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Gene: SCGN (secretagogin, EF-hand calcium binding protein) Canis lupus familiaris

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Symbol:

SCGN

Name:

secretagogin, EF-hand calcium binding protein

RGD ID:

12136391

Description:

ENCODES a protein that exhibits calcium ion binding (inferred); metal ion binding (inferred); FOUND IN transport vesicle membrane (inferred)

Type:

protein-coding

RefSeq Status:

MODEL

Previously known as:

secretagogin

RGD Orthologs

Alliance Orthologs

More Info

more info ...

Latest Assembly:

CanFam3.1 - Dog CanFam3.1 Assembly

Position:

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	35	23,602,244 - 23,638,108 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	35	23,602,343 - 23,638,055 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	35	23,531,684 - 23,540,559 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	35	23,717,908 - 23,753,767 (+)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	35	23,717,868 - 23,753,765 (+)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	35	23,527,247 - 23,563,304 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	35	23,577,972 - 23,614,023 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	35	25,015,623 - 25,051,501 (+)	NCBI		UU_Cfam_GSD_1.0

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Cellular Component

Only show annotations with direct experimental evidence (0 objects hidden)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
SCGN	Dog	cytosol	is_active_in	IBA	MGI:88248\|PANTHER:PTN001461922\|RGD:69340\|UniProtKB:P22676	150520179		GO_Central	GO_REF:0000033
SCGN	Dog	dendrite	is_active_in	IBA	MGI:88248\|PANTHER:PTN000463232\|UniProtKB:P05937	150520179		GO_Central	GO_REF:0000033
SCGN	Dog	nucleus	is_active_in	IBA	MGI:88248\|PANTHER:PTN001461922\|UniProtKB:P05937	150520179		GO_Central	GO_REF:0000033
SCGN	Dog	synapse	is_active_in	IBA	FB:FBgn0004580\|MGI:101914\|MGI:88248\|PANTHER:PTN001461922\|RGD:620981\|RGD:69340\|UniProtKB:P04354	150520179		GO_Central	GO_REF:0000033
SCGN	Dog	terminal bouton	is_active_in	IBA	FB:FBgn0004580\|PANTHER:PTN000463232	150520179		GO_Central	GO_REF:0000033
SCGN	Dog	transport vesicle membrane	located_in	IEA	UniProtKB-SubCell:SL-0245	150520179		UniProt	GO_REF:0000044

Molecular Function

Only show annotations with direct experimental evidence (0 objects hidden)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
SCGN	Dog	calcium ion binding	enables	IBA	MGI:101914\|MGI:88248\|PANTHER:PTN001461922\|RGD:620981\|RGD:69340\|UniProtKB:P05937	150520179		GO_Central	GO_REF:0000033
SCGN	Dog	calcium ion binding	enables	IEA	InterPro:IPR002048	150520179		InterPro	GO_REF:0000002
SCGN	Dog	metal ion binding	enables	IEA	UniProtKB-KW:KW-0479	150520179		UniProt	GO_REF:0000043
SCGN	Dog	protein binding	enables	ISO	UniProtKB:Q9NYB9-2	9068941	PMID:32296183	IntAct	PMID:32296183
SCGN	Dog	protein binding	enables	ISO	UniProtKB:O00161	9068941	PMID:16189514, PMID:33961781	IntAct	PMID:16189514\|PMID:33961781

PMID:22301074	PMID:30032202

SCGN
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	35	23,602,244 - 23,638,108 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	35	23,602,343 - 23,638,055 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	35	23,531,684 - 23,540,559 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	35	23,717,908 - 23,753,767 (+)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	35	23,717,868 - 23,753,765 (+)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	35	23,527,247 - 23,563,304 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	35	23,577,972 - 23,614,023 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	35	25,015,623 - 25,051,501 (+)	NCBI		UU_Cfam_GSD_1.0

SCGN
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	6	25,652,215 - 25,701,783 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	6	25,652,201 - 25,701,783 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	6	25,652,443 - 25,702,011 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	6	25,760,408 - 25,809,990 (+)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	6	25,760,407 - 25,809,985	NCBI
Celera	6	26,879,633 - 26,929,216 (+)	NCBI		Celera
Cytogenetic Map	6	p22.2	NCBI
HuRef	6	25,595,416 - 25,644,987 (+)	NCBI		HuRef
CHM1_1	6	25,654,627 - 25,704,213 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	6	25,518,025 - 25,567,550 (+)	NCBI		T2T-CHM13v2.0

