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Gene: Frzb (frizzled related protein) Ictidomys tridecemlineatus

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Symbol:

Frzb

Name:

frizzled related protein

RGD ID:

12486085

Description:

ENCODES a protein that exhibits Wnt-protein binding (inferred); INVOLVED IN cochlea morphogenesis (ortholog); convergent extension involved in organogenesis (ortholog); epithelial cell development (ortholog); PARTICIPATES IN Wnt signaling, canonical pathway; ASSOCIATED WITH lung adenocarcinoma (ortholog); lung non-small cell carcinoma (ortholog); lung squamous cell carcinoma (ortholog); FOUND IN cytoplasm (inferred); extracellular region (inferred); extracellular space (inferred)

Type:

protein-coding

RefSeq Status:

MODEL

Previously known as:

secreted frizzled-related protein 3

RGD Orthologs

Alliance Orthologs

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	FRZB (frizzled related protein)	NCBI	Ortholog
Mus musculus (house mouse):	Frzb (frizzled-related protein)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Rattus norvegicus (Norway rat):	Frzb (frizzled-related protein)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Frzb (frizzled related protein)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	FRZB (frizzled related protein)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	FRZB (frizzled related protein)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	FRZB (frizzled related protein)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	FRZB (frizzled related protein)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Frzb (frizzled related protein)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline

Latest Assembly:

SpeTri2.0 - Squirrel SpeTri2.0 Assembly

Position:

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024405303	142,886,744 - 142,917,194 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936509	11,440,148 - 11,470,967 (-)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936509	11,440,414 - 11,471,042 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

lung adenocarcinoma (ISO)

lung non-small cell carcinoma (ISO)

lung squamous cell carcinoma (ISO)

osteoarthritis (ISO)

Osteoarthritis, Hip (ISO)

type 2 diabetes mellitus (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

canonical Wnt signaling pathway (IEA)

cell differentiation (IEA)

cochlea morphogenesis (IEA,ISO)

convergent extension involved in organogenesis (IEA,ISO)

developmental process (IEA)

epithelial cell development (IEA,ISO)

hepatocyte differentiation (IEA,ISO)

inner ear morphogenesis (IEA,ISO)

negative regulation of canonical Wnt signaling pathway (IEA,ISO)

negative regulation of cartilage development (IEA,ISO)

negative regulation of cell development (IEA,ISO)

negative regulation of cell growth (IEA)

negative regulation of cell population proliferation (IEA)

negative regulation of hepatocyte differentiation (IEA,ISO)

negative regulation of Wnt signaling pathway (IEA,ISO)

neural crest cell differentiation (IEA)

non-canonical Wnt signaling pathway (IEA)

positive regulation of apoptotic process (IEA,ISO)

positive regulation of fat cell differentiation (IEA,ISO)

somite development (IEA)

Wnt signaling pathway (IEA)

Cellular Component

cytoplasm (IEA)

extracellular region (IEA)

extracellular space (IEA)

Molecular Function

protein binding (ISO)

Wnt-protein binding (IEA)

Molecular Pathway Annotations Click to see Annotation Detail View

Wnt signaling, canonical pathway (ISO)

References

Additional References at PubMed

PMID:30032202

Genomics

Comparative Map Data

Frzb
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024405303	142,886,744 - 142,917,194 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936509	11,440,148 - 11,470,967 (-)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936509	11,440,414 - 11,471,042 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

FRZB
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	2	182,833,275 - 182,866,637 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	2	182,833,275 - 182,866,637 (-)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	2	183,698,002 - 183,731,365 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	2	183,406,982 - 183,439,743 (-)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	2	183,524,242 - 183,557,004	NCBI
Celera	2	177,294,242 - 177,327,734 (-)	NCBI		Celera
Cytogenetic Map	2	q32.1	NCBI
HuRef	2	175,555,371 - 175,588,842 (-)	NCBI		HuRef
CHM1_1	2	183,703,943 - 183,737,410 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	2	183,322,235 - 183,355,596 (-)	NCBI		T2T-CHM13v2.0

Frzb
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	2	80,242,314 - 80,277,740 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	2	80,242,314 - 80,277,969 (-)	Ensembl		GRCm39 Ensembl
GRCm38	2	80,411,970 - 80,447,396 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	2	80,411,970 - 80,447,625 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	2	80,252,127 - 80,287,553 (-)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	2	80,212,809 - 80,248,235 (-)	NCBI		MGSCv36	mm8
Celera	2	82,075,833 - 82,112,383 (-)	NCBI		Celera
Cytogenetic Map	2	C3	NCBI
cM Map	2	48.13	NCBI

