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Gene: HLX (H2.0 like homeobox) Canis lupus familiaris

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Symbol:

HLX

Name:

H2.0 like homeobox

RGD ID:

12340617

Description:

ENCODES a protein that exhibits DNA binding (inferred); DNA-binding transcription factor activity, RNA polymerase II-specific (inferred); sequence-specific DNA binding (inferred); INVOLVED IN animal organ development (inferred); cell population proliferation (inferred); embryonic digestive tract morphogenesis (inferred); PARTICIPATES IN interleukin-12 signaling pathway; ASSOCIATED WITH gastrointestinal stromal tumor (ortholog); Loeys-Dietz syndrome 4 (ortholog); parathyroid carcinoma (ortholog); FOUND IN nucleus (inferred)

Type:

protein-coding

RefSeq Status:

MODEL

Previously known as:

H2.0 homeobox 1; H2.0-like homeo box 1; H2.0-like homeobox protein

RGD Orthologs

Alliance Orthologs

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	HLX (H2.0 like homeobox)	HGNC	EggNOG, Ensembl, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, OrthoMCL, Panther, Treefam
Mus musculus (house mouse):	Hlx (H2.0-like homeobox)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Rattus norvegicus (Norway rat):	Hlx (H2.0-like homeobox)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Hlx (H2.0 like homeobox)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	HLX (H2.0 like homeobox)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Hlx (H2.0 like homeobox)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	HLX (H2.0 like homeobox)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	HLX (H2.0 like homeobox)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Hlx (H2.0 like homeobox)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline

Latest Assembly:

CanFam3.1 - Dog CanFam3.1 Assembly

Position:

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	38	15,538,744 - 15,543,686 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	38	15,539,029 - 15,542,152 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	38	15,580,303 - 15,585,398 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	38	15,575,409 - 15,580,508 (+)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	38	15,575,655 - 15,580,859 (+)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	38	15,582,466 - 15,587,573 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	38	15,937,032 - 15,942,341 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	38	16,230,020 - 16,235,130 (+)	NCBI		UU_Cfam_GSD_1.0

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
HLX	Dog	gastrointestinal stromal tumor		ISO	HLX (Homo sapiens)	8554872	ClinVar Annotator: match by term: Gastrointestinal stromal tumor	ClinVar	PMID:28492532
HLX	Dog	Loeys-Dietz syndrome 4		ISO	HLX (Homo sapiens)	8554872	ClinVar Annotator: match by term: Loeys-Dietz syndrome 4	ClinVar	PMID:22772368 and PMID:28544325
HLX	Dog	parathyroid carcinoma		ISO	HLX (Homo sapiens)	8554872	ClinVar Annotator: match by term: Parathyroid carcinoma	ClinVar	PMID:28492532
HLX	Dog	Usher syndrome		ISO	HLX (Homo sapiens)	8554872	ClinVar Annotator: match by term: Usher syndrome	ClinVar	PMID:28041643

