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Gene: Adam8 (ADAM metallopeptidase domain 8) Ictidomys tridecemlineatus

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Symbol:

Adam8

Name:

ADAM metallopeptidase domain 8

RGD ID:

12508840

Description:

ENCODES a protein that exhibits calcium ion binding (inferred); cell adhesion molecule binding (inferred); immunoglobulin receptor binding (inferred); INVOLVED IN angiogenesis (inferred); canonical NF-kappaB signal transduction (inferred); cell morphogenesis (inferred); ASSOCIATED WITH asthma (ortholog); Chemical and Drug Induced Liver Injury (ortholog); distal 10q deletion syndrome (ortholog); FOUND IN alpha9-beta1 integrin-ADAM8 complex (inferred); cell surface (inferred); cytoplasm (inferred)

Type:

protein-coding

RefSeq Status:

MODEL

Previously known as:

disintegrin and metalloproteinase domain-containing protein 8

RGD Orthologs

Alliance Orthologs

More Info

more info ...

Latest Assembly:

SpeTri2.0 - Squirrel SpeTri2.0 Assembly

Position:

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024407213	6,156,736 - 6,171,452 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936486	19,391,324 - 19,402,332 (-)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936486	19,389,925 - 19,403,577 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Only show annotations with direct experimental evidence (0 objects hidden)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
Adam8	Squirrel	asthma		ISO	RGD:1320020	9068941	mRNA:increased expression:respiratory tract	RGD	PMID:19373511\|REF_RGD_ID:5128878
Adam8	Squirrel	asthma	severity	ISO	RGD:1343050	9068941	mRNA:increased expression:bronchus	RGD	PMID:17339047\|REF_RGD_ID:4145380
Adam8	Squirrel	asthma		ISO	RGD:1320020	9068941		RGD	PMID:20194813\|REF_RGD_ID:5128872
Adam8	Squirrel	Experimental Autoimmune Encephalomyelitis		ISO	RGD:1320020	9068941		RGD	PMID:9670863\|REF_RGD_ID:2325244
Adam8	Squirrel	Experimental Autoimmune Neuritis		ISO	RGD:1320020	9068941		RGD	PMID:9670863\|REF_RGD_ID:2325244
Adam8	Squirrel	pancreatic ductal carcinoma	disease_progression	ISO	RGD:1343050	9068941	mRNA:increased expression:pancreas	RGD	PMID:17979891\|REF_RGD_ID:2325243
Adam8	Squirrel	pulmonary eosinophilia		ISO	RGD:1343050	9068941	protein:increased expression:serum	RGD	PMID:19625177\|REF_RGD_ID:5128874

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
Adam8	Squirrel	distal 10q deletion syndrome		ISO	RGD:1343050	8554872	ClinVar Annotator: match by term: Distal 10q deletion syndrome	ClinVar	PMID:31690835

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
Adam8	Squirrel	Chemical and Drug Induced Liver Injury		ISO	RGD:1343050	9068941	CTD Direct Evidence: marker/mechanism	CTD	PMID:24646716