Frzb
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	3	85,739,162 - 85,772,168 (-)	NCBI		GRCr8
mRatBN7.2	3	65,332,274 - 65,365,208 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	3	65,332,277 - 65,365,208 (-)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	3	68,678,473 - 68,711,328 (-)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	3	77,262,043 - 77,294,902 (-)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	3	75,024,919 - 75,057,671 (-)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	3	67,635,604 - 67,668,772 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	3	67,635,607 - 67,668,772 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	3	74,196,163 - 74,229,331 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	3	63,350,504 - 63,383,436 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	3	63,246,875 - 63,295,070 (-)	NCBI
Celera	3	64,780,097 - 64,813,027 (-)	NCBI		Celera
Cytogenetic Map	3	q24	NCBI

Frzb
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955403	14,598,765 - 14,631,154 (+)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955403	14,598,765 - 14,627,997 (+)	NCBI	ChiLan1.0	ChiLan1.0

FRZB
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	13	85,492,596 - 85,525,895 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	2B	85,507,574 - 85,540,875 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	2B	70,106,378 - 70,139,333 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	2B	187,915,579 - 187,948,855 (-)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	2B	187,915,579 - 187,948,855 (-)	Ensembl	panpan1.1		panPan2

FRZB
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	36	25,884,557 - 25,907,436 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	36	25,884,557 - 25,907,369 (-)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	36	25,782,614 - 25,812,978 (-)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	36	26,038,918 - 26,069,318 (-)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	36	26,039,164 - 26,076,017 (-)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	36	26,165,036 - 26,195,383 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	36	26,095,997 - 26,126,346 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	36	26,237,636 - 26,268,037 (-)	NCBI		UU_Cfam_GSD_1.0

FRZB
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	15	88,332,860 - 88,377,247 (-)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	15	88,332,856 - 88,377,275 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	15	97,838,143 - 97,881,633 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

FRZB
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	10	68,353,393 - 68,385,135 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	10	68,351,922 - 68,385,110 (-)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666040	131,158,267 - 131,189,920 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Frzb
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624844	4,608,016 - 4,643,141 (-)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624844	4,608,016 - 4,639,582 (-)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Sequence

Nucleotide Sequences


RefSeq Transcripts	XM_005324682	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_040294560	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	JAESOR010000362	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSSTOT00000000685 ⟹ ENSSTOP00000000615

Type:

CODING

Position:

Squirrel Assembly	Chr	Position (strand)	Source
SpeTri2.0 Ensembl	NW_004936509	11,440,148 - 11,470,967 (-)	Ensembl

RefSeq Acc Id:

XM_005324682 ⟹ XP_005324739

Type:

CODING

Position:

Squirrel Assembly	Chr	Position (strand)	Source
HiC_Itri_2	NW_024405303	142,886,744 - 142,917,188 (-)	NCBI
SpeTri2.0	NW_004936509	11,440,414 - 11,471,042 (-)	NCBI

Sequence:

show sequence

CCGTTTGGAGGTGGGAGAGCCAAGAGCTGTAGGTCCCAGCCGCAGACCTCGGGGCTAGGCTCTT
CGCAGCGCACACCGAAAATTGATCTTTCTCAGACTACGGGACGTAGCAAACTCCTACTGTACCC
TCCTCTCCCATTAGTTTCCCCCCTGTTTTCCGCCTTCCTCCCTACCCGGTCCTCCGTCTCTTAT
CCTCGCTTTAGAGAATTGAATGCTTCTTGCTAGCATCTTTTTGGTATCCAGCGGACGCGATACC
CCAAAGCTCCAACTACCTTAGCTGAATGTACTTTTTATTTCTTCCTCTGGTGTTCCTCTCATCT
GATTGATGTGCAAATTCTGGTTCTTCTGCCAGAGGGAGAGGAATAAATAGATGCTGCTGCGCCC
GAAGGCTTAGACGTTTGGAAAGAGCAGCCAAAGCGGCGGGAGCGGAGCTCGGTGAAGCTCGTTG
GACCCCATTGGGGGAATTTGATCCAAGGAAGCTGTGAGATTGCCGGGGGAGGAGAAGCTCCCAG
ATCATTGTGTCCACTTCCAGGCAACAGGAGGAGACGGCGGAGCGGACCTCTCAGCGTCCACGGT
AGTGTTGCTCCCTGTCCCGTTCTGCTGGGATCATGGTCTGCGGCAGCCCAGGAAGGATGCTGCT
GCTGCGAGCTGGGCTGCTCACTCTGGCTGCATTCTGTCTGCTCCAGGTGCCTGGAGCTCGGGCA
GCAGCCTGTGAGCCCGTCCGCATCCCCATGTGCAAGTCCTTGCCCTGGAACATGACCAAGATGC
CCAATCACCTGCACCATAGCACCCAGGCCAATGCCATACTGGCCATCGAGCAATTCGAAGGTCT
GCTGGGCACACATTGCAGCCCAGATCTGCTCTTCTTCCTCTGCGCCATGTACGCACCTATCTGC
ACCATTGACTTCCAGCATGAGCCCATCAAGCCCTGCAAGTCTGTGTGCGAGAGGGCCAGGCAGG
GCTGTGAGCCCATCCTTATCAAGTACCGCCACTCATGGCCGGAGAGCTTGGCCTGCGAGGAATT
ACCAGTGTACGACCGGGGCGTGTGCATCTCTCCGGAGGCCATCGTCACAGCGGATGGAGCAGAT
TTTCCTATGGATTCTAGTAATGGCAACTGTCGAGGTGCAAGCAGCGAACGCTGCAAATGTAAGC
CTATTAGAGCTACACAGAAGACTTATTTCCGGAACAATTACAACTATGTCATCAGGGCTAAGGT
CAAAGAGGTCAAGACCAAGTGCCATGATGTAACTGCAGTGGTGGAGGTGAAGGAGGTTCTCAAG
TCGTCTCTGGTGAACATCCCAAGGGACACCATCAACCTTCACACCAGCTCTGGCTGCCTGTGTC
CTCCACTTACTGTCAATGAGGAGTACATCATCATGGGCTATGAAGATGAGGAACGCTCCAGGTT
ACTTTTGGTGGAAGGCTCTATAGCTGAGAAATGGAAGGATCGACTTGGCAAAAAAGTTAAGCGC
TGGGATATGAAGCTCCGTCATCTTGGACTGAGTAAAAGTGACTCTAGCATTAGTGATTCCACTC
AGAATCAGAAGTCTGGCAGAAACTCTAACCCCCGGCAAGCTCGCAACTAAATCCTGAAATACGA
AGAGTAACATCAGTGGACTTCCTATTGAGACTCGCATTGCTGGACTAGCAAAGGAAAATTGCAC
TATTGCACGTCGCATTCTGTTGTTTACTACAAAAATAATGTGGTAACTGATATTACTTTTATTT
TCTGTTTTTCTCCCCCCACCCACCTTTTTAATGGCCTGGGATTAGATCCTTAAATATATTACAT
TTCCTATTTTAGTAATCACGAAAAAACTTTTTTTAGGGGGGCAATAACAATAAATTAAACATGT
GGATACTAGGGCCCCTTTGCTGGAGTCCCCAGATGTTAATTTCATGTTCTGCACCCAGATTGGA
AAAAACAAAATTGGCTGTAAGGAGAGATTTCTGCTATAAAGCTAGATATGCTTAAAACGTTCTC
TGCTGATCTAATTACAGCCTTATTTTTGTCTGCCATTTGGGCATTTTCCTCATGCTTAGAAAGT
TCTAAAGGTTTATAAAGGTAAAATGGCAGTTTGAAATCAAATGCCACACAAGTACAGGCAAACC
AATCAAGCACCAGGAAGAAGCATTTATGAGGAAATGACACACAGATGAATTATTTCCAAGATTG
GCAGGAAGCAAAAAAAAAAAAAAAAAAAAATAGTGCCAGGAGCCAAGGAAAGAACATTTTGCCT
GATTAAGAAGCACAATTGAAACCAGTAGCCATTTGGGCGTTAACAGTAGCATTCTTCTTTTGGC
AATATATTTGATTTGTTCATGAGTATATTAATCAGCATTAGGGAAGTGAATTGTCACTAGGCAT
CTGCTTGTTATCACCATAGTTTTGTTTAATTTGCTTCCTTCTAAATAAGCCCGTTGGTGGAAGT
GTCCCCACCCTTCCTTCATAATTAATTGGATTTAATGTATTGACCAGGAAAAGAAAGTATGTAC
ACATGTGCACCAGGATATTCCTTTAAAAAGGCATGTTGCTCTATAAAATGGTTTAGTTTACAGG
ACAGTGAAATGTGCAAAAATTTCTTTCTTTTTTTTTTCTTGGTGTGTGTGTATCTGTGTGTATG
TGTGTGTCTATGCACTCACATACCCAAGCTGGTCTAAAGTATAGGCCTGTGTACAGGCCTGACA
TTATCATTTAGATTTGTGCTGTTTAATGCTCAATTGAAAATGTTTAATAAAGGAATTATAGTTG
TCAGGAAAGATTATTCTGACTTTGAAACCAAGTCTACATTCTCATTACCCAAGCTGCAGTGAGA
CCCCCAGGGACCATGGGAAACAAATGATGTTTTTAACTTCCTTCCTCCATCAGGGTTCCTTAGA
GCATGTGCCAATCACTTGAAAGTCTCTTTGCTTGCAGTTTACATGTGTGATATTAGTAGAACCA
AATTTCTAAGCTATGGTGTGCTGAAATAAAACTTATGAAGCAAA

