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Gene: NPAS2 (neuronal PAS domain protein 2) Canis lupus familiaris

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Symbol:

NPAS2

Name:

neuronal PAS domain protein 2

RGD ID:

12405303

Description:

ENCODES a protein that exhibits DNA binding (inferred); DNA-binding transcription factor activity (inferred); DNA-binding transcription factor activity, RNA polymerase II-specific (inferred); INVOLVED IN circadian rhythm (ortholog); circadian sleep/wake cycle (ortholog); locomotor rhythm (ortholog); ASSOCIATED WITH autistic disorder (ortholog); Chronobiology Disorders (ortholog); cocaine abuse (ortholog); FOUND IN cytoplasm (inferred); cytosol (inferred); nucleoplasm (inferred)

Type:

protein-coding

RefSeq Status:

MODEL

Previously known as:

neuronal PAS domain-containing protein 2

RGD Orthologs

Alliance Orthologs

More Info

more info ...

Latest Assembly:

CanFam3.1 - Dog CanFam3.1 Assembly

Position:

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	10	41,846,766 - 42,005,058 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	10	41,847,625 - 42,005,469 (-)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	10	41,771,932 - 41,930,470 (-)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	10	42,714,471 - 42,873,104 (-)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	10	42,714,474 - 42,845,094 (-)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	10	42,426,223 - 42,584,492 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	10	42,709,720 - 42,868,321 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	10	42,901,258 - 43,060,042 (-)	NCBI		UU_Cfam_GSD_1.0

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Only show annotations with direct experimental evidence (0 objects hidden)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
NPAS2	Dog	cocaine abuse		ISO	Npas2 (Mus musculus)	9068941	mRNA:decreased expression:hippocampal formation and caudate-putamen (mouse)	RGD	PMID:15994025 and REF_RGD_ID:405866347

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
NPAS2	Dog	spermatogenic failure 3		ISO	NPAS2 (Homo sapiens)	8554872	ClinVar Annotator: match by term: Non-obstructive azoospermia	ClinVar	PMID:25956372

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
NPAS2	Dog	autistic disorder		ISO	NPAS2 (Homo sapiens)	9068941	CTD Direct Evidence: marker/mechanism	CTD	PMID:17264841
NPAS2	Dog	Chronobiology Disorders		ISO	NPAS2 (Homo sapiens)	9068941	CTD Direct Evidence: marker/mechanism	CTD	PMID:31284022
NPAS2	Dog	Experimental Liver Cirrhosis		ISO	NPAS2 (Homo sapiens)	9068941	CTD Direct Evidence: marker/mechanism	CTD	PMID:25380136