Biological Process

Only show annotations with direct experimental evidence (0 objects hidden)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
Adam8	Squirrel	angiogenesis	involved_in	IEA	UniProtKB:Q05910\|ensembl:ENSMUSP00000101684	150520179		Ensembl	GO_REF:0000107
Adam8	Squirrel	canonical NF-kappaB signal transduction	involved_in	IEA	UniProtKB:Q05910\|ensembl:ENSMUSP00000101684	150520179		Ensembl	GO_REF:0000107
Adam8	Squirrel	cell morphogenesis	involved_in	IEA	UniProtKB:Q05910\|ensembl:ENSMUSP00000101684	150520179		Ensembl	GO_REF:0000107
Adam8	Squirrel	cell-cell adhesion	acts_upstream_of_or_within	IEA	UniProtKB:Q05910\|ensembl:ENSMUSP00000101684	150520179		Ensembl	GO_REF:0000107
Adam8	Squirrel	cellular response to hypoxia	involved_in	IEA	UniProtKB:P78325\|ensembl:ENSP00000453302	150520179		Ensembl	GO_REF:0000107
Adam8	Squirrel	inflammatory response	involved_in	IEA	UniProtKB:P78325\|ensembl:ENSP00000453302	150520179		Ensembl	GO_REF:0000107
Adam8	Squirrel	inflammatory response	involved_in	IEA	PANTHER:PTN000225440	150520179		TreeGrafter	GO_REF:0000118
Adam8	Squirrel	leukocyte migration involved in inflammatory response	involved_in	IEA	UniProtKB:Q05910\|ensembl:ENSMUSP00000101684	150520179		Ensembl	GO_REF:0000107
Adam8	Squirrel	lymphocyte chemotaxis	involved_in	IEA	UniProtKB:Q05910\|ensembl:ENSMUSP00000101684	150520179		Ensembl	GO_REF:0000107
Adam8	Squirrel	negative regulation of neuron apoptotic process	involved_in	IEA	UniProtKB:Q05910\|ensembl:ENSMUSP00000101684	150520179		Ensembl	GO_REF:0000107
Adam8	Squirrel	positive regulation of acute inflammatory response	involved_in	IEA	UniProtKB:Q05910\|ensembl:ENSMUSP00000101684	150520179		Ensembl	GO_REF:0000107
Adam8	Squirrel	positive regulation of bone resorption	involved_in	IEA	UniProtKB:Q05910\|ensembl:ENSMUSP00000101684	150520179		Ensembl	GO_REF:0000107
Adam8	Squirrel	positive regulation of cell adhesion	involved_in	IEA	UniProtKB:Q05910\|ensembl:ENSMUSP00000101684	150520179		Ensembl	GO_REF:0000107
Adam8	Squirrel	positive regulation of cellular extravasation	involved_in	IEA	UniProtKB:Q05910\|ensembl:ENSMUSP00000101684	150520179		Ensembl	GO_REF:0000107
Adam8	Squirrel	positive regulation of cellular extravasation	involved_in	IEA	PANTHER:PTN000225440	150520179		TreeGrafter	GO_REF:0000118
Adam8	Squirrel	positive regulation of eosinophil migration	involved_in	IEA	UniProtKB:Q05910\|ensembl:ENSMUSP00000101684	150520179		Ensembl	GO_REF:0000107
Adam8	Squirrel	positive regulation of epithelial to mesenchymal transition	involved_in	IEA	UniProtKB:Q05910\|ensembl:ENSMUSP00000101684	150520179		Ensembl	GO_REF:0000107
Adam8	Squirrel	positive regulation of fibronectin-dependent thymocyte migration	involved_in	IEA	UniProtKB:Q05910\|ensembl:ENSMUSP00000101684	150520179		Ensembl	GO_REF:0000107
Adam8	Squirrel	positive regulation of inflammatory response	involved_in	IEA	UniProtKB:Q05910\|ensembl:ENSMUSP00000101684	150520179		Ensembl	GO_REF:0000107
Adam8	Squirrel	positive regulation of innate immune response	involved_in	IEA	UniProtKB:Q05910\|ensembl:ENSMUSP00000101684	150520179		Ensembl	GO_REF:0000107
Adam8	Squirrel	positive regulation of MAPK cascade	involved_in	IEA	UniProtKB:Q05910\|ensembl:ENSMUSP00000101684	150520179		Ensembl	GO_REF:0000107
Adam8	Squirrel	positive regulation of membrane protein ectodomain proteolysis	involved_in	IEA	UniProtKB:P78325\|UniProtKB:Q05910\|ensembl:ENSMUSP00000101684\|ensembl:ENSP00000453302	150520179		Ensembl	GO_REF:0000107
Adam8	Squirrel	positive regulation of membrane protein ectodomain proteolysis	involved_in	IEA	PANTHER:PTN000225440	150520179		TreeGrafter	GO_REF:0000118
Adam8	Squirrel	positive regulation of neutrophil extravasation	involved_in	IEA	UniProtKB:P78325\|ensembl:ENSP00000453302	150520179		Ensembl	GO_REF:0000107
Adam8	Squirrel	positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction	involved_in	IEA	UniProtKB:Q05910\|ensembl:ENSMUSP00000101684	150520179		Ensembl	GO_REF:0000107
Adam8	Squirrel	positive regulation of T cell differentiation in thymus	involved_in	IEA	UniProtKB:Q05910\|ensembl:ENSMUSP00000101684	150520179		Ensembl	GO_REF:0000107
Adam8	Squirrel	positive regulation of T cell migration	involved_in	IEA	UniProtKB:Q05910\|ensembl:ENSMUSP00000101684	150520179		Ensembl	GO_REF:0000107
Adam8	Squirrel	positive regulation of thymocyte apoptotic process	involved_in	IEA	UniProtKB:Q05910\|ensembl:ENSMUSP00000101684	150520179		Ensembl	GO_REF:0000107
Adam8	Squirrel	positive regulation of tumor necrosis factor (ligand) superfamily member 11 production	involved_in	IEA	UniProtKB:Q05910\|ensembl:ENSMUSP00000101684	150520179		Ensembl	GO_REF:0000107
Adam8	Squirrel	proteolysis	involved_in	IEA	InterPro:IPR001590	150520179		InterPro	GO_REF:0000002
Adam8	Squirrel	regulation of cell-cell adhesion	involved_in	IEA	UniProtKB:P78325\|ensembl:ENSP00000453302	150520179		Ensembl	GO_REF:0000107
Adam8	Squirrel	regulation of cell-cell adhesion	involved_in	IEA	PANTHER:PTN000225440	150520179		TreeGrafter	GO_REF:0000118
Adam8	Squirrel	signal release	involved_in	IEA	UniProtKB:P78325\|ensembl:ENSP00000453302	150520179		Ensembl	GO_REF:0000107

