO	UniProtKB:Q8WXC6-2	9068941	PMID:23776465	UniProt	PMID:23776465
Cops5	Squirrel	protein binding	enables	ISO	UniProtKB:Q8IWQ3	9068941	PMID:22609399	IntAct	PMID:22609399

Imported Annotations - PID (archival)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
Cops5	Squirrel	hypoxia inducible factor pathway		ISO	COPS5 (Homo sapiens)	9068941		PID	PID:200202

PMID:22301074	PMID:30032202

Cops5
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024405303	67,734,939 - 67,749,504 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936496	7,035,924 - 7,050,786 (+)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936496	7,035,973 - 7,050,538 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

COPS5
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	8	67,043,079 - 67,062,133 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	8	67,043,079 - 67,083,783 (-)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	8	67,955,314 - 67,974,368 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	8	68,117,868 - 68,137,116 (-)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	8	68,117,869 - 68,137,116	NCBI
Celera	8	63,948,870 - 63,967,877 (-)	NCBI		Celera
Cytogenetic Map	8	q13.1	NCBI
HuRef	8	63,447,901 - 63,467,140 (-)	NCBI		HuRef
CHM1_1	8	68,010,363 - 68,029,584 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	8	67,469,560 - 67,488,599 (-)	NCBI		T2T-CHM13v2.0

Cops5
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	1	10,094,825 - 10,108,384 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	1	10,094,826 - 10,108,393 (-)	Ensembl		GRCm39 Ensembl
GRCm38	1	10,024,600 - 10,038,159 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	1	10,024,601 - 10,038,168 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	1	10,014,911 - 10,027,979 (-)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	1	10,010,044 - 10,023,120 (-)	NCBI		MGSCv36	mm8
Celera	1	9,998,994 - 10,012,139 (-)	NCBI		Celera
Cytogenetic Map	1	A2	NCBI
cM Map	1	2.29	NCBI

Cops5
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	5	13,975,198 - 13,993,391 (+)	NCBI		GRCr8
mRatBN7.2	5	9,192,233 - 9,210,498 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	5	9,192,100 - 9,210,731 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	5	11,344,273 - 11,362,693 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	5	12,971,568 - 12,989,792 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	5	12,678,930 - 12,697,346 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	5	8,876,090 - 8,894,345 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	5	8,876,044 - 8,894,339 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	5	13,684,111 - 13,702,378 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	5	8,709,214 - 8,727,277 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	5	8,709,213 - 8,727,277 (+)	NCBI
Celera	5	8,703,366 - 8,721,421 (+)	NCBI		Celera
Cytogenetic Map	5	q11	NCBI

Cops5
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955444	12,217,337 - 12,234,193 (+)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955444	12,217,337 - 12,233,570 (+)	NCBI	ChiLan1.0	ChiLan1.0

COPS5
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	7	82,780,377 - 82,802,763 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	8	58,422,637 - 58,444,975 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	8	63,586,062 - 63,605,213 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	8	65,247,796 - 65,266,736 (-)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	8	65,247,950 - 65,266,511 (-)	Ensembl	panpan1.1		panPan2

COPS5
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	29	16,562,234 - 16,579,082 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	29	16,562,234 - 16,578,847 (-)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	29	16,878,268 - 16,895,114 (-)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	29	16,643,359 - 16,660,206 (-)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	29	16,643,362 - 16,660,004 (-)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	29	16,674,884 - 16,691,721 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	29	16,775,204 - 16,792,055 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	29	17,031,587 - 17,048,439 (-)	NCBI		UU_Cfam_GSD_1.0

COPS5
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	4	67,739,251 - 67,758,150 (+)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	4	67,740,528 - 67,758,153 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	4	73,801,311 - 73,818,936 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

COPS5
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	8	62,905,924 - 62,925,205 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	8	62,905,906 - 62,925,201 (-)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666039	78,579,728 - 78,598,284 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Cops5
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624744	24,287,443 - 24,308,024 (+)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624744	24,287,278 - 24,308,171 (+)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.


RefSeq Transcripts	XM_005322940	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_021724899	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	JAESOR010000362	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSSTOT00000007289 ⟹ ENSSTOP00000006513

Type:

CODING

Position:

Squirrel Assembly	Chr	Position (strand)	Source
SpeTri2.0 Ensembl	NW_004936496	7,035,924 - 7,050,786 (+)	Ensembl

RefSeq Acc Id:

XM_005322940 ⟹ XP_005322997

Type:

CODING

Position:

Squirrel Assembly	Chr	Position (strand)	Source
HiC_Itri_2	NW_024405303	67,734,939 - 67,749,504 (-)	NCBI
SpeTri2.0	NW_004936496	7,035,973 - 7,050,538 (+)	NCBI

Sequence:

show sequence

CCATTCTCAAATAGAATCATTGTGTTTGTCCTAATTCACACATAATTCACACAGTTTTCCTAGACAGTAACTTCTCCTTTCAACCACAAGACTTCTTCTCTCCATAATTTTTAAAGTAATCGCTTTTT
ACATAGTCGTGTTTCAAAAGAGAAACGTGTCTCCCCTGCCATTCCGAATGGTATGTGCAGACCTCACCTCCGGTGTTAGGTGTCATGGATGCCCCGAGAGTCTAGTAAGAATTTGCACCCGTGGTGGG
GAAGGTCTGAAGCCCACACCTGAAAACCCAGTGAAGTAAAGTTGCGTTTTGGTTGTGGAAGTGACAACTTCTCCGATTCCTCGGCGATGGCGGCGTCCGGGAGCGGTATGGCCCAGAAAACCTGGGAA
TTGGCCAACAACATGCAAGAAGCCCAGAGTATTGATGAAATCTACAAATACGACAAAAAACAGCAGCAAGAAATCCTGGCGGCGAAACCCTGGACTAAGGATCACCATTACTTTAAATACTGCAAAAT
CTCAGCTTTGGCTCTACTAAAAATGGTGATGCATGCCAGATCAGGAGGCAACTTGGAAGTGATGGGTTTGATGCTAGGAAAGGTGGACGGTGAAACCATGATCATTATGGACAGTTTTGCTTTGCCTG
TAGAGGGCACTGAAACCCGAGTAAATGCTCAGGCTGCTGCATATGAGTACATGGCTGCATACATAGAAAACGCCAAACAGGTTGGTCGCCTTGAAAATGCAATTGGCTGGTACCATAGCCACCCTGGC
TATGGCTGCTGGCTTTCTGGGATTGATGTTAGTACACAGATGCTTAACCAGCAGTTCCAAGAACCATTCGTAGCAGTGGTAATTGATCCAACAAGAACAATATCTGCAGGAAAAGTGAATCTTGGAGC
CTTTAGGACATACCCAAAGGGCTACAAACCTCCTGATGAAGGACCTTCTGAATACCAAACTATTCCACTCAACAAAATAGAAGACTTTGGTGTACATTGCAAACAATACTATGCCTTAGAAGTCTCAT
ATTTCAAATCCTCTTTGGATCGCAAATTACTTGAGCTTTTGTGGAATAAATACTGGGTGAATACACTGAGTTCCTCTAGCTTGCTTACTAATGCAGACTATACCACTGGTCAGGTGTTTGATTTGTCT
GAAAAGTTAGAGCAGTCAGAAGCTCAGCTGGGCCGAGGGAGTTTCATGTTGGGTTTAGAAACACATGATCGAAAGTCAGAAGACAAACTTGCCAAAGCTACAAGAGACAGCTGTAAAACCACCATAGA
AGCCATCCATGGATTGATGTCTCAGGTTATTAAGGATAAACTGTTTAATCAAATTAACATCTCTTAAACAGTCACTGACAGTACTTTTGCCTGAAAACTGGTATGCGGAAAAATACTCAAGTAATACT
TTTAAAACCAGTTACCAAAAATCTGATTAGAAGTATAAGGTGCTCTGAAATGTCCTGAATATTAACATCCTGTAATAAAACTCTATAAAATGAAA

hide sequence

RefSeq Acc Id:

XM_021724899 ⟹ XP_021580574

Type:

CODING

Position:

Squirrel Assembly	Chr	Position (strand)	Source
HiC_Itri_2	NW_024405303	67,734,939 - 67,749,150 (-)	NCBI
SpeTri2.0	NW_004936496	7,036,393 - 7,050,538 (+)	NCBI

Sequence:

show sequence

GAAATCTACAAATACGACAAAAAACAGCAGCAAGAAATCCTGGCGGCGAAACCCTGGACTAAGGAGTGAGGAGTCACCATTACTTTAAATACTGCAAAATCTCAGCTTTGGCTCTACTAAAAATGGTG
ATGCATGCCAGATCAGGAGGCAACTTGGAAGTGATGGGTTTGATGCTAGGAAAGGTGGACGGTGAAACCATGATCATTATGGACAGTTTTGCTTTGCCTGTAGAGGGCACTGAAACCCGAGTAAATGC
TCAGGCTGCTGCATATGAGTACATGGCTGCATACATAGAAAACGCCAAACAGGTTGGTCGCCTTGAAAATGCAATTGGCTGGTACCATAGCCACCCTGGCTATGGCTGCTGGCTTTCTGGGATTGATG
TTAGTACACAGATGCTTAACCAGCAGTTCCAAGAACCATTCGTAGCAGTGGTAATTGATCCAACAAGAACAATATCTGCAGGAAAAGTGAATCTTGGAGCCTTTAGGACATACCCAAAGGGCTACAAA
CCTCCTGATGAAGGACCTTCTGAATACCAAACTATTCCACTCAACAAAATAGAAGACTTTGGTGTACATTGCAAACAATACTATGCCTTAGAAGTCTCATATTTCAAATCCTCTTTGGATCGCAAATT
ACTTGAGCTTTTGTGGAATAAATACTGGGTGAATACACTGAGTTCCTCTAGCTTGCTTACTAATGCAGACTATACCACTGGTCAGGTGTTTGATTTGTCTGAAAAGTTAGAGCAGTCAGAAGCTCAGC
TGGGCCGAGGGAGTTTCATGTTGGGTTTAGAAACACATGATCGAAAGTCAGAAGACAAACTTGCCAAAGCTACAAGAGACAGCTGTAAAACCACCATAGAAGCCATCCATGGATTGATGTCTCAGGTT
ATTAAGGATAAACTGTTTAATCAAATTAACATCTCTTAAACAGTCACTGACAGTACTTTTGCCTGAAAACTGGTATGCGGAAAAATACTCAAGTAATACTTTTAAAACCAGTTACCAAAAATCTGATT
AGAAGTATAAGGTGCTCTGAAATGTCCTGAATATTAACATCCTGTAATAAAACTCTATAAAATGAAA

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Protein RefSeqs	XP_005322997	(Get FASTA)	NCBI Sequence Viewer
	XP_021580574	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSSTOP00000006513.3
GenBank Protein	KAG3274111	(Get FASTA)	NCBI Sequence Viewer
	KAG3274112	(Get FASTA)	NCBI Sequence Viewer

RefSeq Acc Id:	XP_005322997 ⟸ XM_005322940
- Peptide Label:	isoform X1
- UniProtKB:	I3M9F6 (UniProtKB/TrEMBL)
- Sequence:	show sequence MAASGSGMAQKTWELANNMQEAQSIDEIYKYDKKQQQEILAAKPWTKDHHYFKYCKISALALLKMVMHARSGGNLEVMGLMLGKVDGETMIIMDSFALPVEGTETRVNAQAAAYEYMAAYIENAKQVG RLENAIGWYHSHPGYGCWLSGIDVSTQMLNQQFQEPFVAVVIDPTRTISAGKVNLGAFRTYPKGYKPPDEGPSEYQTIPLNKIEDFGVHCKQYYALEVSYFKSSLDRKLLELLWNKYWVNTLSSSSLL TNADYTTGQVFDLSEKLEQSEAQLGRGSFMLGLETHDRKSEDKLAKATRDSCKTTIEAIHGLMSQVIKDKLFNQINIS hide sequence

RefSeq Acc Id:

XP_021580574 ⟸ XM_021724899

- Peptide Label:

isoform X2

- Sequence:

show sequence

MVMHARSGGNLEVMGLMLGKVDGETMIIMDSFALPVEGTETRVNAQAAAYEYMAAYIENAKQVGRLENAIGWYHSHPGYGCWLSGIDVSTQMLNQQFQEPFVAVVIDPTRTISAGKVNLGAFRTYPKG
YKPPDEGPSEYQTIPLNKIEDFGVHCKQYYALEVSYFKSSLDRKLLELLWNKYWVNTLSSSSLLTNADYTTGQVFDLSEKLEQSEAQLGRGSFMLGLETHDRKSEDKLAKATRDSCKTTIEAIHGLMS
QVIKDKLFNQINIS

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Ensembl Acc Id:

ENSSTOP00000006513 ⟸ ENSSTOT00000007289

Protein Domains

MPN

Database	Acc Id	Source(s)
Ensembl Genes	ENSSTOG00000007290	Ensembl, UniProtKB/TrEMBL
Ensembl Transcript	ENSSTOT00000007289.3	UniProtKB/TrEMBL
Gene3D-CATH	Cytidine Deaminase, domain 2	UniProtKB/TrEMBL
InterPro	CSN5_C	UniProtKB/TrEMBL
	JAMM/MPN+_dom	UniProtKB/TrEMBL
	JAMM_MPN+_peptidase_M67A	UniProtKB/TrEMBL
	MPN	UniProtKB/TrEMBL
NCBI Gene	Cops5	ENTREZGENE
PANTHER	EUKARYOTIC TRANSLATION INITIATION FACTOR 3 -RELATED	UniProtKB/TrEMBL
Pfam	CSN5_C	UniProtKB/TrEMBL
	JAB	UniProtKB/TrEMBL
PROSITE	MPN	UniProtKB/TrEMBL
SMART	JAB_MPN	UniProtKB/TrEMBL
Superfamily-SCOP	JAB1/MPN domain	UniProtKB/TrEMBL
UniProt	I3M9F6	ENTREZGENE, UniProtKB/TrEMBL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailable


InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailable


Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
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MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable

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Imported Disease Annotations - CTD

Imported Annotations - PID (archival)

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Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD

Imported Annotations - PID (archival)