CIART (circadian associated repressor of transcription) - Rat Genome Database

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Gene: CIART (circadian associated repressor of transcription) Canis lupus familiaris
Analyze
Symbol: CIART
Name: circadian associated repressor of transcription
RGD ID: 12142127
Description: ENCODES a protein that exhibits E-box binding (inferred); RNA polymerase II cis-regulatory region sequence-specific DNA binding (inferred); transcription cis-regulatory region binding (inferred); INVOLVED IN circadian regulation of gene expression (inferred); locomotor rhythm (inferred); negative regulation of DNA-templated transcription (inferred); ASSOCIATED WITH gastrointestinal stromal tumor (ortholog); immunodeficiency 42 (ortholog); MHC class II deficiency (ortholog); FOUND IN nucleus (inferred); INTERACTS WITH bisphenol A
Type: protein-coding
RefSeq Status: MODEL
Previously known as: circadian-associated transcriptional repressor
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: CanFam3.1 - Dog CanFam3.1 Assembly
Position:
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11759,524,715 - 59,529,535 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1759,525,987 - 59,529,402 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1758,971,251 - 58,975,921 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01760,540,474 - 60,545,124 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1760,532,582 - 60,545,108 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11759,370,942 - 59,375,587 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01759,454,744 - 59,459,367 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01760,182,501 - 60,187,143 (+)NCBIUU_Cfam_GSD_1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
CIARTDoggastrointestinal stromal tumor  ISORGD:13478168554872ClinVar Annotator: match by term: Gastrointestinal stromal tumorClinVarPMID:28492532
CIARTDogimmunodeficiency 42  ISORGD:13478168554872ClinVar Annotator: match by term: Autosomal recessive mendelian susceptibility to mycobacterial diseases due to complete more ...ClinVarPMID:28492532
CIARTDogMHC class II deficiency  ISORGD:13478168554872ClinVar Annotator: match by term: MHC class II deficiencyClinVarPMID:28492532
CIARTDogparathyroid carcinoma  ISORGD:13478168554872ClinVar Annotator: match by term: Parathyroid carcinomaClinVarPMID:28492532
CIARTDogsevere congenital neutropenia 3  ISORGD:13478168554872ClinVar Annotator: match by term: Kostmann syndromeClinVarPMID:28492532
CIARTDogsevere congenital neutropenia 5  ISORGD:13478168554872ClinVar Annotator: match by term: Congenital neutropenia-myelofibrosis-nephromegaly syndromeClinVarPMID:28492532


  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
CIARTDogbisphenol A increases expressionEXP 6480464bisphenol A results in increased expression of CIART mRNACTDPMID:38866337


Biological Process

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
CIARTDogcircadian regulation of gene expression involved_inIEAInterPro:IPR031373150520179 InterProGO_REF:0000002
CIARTDogcircadian regulation of gene expression involved_inIBAMGI:2684975|PANTHER:PTN002860200150520179 GO_CentralGO_REF:0000033
CIARTDogcircadian regulation of gene expression involved_inIEAUniProtKB:Q3TQ03|ensembl:ENSMUSP00000124943150520179 EnsemblGO_REF:0000107
CIARTDoglocomotor rhythm involved_inIEAUniProtKB:Q3TQ03|ensembl:ENSMUSP00000124943150520179 EnsemblGO_REF:0000107
CIARTDognegative regulation of DNA-templated transcription involved_inIBAMGI:2684975|PANTHER:PTN002860200150520179 GO_CentralGO_REF:0000033
CIARTDognegative regulation of DNA-templated transcription involved_inIEAUniProtKB:Q3TQ03|ensembl:ENSMUSP00000124943150520179 EnsemblGO_REF:0000107

Cellular Component

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
CIARTDognucleus located_inIEAUniProtKB:Q3TQ03|ensembl:ENSMUSP00000124943150520179 EnsemblGO_REF:0000107
CIARTDognucleus is_active_inIBAMGI:2684975|PANTHER:PTN002860200150520179 GO_CentralGO_REF:0000033

Molecular Function
1 to 12 of 12 rows

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
CIARTDogE-box binding enablesIEAUniProtKB:Q3TQ03|ensembl:ENSMUSP00000124943150520179 EnsemblGO_REF:0000107
CIARTDogprotein binding enablesISOUniProtKB:O09106|UniProtKB:O54943|UniProtKB:P06537|UniProtKB:Q99PV5|UniProtKB:Q9R194|UniProtKB:Q9WTL89068941 PMID:24736997UniProtPMID:24736997
CIARTDogprotein binding enablesISOUniProtKB:O54943|UniProtKB:Q9WTL89068941 PMID:24385426UniProtPMID:24385426
CIARTDogprotein binding enablesISOUniProtKB:O09106|UniProtKB:O54943|UniProtKB:Q99PV5|UniProtKB:Q9R194|UniProtKB:Q9WTL89068941 PMID:24736997IntActPMID:24736997
CIARTDogprotein binding enablesISOUniProtKB:O54943|UniProtKB:Q9WTL89068941 PMID:24737000IntActPMID:24737000
CIARTDogprotein binding enablesISOUniProtKB:P13473-2|UniProtKB:P552129068941 PMID:32814053IntActPMID:32814053
CIARTDogprotein binding enablesISOUniProtKB:O003279068941 PMID:24385426UniProtPMID:24385426
CIARTDogprotein binding enablesISOUniProtKB:O755539068941 PMID:25416956IntActPMID:25416956
CIARTDogprotein binding enablesISOUniProtKB:Q13952-29068941 PMID:32296183IntActPMID:32296183
CIARTDogRNA polymerase II cis-regulatory region sequence-specific DNA binding enablesIEAUniProtKB:Q3TQ03|ensembl:ENSMUSP00000124943150520179 EnsemblGO_REF:0000107
CIARTDogRNA polymerase II cis-regulatory region sequence-specific DNA binding enablesIBAMGI:2684975|PANTHER:PTN002860200150520179 GO_CentralGO_REF:0000033
CIARTDogtranscription cis-regulatory region binding enablesIEAInterPro:IPR031373150520179 InterProGO_REF:0000002
1 to 12 of 12 rows

PMID:22301074   PMID:30032202  



CIART
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11759,524,715 - 59,529,535 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1759,525,987 - 59,529,402 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1758,971,251 - 58,975,921 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01760,540,474 - 60,545,124 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1760,532,582 - 60,545,108 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11759,370,942 - 59,375,587 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01759,454,744 - 59,459,367 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01760,182,501 - 60,187,143 (+)NCBIUU_Cfam_GSD_1.0
CIART
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381150,282,554 - 150,287,093 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1150,282,543 - 150,287,093 (+)EnsemblGRCh38hg38GRCh38
GRCh371150,254,964 - 150,259,505 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361148,521,853 - 148,526,125 (+)NCBINCBI36Build 36hg18NCBI36
Build 341147,068,301 - 147,072,574NCBI
Celera1123,370,960 - 123,375,233 (+)NCBICelera
Cytogenetic Map1q21.2NCBI
HuRef1121,633,885 - 121,638,163 (+)NCBIHuRef
CHM1_11151,650,945 - 151,655,215 (+)NCBICHM1_1
T2T-CHM13v2.01149,407,478 - 149,412,040 (+)NCBIT2T-CHM13v2.0
Ciart
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39395,785,812 - 95,790,012 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl395,785,815 - 95,789,563 (-)EnsemblGRCm39 Ensembl
GRCm38395,878,500 - 95,882,257 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl395,878,503 - 95,882,251 (-)EnsemblGRCm38mm10GRCm38
MGSCv37395,682,428 - 95,686,151 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36395,963,908 - 95,967,633 (-)NCBIMGSCv36mm8
Celera397,312,032 - 97,315,756 (-)NCBICelera
Cytogenetic Map3F2.1NCBI
cM Map341.42NCBI
Ciart
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr82186,108,744 - 186,113,778 (-)NCBIGRCr8
mRatBN7.22183,419,819 - 183,424,845 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl2183,419,819 - 183,423,313 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx2191,084,561 - 191,088,055 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.02188,888,111 - 188,891,608 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.02183,717,098 - 183,720,592 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.02197,987,705 - 197,991,198 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl2197,987,705 - 197,991,574 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.02217,478,839 - 217,482,049 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.42190,659,555 - 190,663,895 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera2175,949,238 - 175,952,732 (-)NCBICelera
Cytogenetic Map2q34NCBI
Ciart
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0NW_004955413490,117 - 494,332 (-)NCBIChiLan1.0ChiLan1.0
CIART
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2199,551,579 - 99,556,149 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1199,305,525 - 99,310,122 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01125,627,812 - 125,632,367 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11129,278,742 - 129,283,271 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1129,278,742 - 129,283,271 (+)Ensemblpanpan1.1panPan2
Ciart
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440505821,536,328 - 21,540,785 (+)NCBIHiC_Itri_2
SpeTri2.0NW_004936580566,745 - 571,160 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
CIART
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl498,800,931 - 98,804,739 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1498,800,849 - 98,809,573 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.24108,088,573 - 108,093,770 (-)NCBISscrofa10.2Sscrofa10.2susScr3
CIART
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Vero_WHO_p1.0NW_02366603813,005,562 - 13,010,479 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Ciart
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462477218,037,066 - 18,040,692 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462477218,036,407 - 18,040,571 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

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Variants in CIART
47 total Variants



adipose tissue
alimentary part of gastrointestinal system
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
reproductive system
respiratory system
6 5 5 23 22 16 6 6 6 6 33 22 12 14 10


1 to 20 of 20 rows
RefSeq Transcripts XM_003639643 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_005630746 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038423035 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038423036 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038423037 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038453077 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038499534 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038499535 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038499536 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038562106 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038562107 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038562108 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038626202 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038626203 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038626204 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AAEX04000017 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAAHUQ010000209 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAAQRD010000035 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAAUVH010000359 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  REHQ01000017 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
1 to 20 of 20 rows

Ensembl Acc Id: ENSCAFT00000018735   ⟹   ENSCAFP00000017357
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl1759,525,987 - 59,529,402 (+)Ensembl
Ensembl Acc Id: ENSCAFT00845029874   ⟹   ENSCAFP00845023461
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl1760,532,582 - 60,545,108 (+)Ensembl
RefSeq Acc Id: XM_003639643   ⟹   XP_003639691
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.11759,524,715 - 59,529,535 (+)NCBI
Dog10K_Boxer_Tasha1758,971,251 - 58,975,921 (+)NCBI
Sequence:
RefSeq Acc Id: XM_005630746   ⟹   XP_005630803
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.11759,525,270 - 59,529,535 (+)NCBI
Dog10K_Boxer_Tasha1758,971,615 - 58,975,921 (+)NCBI
Sequence:
RefSeq Acc Id: XM_038423035   ⟹   XP_038278963
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.01760,540,838 - 60,545,124 (+)NCBI
RefSeq Acc Id: XM_038423036   ⟹   XP_038278964
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.01760,540,474 - 60,545,124 (+)NCBI
RefSeq Acc Id: XM_038423037   ⟹   XP_038278965
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.01760,540,990 - 60,545,124 (+)NCBI
RefSeq Acc Id: XM_038453077   ⟹   XP_038309005
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
Dog10K_Boxer_Tasha1758,971,767 - 58,975,921 (+)NCBI
RefSeq Acc Id: XM_038499534   ⟹   XP_038355462
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.11759,371,306 - 59,375,587 (+)NCBI
RefSeq Acc Id: XM_038499535   ⟹   XP_038355463
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.11759,370,942 - 59,375,587 (+)NCBI
RefSeq Acc Id: XM_038499536   ⟹   XP_038355464
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.11759,371,458 - 59,375,587 (+)NCBI
RefSeq Acc Id: XM_038562106   ⟹   XP_038418034
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.01760,182,865 - 60,187,143 (+)NCBI
RefSeq Acc Id: XM_038562107   ⟹   XP_038418035
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.01760,182,501 - 60,187,143 (+)NCBI
RefSeq Acc Id: XM_038562108   ⟹   XP_038418036
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.01760,183,017 - 60,187,143 (+)NCBI
RefSeq Acc Id: XM_038626202   ⟹   XP_038482130
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.01759,455,108 - 59,459,367 (+)NCBI
RefSeq Acc Id: XM_038626203   ⟹   XP_038482131
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.01759,454,744 - 59,459,367 (+)NCBI
RefSeq Acc Id: XM_038626204   ⟹   XP_038482132
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.01759,455,260 - 59,459,367 (+)NCBI
1 to 5 of 17 rows
1 to 5 of 17 rows
RefSeq Acc Id: XP_003639691   ⟸   XM_003639643
- UniProtKB: A0A8C0L5M9 (UniProtKB/TrEMBL),   A0A8C0ME62 (UniProtKB/TrEMBL),   A0A8I3P2Z3 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_005630803   ⟸   XM_005630746
- UniProtKB: A0A8C0L5M9 (UniProtKB/TrEMBL),   A0A8C0ME62 (UniProtKB/TrEMBL),   A0A8I3P2Z3 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSCAFP00000017357   ⟸   ENSCAFT00000018735
RefSeq Acc Id: XP_038355463   ⟸   XM_038499535
RefSeq Acc Id: XP_038355462   ⟸   XM_038499534



1 to 19 of 19 rows
Database
Acc Id
Source(s)
Ensembl Genes ENSCAFG00000011804 Ensembl, UniProtKB/TrEMBL
  ENSCAFG00030005497 UniProtKB/TrEMBL
  ENSCAFG00040010085 UniProtKB/TrEMBL
  ENSCAFG00845016855 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCAFT00000018735.5 UniProtKB/TrEMBL
  ENSCAFT00030010113.1 UniProtKB/TrEMBL
  ENSCAFT00040018753.1 UniProtKB/TrEMBL
  ENSCAFT00845029874 ENTREZGENE
  ENSCAFT00845029874.1 UniProtKB/TrEMBL
InterPro Ciart UniProtKB/TrEMBL
KEGG Report cfa:100856543 UniProtKB/TrEMBL
NCBI Gene CIART ENTREZGENE
PANTHER CIRCADIAN-ASSOCIATED TRANSCRIPTIONAL REPRESSOR UniProtKB/TrEMBL
  PTHR35441 UniProtKB/TrEMBL
Pfam Ciart UniProtKB/TrEMBL
UniProt A0A8C0L5M9 ENTREZGENE
  A0A8C0ME62 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I3P2Z3 ENTREZGENE, UniProtKB/TrEMBL
VGNC ID VGNC:39265 ENTREZGENE
1 to 19 of 19 rows