Scgn
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	13	24,137,439 - 24,175,310 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	13	24,137,439 - 24,175,197 (-)	Ensembl		GRCm39 Ensembl
GRCm38	13	23,953,456 - 23,991,327 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	13	23,953,456 - 23,991,214 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	13	24,045,325 - 24,083,083 (-)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	13	23,960,921 - 23,998,679 (-)	NCBI		MGSCv36	mm8
Celera	13	24,185,142 - 24,222,913 (-)	NCBI		Celera
Cytogenetic Map	13	A3.1	NCBI
cM Map	13	10.01	NCBI

Scgn
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	17	41,534,558 - 41,576,525 (+)	NCBI		GRCr8
mRatBN7.2	17	41,106,681 - 41,148,656 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	17	41,106,467 - 41,148,667 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	17	41,174,261 - 41,215,631 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	17	42,778,305 - 42,819,675 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	17	41,062,609 - 41,103,976 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	17	43,357,888 - 43,399,321 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	17	43,357,888 - 43,399,321 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	17	45,214,579 - 45,256,809 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	17	48,225,075 - 48,266,508 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	17	48,227,915 - 48,269,349 (+)	NCBI
Celera	17	40,739,598 - 40,779,916 (+)	NCBI		Celera
Cytogenetic Map	17	p11	NCBI

Scgn
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955483	1,392,770 - 1,429,594 (-)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955483	1,392,772 - 1,429,563 (-)	NCBI	ChiLan1.0	ChiLan1.0

SCGN
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	5	40,299,097 - 40,367,239 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	6	36,300,454 - 36,350,030 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	6	25,486,599 - 25,571,272 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	6	25,812,650 - 25,862,236 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	6	25,812,443 - 25,862,227 (+)	Ensembl	panpan1.1		panPan2

Scgn
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024404946	1,929,640 - 1,965,364 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936671	1,655,978 - 1,693,175 (+)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936671	1,656,179 - 1,696,580 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

SCGN
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	7	20,389,493 - 20,432,978 (+)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	7	20,389,156 - 20,432,985 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	7	21,689,440 - 21,732,931 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

SCGN
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	17	46,554,759 - 46,605,282 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	17	46,565,302 - 46,604,710 (-)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666044	25,585,367 - 25,635,700 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Scgn
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624756	1,368,434 - 1,407,885 (-)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624756	1,368,330 - 1,407,914 (-)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Variants in SCGN
463 total Variants

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

adipose tissue	alimentary part of gastrointestinal system	circulatory system	ectoderm	endocrine system	endoderm	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	mesenchyme	mesoderm	nervous system	reproductive system	respiratory system
3	5	2	20	17	9	1	1	1	3	16	10	12	9	8


RefSeq Transcripts	XM_022414565	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038446183	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038446184	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038463103	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038520834	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038520835	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038583964	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038583965	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038648382	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038648383	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_848547	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AAEX04000035	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAAHUQ010000351	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAAQRD010000081	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAAUVH010000369	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	REHQ01000035	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSCAFT00000016776 ⟹ ENSCAFP00000015524

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
CanFam3.1 Ensembl	35	23,602,343 - 23,638,055 (+)	Ensembl

Ensembl Acc Id:

ENSCAFT00845042762 ⟹ ENSCAFP00845033523

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
ROS_Cfam_1.0 Ensembl	35	23,717,868 - 23,753,765 (+)	Ensembl

RefSeq Acc Id:

XM_038446183 ⟹ XP_038302111

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
ROS_Cfam_1.0	35	23,717,912 - 23,753,767 (+)	NCBI

RefSeq Acc Id:

XM_038446184 ⟹ XP_038302112

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
ROS_Cfam_1.0	35	23,717,908 - 23,753,767 (+)	NCBI

RefSeq Acc Id:

XM_038463103 ⟹ XP_038319031

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
Dog10K_Boxer_Tasha	35	23,531,684 - 23,540,559 (+)	NCBI

RefSeq Acc Id:

XM_038520834 ⟹ XP_038376762

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
UMICH_Zoey_3.1	35	23,527,247 - 23,563,304 (+)	NCBI

RefSeq Acc Id:

XM_038520835 ⟹ XP_038376763

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
UMICH_Zoey_3.1	35	23,527,247 - 23,563,304 (+)	NCBI