Cellular Component

Only show annotations with direct experimental evidence (0 objects hidden)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
Adam8	Squirrel	alpha9-beta1 integrin-ADAM8 complex	part_of	IEA	UniProtKB:Q05910\|ensembl:ENSMUSP00000101684	150520179		Ensembl	GO_REF:0000107
Adam8	Squirrel	cell surface	located_in	IEA	UniProtKB:P78325\|ensembl:ENSP00000453302	150520179		Ensembl	GO_REF:0000107
Adam8	Squirrel	cytoplasm	located_in	IEA	UniProtKB:P78325\|ensembl:ENSP00000453302	150520179		Ensembl	GO_REF:0000107
Adam8	Squirrel	dense core granule membrane	located_in	IEA	UniProtKB:P78325\|ensembl:ENSP00000453302	150520179		Ensembl	GO_REF:0000107
Adam8	Squirrel	membrane	located_in	IEA	UniProtKB-KW:KW-0472	150520179		UniProt	GO_REF:0000043
Adam8	Squirrel	membrane	located_in	IEA	UniProtKB-SubCell:SL-0162	150520179		UniProt	GO_REF:0000044
Adam8	Squirrel	phagolysosome	located_in	IEA	UniProtKB:P78325\|ensembl:ENSP00000453302	150520179		Ensembl	GO_REF:0000107
Adam8	Squirrel	plasma membrane	located_in	IEA	UniProtKB:P78325\|UniProtKB:Q05910\|ensembl:ENSMUSP00000101684\|ensembl:ENSP00000453302	150520179		Ensembl	GO_REF:0000107
Adam8	Squirrel	podosome	located_in	IEA	UniProtKB:P78325\|ensembl:ENSP00000453302	150520179		Ensembl	GO_REF:0000107
Adam8	Squirrel	specific granule	located_in	IEA	UniProtKB:P78325\|ensembl:ENSP00000453302	150520179		Ensembl	GO_REF:0000107
Adam8	Squirrel	tertiary granule	located_in	IEA	UniProtKB:P78325\|ensembl:ENSP00000453302	150520179		Ensembl	GO_REF:0000107

Molecular Function

Only show annotations with direct experimental evidence (0 objects hidden)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
Adam8	Squirrel	calcium ion binding	enables	IEA	UniProtKB:Q05910\|ensembl:ENSMUSP00000101684	150520179		Ensembl	GO_REF:0000107
Adam8	Squirrel	cell adhesion molecule binding	enables	IEA	PANTHER:PTN000225440	150520179		TreeGrafter	GO_REF:0000118
Adam8	Squirrel	cell adhesion molecule binding	enables	IEA	UniProtKB:Q05910\|ensembl:ENSMUSP00000101684	150520179		Ensembl	GO_REF:0000107
Adam8	Squirrel	immunoglobulin receptor binding	enables	IEA	UniProtKB:P78325\|ensembl:ENSP00000453302	150520179		Ensembl	GO_REF:0000107
Adam8	Squirrel	metal ion binding	enables	IEA	UniProtKB-KW:KW-0479	150520179		UniProt	GO_REF:0000043
Adam8	Squirrel	metalloendopeptidase activity	enables	IEA	InterPro:IPR001590	150520179		InterPro	GO_REF:0000002
Adam8	Squirrel	metallopeptidase activity	enables	IEA	UniProtKB:P78325\|UniProtKB:Q05910\|ensembl:ENSMUSP00000101684\|ensembl:ENSP00000453302	150520179		Ensembl	GO_REF:0000107
Adam8	Squirrel	metallopeptidase activity	enables	IEA	InterPro:IPR024079	150520179		InterPro	GO_REF:0000002
Adam8	Squirrel	protein binding	enables	ISO	UniProtKB:O95633	9068941	PMID:15574124	UniProt	PMID:15574124
Adam8	Squirrel	protein binding	enables	ISO	UniProtKB:P70232	9068941	PMID:14761956	BHF-UCL	PMID:14761956
Adam8	Squirrel	protein binding	enables	ISO	UniProtKB:P04370	9068941	PMID:12372841	BHF-UCL	PMID:12372841
Adam8	Squirrel	protein binding	enables	ISO	UniProtKB:P06804	9068941	PMID:12135759	BHF-UCL	PMID:12135759
Adam8	Squirrel	protein binding	enables	ISO	UniProtKB:P14598\|UniProtKB:P42680\|UniProtKB:Q15642\|UniProtKB:Q5T0N5	9068941	PMID:25825872	IntAct	PMID:25825872
Adam8	Squirrel	protein binding	enables	ISO	UniProtKB:P14151	9068941	PMID:17548643	BHF-UCL	PMID:17548643
Adam8	Squirrel	tumor necrosis factor receptor superfamily binding	enables	IEA	UniProtKB:P78325\|ensembl:ENSP00000453302	150520179		Ensembl	GO_REF:0000107
Adam8	Squirrel	zinc ion binding	enables	IEA	UniProtKB:Q05910\|ensembl:ENSMUSP00000101684	150520179		Ensembl	GO_REF:0000107