Biological Process

Only show annotations with direct experimental evidence (0 objects hidden)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
NPAS2	Dog	circadian regulation of gene expression	involved_in	IEA	InterPro:IPR047230	150520179		InterPro	GO_REF:0000002
NPAS2	Dog	circadian regulation of gene expression	involved_in	IBA	FB:FBgn0023076 more ...	150520179		GO_Central	GO_REF:0000033
NPAS2	Dog	circadian rhythm	involved_in	ISO	Npas2 (Mus musculus)	9068941	PMID:14645221	UniProt	PMID:14645221
NPAS2	Dog	circadian sleep/wake cycle	acts_upstream_of_or_within	ISO	MGI:2180392	9068941	PMID:12843397	MGI	PMID:12843397
NPAS2	Dog	DNA damage response	involved_in	IEA	UniProtKB:Q99743 and ensembl:ENSP00000338283	150520179		Ensembl	GO_REF:0000107
NPAS2	Dog	DNA damage response	involved_in	IEA	UniProtKB-KW:KW-0227	150520179		UniProt	GO_REF:0000043
NPAS2	Dog	locomotor rhythm	acts_upstream_of_or_within	ISO	MGI:2180392	9068941	PMID:12843397	MGI	PMID:12843397
NPAS2	Dog	positive regulation of behavioral fear response	involved_in	ISO	Npas2 (Mus musculus)	9068941	PMID:29163035	UniProt	PMID:29163035
NPAS2	Dog	positive regulation of DNA repair	involved_in	IEA	UniProtKB:Q99743 and ensembl:ENSP00000338283	150520179		Ensembl	GO_REF:0000107
NPAS2	Dog	positive regulation of DNA-templated transcription	involved_in	IEA	UniProtKB:Q99743 and ensembl:ENSP00000338283	150520179		Ensembl	GO_REF:0000107
NPAS2	Dog	regulation of circadian rhythm	involved_in	ISO	Npas2 (Mus musculus)	9068941	PMID:24048828	UniProt	PMID:24048828
NPAS2	Dog	regulation of DNA-templated transcription	involved_in	IEA	InterPro:IPR001067 and InterPro:IPR013767	150520179		InterPro	GO_REF:0000002
NPAS2	Dog	regulation of gene expression	involved_in	IEA	ARBA:ARBA00028334	150520179		UniProt	GO_REF:0000117
NPAS2	Dog	regulation of transcription by RNA polymerase II	involved_in	IEA	GO:0000981	150520179		GOC	GO_REF:0000108
NPAS2	Dog	regulation of transcription by RNA polymerase II	involved_in	IBA	FB:FBgn0023076 more ...	150520179		GO_Central	GO_REF:0000033
NPAS2	Dog	response to redox state	involved_in	IEA	UniProtKB:Q99743 and ensembl:ENSP00000338283	150520179		Ensembl	GO_REF:0000107
NPAS2	Dog	response to xenobiotic stimulus	involved_in	ISO	Npas2 (Mus musculus)	9068941	PMID:29163035	UniProt	PMID:29163035
NPAS2	Dog	rhythmic process	involved_in	IEA	UniProtKB-KW:KW-0090	150520179		UniProt	GO_REF:0000043

Cellular Component

Only show annotations with direct experimental evidence (0 objects hidden)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
NPAS2	Dog	CLOCK-BMAL transcription complex	part_of	IBA	FB:FBgn0023076 more ...	150520179		GO_Central	GO_REF:0000033
NPAS2	Dog	cytoplasm	located_in	IEA	InterPro:IPR001067	150520179		InterPro	GO_REF:0000002
NPAS2	Dog	cytosol	located_in	IEA	UniProtKB:A2I2P5 more ...	150520179		Ensembl	GO_REF:0000107
NPAS2	Dog	nucleoplasm	located_in	IEA	UniProtKB:A2I2P5 more ...	150520179		Ensembl	GO_REF:0000107
NPAS2	Dog	nucleus	located_in	IEA	UniProtKB:Q99743 and ensembl:ENSP00000338283	150520179		Ensembl	GO_REF:0000107
NPAS2	Dog	nucleus	located_in	IEA	InterPro:IPR001067	150520179		InterPro	GO_REF:0000002
NPAS2	Dog	transcription regulator complex	part_of	IEA	InterPro:IPR001067	150520179		InterPro	GO_REF:0000002