Biological Process

Only show annotations with direct experimental evidence (0 objects hidden)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
HLX	Dog	animal organ development	acts_upstream_of_or_within	IEA	UniProtKB:Q61670 and ensembl:ENSMUSP00000040505	150520179		Ensembl	GO_REF:0000107
HLX	Dog	cell population proliferation	acts_upstream_of	IEA	UniProtKB:Q61670 and ensembl:ENSMUSP00000040505	150520179		Ensembl	GO_REF:0000107
HLX	Dog	embryonic digestive tract morphogenesis	acts_upstream_of_or_within	IEA	UniProtKB:Q61670 and ensembl:ENSMUSP00000040505	150520179		Ensembl	GO_REF:0000107
HLX	Dog	enteric nervous system development	acts_upstream_of_or_within	IEA	UniProtKB:Q61670 and ensembl:ENSMUSP00000040505	150520179		Ensembl	GO_REF:0000107
HLX	Dog	epithelial cell proliferation	acts_upstream_of	IEA	UniProtKB:Q61670 and ensembl:ENSMUSP00000040505	150520179		Ensembl	GO_REF:0000107
HLX	Dog	liver development	acts_upstream_of_or_within	IEA	UniProtKB:Q61670 and ensembl:ENSMUSP00000040505	150520179		Ensembl	GO_REF:0000107
HLX	Dog	negative regulation of T-helper 2 cell differentiation	acts_upstream_of_or_within	IEA	UniProtKB:Q61670 and ensembl:ENSMUSP00000040505	150520179		Ensembl	GO_REF:0000107
HLX	Dog	organ growth	acts_upstream_of	IEA	UniProtKB:Q61670 and ensembl:ENSMUSP00000040505	150520179		Ensembl	GO_REF:0000107
HLX	Dog	positive regulation of epithelial cell proliferation	acts_upstream_of_or_within	IEA	UniProtKB:Q61670 and ensembl:ENSMUSP00000040505	150520179		Ensembl	GO_REF:0000107
HLX	Dog	positive regulation of organ growth	acts_upstream_of_or_within	IEA	UniProtKB:Q61670 and ensembl:ENSMUSP00000040505	150520179		Ensembl	GO_REF:0000107
HLX	Dog	positive regulation of T-helper 1 cell differentiation	acts_upstream_of_or_within	IEA	UniProtKB:Q61670 and ensembl:ENSMUSP00000040505	150520179		Ensembl	GO_REF:0000107
HLX	Dog	regulation of DNA-templated transcription	involved_in	IEA	InterPro:IPR017970	150520179		InterPro	GO_REF:0000002
HLX	Dog	regulation of transcription by RNA polymerase II	involved_in	IEA	GO:0000981	150520179		GOC	GO_REF:0000108
HLX	Dog	skeletal muscle tissue development	acts_upstream_of_or_within	IEA	UniProtKB:Q61670 and ensembl:ENSMUSP00000040505	150520179		Ensembl	GO_REF:0000107
HLX	Dog	T-helper 1 cell differentiation	acts_upstream_of	IEA	UniProtKB:Q61670 and ensembl:ENSMUSP00000040505	150520179		Ensembl	GO_REF:0000107
HLX	Dog	T-helper 2 cell differentiation	acts_upstream_of	IEA	UniProtKB:Q61670 and ensembl:ENSMUSP00000040505	150520179		Ensembl	GO_REF:0000107

Cellular Component

Only show annotations with direct experimental evidence (0 objects hidden)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
HLX	Dog	nucleus	located_in	IEA	UniRule:UR000401037	150520179		UniProt	GO_REF:0000104
HLX	Dog	nucleus	located_in	IEA	UniProtKB-SubCell:SL-0191	150520179		UniProt	GO_REF:0000044
HLX	Dog	nucleus	located_in	IEA	UniProtKB-KW:KW-0539	150520179		UniProt	GO_REF:0000043

Molecular Function

Only show annotations with direct experimental evidence (0 objects hidden)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
HLX	Dog	DNA binding	enables	IEA	InterPro:IPR000047 more ...	150520179		InterPro	GO_REF:0000002
HLX	Dog	DNA binding	enables	IEA	UniProtKB-KW:KW-0238 and UniProtKB-KW:KW-0371	150520179		UniProt	GO_REF:0000043
HLX	Dog	DNA binding	enables	IEA	UniRule:UR000401037	150520179		UniProt	GO_REF:0000104
HLX	Dog	DNA-binding transcription factor activity, RNA polymerase II-specific	enables	IEA	InterPro:IPR017970	150520179		InterPro	GO_REF:0000002
HLX	Dog	protein binding	enables	ISO	UniProtKB:A8MQ03 more ...	9068941	PMID:32296183	IntAct	PMID:32296183
HLX	Dog	sequence-specific DNA binding	enables	IEA	UniProtKB:Q14774 and ensembl:ENSP00000355870	150520179		Ensembl	GO_REF:0000107
HLX	Dog	sequence-specific DNA binding	enables	IBA	PANTHER:PTN000677657 and UniProtKB:Q14774	150520179		GO_Central	GO_REF:0000033

Imported Annotations - PID (archival)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
HLX	Dog	interleukin-12 signaling pathway		ISO	HLX (Homo sapiens)	9068941		PID	PID:200045

PMID:15596718	PMID:22301074	PMID:30032202

HLX
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	38	15,538,744 - 15,543,686 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	38	15,539,029 - 15,542,152 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	38	15,580,303 - 15,585,398 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	38	15,575,409 - 15,580,508 (+)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	38	15,575,655 - 15,580,859 (+)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	38	15,582,466 - 15,587,573 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	38	15,937,032 - 15,942,341 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	38	16,230,020 - 16,235,130 (+)	NCBI		UU_Cfam_GSD_1.0