PMID:22301074	PMID:30032202

Adam8
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024407213	6,156,736 - 6,171,452 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936486	19,391,324 - 19,402,332 (-)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936486	19,389,925 - 19,403,577 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

ADAM8
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	10	133,262,423 - 133,276,868 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	10	133,262,420 - 133,276,868 (-)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	10	135,075,927 - 135,090,372 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	10	134,925,911 - 134,940,362 (-)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	10	134,964,788 - 134,979,211	NCBI
Celera	10	128,426,024 - 128,440,474 (+)	NCBI		Celera
Cytogenetic Map	10	q26.3	NCBI
HuRef	10	128,622,621 - 128,637,236 (-)	NCBI		HuRef
CHM1_1	10	135,357,756 - 135,372,278 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	10	134,218,053 - 134,232,489 (-)	NCBI		T2T-CHM13v2.0

Adam8
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	7	139,558,845 - 139,573,016 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	7	139,558,845 - 139,572,475 (-)	Ensembl		GRCm39 Ensembl
GRCm38	7	139,978,932 - 139,995,207 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	7	139,978,932 - 139,992,562 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	7	147,164,840 - 147,178,387 (-)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	7	139,830,261 - 139,843,808 (-)	NCBI		MGSCv36	mm8
Celera	7	139,782,797 - 139,796,305 (-)	NCBI		Celera
Cytogenetic Map	7	F4	NCBI
cM Map	7	84.96	NCBI

Adam8
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	1	204,206,206 - 204,218,988 (-)	NCBI		GRCr8
mRatBN7.2	1	194,776,559 - 194,789,330 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	1	194,770,060 - 194,788,801 (-)	Ensembl		mRatBN7.2 Ensembl
Rnor_6.0	1	212,317,510 - 212,332,895 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	1	212,317,848 - 212,330,349 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	1	219,236,436 - 219,251,059 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	1	199,780,772 - 199,791,855 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
Celera	1	192,454,105 - 192,468,808 (-)	NCBI		Celera
Cytogenetic Map	1	q41	NCBI

Adam8
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955477	10,895,446 - 10,907,215 (-)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955477	10,894,288 - 10,906,961 (-)	NCBI	ChiLan1.0	ChiLan1.0

ADAM8
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	8	145,386,583 - 145,400,948 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	10	145,391,940 - 145,406,305 (-)	NCBI		NHGRI_mPanPan1
PanPan1.1	10	134,171,986 - 134,186,221 (-)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	10	134,172,724 - 134,186,227 (-)	Ensembl	panpan1.1		panPan2

ADAM8
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	28	40,853,665 - 40,865,604 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	28	40,855,509 - 40,863,747 (-)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	28	40,909,672 - 40,921,207 (-)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	28	41,490,792 - 41,502,283 (-)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	28	41,490,100 - 41,500,790 (-)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	28	40,973,551 - 40,985,028 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	28	40,962,945 - 40,974,543 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	28	41,365,582 - 41,377,170 (-)	NCBI		UU_Cfam_GSD_1.0

ADAM8
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	14	141,221,198 - 141,232,306 (-)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	14	141,221,177 - 141,233,728 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	14	153,183,627 - 153,194,348 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

ADAM8
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	26	53,114,184 - 53,129,650 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	26	53,114,924 - 53,126,900 (-)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666054	41,248,757 - 41,264,128 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Adam8
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla 1.0	NW_004624737	13,459,274 - 13,474,686 (+)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.


