Npas2 (neuronal PAS domain protein 2) - Rat Genome Database

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Gene: Npas2 (neuronal PAS domain protein 2) Chinchilla lanigera
Analyze
Symbol: Npas2
Name: neuronal PAS domain protein 2
RGD ID: 9008432
Description: ENCODES a protein that exhibits DNA binding (ortholog); Hsp90 protein binding (ortholog); sequence-specific double-stranded DNA binding (ortholog); INVOLVED IN circadian regulation of gene expression (ortholog); circadian rhythm (ortholog); circadian sleep/wake cycle (ortholog); ASSOCIATED WITH autistic disorder (ortholog); Chronobiology Disorders (ortholog); Experimental Liver Cirrhosis (ortholog); FOUND IN cytosol (ortholog); nucleoplasm (ortholog); nucleus (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: neuronal PAS domain-containing protein 2
RGD Orthologs
Human
Mouse
Rat
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: ChiLan1.0 - Chinchilla ChiLan1.0 Assembly
NCBI Annotation Information: Annotation category: partial on reference assembly
Position:
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554706,831,992 - 6,905,679 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554706,826,541 - 6,906,814 (+)NCBIChiLan1.0ChiLan1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
cytosol  (ISO)
nucleoplasm  (ISO)
nucleus  (ISO)

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Transitive Annotation Pipeline Automated assignment of GO, PW and RDO ISO annotations across species
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Npas2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554706,831,992 - 6,905,679 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554706,826,541 - 6,906,814 (+)NCBIChiLan1.0ChiLan1.0
NPAS2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382100,818,723 - 100,996,829 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2100,820,139 - 100,996,829 (+)EnsemblGRCh38hg38GRCh38
GRCh372101,436,601 - 101,613,291 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 362100,803,045 - 100,979,719 (+)NCBINCBI36Build 36hg18NCBI36
Build 342100,895,130 - 101,071,805NCBI
Celera295,641,227 - 95,817,201 (+)NCBICelera
Cytogenetic Map2q11.2NCBI
HuRef295,284,890 - 95,377,330 (+)NCBIHuRef
CHM1_12101,440,965 - 101,617,609 (+)NCBICHM1_1
T2T-CHM13v2.02101,278,833 - 101,455,526 (+)NCBIT2T-CHM13v2.0
Npas2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39139,233,013 - 39,402,321 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl139,232,812 - 39,402,317 (+)EnsemblGRCm39 Ensembl
GRCm38139,193,702 - 39,363,240 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl139,193,731 - 39,363,236 (+)EnsemblGRCm38mm10GRCm38
MGSCv37139,251,117 - 39,420,085 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36139,138,745 - 39,306,732 (+)NCBIMGSCv36mm8
Celera138,989,171 - 39,157,180 (+)NCBICelera
Cytogenetic Map1BNCBI
cM Map117.98NCBI
Npas2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8948,959,225 - 49,138,036 (+)NCBIGRCr8
mRatBN7.2941,463,361 - 41,642,322 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl941,463,830 - 41,642,320 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx949,959,731 - 50,138,286 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0955,082,477 - 55,261,036 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0953,364,568 - 53,543,046 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0945,901,262 - 46,081,880 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl945,901,741 - 46,081,880 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0945,590,021 - 45,769,792 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4938,255,362 - 38,434,352 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1938,256,775 - 38,434,671 (+)NCBI
Celera939,213,508 - 39,392,002 (+)NCBICelera
Cytogenetic Map9q22NCBI
NPAS2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21227,229,065 - 27,405,686 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12A27,231,826 - 27,408,436 (-)NCBINHGRI_mPanPan1
PanPan1.12A101,868,932 - 101,972,923 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2A101,868,933 - 101,972,866 (+)Ensemblpanpan1.1panPan2
NPAS2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11041,846,766 - 42,005,058 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1041,847,625 - 42,005,469 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1041,771,932 - 41,930,470 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01042,714,471 - 42,873,104 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1042,714,474 - 42,845,094 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11042,426,223 - 42,584,492 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01042,709,720 - 42,868,321 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01042,901,258 - 43,060,042 (-)NCBIUU_Cfam_GSD_1.0
Npas2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440629286,320,820 - 86,473,227 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493666195,752 - 210,097 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493666196,312 - 176,395 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
NPAS2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl353,298,811 - 53,490,574 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1353,298,805 - 53,490,375 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2355,845,037 - 56,037,026 (-)NCBISscrofa10.2Sscrofa10.2susScr3
NPAS2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1144,529,048 - 4,705,167 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl144,612,225 - 4,705,419 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666041172,148,777 - 172,325,348 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Npas2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247495,636,782 - 5,790,779 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247495,636,878 - 5,790,670 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSCLAT00000009051   ⟹   ENSCLAP00000008923
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0 EnsemblNW_0049554706,831,992 - 6,905,679 (+)Ensembl
RefSeq Acc Id: XM_013522756   ⟹   XP_013378210
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_0049554706,826,541 - 6,906,814 (+)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_013378210 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSCLAP00000008923
  ENSCLAP00000008923.1
Reference Protein Sequences
RefSeq Acc Id: XP_013378210   ⟸   XM_013522756
- UniProtKB: A0A8C2V3T2 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSCLAP00000008923   ⟸   ENSCLAT00000009051
Protein Domains
bHLH   PAS


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCLAG00000006228 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCLAT00000009051 ENTREZGENE
  ENSCLAT00000009051.1 UniProtKB/TrEMBL
Gene3D-CATH 4.10.280.10 UniProtKB/TrEMBL
  PAS domain UniProtKB/TrEMBL
InterPro bHLH_dom UniProtKB/TrEMBL
  CLOCK-like UniProtKB/TrEMBL
  HLH_DNA-bd_sf UniProtKB/TrEMBL
  Nuc_translocat UniProtKB/TrEMBL
  PAC UniProtKB/TrEMBL
  PAS UniProtKB/TrEMBL
  PAS-like_dom_sf UniProtKB/TrEMBL
  PAS_fold UniProtKB/TrEMBL
NCBI Gene Npas2 ENTREZGENE
PANTHER CIRCADIAN LOCOMOTER OUTPUT CYCLES PROTEIN KAPUT UniProtKB/TrEMBL
  NEURONAL PAS DOMAIN-CONTAINING PROTEIN 2 UniProtKB/TrEMBL
Pfam HLH UniProtKB/TrEMBL
  PAS UniProtKB/TrEMBL
  PAS_11 UniProtKB/TrEMBL
PRINTS NCTRNSLOCATR UniProtKB/TrEMBL
PROSITE BHLH UniProtKB/TrEMBL
  PAS UniProtKB/TrEMBL
SMART HLH UniProtKB/TrEMBL
  PAC UniProtKB/TrEMBL
  PAS UniProtKB/TrEMBL
Superfamily-SCOP SSF47459 UniProtKB/TrEMBL
  SSF55785 UniProtKB/TrEMBL
UniProt A0A8C2V3T2 ENTREZGENE, UniProtKB/TrEMBL