hide sequence

RefSeq Acc Id:

XM_040294560 ⟹ XP_040150494

Type:

CODING

Position:

Squirrel Assembly	Chr	Position (strand)	Source
HiC_Itri_2	NW_024405303	142,886,744 - 142,917,194 (-)	NCBI

Protein Sequences


Protein RefSeqs	XP_005324739	(Get FASTA)	NCBI Sequence Viewer
	XP_040150494	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSSTOP00000000615.3
GenBank Protein	KAG3274826	(Get FASTA)	NCBI Sequence Viewer

RefSeq Acc Id:	XP_005324739 ⟸ XM_005324682
- Peptide Label:	isoform X1
- UniProtKB:	I3LX55 (UniProtKB/TrEMBL)
- Sequence:	show sequence MVCGSPGRMLLLRAGLLTLAAFCLLQVPGARAAACEPVRIPMCKSLPWNMTKMPNHLHHSTQAN AILAIEQFEGLLGTHCSPDLLFFLCAMYAPICTIDFQHEPIKPCKSVCERARQGCEPILIKYRH SWPESLACEELPVYDRGVCISPEAIVTADGADFPMDSSNGNCRGASSERCKCKPIRATQKTYFR NNYNYVIRAKVKEVKTKCHDVTAVVEVKEVLKSSLVNIPRDTINLHTSSGCLCPPLTVNEEYII MGYEDEERSRLLLVEGSIAEKWKDRLGKKVKRWDMKLRHLGLSKSDSSISDSTQNQKSGRNSNP RQARN hide sequence

RefSeq Acc Id:	XP_040150494 ⟸ XM_040294560
- Peptide Label:	isoform X2

Ensembl Acc Id:

ENSSTOP00000000615 ⟸ ENSSTOT00000000685

Protein Domains

FZ NTR

Additional Information

External Database Links

Database	Acc Id	Source(s)
Ensembl Genes	ENSSTOG00000000687	Ensembl, UniProtKB/TrEMBL
Ensembl Transcript	ENSSTOT00000000685.3	UniProtKB/TrEMBL
Gene3D-CATH	1.10.2000.10	UniProtKB/TrEMBL
	2.40.50.120	UniProtKB/TrEMBL
InterPro	Frizzled/SFRP	UniProtKB/TrEMBL
	Frizzled_dom	UniProtKB/TrEMBL
	Frizzled_dom_sf	UniProtKB/TrEMBL
	Netrin_domain	UniProtKB/TrEMBL
	Netrin_module_non-TIMP	UniProtKB/TrEMBL
	NTR_Sfrp3	UniProtKB/TrEMBL
	SFRP3_CRD	UniProtKB/TrEMBL
	TIMP-like_OB-fold	UniProtKB/TrEMBL
NCBI Gene	Frzb	ENTREZGENE
PANTHER	PTHR11309	UniProtKB/TrEMBL
	PTHR11309:SF97	UniProtKB/TrEMBL
Pfam	NTR	UniProtKB/TrEMBL
	PF01392	UniProtKB/TrEMBL
PROSITE	NTR	UniProtKB/TrEMBL
	PS50038	UniProtKB/TrEMBL
SMART	C345C	UniProtKB/TrEMBL
	FRI	UniProtKB/TrEMBL
Superfamily-SCOP	SSF50242	UniProtKB/TrEMBL
	SSF63501	UniProtKB/TrEMBL
UniProt	I3LX55	ENTREZGENE, UniProtKB/TrEMBL

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2017-10-31	Frzb	frizzled related protein		frizzled-related protein	Symbol and/or name change	5135510	APPROVED

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

Imported Disease Annotations - ClinVar

Imported Disease Annotations - OMIM

RGD Manual Annotations

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Imported Disease Annotations - ClinVar

Imported Disease Annotations - OMIM

RGD Manual Annotations