HLX
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	1	220,879,443 - 220,885,059 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	1	220,879,431 - 220,885,059 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	1	221,052,785 - 221,058,401 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	1	219,119,382 - 219,125,018 (+)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	1	217,441,153 - 217,446,790	NCBI
Celera	1	194,272,144 - 194,277,780 (+)	NCBI		Celera
Cytogenetic Map	1	q41	NCBI
HuRef	1	191,727,277 - 191,732,908 (+)	NCBI		HuRef
CHM1_1	1	222,325,244 - 222,330,902 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	1	220,119,233 - 220,124,841 (+)	NCBI		T2T-CHM13v2.0

Hlx
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	1	184,459,340 - 184,464,690 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	1	184,459,337 - 184,464,816 (-)	Ensembl		GRCm39 Ensembl
GRCm38	1	184,727,143 - 184,732,493 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	1	184,727,140 - 184,732,619 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	1	186,551,022 - 186,556,372 (-)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	1	186,427,931 - 186,433,396 (-)	NCBI		MGSCv36	mm8
Celera	1	191,689,162 - 191,694,499 (-)	NCBI		Celera
Cytogenetic Map	1	H5	NCBI
cM Map	1	88.97	NCBI

Hlx
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	13	98,811,852 - 98,817,264 (-)	NCBI		GRCr8
mRatBN7.2	13	96,280,335 - 96,285,750 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	13	96,280,339 - 96,285,750 (-)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	13	98,789,496 - 98,794,915 (-)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	13	100,185,399 - 100,190,810 (-)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	13	97,371,712 - 97,377,126 (-)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	13	102,637,967 - 102,643,376 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	13	102,637,769 - 102,643,223 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	13	107,315,400 - 107,320,809 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	13	100,685,757 - 100,691,658 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	13	100,874,799 - 100,902,762 (-)	NCBI
Celera	13	95,800,154 - 95,805,549 (-)	NCBI		Celera
Cytogenetic Map	13	q26	NCBI

Hlx
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955520	2,936,815 - 2,941,170 (-)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955520	2,937,131 - 2,941,170 (-)	NCBI	ChiLan1.0	ChiLan1.0

HLX
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	1	28,514,751 - 28,520,850 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	1	28,476,536 - 28,482,651 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	1	196,465,704 - 196,471,803 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	1	201,500,470 - 201,506,222 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	1	201,500,470 - 201,506,222 (+)	Ensembl	panpan1.1		panPan2

Hlx
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024409344	56,168,597 - 56,175,226 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936650	1,416,812 - 1,422,588 (-)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936650	1,416,825 - 1,422,595 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

HLX
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	10	10,264,244 - 10,269,879 (+)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	10	10,263,441 - 10,269,882 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	10	12,516,070 - 12,519,020 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

HLX
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	25	8,641,386 - 8,647,485 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	25	8,641,752 - 8,646,563 (-)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666055	8,920,798 - 8,926,903 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Hlx
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624835	4,223,511 - 4,227,979 (+)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624835	4,223,252 - 4,227,892 (+)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Variants in HLX
69 total Variants

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

adipose tissue	alimentary part of gastrointestinal system	circulatory system	ectoderm	endocrine system	endoderm	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	mesenchyme	mesoderm	nervous system	reproductive system	respiratory system
6	5	5	23	22	16	6	6	6	6	33	22	12	14	10


RefSeq Transcripts	XM_014111150	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038448765	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038522659	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038586437	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038650848	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AAEX04000038	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AY308810	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAAHUQ010000362	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAAQRD010000087	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAAUVH010000370	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	REHQ01000038	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSCAFT00000018023 ⟹ ENSCAFP00000016690

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
CanFam3.1 Ensembl	38	15,539,029 - 15,542,152 (+)	Ensembl

Ensembl Acc Id:

ENSCAFT00845053614 ⟹ ENSCAFP00845042128

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
ROS_Cfam_1.0 Ensembl	38	15,575,655 - 15,580,859 (+)	Ensembl

RefSeq Acc Id:

XM_014111150 ⟹ XP_013966625

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
CanFam3.1	38	15,538,744 - 15,543,686 (+)	NCBI
Dog10K_Boxer_Tasha	38	15,580,303 - 15,585,398 (+)	NCBI

