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Gene: NCF1 (neutrophil cytosolic factor 1) Canis lupus familiaris

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Symbol:

NCF1 (Ensembl: RCC1L)

Name:

neutrophil cytosolic factor 1

RGD ID:

12250216

Description:

ENCODES a protein that exhibits superoxide-generating NADPH oxidase activator activity (ortholog); INVOLVED IN cellular response to glucose stimulus (ortholog); cellular response to testosterone stimulus (ortholog); reactive oxygen species biosynthetic process (ortholog); ASSOCIATED WITH abdominal aortic aneurysm (ortholog); autosomal recessive chronic granulomatous disease 1 (ortholog); chronic granulomatous disease (ortholog); FOUND IN cytosol (ortholog); dendrite (ortholog); NADPH oxidase complex (ortholog); INTERACTS WITH pitavastatin; pitavastatin(1-)

Type:

protein-coding

RefSeq Status:

MODEL

Previously known as:

neutrophil cytosol factor 1; neutrophil cytosolic factor 1, (chronic granulomatous disease, autosomal 1); predicted neutrophil cytosolic factor 1

RGD Orthologs

Alliance Orthologs

More Info

more info ...

Latest Assembly:

CanFam3.1 - Dog CanFam3.1 Assembly

Position:

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	6	5,702,222 - 5,719,515 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	6	5,605,694 - 5,719,458 (-)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	6	7,403,701 - 7,421,192 (-)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	6	5,518,899 - 5,536,384 (-)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	6	5,518,899 - 5,540,134 (-)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	6	5,510,772 - 5,528,223 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	6	5,457,618 - 5,474,840 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	6	5,619,880 - 5,637,152 (-)	NCBI		UU_Cfam_GSD_1.0

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Only show annotations with direct experimental evidence (0 objects hidden)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
NCF1	Dog	Experimental Arthritis	severity	ISO	Ncf1 (Rattus norvegicus)	9068941	DNA:missense mutations:cds:p.M106V and p.M153T (rat)	RGD	PMID:12461526 and REF_RGD_ID:628543
NCF1	Dog	rheumatoid arthritis	induced	ISO	pristane	9068941	DNA:polymorphism:M153T (rat)	RGD	PMID:21275845 and REF_RGD_ID:41404729
NCF1	Dog	Williams-Beuren syndrome		ISO	NCF1 (Homo sapiens)	9068941	DNA:deletion	RGD	PMID:16532385 and REF_RGD_ID:1624399

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
NCF1	Dog	autosomal recessive chronic granulomatous disease 1		ISO	NCF1 (Homo sapiens)	8554872	ClinVar more ...	ClinVar	PMID:11133775 more ...
NCF1	Dog	chronic granulomatous disease		ISO	NCF1 (Homo sapiens)	8554872	ClinVar Annotator: match by term: Chronic granulomatous disease	ClinVar	PMID:11920901 more ...
NCF1	Dog	genetic disease		ISO	NCF1 (Homo sapiens)	8554872	ClinVar Annotator: match by term: Inborn genetic diseases	ClinVar
NCF1	Dog	hypertrophic cardiomyopathy 4		ISO	NCF1 (Homo sapiens)	8554872	ClinVar Annotator: match by term: Hypertrophic cardiomyopathy 4	ClinVar
NCF1	Dog	pleomorphic xanthoastrocytoma		ISO	NCF1 (Homo sapiens)	8554872	ClinVar Annotator: match by term: Pleomorphic xanthoastrocytoma	ClinVar	PMID:28299358
NCF1	Dog	X-linked chronic granulomatous disease		ISO	NCF1 (Homo sapiens)	8554872	ClinVar Annotator: match by term: CYTOCHROME b-NEGATIVE GRANULOMATOUS DISEASE more ...	ClinVar	PMID:25741868

