Zmynd8 (zinc finger MYND-type containing 8) - Rat Genome Database

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Gene: Zmynd8 (zinc finger MYND-type containing 8) Ictidomys tridecemlineatus
Analyze
Symbol: Zmynd8
Name: zinc finger MYND-type containing 8
RGD ID: 12532979
Description: ENCODES a protein that exhibits histone H3K14ac reader activity (ortholog); histone H3K4me1 reader activity (ortholog); INVOLVED IN modulation of excitatory postsynaptic potential (ortholog); positive regulation of dendritic spine development (ortholog); positive regulation of dendritic spine maintenance (ortholog); ASSOCIATED WITH focal epilepsy (ortholog); intellectual disability (ortholog); Neurodevelopmental Disorders (ortholog); FOUND IN dendritic shaft (ortholog); dendritic spine (ortholog)
Type: protein-coding
RefSeq Status: MODEL
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: SpeTri2.0 - Squirrel SpeTri2.0 Assembly
Position:
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024408640190,662,525 - 190,760,665 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365146,116,676 - 6,212,996 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365146,116,789 - 6,214,383 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Zmynd8Squirrelfocal epilepsy  ISOZMYND8 (Homo sapiens)8554872ClinVar Annotator: match by term: Focal-onset seizureClinVarPMID:32581362
Zmynd8Squirrelintellectual disability  ISOZMYND8 (Homo sapiens)8554872ClinVar Annotator: match by term: Intellectual disabilityClinVarPMID:25741868
Zmynd8SquirrelNeurodevelopmental Disorders  ISOZMYND8 (Homo sapiens)8554872ClinVar Annotator: match by term: Neurodevelopmental disorderClinVarPMID:25741868 more ...


Biological Process
1 to 13 of 13 rows

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Zmynd8Squirreldouble-strand break repair via homologous recombination involved_inIEAUniProtKB:Q9ULU4 and ensembl:ENSP00000420095150520179 EnsemblGO_REF:0000107
Zmynd8Squirrelmodulation of excitatory postsynaptic potential  ISOZmynd8 (Rattus norvegicus)9068941 RGDPMID:24117785 and REF_RGD_ID:8554267
Zmynd8Squirrelnegative regulation of cell migration involved_inIEAUniProtKB:Q9ULU4 and ensembl:ENSP00000420095150520179 EnsemblGO_REF:0000107
Zmynd8Squirrelnegative regulation of DNA-templated transcription involved_inIEAGO:0003714150520179 GOCGO_REF:0000108
Zmynd8Squirrelnegative regulation of transcription by RNA polymerase II involved_inIEAUniProtKB:Q9ULU4 and ensembl:ENSP00000420095150520179 EnsemblGO_REF:0000107
Zmynd8Squirrelnervous system development involved_inIEAUniProtKB:Q9ULU4 and ensembl:ENSP00000420095150520179 EnsemblGO_REF:0000107
Zmynd8Squirrelpositive regulation of dendritic spine development  ISOZmynd8 (Rattus norvegicus)9068941 RGDPMID:24117785 and REF_RGD_ID:8554267
Zmynd8Squirrelpositive regulation of dendritic spine maintenance  ISOZmynd8 (Rattus norvegicus)9068941 RGDPMID:24117785 and REF_RGD_ID:8554267
Zmynd8Squirrelpositive regulation of filopodium assembly  ISOZmynd8 (Rattus norvegicus)9068941 RGDPMID:24117785 and REF_RGD_ID:8554267
Zmynd8Squirrelpositive regulation of transcription elongation by RNA polymerase II involved_inIEAUniProtKB:Q9ULU4 and ensembl:ENSP00000420095150520179 EnsemblGO_REF:0000107
Zmynd8Squirrelprotein localization to chromatin involved_inIEAUniProtKB:Q9ULU4 and ensembl:ENSP00000420095150520179 EnsemblGO_REF:0000107
Zmynd8Squirrelregulation of DNA-templated transcription involved_inIEAInterPro:IPR037967150520179 InterProGO_REF:0000002
Zmynd8Squirrelregulation of postsynaptic density protein 95 clustering  ISOZmynd8 (Rattus norvegicus)9068941 RGDPMID:24117785 and REF_RGD_ID:8554267
1 to 13 of 13 rows

Cellular Component
1 to 10 of 10 rows

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Zmynd8Squirrelchromatin located_inIEAUniProtKB:Q9ULU4 and ensembl:ENSP00000420095150520179 EnsemblGO_REF:0000107
Zmynd8Squirrelcytoplasm located_inIEAPANTHER:PTN000646290 and PANTHER:PTN000646300150520179 TreeGrafterGO_REF:0000118
Zmynd8Squirrelcytoplasm located_inIEAUniProtKB:Q9ULU4 and ensembl:ENSP00000420095150520179 EnsemblGO_REF:0000107
Zmynd8Squirreldendritic shaft  ISOZmynd8 (Rattus norvegicus)9068941 RGDPMID:24117785 and REF_RGD_ID:8554267
Zmynd8Squirreldendritic spine  ISOZmynd8 (Rattus norvegicus)9068941 RGDPMID:24117785 and REF_RGD_ID:8554267
Zmynd8Squirrelnucleolus located_inIEAUniProtKB:Q9ULU4 and ensembl:ENSP00000420095150520179 EnsemblGO_REF:0000107
Zmynd8Squirrelnucleoplasm located_inIEAUniProtKB:Q9ULU4 and ensembl:ENSP00000420095150520179 EnsemblGO_REF:0000107
Zmynd8Squirrelnucleus located_inIEAUniProtKB:Q9ULU4 and ensembl:ENSP00000420095150520179 EnsemblGO_REF:0000107
Zmynd8Squirrelnucleus located_inIEAPANTHER:PTN000646290 and PANTHER:PTN000646300150520179 TreeGrafterGO_REF:0000118
Zmynd8Squirrelsite of DNA damage located_inIEAUniProtKB:Q9ULU4 and ensembl:ENSP00000420095150520179 EnsemblGO_REF:0000107
1 to 10 of 10 rows

Molecular Function
1 to 20 of 20 rows

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Zmynd8Squirrelhistone H3K14ac reader activity enablesISOZMYND8 (Homo sapiens)9068941 PMID:27477906UniProtPMID:27477906
Zmynd8Squirrelhistone H3K4me1 reader activity enablesISOZMYND8 (Homo sapiens)9068941 PMID:27477906GO_CentralPMID:27477906
Zmynd8Squirrellysine-acetylated histone binding enablesIEAUniProtKB:Q9ULU4 and ensembl:ENSP00000420095150520179 EnsemblGO_REF:0000107
Zmynd8Squirrelmetal ion binding enablesIEAUniProtKB-KW:KW-0479150520179 UniProtGO_REF:0000043
Zmynd8Squirrelmethylated histone binding enablesIEAUniProtKB:Q9ULU4 and ensembl:ENSP00000420095150520179 EnsemblGO_REF:0000107
Zmynd8Squirrelprotein binding enablesISOUniProtKB:Q136279068941 PMID:36950384IntActPMID:36950384
Zmynd8Squirrelprotein binding  ISODbn1 (Rattus norvegicus)9068941protein N-terminus bindingRGDPMID:24117785 and REF_RGD_ID:8554267
Zmynd8Squirrelprotein binding enablesISOUniProtKB:Q9Y6139068941 PMID:15095401BHF-UCLPMID:15095401
Zmynd8Squirrelprotein binding enablesISOUniProtKB:Q166439068941 PMID:28966017UniProtPMID:28966017
Zmynd8Squirrelprotein binding enablesISOUniProtKB:P411829068941 PMID:16147992IntActPMID:16147992
Zmynd8Squirrelprotein binding enablesISOUniProtKB:Q86YP49068941 PMID:27732854UniProtPMID:27732854
Zmynd8Squirrelprotein binding enablesISOUniProtKB:O60563 and UniProtKB:Q148399068941 PMID:30134174UniProtPMID:30134174
Zmynd8Squirrelprotein binding enablesISOUniProtKB:Q072669068941PMID:24117785IntActPMID:24117785 and REF_RGD_ID:8554267
Zmynd8Squirrelprotein binding enablesISOUniProtKB:Q16643 and UniProtKB:Q86YP49068941 PMID:35916866UniProtPMID:35916866
Zmynd8Squirrelprotein binding enablesISOUniProtKB:Q6FHY59068941 PMID:32296183IntActPMID:32296183
Zmynd8Squirrelprotein domain specific binding enablesIEAUniProtKB:Q9ULU4 and ensembl:ENSP00000420095150520179 EnsemblGO_REF:0000107
Zmynd8Squirreltranscription corepressor activity enablesIEAPANTHER:PTN000646290 and PANTHER:PTN000646300150520179 TreeGrafterGO_REF:0000118
Zmynd8Squirreltranscription corepressor activity enablesIEAUniProtKB:Q9ULU4 and ensembl:ENSP00000420095150520179 EnsemblGO_REF:0000107
Zmynd8Squirrelzinc ion binding enablesIEAUniProtKB-KW:KW-0863150520179 UniProtGO_REF:0000043
Zmynd8Squirrelzinc ion binding enablesIEAUniProtKB:Q9ULU4 and ensembl:ENSP00000420095150520179 EnsemblGO_REF:0000107
1 to 20 of 20 rows

PMID:22301074  



Zmynd8
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024408640190,662,525 - 190,760,665 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365146,116,676 - 6,212,996 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365146,116,789 - 6,214,383 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ZMYND8
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382047,209,214 - 47,356,699 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2047,209,214 - 47,356,889 (-)EnsemblGRCh38hg38GRCh38
GRCh372045,837,859 - 45,985,443 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 362045,271,788 - 45,418,881 (-)NCBINCBI36Build 36hg18NCBI36
Build 342045,271,787 - 45,418,881NCBI
Celera2042,552,068 - 42,699,142 (-)NCBICelera
Cytogenetic Map20q13.12NCBI
HuRef2042,581,845 - 42,728,430 (-)NCBIHuRef
CHM1_12045,741,275 - 45,888,362 (-)NCBICHM1_1
T2T-CHM13v2.02048,947,314 - 49,094,980 (-)NCBIT2T-CHM13v2.0
Zmynd8
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm392165,626,072 - 165,740,896 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl2165,626,072 - 165,740,936 (-)EnsemblGRCm39 Ensembl
GRCm382165,784,152 - 165,898,981 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl2165,784,152 - 165,899,016 (-)EnsemblGRCm38mm10GRCm38
MGSCv372165,609,654 - 165,710,188 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv362165,476,506 - 165,588,155 (-)NCBIMGSCv36mm8
Celera2171,721,138 - 171,822,027 (-)NCBICelera
Cytogenetic Map2H3NCBI
cM Map285.98NCBI
Zmynd8
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr83174,948,162 - 175,061,382 (-)NCBIGRCr8
mRatBN7.23154,528,917 - 154,629,532 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl3154,529,043 - 154,628,463 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx3158,334,100 - 158,431,277 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.03166,833,091 - 166,930,269 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.03164,574,727 - 164,671,904 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.03162,480,766 - 162,594,145 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl3162,480,804 - 162,581,610 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.03168,658,022 - 168,771,422 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.43156,860,459 - 156,957,748 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.13156,766,803 - 156,865,056 (-)NCBI
Celera3153,120,868 - 153,217,849 (-)NCBICelera
Cytogenetic Map3q42NCBI
Zmynd8
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495544510,229,902 - 10,363,350 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495544510,226,031 - 10,361,371 (+)NCBIChiLan1.0ChiLan1.0
ZMYND8
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22152,943,925 - 53,104,459 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12052,937,030 - 53,097,569 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02043,540,819 - 43,701,322 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12044,624,487 - 44,784,920 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2044,624,487 - 44,772,032 (-)Ensemblpanpan1.1panPan2
ZMYND8
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12434,322,364 - 34,466,044 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2434,321,570 - 34,485,544 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2433,781,364 - 33,924,600 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02435,030,998 - 35,174,588 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2435,032,085 - 35,157,509 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12434,286,297 - 34,429,942 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02434,404,299 - 34,548,003 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02434,944,918 - 35,088,181 (-)NCBIUU_Cfam_GSD_1.0
ZMYND8
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1749,258,542 - 49,390,399 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11749,258,543 - 49,390,418 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21755,169,682 - 55,300,653 (+)NCBISscrofa10.2Sscrofa10.2susScr3
ZMYND8
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1216,547,144 - 16,696,729 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl216,622,702 - 16,696,878 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605065,181,903 - 65,331,185 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Zmynd8
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247907,493,066 - 7,611,485 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247907,473,739 - 7,611,612 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