Sequence:

show sequence

GGCCCCTCGCTCGCCTCCAGCCCGCGGGGAGCGCGGGCGCCGCGCCGCCTTTAAAGTGAGGCCAGGGGCCGCGGCTGGACCGGCCGGGATCCGGGCCTCGCCTCCTCCCTCGGGGGCGCTAGGGCTCC
CTGGCCTGTCTCCGGTGCGGACGGAGAAGCGAAAGCGGATCGTCCTCGGCTGCGCTGCCGCTGCCCCCGGGACCCCGCGCGCTCCCCTCCGCGCACCCATCCACCCGCCCGCTCGGCCGGGCCGGGCC
GCGGCGGCAGCTCGGCGCTCCCAGCCAGAATGTTCGCCGCCGGGCTGGCTCCCTTCTACGCCTCCAACTTCAGCCTCTGGTCGGCCGCCTACTGCTCCTCGGCCGGCCCGGGCGGCTGCTCCTTCCCG
CTGGACCCCGCCGCGGTCAAGAAGCCCTCCTTCTGCATCGCAGACATCCTGCACGCGGGCGTGGGGGAGCCGGGGGCGGCCCCGGACGGTCTGGCGGGGGCCTCGGCCGCCGCCCTCACCGCGCACTT
GGGCTCGGCTCACCCGCACGCGTCGTTCCAAGCCGCCGCCAGATCCCCGCTCCGACCCACCCCGGTGGTGGCGCCCTCCGAGGTCCCGGCTGGCTTCCCGCAGCGGCTGTCTCCGCTCTCAGCCGCCT
ACCACCACCATCACCCACAGCAACAGCAGCAGCAACAGCCGCCGCCGCCGCAGCAGCCTCCGCCGCCACTCCGGGCTGGCGCCCTGCAGCCCCCGGTCTCCGCGGCGCGGGTGCTCCCCAACCCCCCG
CATAGCGGCTCGGCCCCGGCCCCCTCTAGCAAGGACCTCAAATTTGGAATTGACCGCATTTTGTCTGCAGAATTTGACCCCAAAGTCAAGGAAGGCAACACGCTGAGAGACCTCACGTCGCTGCTGAC
CAGCGGGCGGCCCGCAGGGGTGCACCTCCCAGGCCTGCAGCCCTCCGCCGGCCAGTTCTTCGCGTCTCTAGATCCCATTAACGAGGCGTCTGCCATCCTGAGCCCCTTAAGCTCGAACCCGAGAAATT
CAGTTCAGCATCAGTTTCAAGACACGTTTCCAGGTCCCTACGCGGTGCTCACGAAGGACACCATGCCGCAGACATACAAAAGGAAGCGCTCATGGTCGCGGGCGGTCTTCTCCAACCTGCAGAGGAAA
GGCCTGGAGAAAAGGTTTGAGATTCAGAAGTATGTCACAAAGCCCGACCGAAAACAGCTGGCCGCGATGCTAGGCCTTACAGATGCGCAGGTGAAGGTGTGGTTCCAGAACCGGAGGATGAAGTGGCG
GCACTCCAAGGAGGCCCAGGCGCAGAAGGACAAGGACAAGGAGGCGGGCGAGAAGCCGTCGGGCGGGGCCGCGGCTGCGGACGGCGAGCAGGAGGAGCGGAGCCTCAGCCGCTCGGAGGGCGAGGCCG
AGAGCGAGAGCAGAGACTCCGAGTCCCTGGACATGGTCCCCAGCGACACGGAGCAGAATGAGGGGGCCGAGCGGCCCCTGCACCAGACCACG

hide sequence

RefSeq Acc Id:

XM_038448765 ⟹ XP_038304693

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
ROS_Cfam_1.0	38	15,575,409 - 15,580,508 (+)	NCBI

RefSeq Acc Id:

XM_038522659 ⟹ XP_038378587

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
UMICH_Zoey_3.1	38	15,582,466 - 15,587,573 (+)	NCBI

RefSeq Acc Id:

XM_038586437 ⟹ XP_038442365

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
UU_Cfam_GSD_1.0	38	16,230,020 - 16,235,130 (+)	NCBI

RefSeq Acc Id:

XM_038650848 ⟹ XP_038506776

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
UNSW_CanFamBas_1.0	38	15,937,032 - 15,942,341 (+)	NCBI


Protein RefSeqs	XP_013966625	(Get FASTA)	NCBI Sequence Viewer
	XP_038304693	(Get FASTA)	NCBI Sequence Viewer
	XP_038378587	(Get FASTA)	NCBI Sequence Viewer
	XP_038442365	(Get FASTA)	NCBI Sequence Viewer
	XP_038506776	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSCAFP00000016690.6
	ENSCAFP00030034675.1
	ENSCAFP00040025733.1
	ENSCAFP00845042128
	ENSCAFP00845042128.1