Molecular Function

Only show annotations with direct experimental evidence (0 objects hidden)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
NPAS2	Dog	DNA binding	enables	IEA	UniProtKB:Q99743 and ensembl:ENSP00000338283	150520179		Ensembl	GO_REF:0000107
NPAS2	Dog	DNA-binding transcription factor activity	enables	IEA	InterPro:IPR001067	150520179		InterPro	GO_REF:0000002
NPAS2	Dog	DNA-binding transcription factor activity, RNA polymerase II-specific	enables	IEA	InterPro:IPR047230	150520179		InterPro	GO_REF:0000002
NPAS2	Dog	DNA-binding transcription factor activity, RNA polymerase II-specific	enables	IBA	MGI:99698 more ...	150520179		GO_Central	GO_REF:0000033
NPAS2	Dog	Hsp90 protein binding	enables	IEA	UniProtKB:Q99743 and ensembl:ENSP00000338283	150520179		Ensembl	GO_REF:0000107
NPAS2	Dog	protein binding	enables	ISO	UniProtKB:O00327	9068941	PMID:20211142 and PMID:33961781	IntAct	PMID:20211142 and PMID:33961781
NPAS2	Dog	protein binding	enables	ISO	UniProtKB:B2RWS6	9068941	PMID:14645221	UniProt	PMID:14645221
NPAS2	Dog	protein binding	enables	ISO	UniProtKB:Q09472 more ...	9068941	PMID:14645221	UniProt	PMID:14645221
NPAS2	Dog	protein binding	enables	ISO	UniProtKB:O00327-8 and UniProtKB:Q8WYA1-3	9068941	PMID:24722188 and PMID:28514442	IntAct	PMID:24722188 and PMID:28514442
NPAS2	Dog	protein binding	enables	ISO	UniProtKB:P22607 more ...	9068941	PMID:32814053	IntAct	PMID:32814053
NPAS2	Dog	protein binding	enables	ISO	UniProtKB:O00327-8 more ...	9068941	PMID:32296183	IntAct	PMID:32296183
NPAS2	Dog	protein dimerization activity	enables	IEA	InterPro:IPR011598 and InterPro:IPR036638	150520179		InterPro	GO_REF:0000002
NPAS2	Dog	RNA polymerase II cis-regulatory region sequence-specific DNA binding	enables	IBA	MGI:99698 more ...	150520179		GO_Central	GO_REF:0000033
NPAS2	Dog	sequence-specific double-stranded DNA binding	enables	IEA	UniProtKB:Q99743 and ensembl:ENSP00000338283	150520179		Ensembl	GO_REF:0000107

PMID:22301074	PMID:25403511	PMID:30032202

NPAS2
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	10	41,846,766 - 42,005,058 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	10	41,847,625 - 42,005,469 (-)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	10	41,771,932 - 41,930,470 (-)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	10	42,714,471 - 42,873,104 (-)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	10	42,714,474 - 42,845,094 (-)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	10	42,426,223 - 42,584,492 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	10	42,709,720 - 42,868,321 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	10	42,901,258 - 43,060,042 (-)	NCBI		UU_Cfam_GSD_1.0

NPAS2
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	2	100,818,723 - 100,996,829 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	2	100,820,139 - 100,996,829 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	2	101,436,601 - 101,613,291 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	2	100,803,045 - 100,979,719 (+)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	2	100,895,130 - 101,071,805	NCBI
Celera	2	95,641,227 - 95,817,201 (+)	NCBI		Celera
Cytogenetic Map	2	q11.2	NCBI
HuRef	2	95,284,890 - 95,377,330 (+)	NCBI		HuRef
CHM1_1	2	101,440,965 - 101,617,609 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	2	101,278,833 - 101,455,526 (+)	NCBI		T2T-CHM13v2.0

Npas2
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	1	39,233,013 - 39,402,321 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	1	39,232,812 - 39,402,317 (+)	Ensembl		GRCm39 Ensembl
GRCm38	1	39,193,702 - 39,363,240 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	1	39,193,731 - 39,363,236 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	1	39,251,117 - 39,420,085 (+)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	1	39,138,745 - 39,306,732 (+)	NCBI		MGSCv36	mm8
Celera	1	38,989,171 - 39,157,180 (+)	NCBI		Celera
Cytogenetic Map	1	B	NCBI
cM Map	1	17.98	NCBI

Npas2
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	9	48,959,225 - 49,138,036 (+)	NCBI		GRCr8
mRatBN7.2	9	41,463,361 - 41,642,322 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	9	41,463,830 - 41,642,320 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	9	49,959,731 - 50,138,286 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	9	55,082,477 - 55,261,036 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	9	53,364,568 - 53,543,046 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	9	45,901,262 - 46,081,880 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	9	45,901,741 - 46,081,880 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	9	45,590,021 - 45,769,792 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	9	38,255,362 - 38,434,352 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	9	38,256,775 - 38,434,671 (+)	NCBI
Celera	9	39,213,508 - 39,392,002 (+)	NCBI		Celera
Cytogenetic Map	9	q22	NCBI

Npas2
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955470	6,831,992 - 6,905,679 (+)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955470	6,826,541 - 6,906,814 (+)	NCBI	ChiLan1.0	ChiLan1.0