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RefSeq Transcripts XM_021726310 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_040275444 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide JAESOR010003700 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSSTOT00000006836   ⟹   ENSSTOP00000006109
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
SpeTri2.0 EnsemblNW_0049365146,125,626 - 6,212,996 (+)Ensembl
Ensembl Acc Id: ENSSTOT00000037157   ⟹   ENSSTOP00000028145
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
SpeTri2.0 EnsemblNW_0049365146,116,896 - 6,212,857 (+)Ensembl
Ensembl Acc Id: ENSSTOT00000037865   ⟹   ENSSTOP00000030159
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
SpeTri2.0 EnsemblNW_0049365146,116,896 - 6,212,996 (+)Ensembl
Ensembl Acc Id: ENSSTOT00000039645   ⟹   ENSSTOP00000029721
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
SpeTri2.0 EnsemblNW_0049365146,145,919 - 6,212,996 (+)Ensembl
Ensembl Acc Id: ENSSTOT00000041300   ⟹   ENSSTOP00000027502
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
SpeTri2.0 EnsemblNW_0049365146,116,676 - 6,162,007 (+)Ensembl
RefSeq Acc Id: XM_040275444   ⟹   XP_040131378
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_024408640190,662,525 - 190,760,665 (+)NCBI
Protein RefSeqs XP_040131378 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSSTOP00000006109.3
  ENSSTOP00000027502.1
  ENSSTOP00000028145.1
  ENSSTOP00000029721.1
  ENSSTOP00000030159.1
GenBank Protein KAG3263487 (Get FASTA)   NCBI Sequence Viewer  
  KAG3263488 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: XP_040131378   ⟸   XM_040275444
- UniProtKB: I3M8M0 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSSTOP00000029721   ⟸   ENSSTOT00000039645
Ensembl Acc Id: ENSSTOP00000027502   ⟸   ENSSTOT00000041300
Ensembl Acc Id: ENSSTOP00000030159   ⟸   ENSSTOT00000037865
Ensembl Acc Id: ENSSTOP00000028145   ⟸   ENSSTOT00000037157
Bromo   MYND-type   PHD-type   PWWP



1 to 40 of 48 rows
Database
Acc Id
Source(s)
Ensembl Genes ENSSTOG00000006811 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSSTOT00000006836.3 UniProtKB/TrEMBL
  ENSSTOT00000037157.1 UniProtKB/TrEMBL
  ENSSTOT00000037865.1 UniProtKB/TrEMBL
  ENSSTOT00000039645.1 UniProtKB/TrEMBL
  ENSSTOT00000041300.1 UniProtKB/TrEMBL
Gene3D-CATH 1.20.920.10 UniProtKB/TrEMBL
  2.30.30.140 UniProtKB/TrEMBL
  3.30.40.10 UniProtKB/TrEMBL
  6.10.140.2220 UniProtKB/TrEMBL
InterPro Bromodomain UniProtKB/TrEMBL
  Bromodomain-like_sf UniProtKB/TrEMBL
  PRKCBP1_PHD UniProtKB/TrEMBL
  PWWP_dom UniProtKB/TrEMBL
  RACK7_Bromo_dom UniProtKB/TrEMBL
  Zinc_finger_PHD-type_CS UniProtKB/TrEMBL
  ZMYND8 UniProtKB/TrEMBL
  Znf_FYVE_PHD UniProtKB/TrEMBL
  Znf_MYND UniProtKB/TrEMBL
  Znf_PHD UniProtKB/TrEMBL
  Znf_PHD-finger UniProtKB/TrEMBL
  Znf_RING/FYVE/PHD UniProtKB/TrEMBL
NCBI Gene Zmynd8 ENTREZGENE
PANTHER PROTEIN KINASE C-BINDING PROTEIN 1 UniProtKB/TrEMBL
  PROTEIN KINASE C-BINDING PROTEIN 1 UniProtKB/TrEMBL
Pfam Bromodomain UniProtKB/TrEMBL
  DUF3544 UniProtKB/TrEMBL
  PHD UniProtKB/TrEMBL
  PWWP UniProtKB/TrEMBL
PRINTS BROMODOMAIN UniProtKB/TrEMBL
PROSITE BROMODOMAIN_2 UniProtKB/TrEMBL
  PWWP UniProtKB/TrEMBL
  ZF_MYND_1 UniProtKB/TrEMBL
  ZF_MYND_2 UniProtKB/TrEMBL
  ZF_PHD_1 UniProtKB/TrEMBL
  ZF_PHD_2 UniProtKB/TrEMBL
SMART BROMO UniProtKB/TrEMBL
  PHD UniProtKB/TrEMBL
  PWWP UniProtKB/TrEMBL
Superfamily-SCOP HIT/MYND zinc finger-like UniProtKB/TrEMBL
1 to 40 of 48 rows