RefSeq Transcripts	XM_021723415	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_040271851	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	JAESOR010002273	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSSTOT00000000001 ⟹ ENSSTOP00000000001

Type:

CODING

Position:

Squirrel Assembly	Chr	Position (strand)	Source
SpeTri2.0 Ensembl	NW_004936486	19,391,324 - 19,402,332 (-)	Ensembl

Ensembl Acc Id:

ENSSTOT00000041602 ⟹ ENSSTOP00000025939

Type:

CODING

Position:

Squirrel Assembly	Chr	Position (strand)	Source
SpeTri2.0 Ensembl	NW_004936486	19,391,324 - 19,401,578 (-)	Ensembl

RefSeq Acc Id:

XM_040271851 ⟹ XP_040127785

Type:

CODING

Position:

Squirrel Assembly	Chr	Position (strand)	Source
HiC_Itri_2	NW_024407213	6,156,736 - 6,171,452 (+)	NCBI


Protein RefSeqs	XP_040127785	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSSTOP00000000001.3
	ENSSTOP00000025939.1
GenBank Protein	KAG3263822	(Get FASTA)	NCBI Sequence Viewer

RefSeq Acc Id:	XP_040127785 ⟸ XM_040271851
- UniProtKB:	I3LVT4 (UniProtKB/TrEMBL)

Ensembl Acc Id:

ENSSTOP00000000001 ⟸ ENSSTOT00000000001

Ensembl Acc Id:

ENSSTOP00000025939 ⟸ ENSSTOT00000041602

Protein Domains

Disintegrin EGF-like Peptidase M12B

Database	Acc Id	Source(s)
Ensembl Genes	ENSSTOG00000000001	Ensembl, UniProtKB/TrEMBL
Ensembl Transcript	ENSSTOT00000000001.3	UniProtKB/TrEMBL
	ENSSTOT00000041602.1	UniProtKB/TrEMBL
Gene3D-CATH	3.40.390.10	UniProtKB/TrEMBL
	4.10.70.10	UniProtKB/TrEMBL
InterPro	ADAM_Cys-rich	UniProtKB/TrEMBL
	Disintegrin_CS	UniProtKB/TrEMBL
	Disintegrin_dom	UniProtKB/TrEMBL
	Disintegrin_dom_sf	UniProtKB/TrEMBL
	EGF-like_dom	UniProtKB/TrEMBL
	MetalloPept_cat_dom_sf	UniProtKB/TrEMBL
	Peptidase_M12B	UniProtKB/TrEMBL
	Peptidase_M12B_N	UniProtKB/TrEMBL
	Reprolysin_adamalysin	UniProtKB/TrEMBL
NCBI Gene	Adam8	ENTREZGENE
PANTHER	ADAM A DISINTEGRIN AND METALLOPROTEASE DOMAIN	UniProtKB/TrEMBL
	DISINTEGRIN AND METALLOPROTEINASE DOMAIN-CONTAINING PROTEIN 8	UniProtKB/TrEMBL
Pfam	ADAM_CR	UniProtKB/TrEMBL
	Disintegrin	UniProtKB/TrEMBL
	Pep_M12B_propep	UniProtKB/TrEMBL
	Reprolysin	UniProtKB/TrEMBL
PRINTS	DISINTEGRIN	UniProtKB/TrEMBL
PROSITE	ADAM_MEPRO	UniProtKB/TrEMBL
	DISINTEGRIN_1	UniProtKB/TrEMBL
	DISINTEGRIN_2	UniProtKB/TrEMBL
	EGF_2	UniProtKB/TrEMBL
	EGF_3	UniProtKB/TrEMBL
SMART	ACR	UniProtKB/TrEMBL
	DISIN	UniProtKB/TrEMBL
Superfamily-SCOP	Metalloproteases ('zincins'), catalytic domain	UniProtKB/TrEMBL
	SSF57552	UniProtKB/TrEMBL
UniProt	A0A287CXF5_ICTTR	UniProtKB/TrEMBL
	I3LVT4	ENTREZGENE, UniProtKB/TrEMBL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailable


InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailable


Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
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MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable

Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD

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Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD