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Gene: PTGR1 (prostaglandin reductase 1) Canis lupus familiaris

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Symbol:

PTGR1

Name:

prostaglandin reductase 1

RGD ID:

12247046

Description:

ENCODES a protein that exhibits 13-lipoxin reductase activity (ortholog); leukotriene B4 12-hydroxy dehydrogenase activity (ortholog); INVOLVED IN alkene metabolic process (ortholog); leukotriene B4 metabolic process (ortholog); lipoxin A4 metabolic process (ortholog); ASSOCIATED WITH autism spectrum disorder (ortholog); Experimental Liver Neoplasms (ortholog); hypertension (ortholog); FOUND IN cytoplasm (ortholog); cytosol (ortholog); nucleus (ortholog)

Type:

protein-coding

RefSeq Status:

MODEL

Previously known as:

leukotriene B4 12-hydroxydehydrogenase; LTB4DH

RGD Orthologs

Alliance Orthologs

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	PTGR1 (prostaglandin reductase 1)	HGNC	EggNOG, Ensembl, Inparanoid, OMA, OrthoDB, OrthoMCL, Panther, Treefam
Mus musculus (house mouse):	Ptgr1 (prostaglandin reductase 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Rattus norvegicus (Norway rat):	Ptgr1 (prostaglandin reductase 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Ptgr1 (prostaglandin reductase 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	PTGR1 (prostaglandin reductase 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Ptgr1 (prostaglandin reductase 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	PTGR1 (prostaglandin reductase 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	LOC103219015 (prostaglandin reductase 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Ptgr1 (prostaglandin reductase 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline

Latest Assembly:

CanFam3.1 - Dog CanFam3.1 Assembly

Position:

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	11	66,191,155 - 66,212,075 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	11	66,191,165 - 66,209,219 (-)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	11	64,601,934 - 64,622,894 (-)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	11	67,324,103 - 67,345,145 (-)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	11	67,324,105 - 67,345,298 (-)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	11	65,841,533 - 65,862,116 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	11	65,864,869 - 65,885,860 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	11	66,554,733 - 66,575,785 (-)	NCBI		UU_Cfam_GSD_1.0

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Only show annotations with direct experimental evidence (0 objects hidden)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
PTGR1	Dog	Experimental Liver Neoplasms		ISO	RGD:621195	9068941	mRNA, protein:increased expression:liver	RGD	PMID:24853774\|REF_RGD_ID:14401713
PTGR1	Dog	hypertension		ISO	RGD:621195	9068941	mRNA:decreased expression:rostral ventrolateral medulla, paraventricular nucleus of hypothalamus, nucleus of solitary tract (rat)	RGD	PMID:23172924\|REF_RGD_ID:401959217

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
PTGR1	Dog	autism spectrum disorder		ISO	RGD:732819	9068941	CTD Direct Evidence: marker/mechanism	CTD	PMID:35663546