RefSeq Acc Id:	XP_013966625 ⟸ XM_014111150
- Peptide Label:	isoform X1
- UniProtKB:	A0A8C0JMS3 (UniProtKB/TrEMBL), A0A8C0P1U2 (UniProtKB/TrEMBL), A0A8I3QAU1 (UniProtKB/TrEMBL), A0A8C0STF3 (UniProtKB/TrEMBL)
- Sequence:	show sequence MFAAGLAPFYASNFSLWSAAYCSSAGPGGCSFPLDPAAVKKPSFCIADILHAGVGEPGAAPDGLAGASAAALTAHLGSAHPHASFQAAARSPLRPTPVVAPSEVPAGFPQRLSPLSAAYHHHHPQQQQ QQQPPPPQQPPPPLRAGALQPPVSAARVLPNPPHSGSAPAPSSKDLKFGIDRILSAEFDPKVKEGNTLRDLTSLLTSGRPAGVHLPGLQPSAGQFFASLDPINEASAILSPLSSNPRNSVQHQFQDTF PGPYAVLTKDTMPQTYKRKRSWSRAVFSNLQRKGLEKRFEIQKYVTKPDRKQLAAMLGLTDAQVKVWFQNRRMKWRHSKEAQAQKDKDKEAGEKPSGGAAAADGEQEERSLSRSEGEAESESRDSESL DMVPSDTEQNEGAERPLHQTT hide sequence

Ensembl Acc Id:

ENSCAFP00000016690 ⟸ ENSCAFT00000018023

RefSeq Acc Id:	XP_038378587 ⟸ XM_038522659
- Peptide Label:	isoform X1

RefSeq Acc Id:	XP_038506776 ⟸ XM_038650848
- Peptide Label:	isoform X2

RefSeq Acc Id:	XP_038304693 ⟸ XM_038448765
- Peptide Label:	isoform X1
- UniProtKB:	A0A8C0JMS3 (UniProtKB/TrEMBL), A0A8C0P1U2 (UniProtKB/TrEMBL), A0A8I3QAU1 (UniProtKB/TrEMBL), A0A8C0STF3 (UniProtKB/TrEMBL)

Protein Domains

Homeobox

Database	Acc Id	Source(s)
Ensembl Genes	ENSCAFG00000011340	Ensembl, UniProtKB/TrEMBL
	ENSCAFG00030021651	UniProtKB/TrEMBL
	ENSCAFG00040016062	UniProtKB/TrEMBL
	ENSCAFG00845030227	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSCAFT00000018023.6	UniProtKB/TrEMBL
	ENSCAFT00030039742.1	UniProtKB/TrEMBL
	ENSCAFT00040029622.1	UniProtKB/TrEMBL
	ENSCAFT00845053614	ENTREZGENE
	ENSCAFT00845053614.1	UniProtKB/TrEMBL
Gene3D-CATH	Homeodomain-like	UniProtKB/TrEMBL
InterPro	H2.0_Homeobox_TF	UniProtKB/TrEMBL
	Homeobox-like_sf	UniProtKB/TrEMBL
	Homeobox_CS	UniProtKB/TrEMBL
	Homeobox_dom	UniProtKB/TrEMBL
	Homeobox_metazoa	UniProtKB/TrEMBL
	HTH_motif	UniProtKB/TrEMBL
NCBI Gene	HLX	ENTREZGENE
PANTHER	H2.0-LIKE HOMEOBOX PROTEIN	UniProtKB/TrEMBL
	H2.0-LIKE HOMEOBOX PROTEIN	UniProtKB/TrEMBL
Pfam	Homeodomain	UniProtKB/TrEMBL
PRINTS	HOMEOBOX	UniProtKB/TrEMBL
	HTHREPRESSR	UniProtKB/TrEMBL
PROSITE	HOMEOBOX_1	UniProtKB/TrEMBL
	HOMEOBOX_2	UniProtKB/TrEMBL
SMART	HOX	UniProtKB/TrEMBL
Superfamily-SCOP	SSF46689	UniProtKB/TrEMBL
UniProt	A0A8C0JMS3	ENTREZGENE
	A0A8C0P1U2	ENTREZGENE, UniProtKB/TrEMBL
	A0A8C0STF3	ENTREZGENE, UniProtKB/TrEMBL
	A0A8I3QAU1	ENTREZGENE, UniProtKB/TrEMBL
VGNC ID	VGNC:50302	ENTREZGENE

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailable


InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailable


Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
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MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable

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Imported Disease Annotations - ClinVar

Imported Annotations - PID (archival)