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Gene: Hlx (H2.0-like homeobox) Mus musculus
Symbol: Hlx
Name: H2.0-like homeobox
Description: Predicted to have sequence-specific DNA binding activity. Involved in several processes, including animal organ development; enteric nervous system development; and regulation of T-helper cell differentiation. Predicted to localize to the nucleus. Is expressed in several structures, including branchial arch; central nervous system; embryo mesenchyme; genitourinary system; and gut. Orthologous to human HLX (H2.0 like homeobox); PARTICIPATES IN interleukin-12 signaling pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 4,4'-sulfonyldiphenol; 4-hydroxynon-2-enal.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: H2.0-like homeo box 1; H2.0-like homeobox protein; Hlx1; homeobox protein HLX1
Homo sapiens (human) : HLX (H2.0 like homeobox)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Hlx (H2.0-like homeobox)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Hlx (H2.0 like homeobox)
Pan paniscus (bonobo/pygmy chimpanzee) : HLX (H2.0 like homeobox)
Canis lupus familiaris (dog) : HLX (H2.0 like homeobox)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Hlx (H2.0 like homeobox)
Sus scrofa (pig) : HLX (H2.0 like homeobox)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm38 Ensembl1184,727,140 - 184,732,619 (-)Ensembl
GRCm381184,727,143 - 184,732,493 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv371186,551,022 - 186,556,372 (-)NCBIGRCm37mm9NCBIm37
MGSCv361186,427,931 - 186,433,396 (-)NCBImm8
Celera1191,689,162 - 191,694,499 (-)NCBICelera
Cytogenetic Map1 H5NCBI
cM Map188.97NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Hlx
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1551935
Created: 2005-09-30
Species: Mus musculus
Last Modified: 2019-11-27
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.