Biological Process

Only show annotations with direct experimental evidence (0 objects hidden)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
PTGR1	Dog	alkene metabolic process		ISO	RGD:621195	9068941		RGD	PMID:11524419\|REF_RGD_ID:38501077
PTGR1	Dog	fatty acid metabolic process	involved_in	IEA	UniProtKB-KW:KW-0276	150520179		UniProt	GO_REF:0000043
PTGR1	Dog	leukotriene B4 metabolic process	involved_in	ISO	RGD:13990213	9068941	PMID:8394361	UniProt	PMID:8394361
PTGR1	Dog	leukotriene B4 metabolic process		ISO	RGD:621195	9068941		RGD	PMID:9667737\|REF_RGD_ID:401959219
PTGR1	Dog	lipid metabolic process	involved_in	IEA	UniProtKB-KW:KW-0443	150520179		UniProt	GO_REF:0000043
PTGR1	Dog	lipoxin A4 metabolic process	involved_in	ISO	RGD:13990213	9068941	PMID:11688989	UniProt	PMID:11688989
PTGR1	Dog	negative regulation of positive chemotaxis		ISO	RGD:621195	9068941		RGD	PMID:9667737\|REF_RGD_ID:401959219
PTGR1	Dog	negative regulation of reactive oxygen species biosynthetic process		ISO	RGD:621195	9068941		RGD	PMID:9667737\|REF_RGD_ID:401959219
PTGR1	Dog	prostaglandin metabolic process	involved_in	IEA	UniProtKB-KW:KW-0644	150520179		UniProt	GO_REF:0000043
PTGR1	Dog	prostaglandin metabolic process	involved_in	IBA	PANTHER:PTN001707453\|UniProtKB:Q14914\|UniProtKB:Q8N8N7	150520179		GO_Central	GO_REF:0000033
PTGR1	Dog	prostaglandin metabolic process	involved_in	IEA	UniProtKB:Q14914\|ensembl:ENSP00000385763	150520179		Ensembl	GO_REF:0000107
PTGR1	Dog	response to antineoplastic agent		ISO	RGD:621195	9068941	1,2-dithiole-3-thione	RGD	PMID:8968041\|REF_RGD_ID:632607

Cellular Component

Only show annotations with direct experimental evidence (0 objects hidden)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
PTGR1	Dog	cytoplasm	located_in	IEA	InterPro:IPR014190	150520179		InterPro	GO_REF:0000002
PTGR1	Dog	cytoplasm	located_in	IEA	UniProtKB-SubCell:SL-0086	150520179		UniProt	GO_REF:0000044
PTGR1	Dog	cytoplasm		ISO	RGD:621195	9068941	ex vivo light microscopy with immunohistochemistry MMO:0000538	RGD	PMID:24853774\|REF_RGD_ID:14401713
PTGR1	Dog	cytosol		ISO	RGD:621195	9068941	cell fractionation MMO:0000679	RGD	PMID:9667737\|REF_RGD_ID:401959219
PTGR1	Dog	nucleus		ISO	RGD:621195	9068941	ex vivo light microscopy with immunohistochemistry MMO:0000538	RGD	PMID:24853774\|REF_RGD_ID:14401713

Molecular Function

Only show annotations with direct experimental evidence (0 objects hidden)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
PTGR1	Dog	13-lipoxin reductase activity	enables	ISO	RGD:13990213	9068941	PMID:11688989	UniProt	PMID:11688989
PTGR1	Dog	15-oxoprostaglandin 13-reductase [NAD(P)+] activity	enables	IEA	InterPro:IPR014190	150520179		InterPro	GO_REF:0000002
PTGR1	Dog	15-oxoprostaglandin 13-reductase [NAD(P)+] activity	enables	IBA	PANTHER:PTN001707453\|RGD:621195\|UniProtKB:Q14914\|UniProtKB:Q8N8N7	150520179		GO_Central	GO_REF:0000033
PTGR1	Dog	15-oxoprostaglandin 13-reductase [NAD(P)+] activity	enables	IEA	UniProtKB:Q14914\|ensembl:ENSP00000385763	150520179		Ensembl	GO_REF:0000107
PTGR1	Dog	2-alkenal reductase (NADPH) activity	enables	IEA	UniProtKB:Q14914\|ensembl:ENSP00000385763	150520179		Ensembl	GO_REF:0000107
PTGR1	Dog	2-alkenal reductase [NAD(P)H] activity	enables	IEA	InterPro:IPR014190	150520179		InterPro	GO_REF:0000002
PTGR1	Dog	leukotriene B4 12-hydroxy dehydrogenase activity	enables	ISO	RGD:13990213	9068941	PMID:8394361, PMID:8576264	UniProt	PMID:8394361\|PMID:8576264
PTGR1	Dog	oxidoreductase activity	enables	IEA	InterPro:IPR020843	150520179		InterPro	GO_REF:0000002
PTGR1	Dog	oxidoreductase activity	enables	IEA	UniProtKB-KW:KW-0560	150520179		UniProt	GO_REF:0000043
PTGR1	Dog	oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor	enables	IEA	InterPro:IPR045010	150520179		InterPro	GO_REF:0000002
PTGR1	Dog	protein binding	enables	ISO	UniProtKB:Q8WXH2	9068941	PMID:32814053	IntAct	PMID:32814053

PMID:22301074	PMID:30032202

PTGR1
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	11	66,191,155 - 66,212,075 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	11	66,191,165 - 66,209,219 (-)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	11	64,601,934 - 64,622,894 (-)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	11	67,324,103 - 67,345,145 (-)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	11	67,324,105 - 67,345,298 (-)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	11	65,841,533 - 65,862,116 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	11	65,864,869 - 65,885,860 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	11	66,554,733 - 66,575,785 (-)	NCBI		UU_Cfam_GSD_1.0

PTGR1
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	9	111,549,722 - 111,599,647 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	9	111,549,722 - 111,599,893 (-)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	9	114,312,002 - 114,361,927 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	9	113,365,073 - 113,401,532 (-)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	9	111,404,807 - 111,441,266	NCBI
Celera	9	84,811,079 - 84,861,206 (-)	NCBI		Celera
Cytogenetic Map	9	q31.3	NCBI
HuRef	9	83,911,040 - 83,960,627 (-)	NCBI		HuRef
CHM1_1	9	114,458,441 - 114,508,602 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	9	123,721,096 - 123,771,025 (-)	NCBI		T2T-CHM13v2.0

Ptgr1
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	4	58,965,590 - 58,987,131 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	4	58,965,439 - 58,987,119 (-)	Ensembl		GRCm39 Ensembl
GRCm38	4	58,965,590 - 58,987,131 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	4	58,965,439 - 58,987,119 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	4	58,978,462 - 58,999,950 (-)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	4	59,059,644 - 59,081,132 (-)	NCBI		MGSCv36	mm8
Celera	4	58,878,602 - 58,900,216 (-)	NCBI		Celera
Cytogenetic Map	4	B3	NCBI
cM Map	4	32.36	NCBI

Ptgr1
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	5	78,579,060 - 78,597,671 (-)	NCBI		GRCr8
mRatBN7.2	5	73,784,000 - 73,802,624 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	5	73,784,009 - 73,802,666 (-)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	5	75,685,300 - 75,703,919 (-)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	5	77,506,913 - 77,525,540 (-)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	5	77,479,071 - 77,497,693 (-)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	5	76,110,746 - 76,129,361 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	5	76,110,738 - 76,129,441 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	5	80,255,192 - 80,273,709 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	5	77,010,809 - 77,029,326 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	5	77,015,922 - 77,034,439 (-)	NCBI
Celera	5	72,607,043 - 72,625,264 (-)	NCBI		Celera
Cytogenetic Map	5	q24	NCBI

Ptgr1
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955419	15,708,456 - 15,739,147 (+)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955419	15,708,456 - 15,738,774 (+)	NCBI	ChiLan1.0	ChiLan1.0

PTGR1
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	11	27,816,183 - 27,860,132 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	9	27,824,016 - 27,862,494 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	9	82,700,541 - 82,739,024 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	9	110,862,122 - 110,900,829 (-)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	9	110,848,804 - 110,900,829 (-)	Ensembl	panpan1.1		panPan2

Ptgr1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024404947	181,503,868 - 181,535,213 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936559	1,731,533 - 1,762,671 (+)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936559	1,731,346 - 1,762,676 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

PTGR1
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	1	252,373,282 - 252,395,948 (-)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	1	252,373,272 - 252,395,948 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	1	283,170,868 - 283,177,809 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

LOC103219015
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	12	27,918,990 - 27,999,736 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
Vero_WHO_p1.0	NW_023666035	14,779,257 - 14,799,467 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Ptgr1
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla 1.0	NW_004624760	23,406,085 - 23,433,283 (+)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Variants in PTGR1
473 total Variants

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

adipose tissue	alimentary part of gastrointestinal system	circulatory system	ectoderm	endocrine system	endoderm	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	mesenchyme	mesoderm	nervous system	reproductive system	respiratory system
6	5	5	23	22	16	6	6	6	6	33	22	12	14	10


RefSeq Transcripts	XM_005626921	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_005626922	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_014117918	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038490965	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038553104	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038553105	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038616979	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038616980	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038653902	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038682439	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038682440	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AAEX04000011	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAAHUQ010000119	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAAQRD010000003	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAAUVH010000356	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	REHQ01000011	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSCAFT00000004823 ⟹ ENSCAFP00000004469

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
CanFam3.1 Ensembl	11	66,191,165 - 66,209,219 (-)	Ensembl

Ensembl Acc Id:

ENSCAFT00000079878 ⟹ ENSCAFP00000050830

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
CanFam3.1 Ensembl	11	66,191,165 - 66,207,757 (-)	Ensembl

Ensembl Acc Id:

ENSCAFT00845009852 ⟹ ENSCAFP00845007696

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
ROS_Cfam_1.0 Ensembl	11	67,324,105 - 67,343,752 (-)	Ensembl

Ensembl Acc Id:

ENSCAFT00845009862 ⟹ ENSCAFP00845007701

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
ROS_Cfam_1.0 Ensembl	11	67,339,274 - 67,345,298 (-)	Ensembl

RefSeq Acc Id:

XM_005626922 ⟹ XP_005626979

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
CanFam3.1	11	66,191,155 - 66,210,860 (-)	NCBI
Dog10K_Boxer_Tasha	11	64,601,934 - 64,621,640 (-)	NCBI

Sequence:

show sequence

GCCCTAGGTGGGCGGAGCCCGGGTCCTGGGGGATGGAGGCCTCGGGGTGACTCCAGTCTGCGGGGGTCCAGGGCCCCGGTGCCCGCCCGCGAGCGGCGGAGGTCAGCCTTCGCTTTGAAACAGCGAGG
TTGGGAAGCAAAGGAGTCCGATCACCGATTCGTGGCCTCTGTTTTGCTTGGGCTGTGCCCAGGCCAGGCAAAGACGAACTTCAAGATGGTTCATGCTAAGAGCTGGACTCTGAAGAAGCACTTTGAAG
GCAGCCCTACTCATAGTAACTTTGAGTTAAAGACGGTTGAACTCCCGTCCTTAAAAAATGGAGAGGTCCTGCTGGAAGCTTTGTTCCTTACCGTGGATCCTTACATGAGAGTGGCAGCCAAAAGATTG
AAGGAGGGTGACATGATGATGGGGCAGCAAGTGGCCAGAGTTGTGGAAAGTAAAAACTCAGCCTTCCCAGCAGGAACTGTGGTAGTGGCTTCTTCAGGCTGGACATCACACTCTATTTCTGATGGGAA
AGATCTGGAAAAGCTGCCTGCAGAGTGGCCAGACACCGTACCAGTGTCTTTGGCTTTGGGAACAATTGGCATGACAGGACTAACAGCCTACTTTGGCCTCCTTGACATCTGTGGTGTGAAGGGTGGAG
AAACAGTGATGGTTAATGCAGCAGCAGGGGCAGTGGGCTCTGTGGTGGGGCAGATTGCTAAGCTCAAGGGCTGCAAAGTTGTTGGAGCAGCAGGGTCTGACGAAAAGGTTGCCTACCTTAAAAAGCTT
GGATATGATGTTGCCTTTAACTACAAAACCATAAAGTCTTTGGAAGAAACTTTGAAAAAAGCCTCTCCTGATGGTTATGATTGTTACTTTGATAATGTAGGTGGAGAGTTTTCAAACATTGTTATTCC
CCAGATGAAGAAGTTTGGAAGAATTGCTATTTGTGGGGCCATCTCGACATATAATAGTACTCGCCCACTTCCCCCAGGCCCACCCCCGGAGAATATTATCTATCAGCAGCTCCGCATGGAAGGGTTCA
TCGTTAATCGCTGGCAAGGAGATGTCCGCCAGAAGGCTCTGAAAGACTTGCTGACATGGGTCATAGAGGGTAAAATCCAGTACCACGAATACATCATTGAAGGATTTGAAAACATGCCGGCTGCATTT
ATGGGAATGCTGAAAGGAGATAATTTGGGAAAAACAATAGTGAAAGCATGAAAAAAATGACACATGGAATCTAGAAATCATTTGGATGATGACTTAATTTCTTTTTAACCATTTAATAAAAAATGTAT
ACTACCTTCATTA

hide sequence

RefSeq Acc Id:

XM_038490965 ⟹ XP_038346893

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
UMICH_Zoey_3.1	11	65,841,533 - 65,862,116 (-)	NCBI

RefSeq Acc Id:

XM_038553104 ⟹ XP_038409032

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
UU_Cfam_GSD_1.0	11	66,554,733 - 66,575,785 (-)	NCBI

RefSeq Acc Id:

XM_038553105 ⟹ XP_038409033

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
UU_Cfam_GSD_1.0	11	66,554,733 - 66,574,420 (-)	NCBI

RefSeq Acc Id:

XM_038616979 ⟹ XP_038472907

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
UNSW_CanFamBas_1.0	11	65,864,869 - 65,885,860 (-)	NCBI

RefSeq Acc Id:

XM_038616980 ⟹ XP_038472908

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
UNSW_CanFamBas_1.0	11	65,864,869 - 65,884,516 (-)	NCBI

RefSeq Acc Id:

XM_038653902 ⟹ XP_038509830

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
Dog10K_Boxer_Tasha	11	64,601,934 - 64,622,894 (-)	NCBI

RefSeq Acc Id:

XM_038682439 ⟹ XP_038538367

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
ROS_Cfam_1.0	11	67,324,103 - 67,345,145 (-)	NCBI

RefSeq Acc Id:

XM_038682440 ⟹ XP_038538368

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
ROS_Cfam_1.0	11	67,324,103 - 67,343,777 (-)	NCBI


Protein RefSeqs	XP_005626979	(Get FASTA)	NCBI Sequence Viewer
	XP_038346893	(Get FASTA)	NCBI Sequence Viewer
	XP_038409032	(Get FASTA)	NCBI Sequence Viewer
	XP_038409033	(Get FASTA)	NCBI Sequence Viewer
	XP_038472907	(Get FASTA)	NCBI Sequence Viewer
	XP_038472908	(Get FASTA)	NCBI Sequence Viewer
	XP_038509830	(Get FASTA)	NCBI Sequence Viewer
	XP_038538367	(Get FASTA)	NCBI Sequence Viewer
	XP_038538368	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSCAFP00000004469.3
	ENSCAFP00000074520.1
	ENSCAFP00030013623.1
	ENSCAFP00030013693.1
	ENSCAFP00845007696
	ENSCAFP00845007696.1
	ENSCAFP00845007701.1

RefSeq Acc Id:

XP_005626979 ⟸ XM_005626922

- UniProtKB:

A0A8C0MR59 (UniProtKB/TrEMBL), A0A8I3MRC0 (UniProtKB/TrEMBL), A0A8C0MZC4 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MVHAKSWTLKKHFEGSPTHSNFELKTVELPSLKNGEVLLEALFLTVDPYMRVAAKRLKEGDMMMGQQVARVVESKNSAFPAGTVVVASSGWTSHSISDGKDLEKLPAEWPDTVPVSLALGTIGMTGLT
AYFGLLDICGVKGGETVMVNAAAGAVGSVVGQIAKLKGCKVVGAAGSDEKVAYLKKLGYDVAFNYKTIKSLEETLKKASPDGYDCYFDNVGGEFSNIVIPQMKKFGRIAICGAISTYNSTRPLPPGPP
PENIIYQQLRMEGFIVNRWQGDVRQKALKDLLTWVIEGKIQYHEYIIEGFENMPAAFMGMLKGDNLGKTIVKA

hide sequence

Ensembl Acc Id:

ENSCAFP00000004469 ⟸ ENSCAFT00000004823

Ensembl Acc Id:

ENSCAFP00000050830 ⟸ ENSCAFT00000079878

RefSeq Acc Id:

XP_038346893 ⟸ XM_038490965

RefSeq Acc Id:

XP_038472907 ⟸ XM_038616979

Protein Domains

Enoyl reductase (ER) Oxidoreductase N-terminal

RGD ID:

13685299

Promoter ID:

EPDNEW_C3367

Type:

single initiation site

Name:

PTGR1_1

Description:

prostaglandin reductase 1

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Experiment Methods:

Single-end sequencing.

Position:

Dog Assembly	Chr	Position (strand)	Source
CanFam3.1	11	66,209,222 - 66,209,282	EPDNEW

Database	Acc Id	Source(s)
Ensembl Genes	ENSCAFG00000003000	Ensembl, UniProtKB/TrEMBL
	ENSCAFG00030008504	UniProtKB/TrEMBL
	ENSCAFG00845005537	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSCAFT00000004823.5	UniProtKB/TrEMBL
	ENSCAFT00000110192.1	UniProtKB/TrEMBL
	ENSCAFT00030015631.1	UniProtKB/TrEMBL
	ENSCAFT00030015706.1	UniProtKB/TrEMBL
	ENSCAFT00845009852	ENTREZGENE
	ENSCAFT00845009852.1	UniProtKB/TrEMBL
	ENSCAFT00845009862.1	UniProtKB/TrEMBL
Gene3D-CATH	Medium-chain alcohol dehydrogenases, catalytic domain	UniProtKB/TrEMBL
	NAD(P)-binding Rossmann-like Domain	UniProtKB/TrEMBL
InterPro	ADH_C	UniProtKB/TrEMBL
	ADH_N_2	UniProtKB/TrEMBL
	GroES-like_sf	UniProtKB/TrEMBL
	MDR_fam	UniProtKB/TrEMBL
	NAD(P)-bd_dom_sf	UniProtKB/TrEMBL
	PKS_ER	UniProtKB/TrEMBL
	PTGR1	UniProtKB/TrEMBL
KEGG Report	cfa:474802	UniProtKB/TrEMBL
NCBI Gene	PTGR1	ENTREZGENE
PANTHER	PROSTAGLANDIN REDUCTASE 1	UniProtKB/TrEMBL
	PTHR43205	UniProtKB/TrEMBL
Pfam	ADH_N_2	UniProtKB/TrEMBL
	ADH_zinc_N	UniProtKB/TrEMBL
SMART	PKS_ER	UniProtKB/TrEMBL
Superfamily-SCOP	SSF50129	UniProtKB/TrEMBL
	SSF51735	UniProtKB/TrEMBL
UniProt	A0A8C0MR59	ENTREZGENE, UniProtKB/TrEMBL
	A0A8C0MZC4	ENTREZGENE, UniProtKB/TrEMBL
	A0A8I3MRC0	ENTREZGENE, UniProtKB/TrEMBL
	A0A8I3RSQ9_CANLF	UniProtKB/TrEMBL
	A0A8P0TTA0_CANLF	UniProtKB/TrEMBL
VGNC ID	VGNC:45150	ENTREZGENE

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailable


InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailable


Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
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MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable

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Imported Disease Annotations - CTD