NPAS2
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	12	27,229,065 - 27,405,686 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	2A	27,231,826 - 27,408,436 (-)	NCBI		NHGRI_mPanPan1
PanPan1.1	2A	101,868,932 - 101,972,923 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	2A	101,868,933 - 101,972,866 (+)	Ensembl	panpan1.1		panPan2

Npas2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024406292	86,320,820 - 86,473,227 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936661	95,752 - 210,097 (-)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936661	96,312 - 176,395 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

NPAS2
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	3	53,298,811 - 53,490,574 (-)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	3	53,298,805 - 53,490,375 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	3	55,845,037 - 56,037,026 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

NPAS2
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	14	4,529,048 - 4,705,167 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	14	4,612,225 - 4,705,419 (+)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666041	172,148,777 - 172,325,348 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Npas2
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624749	5,636,782 - 5,790,779 (+)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624749	5,636,878 - 5,790,670 (+)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Variants in NPAS2
2112 total Variants

Assembly: CanFam3.1

Chromosome	Start Pos	End Pos	Reference Nucleotide	Variant Nucleotide	Variant Type	Strain	Variant Page
10	41853201	41853202	G	A	snv	Chinese indigenous dogs (DQ9), Chinese indigenous dogs (DQ4)	View more Information

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

adipose tissue	alimentary part of gastrointestinal system	circulatory system	ectoderm	endocrine system	endoderm	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	mesenchyme	mesoderm	nervous system	reproductive system	respiratory system
6	5	5	23	22	16	6	6	6	6	33	22	12	14	10


RefSeq Transcripts	XM_005626004	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_005626005	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_014117465	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038489004	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038489005	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038550992	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038550993	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038614896	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038614897	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038644579	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038680273	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038680274	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AAEX04000010	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAAHUQ010000099	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAAQRD010000002	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAAUVH010000358	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	REHQ01000010	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSCAFT00000003487 ⟹ ENSCAFP00000003233

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
CanFam3.1 Ensembl	10	41,847,625 - 41,932,242 (-)	Ensembl

Ensembl Acc Id:

ENSCAFT00000047996 ⟹ ENSCAFP00000040536

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
CanFam3.1 Ensembl	10	41,847,625 - 41,932,242 (-)	Ensembl

Ensembl Acc Id:

ENSCAFT00000065193 ⟹ ENSCAFP00000056041

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
CanFam3.1 Ensembl	10	41,847,885 - 42,005,469 (-)	Ensembl

Ensembl Acc Id:

ENSCAFT00000066177 ⟹ ENSCAFP00000061279

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
CanFam3.1 Ensembl	10	41,847,625 - 41,932,242 (-)	Ensembl

Ensembl Acc Id:

ENSCAFT00000091647 ⟹ ENSCAFP00000046684

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
CanFam3.1 Ensembl	10	41,847,625 - 41,932,242 (-)	Ensembl

Ensembl Acc Id:

ENSCAFT00845023455 ⟹ ENSCAFP00845018409

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
ROS_Cfam_1.0 Ensembl	10	42,714,474 - 42,845,094 (-)	Ensembl

Ensembl Acc Id:

ENSCAFT00845023532 ⟹ ENSCAFP00845018472

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
ROS_Cfam_1.0 Ensembl	10	42,714,474 - 42,800,032 (-)	Ensembl

RefSeq Acc Id:

XM_005626004 ⟹ XP_005626061

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
CanFam3.1	10	41,846,766 - 42,005,058 (-)	NCBI
Dog10K_Boxer_Tasha	10	41,771,932 - 41,929,869 (-)	NCBI

Sequence:

show sequence

CCCCTGCACGTTTGGAGAACGCGTAGCCCGGCTCCTCGCTTCGCCTCGCCGCCGCTCCCCAGCTTGGATGCCAGCGCGCTGTTTTGATAGGAGGCGTGCCCCCTCCCCGGGGCCGCCGAGGAGCCCTA
CCTTTGACCTCTCCGTGGAGCTGCGCGGGGTCCTTCAGCAGGGGGAGCGGGGACAGGTGCCAGGGAGCTAAATTAAAAACCCCGCTCCTCTGCCTGCCGCTCCTTGACTGCTCAAGGAAAAACTGCAT
AGAAAATCTAATGGATGAAGATGAGAAAGACAGGGCAAAGAGAGCTTCTCGAAACAAGTCTGAGAAGAAGCGTCGGGACCAGTTCAATGTTCTCATCAAAGAGCTTAGCTCCATGCTCCCTGGCAACA
CTCGGAAAATGGACAAAACCACCGTGCTGGAAAAGGTCATTGGATTTTTGCAGAAACACAATGGTAAAGAAGTCTCAGCGCAAACGGAAATCTGTGATATTCAACAGGACTGGAAGCCTTCATTCCTC
AGTAATGAAGAATTCACCCAGCTGATGTTGGAGGCCCTGGACGGCTTCATCATCGCAGTGACGACCGACGGCAGCATCCTCTATGTTTCTGACAGTATCACGCCTCTCCTTGGGCATTTACCGTCAGA
TGTCATGGATCAGAATTTGTTAAATTTCCTTCCAGAACAAGAACATTCAGAAGTGTATAAAATGCTTTCTTCCCATATGCTTGTGACAGATTCCCCCTCCCCAGAATACTTAAAATCTGACAACGATT
TAGAGTTTTATTGCCATCTTCTCAGAGGCAGCTTGAACCCAAAGGAATTTCCAACTTATGAATACATAAAATTTGTAGGAAATTTTCGCTCTTACAACAATGTGCCTAGCCCCTCTTGTAATGGCTTT
GACAGCACCCTTTCAAGACCCTGCCGGGTGCCGCTAGGAAAGGAGGTCTGCTTCATCGCCACCGTTCGTCTGGCAACGCCACAATTCTTAAAGGAAATGTGCATAGTTGACGAACCCTTAGAGGAATT
CACTTCAAGGCATAGCTTGGAATGGAAATTTTTATTTCTGGATCACAGAGCCCCTCCGATCATAGGGTACCTGCCTTTTGAAGTTTTGGGGACCTCGGGCTATGACTACTACCACATCGATGATCTGG
AGCTCCTGGCCAGGTGCCACCAGCACTTGATGCAGTTTGGTAAAGGGAAGTCCTGTTGCTACCGGTTTCTGACCAAGGGCCAGCAGTGGATCTGGCTGCAGACGCACTACTACATCACTTACCACCAG
TGGAACTCCAAGCCCGAGTTCATCGTGTGCACACACTCGGTTGTCAGTTATGCAGATGTCCGGGTAGAAAGGAGGCAGGAGCTGGCTTTGGAAGACCCGCCCCCTGAGGCTGTCCACGCTTCGGCACT
AAAGGACAAGGGCTCCAGCCTGGACCCTACGCAGCACTTTAATGCACTTGACGCTGGCACCTTGGGCCTTAACACCAATCACTCACCATCGGTGTCCTCCAGAAGCTCCCACAAATCCTCGCACACGG
CCATGTCAGAGCCCGCCTCCACCCCGAGCAAGCTGATGGCAGAGGCCAGCACCACGGCTTTGCCGAGATCGGCTGCGCTGCCCCAAGAGCTCCCCGTGCCAGGGCTCAGCCAGGCAGCCACCATGCCG
GCACCCCTGCCGGCCCCATCATCCTGTAACCTTACACAGCAGCTCCTGCCTCAGACCATCCTGCAGAGCTCCCCTGCCCCCATGACACAGTTCTCAGCACAGTTCAGCATGTTCCAGACCATCAAAGA
CCAGCTGGAGCAGCGGACACGGATCCTGCAAGCCAACATCCGGTGGCAGCAGGAAGAGCTCCACAAGATCCAGGAGCAGCTCTGCTTGGTCCAGGATTCCAACATGCAGATGTTTCTGCAGCAGCCAG
CTGGCTCCCTGAGCTTCAGCAGCGCCCCGCGGCCCGAGGCTCCACAGCAACTCCAGCAGAGGTCGGCCCCCAGCTCCCAGTCCCAGCTCGTGGCCAGCCCTCAACTTCCAGGGCAGATGGCCTCTGCC
CAGGTGGCCAACCAGCACCTGCTCAGAGAATCCAGTGTGATATCAACCCAGGGCCCGCGGCCAATGAGAAGCTCACAGATGATGCAGGGCAGCGGCCACTCGGTGAGCACCCTGGCGCCCCAGTTCAG
CAGCGCCGCGGCCGCGCTCCCGCCGGCTCTGAGCCTGACCACGCTCGCTTCTGCCTCCCAGGACGGCAGCCAGTGCCAGCCCAGCCCAGACTTCAGCCACGATCGGCAGCTCAGGCTGCTGCTGAGCC
AGCCCATCCAGCCCATGATGCCTGGGTCCTGTGACGCGAGGCAGCCCTCAGAGGTCAGCAGGACTGGACGGCAAGTCAAGTATCCACAGAGCCAAGCCGTGTTTCAAAACACAGACATGCGCACCACC
AGCAGCAGCACCTCACCCCCCGTCCTGCTGATGGGACAGGCAGTGCCCCAGCCCAGCTTCCCCGCCTCCCGGCAGTCACCCCTGCAGCCCGCACAGGCCCAGCAGCAGCCACAGCACTTCCTGCAGGT
ACAGGCACCAAGCTCTCTGCACAGTGAGCAGCAGGACTCGCTCCTTCTCTCCACCTACTCGCAGCAGCCAGGGACCCTGGGCTACCCCCCACCCCCGCAGCCCCCACGCCCTCCCCGAAGGGTCAGCG
GCCTCTCCGAGTCCTCGGGCCTCCAGCAGCCACCCCGGTAGTGCCCTGGCGCCTCAGCCCAGGCACAATCAGCTTTAACCAATGGACGGACCATGGGGGTGGCCAGAGGAATCGGGGAGAGGAGTTCA
AACCCTCGGCTTTTGTGCACACTGCATACATTTCAGAACTCCTGGAAGCTAACCGTCTCCAGAGAGCAGTGGCTGGCATGTGGAAAGTGATCAGGATACTGGCAGTGTTTCCCTTGCCTCTGTTTCTC
GGGCACACTCTACAGCCAGACTCGGACAGGAACCGAGGGCCCCACGTAAGTGTCGTTACTCAGTTTACTCAGCAGATGGCACGTCTCGCTGCGTCCCTCCCGAGAGCGCACGGGTCCCTCTAGCCGGC
TGTGGTCTGTCCACACCTGCTAGCTGCTGGCCTTCACTCTCTTGATCCTCTTTCCTTGGCATTCGAGAAGCACTGGGTCAGAGATCTGTTGAAGAGAGAGAATAAAAAGATTATTTTTCATTATTTTT
AAATGGCTGTTTTTGTTTTAATTTGCACAGCTGCACAGAGGAAATAACTTAGGCACTTTCAGGTTTTAAAAATAATAAGGTCTCGTGACTTCACTTGGAGACAGCGGGGAACAAAAAGAGCCCACCAA
TCTGATGGCAGAGCCGGTCAGCAAGAACCAGGCCGCAGACCCCCGCCCTCTGGCCTGAAACCTAATGGAAGGCGGCCCTTCCTGGTGATTAGTGTTTCCCCCAAACATAACACTGGACTGTTCCTGTT
TACTTCGTTGATTGCGACTGCAGAGGCGGCCTCAAAGCAAAGCACAATCACAGCAGCTGATATTCTGGAATTCTGTTGAGACAGAACGGGAGGAACAGGTGTCGCGAGCCAGGCAGGCCCGTTGGAAC
TCCAGGTCCCCAAGGAAACCCCAGCAGGCGCCGGCCCCTGAGTCAGAATGCTGCATCTTTCTACAGATCTTTCATGAGGAGACCGAGGATTGGATTGTCCTTTTCAAAATGCACTTTGCTTTTTTTGT
ATGTTTTGTTATGTTGAGATGTTTCTAAAGAAGAGATTTTATGTAATTAAAAGACGAAGTGTAGTGAATTGTACAGCTGTTGTAATAATGACCTATTTCTATATAAAATAAAATTGTATGGATTATGT
GTAAATTA

hide sequence

RefSeq Acc Id:

XM_038489004 ⟹ XP_038344932

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
UMICH_Zoey_3.1	10	42,426,223 - 42,583,892 (-)	NCBI

RefSeq Acc Id:

XM_038489005 ⟹ XP_038344933

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
UMICH_Zoey_3.1	10	42,426,223 - 42,584,492 (-)	NCBI

RefSeq Acc Id:

XM_038550992 ⟹ XP_038406920

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
UU_Cfam_GSD_1.0	10	42,901,258 - 43,059,437 (-)	NCBI

RefSeq Acc Id:

XM_038550993 ⟹ XP_038406921

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
UU_Cfam_GSD_1.0	10	42,901,258 - 43,060,042 (-)	NCBI

RefSeq Acc Id:

XM_038614896 ⟹ XP_038470824

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
UNSW_CanFamBas_1.0	10	42,709,720 - 42,867,726 (-)	NCBI

RefSeq Acc Id:

XM_038614897 ⟹ XP_038470825

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
UNSW_CanFamBas_1.0	10	42,709,720 - 42,868,321 (-)	NCBI

RefSeq Acc Id:

XM_038644579 ⟹ XP_038500507

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
Dog10K_Boxer_Tasha	10	41,771,932 - 41,930,470 (-)	NCBI

RefSeq Acc Id:

XM_038680273 ⟹ XP_038536201

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
ROS_Cfam_1.0	10	42,714,471 - 42,872,503 (-)	NCBI

RefSeq Acc Id:

XM_038680274 ⟹ XP_038536202

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
ROS_Cfam_1.0	10	42,714,471 - 42,873,104 (-)	NCBI


Protein RefSeqs	XP_005626061	(Get FASTA)	NCBI Sequence Viewer
	XP_038344932	(Get FASTA)	NCBI Sequence Viewer
	XP_038344933	(Get FASTA)	NCBI Sequence Viewer
	XP_038406920	(Get FASTA)	NCBI Sequence Viewer
	XP_038406921	(Get FASTA)	NCBI Sequence Viewer
	XP_038470824	(Get FASTA)	NCBI Sequence Viewer
	XP_038470825	(Get FASTA)	NCBI Sequence Viewer
	XP_038500507	(Get FASTA)	NCBI Sequence Viewer
	XP_038536201	(Get FASTA)	NCBI Sequence Viewer
	XP_038536202	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSCAFP00000003233.5
	ENSCAFP00000040536.2
	ENSCAFP00030033894.1
	ENSCAFP00030033984.1
	ENSCAFP00845018409
	ENSCAFP00845018409.1
	ENSCAFP00845018472.1

RefSeq Acc Id:	XP_005626061 ⟸ XM_005626004
- Peptide Label:	isoform X1
- UniProtKB:	A0A8I3NL16 (UniProtKB/TrEMBL)
- Sequence:	show sequence MDEDEKDRAKRASRNKSEKKRRDQFNVLIKELSSMLPGNTRKMDKTTVLEKVIGFLQKHNGKEVSAQTEICDIQQDWKPSFLSNEEFTQLMLEALDGFIIAVTTDGSILYVSDSITPLLGHLPSDVMD QNLLNFLPEQEHSEVYKMLSSHMLVTDSPSPEYLKSDNDLEFYCHLLRGSLNPKEFPTYEYIKFVGNFRSYNNVPSPSCNGFDSTLSRPCRVPLGKEVCFIATVRLATPQFLKEMCIVDEPLEEFTSR HSLEWKFLFLDHRAPPIIGYLPFEVLGTSGYDYYHIDDLELLARCHQHLMQFGKGKSCCYRFLTKGQQWIWLQTHYYITYHQWNSKPEFIVCTHSVVSYADVRVERRQELALEDPPPEAVHASALKDK GSSLDPTQHFNALDAGTLGLNTNHSPSVSSRSSHKSSHTAMSEPASTPSKLMAEASTTALPRSAALPQELPVPGLSQAATMPAPLPAPSSCNLTQQLLPQTILQSSPAPMTQFSAQFSMFQTIKDQLE QRTRILQANIRWQQEELHKIQEQLCLVQDSNMQMFLQQPAGSLSFSSAPRPEAPQQLQQRSAPSSQSQLVASPQLPGQMASAQVANQHLLRESSVISTQGPRPMRSSQMMQGSGHSVSTLAPQFSSAA AALPPALSLTTLASASQDGSQCQPSPDFSHDRQLRLLLSQPIQPMMPGSCDARQPSEVSRTGRQVKYPQSQAVFQNTDMRTTSSSTSPPVLLMGQAVPQPSFPASRQSPLQPAQAQQQPQHFLQVQAP SSLHSEQQDSLLLSTYSQQPGTLGYPPPPQPPRPPRRVSGLSESSGLQQPPR hide sequence

Ensembl Acc Id:

ENSCAFP00000046684 ⟸ ENSCAFT00000091647

Ensembl Acc Id:

ENSCAFP00000003233 ⟸ ENSCAFT00000003487

Ensembl Acc Id:

ENSCAFP00000040536 ⟸ ENSCAFT00000047996

Ensembl Acc Id:

ENSCAFP00000056041 ⟸ ENSCAFT00000065193

Protein Domains

bHLH PAS

Database	Acc Id	Source(s)
Ensembl Genes	ENSCAFG00000002223	Ensembl, UniProtKB/TrEMBL
	ENSCAFG00030021171	UniProtKB/TrEMBL
	ENSCAFG00845013162	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSCAFT00000003487.6	UniProtKB/TrEMBL
	ENSCAFT00000047996.3	UniProtKB/TrEMBL
	ENSCAFT00030038865.1	UniProtKB/TrEMBL
	ENSCAFT00030038962.1	UniProtKB/TrEMBL
	ENSCAFT00845023455	ENTREZGENE
	ENSCAFT00845023455.1	UniProtKB/TrEMBL
	ENSCAFT00845023532.1	UniProtKB/TrEMBL
Gene3D-CATH	4.10.280.10	UniProtKB/TrEMBL
	PAS domain	UniProtKB/TrEMBL
InterPro	bHLH_dom	UniProtKB/TrEMBL
	CLOCK-like	UniProtKB/TrEMBL
	HLH_DNA-bd_sf	UniProtKB/TrEMBL
	Nuc_translocat	UniProtKB/TrEMBL
	PAC	UniProtKB/TrEMBL
	PAS	UniProtKB/TrEMBL
	PAS-like_dom_sf	UniProtKB/TrEMBL
	PAS_fold	UniProtKB/TrEMBL
NCBI Gene	NPAS2	ENTREZGENE
PANTHER	CIRCADIAN LOCOMOTER OUTPUT CYCLES PROTEIN KAPUT	UniProtKB/TrEMBL
	NEURONAL PAS DOMAIN-CONTAINING PROTEIN 2	UniProtKB/TrEMBL
Pfam	HLH	UniProtKB/TrEMBL
	PAS	UniProtKB/TrEMBL
	PAS_11	UniProtKB/TrEMBL
PRINTS	NCTRNSLOCATR	UniProtKB/TrEMBL
PROSITE	BHLH	UniProtKB/TrEMBL
	PAS	UniProtKB/TrEMBL
SMART	HLH	UniProtKB/TrEMBL
	PAC	UniProtKB/TrEMBL
	PAS	UniProtKB/TrEMBL
Superfamily-SCOP	SSF47459	UniProtKB/TrEMBL
	SSF55785	UniProtKB/TrEMBL
UniProt	A0A8C0P2R7_CANLF	UniProtKB/TrEMBL
	A0A8C0RQ46	ENTREZGENE, UniProtKB/TrEMBL
	A0A8I3NL16	ENTREZGENE, UniProtKB/TrEMBL
	A0A8I3NQ21_CANLF	UniProtKB/TrEMBL
	A0A8P0S8B5	ENTREZGENE
UniProt Secondary	A0A8P0S8B5	UniProtKB/TrEMBL
VGNC ID	VGNC:43909	ENTREZGENE

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailable


InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailable


Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
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MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable

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