RefSeq Acc Id:

XM_038583964 ⟹ XP_038439892

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
UU_Cfam_GSD_1.0	35	25,015,625 - 25,051,501 (+)	NCBI

RefSeq Acc Id:

XM_038583965 ⟹ XP_038439893

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
UU_Cfam_GSD_1.0	35	25,015,623 - 25,051,501 (+)	NCBI

RefSeq Acc Id:

XM_038648382 ⟹ XP_038504310

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
UNSW_CanFamBas_1.0	35	23,577,972 - 23,614,023 (+)	NCBI

RefSeq Acc Id:

XM_038648383 ⟹ XP_038504311

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
UNSW_CanFamBas_1.0	35	23,577,972 - 23,614,023 (+)	NCBI


Protein RefSeqs	XP_038302111	(Get FASTA)	NCBI Sequence Viewer
	XP_038302112	(Get FASTA)	NCBI Sequence Viewer
	XP_038319031	(Get FASTA)	NCBI Sequence Viewer
	XP_038376762	(Get FASTA)	NCBI Sequence Viewer
	XP_038376763	(Get FASTA)	NCBI Sequence Viewer
	XP_038439892	(Get FASTA)	NCBI Sequence Viewer
	XP_038439893	(Get FASTA)	NCBI Sequence Viewer
	XP_038504310	(Get FASTA)	NCBI Sequence Viewer
	XP_038504311	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSCAFP00000015524.4
	ENSCAFP00030033726.1
	ENSCAFP00040039934.1
	ENSCAFP00040039948.1
	ENSCAFP00845033523
	ENSCAFP00845033523.1

Ensembl Acc Id:

ENSCAFP00000015524 ⟸ ENSCAFT00000016776

RefSeq Acc Id:	XP_038376762 ⟸ XM_038520834
- Peptide Label:	isoform X1

RefSeq Acc Id:	XP_038376763 ⟸ XM_038520835
- Peptide Label:	isoform X2

RefSeq Acc Id:	XP_038504310 ⟸ XM_038648382
- Peptide Label:	isoform X1

RefSeq Acc Id:	XP_038504311 ⟸ XM_038648383
- Peptide Label:	isoform X2

Protein Domains

EF-hand

Database	Acc Id	Source(s)
Ensembl Genes	ENSCAFG00000010559	Ensembl, UniProtKB/TrEMBL
	ENSCAFG00030021047	UniProtKB/TrEMBL
	ENSCAFG00040024574	UniProtKB/TrEMBL
	ENSCAFG00845024214	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSCAFT00000016776.5	UniProtKB/TrEMBL
	ENSCAFT00030038649.1	UniProtKB/TrEMBL
	ENSCAFT00040045748.1	UniProtKB/TrEMBL
	ENSCAFT00040045764.1	UniProtKB/TrEMBL
	ENSCAFT00845042762	ENTREZGENE
	ENSCAFT00845042762.1	UniProtKB/TrEMBL
Gene3D-CATH	EF-hand	UniProtKB/TrEMBL
InterPro	Calbindin_Ca-bind	UniProtKB/TrEMBL
	EF-hand-dom_pair	UniProtKB/TrEMBL
	EF_Hand_1_Ca_BS	UniProtKB/TrEMBL
	EF_hand_dom	UniProtKB/TrEMBL
	EFh_SCGN	UniProtKB/TrEMBL
NCBI Gene	SCGN	ENTREZGENE
PANTHER	CALBINDIN	UniProtKB/TrEMBL
	SECRETAGOGIN	UniProtKB/TrEMBL
Pfam	EF-hand_5	UniProtKB/TrEMBL
	EF-hand_7	UniProtKB/TrEMBL
PROSITE	EF_HAND_1	UniProtKB/TrEMBL
	EF_HAND_2	UniProtKB/TrEMBL
SMART	EFh	UniProtKB/TrEMBL
Superfamily-SCOP	SSF47473	UniProtKB/TrEMBL
UniProt	A0A8C0NYG4	ENTREZGENE, UniProtKB/TrEMBL
	A0A8C0TNH9	ENTREZGENE, UniProtKB/TrEMBL
	A0A8I3S863	ENTREZGENE, UniProtKB/TrEMBL
	A0A8P0SFD5	ENTREZGENE, UniProtKB/TrEMBL
VGNC ID	VGNC:45909	ENTREZGENE

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailable


InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailable


Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
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MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable

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