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
NCF1	Dog	abdominal aortic aneurysm		ISO	NCF1 (Homo sapiens)	9068941	CTD Direct Evidence: marker/mechanism	CTD	PMID:16864727
NCF1	Dog	diabetes mellitus		ISO	NCF1 (Homo sapiens)	9068941	CTD Direct Evidence: marker/mechanism	CTD	PMID:23723366
NCF1	Dog	end stage renal disease		ISO	NCF1 (Homo sapiens)	9068941	CTD Direct Evidence: marker/mechanism	CTD	PMID:19420110
NCF1	Dog	essential hypertension		ISO	NCF1 (Homo sapiens)	9068941	CTD Direct Evidence: marker/mechanism	CTD	PMID:34453990
NCF1	Dog	Experimental Diabetes Mellitus		ISO	NCF1 (Homo sapiens)	9068941	CTD Direct Evidence: marker/mechanism	CTD	PMID:14871415 and PMID:16380483
NCF1	Dog	Hypercholesterolemia		ISO	NCF1 (Homo sapiens)	9068941	CTD Direct Evidence: marker/mechanism	CTD	PMID:14871415
NCF1	Dog	hypertension		ISO	NCF1 (Homo sapiens)	9068941	CTD Direct Evidence: marker/mechanism	CTD	PMID:16331104 more ...
NCF1	Dog	Hypothermia		ISO	NCF1 (Homo sapiens)	9068941	CTD Direct Evidence: therapeutic	CTD	PMID:30366073
NCF1	Dog	intracranial aneurysm		ISO	NCF1 (Homo sapiens)	9068941	CTD Direct Evidence: marker/mechanism	CTD	PMID:19381132
NCF1	Dog	Neoplastic Cell Transformation		ISO	NCF1 (Homo sapiens)	9068941	CTD Direct Evidence: marker/mechanism	CTD	PMID:21742780
NCF1	Dog	rheumatoid arthritis		ISO	NCF1 (Homo sapiens)	9068941	CTD Direct Evidence: marker/mechanism	CTD	PMID:12833524 and PMID:28135245
NCF1	Dog	Sjogren's syndrome		ISO	NCF1 (Homo sapiens)	9068941	CTD Direct Evidence: marker/mechanism	CTD	PMID:28135245
NCF1	Dog	systemic lupus erythematosus		ISO	NCF1 (Homo sapiens)	9068941	CTD Direct Evidence: marker/mechanism	CTD	PMID:28135245

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
NCF1	Dog	autosomal recessive chronic granulomatous disease 1		ISO	NCF1 (Homo sapiens)	7240710		OMIM

Only show annotations with direct experimental evidence (0 objects hidden)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
NCF1	Dog	pitavastatin	decreases expression	EXP		6480464	pitavastatin results in decreased expression of NCF1 mRNA	CTD	PMID:15502390
NCF1	Dog	pitavastatin(1-)	decreases expression	EXP		6480464	pitavastatin results in decreased expression of NCF1 mRNA	CTD	PMID:15502390

Biological Process

Only show annotations with direct experimental evidence (0 objects hidden)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
NCF1	Dog	cellular defense response	acts_upstream_of_or_within	IEA	UniProtKB:Q09014 and ensembl:ENSMUSP00000106906	150520179		Ensembl	GO_REF:0000107
NCF1	Dog	cellular response to glucose stimulus		ISO	Ncf1 (Rattus norvegicus)	9068941		RGD	PMID:25512346 and REF_RGD_ID:151708735
NCF1	Dog	cellular response to testosterone stimulus		ISO	Ncf1 (Rattus norvegicus)	9068941		RGD	PMID:25512346 and REF_RGD_ID:151708735
NCF1	Dog	defense response to bacterium	acts_upstream_of_or_within	IEA	UniProtKB:Q09014 and ensembl:ENSMUSP00000106906	150520179		Ensembl	GO_REF:0000107
NCF1	Dog	defense response to fungus	acts_upstream_of_or_within	IEA	UniProtKB:Q09014 and ensembl:ENSMUSP00000106906	150520179		Ensembl	GO_REF:0000107
NCF1	Dog	defense response to Gram-positive bacterium	acts_upstream_of_or_within	IEA	UniProtKB:Q09014 and ensembl:ENSMUSP00000106906	150520179		Ensembl	GO_REF:0000107
NCF1	Dog	epithelial cell proliferation	acts_upstream_of_or_within	IEA	UniProtKB:Q09014 and ensembl:ENSMUSP00000106906	150520179		Ensembl	GO_REF:0000107
NCF1	Dog	hydrogen peroxide biosynthetic process	acts_upstream_of_or_within	IEA	UniProtKB:Q09014 and ensembl:ENSMUSP00000106906	150520179		Ensembl	GO_REF:0000107
NCF1	Dog	inflammatory response	acts_upstream_of_or_within	IEA	UniProtKB:Q09014 and ensembl:ENSMUSP00000106906	150520179		Ensembl	GO_REF:0000107
NCF1	Dog	leukocyte mediated cytotoxicity	acts_upstream_of_or_within	IEA	UniProtKB:Q09014 and ensembl:ENSMUSP00000106906	150520179		Ensembl	GO_REF:0000107
NCF1	Dog	leukotriene metabolic process	acts_upstream_of_or_within	IEA	UniProtKB:Q09014 and ensembl:ENSMUSP00000106906	150520179		Ensembl	GO_REF:0000107
NCF1	Dog	neutrophil-mediated killing of fungus	acts_upstream_of_or_within	IEA	UniProtKB:Q09014 and ensembl:ENSMUSP00000106906	150520179		Ensembl	GO_REF:0000107
NCF1	Dog	neutrophil-mediated killing of gram-positive bacterium	acts_upstream_of_or_within	IEA	UniProtKB:Q09014 and ensembl:ENSMUSP00000106906	150520179		Ensembl	GO_REF:0000107
NCF1	Dog	protein targeting to membrane	involved_in	IEA	UniProtKB:P14598 and ensembl:ENSP00000289473	150520179		Ensembl	GO_REF:0000107
NCF1	Dog	reactive oxygen species biosynthetic process		ISO	Ncf1 (Rattus norvegicus)	9068941		RGD	PMID:21275845 and REF_RGD_ID:41404729
NCF1	Dog	regulation of respiratory burst involved in inflammatory response		ISO	Ncf1 (Rattus norvegicus)	9068941		RGD	PMID:21275845 and REF_RGD_ID:41404729
NCF1	Dog	respiratory burst		ISO	Ncf1 (Rattus norvegicus)	9068941		RGD	PMID:12461526 and REF_RGD_ID:628543
NCF1	Dog	respiratory burst	involved_in	IBA	MGI:97283 more ...	150520179		GO_Central	GO_REF:0000033
NCF1	Dog	respiratory burst	acts_upstream_of_or_within	IEA	UniProtKB:Q09014 and ensembl:ENSMUSP00000106906	150520179		Ensembl	GO_REF:0000107
NCF1	Dog	respiratory burst involved in defense response	acts_upstream_of_or_within	IEA	UniProtKB:Q09014 and ensembl:ENSMUSP00000106906	150520179		Ensembl	GO_REF:0000107
NCF1	Dog	response to bacterium	acts_upstream_of_or_within	IEA	UniProtKB:Q09014 and ensembl:ENSMUSP00000106906	150520179		Ensembl	GO_REF:0000107
NCF1	Dog	response to yeast	acts_upstream_of_or_within	IEA	UniProtKB:Q09014 and ensembl:ENSMUSP00000106906	150520179		Ensembl	GO_REF:0000107
NCF1	Dog	superoxide anion generation	acts_upstream_of_or_within_positive_effect	ISO	NCF1 (Homo sapiens)	9068941	PMID:2547247	GO_Central	PMID:2547247
NCF1	Dog	superoxide anion generation	acts_upstream_of_or_within	IEA	UniProtKB:Q09014 and ensembl:ENSMUSP00000106906	150520179		Ensembl	GO_REF:0000107
NCF1	Dog	superoxide anion generation	involved_in	IEA	UniProtKB:P14598 and ensembl:ENSP00000289473	150520179		Ensembl	GO_REF:0000107
NCF1	Dog	superoxide anion generation	involved_in	IBA	MGI:97283 more ...	150520179		GO_Central	GO_REF:0000033

Cellular Component

Only show annotations with direct experimental evidence (0 objects hidden)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
NCF1	Dog	cytoplasm	located_in	IEA	UniProtKB-KW:KW-0963	150520179		UniProt	GO_REF:0000043
NCF1	Dog	cytoplasm	is_active_in	IBA	MGI:109186 more ...	150520179		GO_Central	GO_REF:0000033
NCF1	Dog	cytoplasm	located_in	IEA	UniProtKB-SubCell:SL-0086	150520179		UniProt	GO_REF:0000044
NCF1	Dog	cytoplasm	located_in	IEA	UniProtKB:Q09014 and ensembl:ENSMUSP00000106906	150520179		Ensembl	GO_REF:0000107
NCF1	Dog	cytoplasm	located_in	IEA	InterPro:IPR001655	150520179		InterPro	GO_REF:0000002
NCF1	Dog	cytoplasmic side of plasma membrane	located_in	IEA	UniProtKB:P14598 and ensembl:ENSP00000289473	150520179		Ensembl	GO_REF:0000107
NCF1	Dog	cytosol	located_in	IEA	UniProtKB:P14598 and ensembl:ENSP00000289473	150520179		Ensembl	GO_REF:0000107
NCF1	Dog	cytosol		ISO	Ncf1 (Rattus norvegicus)	9068941	MMO:0000679	RGD	PMID:24445059 and REF_RGD_ID:329970277
NCF1	Dog	dendrite		ISO	Ncf1 (Rattus norvegicus)	9068941		RGD	PMID:15804439 more ...
NCF1	Dog	membrane	located_in	IEA	UniProtKB:P14598 more ...	150520179		Ensembl	GO_REF:0000107
NCF1	Dog	NADPH oxidase complex		ISO	Ncf1 (Rattus norvegicus)	9068941		RGD	PMID:12241540 and REF_RGD_ID:2291907
NCF1	Dog	NADPH oxidase complex	part_of	IBA	PANTHER:PTN002696093 more ...	150520179		GO_Central	GO_REF:0000033
NCF1	Dog	NADPH oxidase complex	part_of	IEA	UniProtKB:P14598 and ensembl:ENSP00000289473	150520179		Ensembl	GO_REF:0000107
NCF1	Dog	neuronal cell body		ISO	Ncf1 (Rattus norvegicus)	9068941		RGD	PMID:15804439 more ...
NCF1	Dog	plasma membrane	located_in	IEA	UniProtKB:P14598 and ensembl:ENSP00000289473	150520179		Ensembl	GO_REF:0000107
NCF1	Dog	plasma membrane		ISO	Ncf1 (Rattus norvegicus)	9068941	MMO:0000679	RGD	PMID:24445059 and REF_RGD_ID:329970277

Molecular Function

Only show annotations with direct experimental evidence (0 objects hidden)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
NCF1	Dog	phosphatidylinositol binding	enables	IEA	InterPro:IPR001683 and InterPro:IPR036871	150520179		InterPro	GO_REF:0000002
NCF1	Dog	phosphatidylinositol binding	enables	IEA	UniProtKB:P14598 and ensembl:ENSP00000289473	150520179		Ensembl	GO_REF:0000107
NCF1	Dog	phosphatidylinositol-3,4-bisphosphate binding	enables	IEA	UniProtKB:P14598 and ensembl:ENSP00000289473	150520179		Ensembl	GO_REF:0000107
NCF1	Dog	protein binding	enables	ISO	UniProtKB:P11142	9068941	PMID:25910212	IntAct	PMID:25910212
NCF1	Dog	protein binding	enables	ISO	PR:O70145 and PR:P97369	9068941	PMID:9490028	MGI	PMID:9490028
NCF1	Dog	protein binding	enables	ISO	UniProtKB:Q99LX0	9068941	PMID:26021615	UniProt	PMID:26021615
NCF1	Dog	protein binding	enables	ISO	UniProtKB:P19878 and UniProtKB:Q15080	9068941	PMID:30630949	DisProt	PMID:30630949
NCF1	Dog	protein binding	enables	ISO	UniProtKB:P14598	9068941	PMID:12732142	DisProt	PMID:12732142
NCF1	Dog	protein binding	enables	ISO	UniProtKB:P06396 more ...	9068941	PMID:32814053	IntAct	PMID:32814053
NCF1	Dog	protein binding	enables	ISO	UniProtKB:P04899 and UniProtKB:P19878	9068941	PMID:16782902	IntAct	PMID:16782902
NCF1	Dog	protein binding	enables	ISO	UniProtKB:P19878 and UniProtKB:Q9BUZ4	9068941	PMID:32296183	IntAct	PMID:32296183
NCF1	Dog	protein binding	enables	ISO	UniProtKB:Q9BUZ4	9068941	PMID:16330715	IntAct	PMID:16330715
NCF1	Dog	protein binding	enables	ISO	UniProtKB:P19878 and UniProtKB:Q15080	9068941	PMID:15657040	IntAct	PMID:15657040
NCF1	Dog	protein binding	enables	ISO	UniProtKB:P19878	9068941	PMID:16297854 more ...	IntAct	PMID:16297854 more ...
NCF1	Dog	protein binding	enables	ISO	UniProtKB:P31146	9068941	PMID:11094157	UniProt	PMID:11094157
NCF1	Dog	protein binding	enables	ISO	UniProtKB:P78325	9068941	PMID:25825872	IntAct	PMID:25825872
NCF1	Dog	protein binding	enables	ISO	UniProtKB:P13498	9068941	PMID:11733522 more ...	IntAct	PMID:11733522 more ...
NCF1	Dog	protein binding	enables	ISO	UniProtKB:Q8IZP0	9068941	PMID:12681507	IntAct	PMID:12681507
NCF1	Dog	protein binding	enables	ISO	UniProtKB:Q05513	9068941	PMID:27040869	IntAct	PMID:27040869
NCF1	Dog	protein binding	enables	ISO	UniProtKB:P60709	9068941	PMID:16375898	IntAct	PMID:16375898
NCF1	Dog	SH3 domain binding	enables	IEA	UniProtKB:P14598 and ensembl:ENSP00000289473	150520179		Ensembl	GO_REF:0000107
NCF1	Dog	superoxide-generating NAD(P)H oxidase activity	enables	IEA	UniProtKB:P14598 and ensembl:ENSP00000289473	150520179		Ensembl	GO_REF:0000107
NCF1	Dog	superoxide-generating NADPH oxidase activator activity		ISO	Ncf1 (Rattus norvegicus)	9068941		RGD	PMID:16040349 and REF_RGD_ID:1600567
NCF1	Dog	superoxide-generating NADPH oxidase activator activity	enables	IBA	MGI:1919143 more ...	150520179		GO_Central	GO_REF:0000033
NCF1	Dog	superoxide-generating NADPH oxidase activator activity	enables	IEA	InterPro:IPR001655	150520179		InterPro	GO_REF:0000002
NCF1	Dog	superoxide-generating NADPH oxidase activator activity	enables	IEA	UniProtKB:Q09014 and ensembl:ENSMUSP00000106906	150520179		Ensembl	GO_REF:0000107

PMID:16381931	PMID:17612411	PMID:19168727	PMID:22301074	PMID:30032202

NCF1
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	6	5,702,222 - 5,719,515 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	6	5,605,694 - 5,719,458 (-)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	6	7,403,701 - 7,421,192 (-)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	6	5,518,899 - 5,536,384 (-)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	6	5,518,899 - 5,540,134 (-)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	6	5,510,772 - 5,528,223 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	6	5,457,618 - 5,474,840 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	6	5,619,880 - 5,637,152 (-)	NCBI		UU_Cfam_GSD_1.0

NCF1
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	7	74,774,011 - 74,789,315 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	7	74,774,011 - 74,789,315 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	7	74,188,358 - 74,203,659 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	7	73,826,245 - 73,841,595 (+)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	7	74,017,096 - 74,032,410	NCBI
Cytogenetic Map	7	q11.23	NCBI
CHM1_1	7	74,333,378 - 74,348,792 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	7	75,976,304 - 75,991,631 (+)	NCBI		T2T-CHM13v2.0
CRA_TCAGchr7v2	7	73,521,373 - 73,536,784	NCBI

Ncf1
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	5	134,248,907 - 134,258,479 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	5	134,248,907 - 134,258,479 (-)	Ensembl		GRCm39 Ensembl
GRCm38	5	134,220,053 - 134,229,628 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	5	134,220,053 - 134,229,625 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	5	134,696,130 - 134,705,495 (-)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	5	134,504,886 - 134,514,206 (-)	NCBI		MGSCv36	mm8
Celera	5	131,223,583 - 131,232,950 (-)	NCBI		Celera
Cytogenetic Map	5	G2	NCBI
cM Map	5	74.47	NCBI

Ncf1
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	12	28,121,816 - 28,131,080 (+)	NCBI		GRCr8
mRatBN7.2	12	22,485,382 - 22,494,647 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	12	22,485,451 - 22,494,646 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	12	23,628,473 - 23,637,751 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	12	24,239,570 - 24,248,848 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	12	23,305,038 - 23,314,250 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	12	25,497,104 - 25,506,300 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	12	25,497,104 - 25,506,300 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	12	27,505,793 - 27,514,989 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	12	23,578,097 - 23,587,292 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	12	23,441,312 - 23,450,507 (+)	NCBI
Celera	12	24,246,402 - 24,255,599 (+)	NCBI		Celera
Cytogenetic Map	12	q12	NCBI

Ncf1
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955456	13,354,011 - 13,363,891 (-)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955456	13,353,780 - 13,363,956 (-)	NCBI	ChiLan1.0	ChiLan1.0

NCF1
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	6	90,107,213 - 90,128,059 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	7	138,371,836 - 138,392,363 (-)	NCBI		NHGRI_mPanPan1
PanPan1.1	7	81,917,167 - 81,932,589 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	7	81,917,167 - 81,932,589 (+)	Ensembl	panpan1.1		panPan2

Ncf1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024409344	130,406,743 - 130,420,026 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936543	3,617,372 - 3,630,997 (+)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936543	3,617,369 - 3,630,990 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

NCF1
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	3	11,820,266 - 11,839,354 (+)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	3	11,820,367 - 11,834,394 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	3	11,538,926 - 11,552,955 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

NCF1
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	28	8,334,172 - 8,349,828 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	28	8,332,772 - 8,349,804 (-)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666070	8,253,552 - 8,269,564 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Ncf1
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624740	13,429,476 - 13,439,807 (-)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624740	13,428,375 - 13,439,915 (-)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Variants in NCF1
221 total Variants

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

adipose tissue	alimentary part of gastrointestinal system	circulatory system	ectoderm	endocrine system	endoderm	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	mesenchyme	mesoderm	nervous system	reproductive system	respiratory system
6	5	5	23	22	16	6	6	6	6	33	22	12	14	10


RefSeq Transcripts	XM_038477813	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038539053	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038603159	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038667852	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_844481	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AAEX04000006	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BR000287	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAAHUQ010000067	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAAQRD010000090	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAAUVH010000065	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	REHQ01000006	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSCAFT00000018027 ⟹ ENSCAFP00000016694

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
CanFam3.1 Ensembl	6	5,611,277 - 5,632,156 (-)	Ensembl

Ensembl Acc Id:

ENSCAFT00000018106 ⟹ ENSCAFP00000016769

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
CanFam3.1 Ensembl	6	5,703,162 - 5,719,458 (-)	Ensembl

Ensembl Acc Id:

ENSCAFT00000068955 ⟹ ENSCAFP00000055915

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
CanFam3.1 Ensembl	6	5,610,691 - 5,719,439 (-)	Ensembl

Ensembl Acc Id:

ENSCAFT00000078904 ⟹ ENSCAFP00000045081

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
CanFam3.1 Ensembl	6	5,605,694 - 5,719,439 (-)	Ensembl

Ensembl Acc Id:

ENSCAFT00845003394 ⟹ ENSCAFP00845002697

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
ROS_Cfam_1.0 Ensembl	6	5,518,899 - 5,536,363 (-)	Ensembl

Ensembl Acc Id:

ENSCAFT00845003414 ⟹ ENSCAFP00845002712

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
ROS_Cfam_1.0 Ensembl	6	5,519,176 - 5,540,134 (-)	Ensembl

RefSeq Acc Id:

XM_038477813 ⟹ XP_038333741

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
UMICH_Zoey_3.1	6	5,510,772 - 5,528,223 (-)	NCBI

RefSeq Acc Id:

XM_038539053 ⟹ XP_038394981

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
UU_Cfam_GSD_1.0	6	5,619,880 - 5,637,152 (-)	NCBI

RefSeq Acc Id:

XM_038603159 ⟹ XP_038459087

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
UNSW_CanFamBas_1.0	6	5,457,618 - 5,474,840 (-)	NCBI

RefSeq Acc Id:

XM_038667852 ⟹ XP_038523780

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
ROS_Cfam_1.0	6	5,518,899 - 5,536,384 (-)	NCBI

RefSeq Acc Id:

XM_844481 ⟹ XP_849574

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
CanFam3.1	6	5,702,222 - 5,719,515 (-)	NCBI
Dog10K_Boxer_Tasha	6	7,403,701 - 7,421,192 (-)	NCBI

Sequence:

show sequence

AGTGACTTCCTCTTTCCACCCCATTTAAGGCCCAGCTGGGAGCGCCCCACAGGAGGGGAGGCCCCGCAGCCCAGCCATGGGGGACACCTTCATCCGCCACATCGCCCTTCTGGGCTTCGAGAAGCGCT
TCGTCCCCAGCCAGCACTACGTCTACATGTTTCTGGTGAAGTGGCACGACCTGTCGGAGAAGGTGGTCTACCGGCGCTTCACCGAGATCTACGAGTTCCACAAAATGTTAAAGGAAATGTTTCCTATC
GAGGCAGGGGACATCAACCCAGAGAACAGGATCATCCCGCACCTGCCAGCCCCGCGGTGGTTCGATGGGCAGCGGGCGGCCGAGAGTCGCCAGGGCACGCTCACCGAGTACTACAACACGCTCATGGG
TCTGCCTGTCAAGATCTCCCGCTGCCCCCAACTCCTCGACTTCTTTAGAGTGCGCCCCGACGACCTCAAGCTTCCCACGGACAGCCAGGTGAAAAAGCCAGAGACCTACTTGGTGCCCAAAGACGGCA
AGAGCAGTGTCACGGACATCACAGGCCCCATCATCCTGCAGACGTACCGTGCCATTGCTGACTTCGAGAAGACCTCGAGCTCCCAGATGGCTCTAGCCACGGGTGACGTGGTGGACGTCGTGGAGAAG
AGCGAGAGTGGCTGGTGGTTCTGCCAAACGAAGACAAAGCGAGGTTGGGTCCCGGCGTCCTACTTGGAGCCCTTGGACAGTCCTGATGAGGCAGAGGACCCAGAGCCCAACTACGAAGGTGAGCCCTA
TGTCACCATCAAAGCCTATACTGCCGAGATGGAGGATGAAATGTCCCTGCAGGAAGGCGAAGCCATCGAAGTCATTCATAAGCTCCTGGATGGTTGGTGGGTCGTCAGGAAAGACGACATCACCGGCT
ACTTCCCATCCATGTACCTACAGAAGTCCGGGCAGGATGCTGCCCAGGCGCATCGCCAGATCAAGAGCCGAGGGGCCCCGCCCCGCAGGTCGTCCATCCGCAACGCGCACAGCATCCACCAGCGATCG
CGGAAGCGCCTCAGCCAGGACACCTATCGGCGCAACAGCGTCCGTTTTCTGCAGCAGCGCCGCCGTCAGGCGCGGCCCGGACCGCGGAGCCCGGGGAGCCCGCGCGAGGAGCAGCCAGCGACCCAGCC
CGCGAAGCCACAGCCCGCGGTGCCCCCGCGGCCCAGCGCAGACCTTATCCTGCACCGATGCAGCGAGAGCACCAAGCGGAAGCTGGCGTCTTCCGTCTGAGGCCGGGTCGCCTCCCCTAGATGGCGTC
CTAGCCCCTCCGCCCTGTCGGGTCCCATCCCTGTATATACGTGTATAGATCCGGAGGTCTGGATGCCTCTGGCAGCCCCGGCCCCGCCCCACCTAACGGCTCGGCCGCTCATAGTAAATGCTGTTTGG
AGTGGACAGAGGCTCTGCAGAGCAGCCGGGCGGGCTGGGCTGGGCACGCCTTTGGGGATATTTATAAAATAAGAACTGAAGGCTGTGAGTTCTGCTGGGGCGGGAGGTTGGGGGAAGTTGCAAGAACC
AAGGTCCGGTTGCACTCTGCCCTGGCCTTGGCCGAGACTAAGTTTGCACGGGGCCAAGTGCACCCGTTCCCCCCTGCCCCCCCCACTGCTGGCTGTTTGGACAGAAGCTGCCTGCTAAAACTTTGGTA
CCACTGCAGAAGAGTCCTAAAGAAGGGTGCCACAGTGTGCAGGGTGTGCACCTTAGTTCGGTGACAAAGAAAATTGGTAATTTAGGTATACGGAGGGAGCACCTCTGATTTATTCACTGAAAGGCTGC
CCAGTTAGGAGGTTGTACCAGAAAGCAATTATTCATTGATGAACAGACCCTCATCGCCCCCACAAGCAACTGCTGCCAGCCTTTGGCCTCAAAGTCTTTGCTGGTGGATCTTTTGCAAAATGCAAAGA
CACCAGGGTGCAGCCCGGAGCTGCAAATCTTACAAAAGCAGCCGCTTATCAAGAAGGCAGCTGCCCCTCCTGTATGGGAGGTGGCACAAGAGGATGGGAGAGGCTGGTCCCTTGGAGGGGGGGCTGAT
GCTTCTCAAGAGAACAACTTGAGGGTCACAACAACTGAAAGAGACCTTGAGAAGGTCACTGGGCCCTTTATTTGCATTTTTGCAGACTTGGTTTGCTGGAAAAGTCCAGCCCATCAAGTGCTATCATG
CAAAGCTGTGGGAGAATTAACCACTGCGAATCCCAACCCCTTTGCTTGTTCAGTTGCAATTAAAATAAAAAACTGTGTAAGATAAAATCTTG

hide sequence


Protein RefSeqs	XP_038333741	(Get FASTA)	NCBI Sequence Viewer
	XP_038394981	(Get FASTA)	NCBI Sequence Viewer
	XP_038459087	(Get FASTA)	NCBI Sequence Viewer
	XP_038523780	(Get FASTA)	NCBI Sequence Viewer
	XP_849574	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSCAFP00000016769.3
	ENSCAFP00000045081.1
	ENSCAFP00000055915.1
	ENSCAFP00000072831.1
	ENSCAFP00030025041.1
	ENSCAFP00040013068.1
	ENSCAFP00040013095.1
	ENSCAFP00040013138.1
	ENSCAFP00040013273.1
	ENSCAFP00845002697
	ENSCAFP00845002697.1
	ENSCAFP00845002712.1
GenBank Protein	FAA00354	(Get FASTA)	NCBI Sequence Viewer

RefSeq Acc Id:	XP_849574 ⟸ XM_844481
- Peptide Label:	isoform X1
- UniProtKB:	A0A8C0RKZ9 (UniProtKB/TrEMBL), A0A8I3MJA0 (UniProtKB/TrEMBL), A0A8C0JZK7 (UniProtKB/TrEMBL)
- Sequence:	show sequence MGDTFIRHIALLGFEKRFVPSQHYVYMFLVKWHDLSEKVVYRRFTEIYEFHKMLKEMFPIEAGDINPENRIIPHLPAPRWFDGQRAAESRQGTLTEYYNTLMGLPVKISRCPQLLDFFRVRPDDLKLP TDSQVKKPETYLVPKDGKSSVTDITGPIILQTYRAIADFEKTSSSQMALATGDVVDVVEKSESGWWFCQTKTKRGWVPASYLEPLDSPDEAEDPEPNYEGEPYVTIKAYTAEMEDEMSLQEGEAIEVI HKLLDGWWVVRKDDITGYFPSMYLQKSGQDAAQAHRQIKSRGAPPRRSSIRNAHSIHQRSRKRLSQDTYRRNSVRFLQQRRRQARPGPRSPGSPREEQPATQPAKPQPAVPPRPSADLILHRCSESTK RKLASSV hide sequence

Ensembl Acc Id:

ENSCAFP00000055915 ⟸ ENSCAFT00000068955

Ensembl Acc Id:

ENSCAFP00000045081 ⟸ ENSCAFT00000078904

Ensembl Acc Id:

ENSCAFP00000016694 ⟸ ENSCAFT00000018027

Ensembl Acc Id:

ENSCAFP00000016769 ⟸ ENSCAFT00000018106

Protein Domains

PX SH3

Database	Acc Id	Source(s)
Ensembl Genes	ENSCAFG00000011334	Ensembl, UniProtKB/TrEMBL
	ENSCAFG00030015582	UniProtKB/TrEMBL
	ENSCAFG00040008078	UniProtKB/TrEMBL
	ENSCAFG00845001935	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSCAFT00000018106.5	UniProtKB/TrEMBL
	ENSCAFT00000068955.2	UniProtKB/TrEMBL
	ENSCAFT00000078904.2	UniProtKB/TrEMBL
	ENSCAFT00000098342.1	UniProtKB/TrEMBL
	ENSCAFT00030028720.1	UniProtKB/TrEMBL
	ENSCAFT00040015090.1	UniProtKB/TrEMBL
	ENSCAFT00040015122.1	UniProtKB/TrEMBL
	ENSCAFT00040015167.1	UniProtKB/TrEMBL
	ENSCAFT00040015320.1	UniProtKB/TrEMBL
	ENSCAFT00845003394	ENTREZGENE
	ENSCAFT00845003394.1	UniProtKB/TrEMBL
	ENSCAFT00845003414.1	UniProtKB/TrEMBL
Gene3D-CATH	2.130.10.30	UniProtKB/TrEMBL
	3.30.1520.10	UniProtKB/TrEMBL
	SH3 Domains	UniProtKB/TrEMBL
InterPro	Mitochondrial_GEF_domain	UniProtKB/TrEMBL
	NADPH_Oxidase/PX-Domain	UniProtKB/TrEMBL
	NADPH_oxidase_p47Phox_C	UniProtKB/TrEMBL
	NCF1_SH3_1	UniProtKB/TrEMBL
	NCF1_SH3_2	UniProtKB/TrEMBL
	NECFESHC	UniProtKB/TrEMBL
	P47PHOX	UniProtKB/TrEMBL
	PX_dom	UniProtKB/TrEMBL
	PX_dom_sf	UniProtKB/TrEMBL
	PX_p47phox	UniProtKB/TrEMBL
	RCC1/BLIP-II	UniProtKB/TrEMBL
	Reg_chr_condens	UniProtKB/TrEMBL
	SH3-like_dom_sf	UniProtKB/TrEMBL
	SH3_domain	UniProtKB/TrEMBL
KEGG Report	cfa:607700	UniProtKB/TrEMBL
NCBI Gene	NCF1	ENTREZGENE
PANTHER	PTHR15706:SF6	UniProtKB/TrEMBL
	RCC1-LIKE G EXCHANGING FACTOR-LIKE PROTEIN	UniProtKB/TrEMBL
	RCC1-LIKE G EXCHANGING FACTOR-LIKE PROTEIN	UniProtKB/TrEMBL
	SH3 MULTIPLE DOMAIN	UniProtKB/TrEMBL
Pfam	NECFESHC	UniProtKB/TrEMBL
	p47_phox_C	UniProtKB/TrEMBL
	PF00787	UniProtKB/TrEMBL
	RCC1	UniProtKB/TrEMBL
	RCC1_2	UniProtKB/TrEMBL
	SH3_1	UniProtKB/TrEMBL
PRINTS	P47PHOX	UniProtKB/TrEMBL
	RCCNDNSATION	UniProtKB/TrEMBL
	SH3DOMAIN	UniProtKB/TrEMBL
PROSITE	PS50195	UniProtKB/TrEMBL
	RCC1_3	UniProtKB/TrEMBL
	SH3	UniProtKB/TrEMBL
SMART	SH3	UniProtKB/TrEMBL
	SM00312	UniProtKB/TrEMBL
Superfamily-SCOP	RCC1/BLIP-II	UniProtKB/TrEMBL
	SSF50044	UniProtKB/TrEMBL
	SSF64268	UniProtKB/TrEMBL
UniProt	A0A8C0JZK7	ENTREZGENE
	A0A8C0QEQ1_CANLF	UniProtKB/TrEMBL
	A0A8C0QEW7_CANLF	UniProtKB/TrEMBL
	A0A8C0QJD7_CANLF	UniProtKB/TrEMBL
	A0A8C0RKZ9	ENTREZGENE, UniProtKB/TrEMBL
	A0A8I3MJA0	ENTREZGENE, UniProtKB/TrEMBL
	A0A8I3MKD2_CANLF	UniProtKB/TrEMBL
	A0A8P0P582_CANLF	UniProtKB/TrEMBL
	A0A8P0PND8_CANLF	UniProtKB/TrEMBL
	A0A8P0SY56_CANLF	UniProtKB/TrEMBL
	A7E3M5_CANLF	UniProtKB/TrEMBL
VGNC ID	VGNC:54048	ENTREZGENE

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailable


InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailable


Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
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