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Gene: NT5E (5'-nucleotidase ecto) Canis lupus familiaris

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Symbol:

NT5E

Name:

5'-nucleotidase ecto

RGD ID:

12082040

Description:

ENCODES a protein that exhibits 5'-nucleotidase activity (ortholog); ferrous iron binding (ortholog); INVOLVED IN adenosine biosynthetic process (ortholog); adenosine metabolic process (ortholog); AMP catabolic process (ortholog); PARTICIPATES IN hypoxia inducible factor pathway; ASSOCIATED WITH Brain Injuries (ortholog); Disease Progression (ortholog); Experimental Diabetes Mellitus (ortholog); FOUND IN cell surface (ortholog); plasma membrane (ortholog); synaptic membrane (ortholog); INTERACTS WITH carvedilol

Type:

protein-coding

RefSeq Status:

MODEL

Previously known as:

5'-nucleotidase

RGD Orthologs

Alliance Orthologs

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	NT5E (5'-nucleotidase ecto)	HGNC	EggNOG, Ensembl, HomoloGene, NCBI, OMA, OrthoDB, OrthoMCL, Panther, PhylomeDB, Treefam
Mus musculus (house mouse):	Nt5e (5' nucleotidase, ecto)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Rattus norvegicus (Norway rat):	Nt5e (5' nucleotidase, ecto)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Nt5e (5'-nucleotidase ecto)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	NT5E (5'-nucleotidase ecto)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Nt5e (5'-nucleotidase ecto)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	NT5E (5'-nucleotidase ecto)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	NT5E (5'-nucleotidase ecto)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Nt5e (5'-nucleotidase ecto)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline

Latest Assembly:

CanFam3.1 - Dog CanFam3.1 Assembly

Position:

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	12	45,491,028 - 45,520,019 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	12	45,491,733 - 45,518,405 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	12	45,289,507 - 45,334,783 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	12	46,244,000 - 46,289,219 (+)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	12	46,243,992 - 46,289,217 (+)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	12	45,577,415 - 45,622,655 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	12	45,506,318 - 45,551,536 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	12	45,693,314 - 45,738,560 (+)	NCBI		UU_Cfam_GSD_1.0

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Only show annotations with direct experimental evidence (0 objects hidden)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
NT5E	Dog	Brain Injuries		ISO	Nt5e (Rattus norvegicus)	9068941	protein:altered expression:cerebral cortex (rat)	RGD	PMID:21337375 and REF_RGD_ID:5134348
NT5E	Dog	Experimental Diabetes Mellitus		ISO	Nt5e (Rattus norvegicus)	9068941	protein:increased expression:cerebral cortex and synaptosome (rat)	RGD	PMID:19723569 and REF_RGD_ID:5134343
NT5E	Dog	status epilepticus		ISO	Nt5e (Rattus norvegicus)	9068941	protein:increased activity:cerebral cortex and synaptosome (rat)	RGD	PMID:16274951 and REF_RGD_ID:5134344

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
NT5E	Dog	genetic disease		ISO	NT5E (Homo sapiens)	8554872	ClinVar Annotator: match by term: Inborn genetic diseases	ClinVar
NT5E	Dog	hereditary arterial and articular multiple calcification syndrome		ISO	NT5E (Homo sapiens)	8554872	ClinVar more ...	ClinVar	PMID:21288095 more ...

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
NT5E	Dog	Disease Progression		ISO	NT5E (Homo sapiens)	9068941	CTD Direct Evidence: therapeutic	CTD	PMID:34773529
NT5E	Dog	Experimental Liver Cirrhosis		ISO	NT5E (Homo sapiens)	9068941	CTD Direct Evidence: marker/mechanism	CTD	PMID:18263696
NT5E	Dog	Neoplastic Cell Transformation		ISO	NT5E (Homo sapiens)	9068941	CTD Direct Evidence: therapeutic	CTD	PMID:34773529
NT5E	Dog	neuroblastoma		ISO	NT5E (Homo sapiens)	9068941	CTD Direct Evidence: therapeutic	CTD	PMID:34773529
NT5E	Dog	Stomach Neoplasms		ISO	NT5E (Homo sapiens)	9068941	CTD Direct Evidence: marker/mechanism	CTD	PMID:16367923

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
NT5E	Dog	hereditary arterial and articular multiple calcification syndrome		ISO	NT5E (Homo sapiens)	7240710		OMIM

Only show annotations with direct experimental evidence (0 objects hidden)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
NT5E	Dog	carvedilol	increases activity	EXP		6480464	Carvedilol results in increased activity of NT5E protein	CTD	PMID:15148268

Biological Process

Only show annotations with direct experimental evidence (0 objects hidden)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
NT5E	Dog	adenosine biosynthetic process		ISO	Nt5e (Rattus norvegicus)	9068941		RGD	PMID:30269308 and REF_RGD_ID:152995394
NT5E	Dog	adenosine biosynthetic process	acts_upstream_of_or_within	IEA	UniProtKB:Q61503 and ensembl:ENSMUSP00000034992	150520179		Ensembl	GO_REF:0000107
NT5E	Dog	adenosine metabolic process		ISO	Nt5e (Rattus norvegicus)	9068941		RGD	PMID:12675911 and REF_RGD_ID:2291861
NT5E	Dog	ADP catabolic process	involved_in	IEA	UniProtKB:Q61503 and ensembl:ENSMUSP00000034992	150520179		Ensembl	GO_REF:0000107
NT5E	Dog	AMP catabolic process		ISO	Nt5e (Rattus norvegicus)	9068941		RGD	PMID:21414400 more ...
NT5E	Dog	AMP catabolic process	acts_upstream_of_or_within	IEA	UniProtKB:Q61503 and ensembl:ENSMUSP00000034992	150520179		Ensembl	GO_REF:0000107
NT5E	Dog	AMP catabolic process	involved_in	IBA	MGI:99782 more ...	150520179		GO_Central	GO_REF:0000033
NT5E	Dog	ATP metabolic process	involved_in	IEA	UniProtKB:P21589 and ensembl:ENSP00000257770	150520179		Ensembl	GO_REF:0000107
NT5E	Dog	calcium ion homeostasis	involved_in	IEA	UniProtKB:Q61503 and ensembl:ENSMUSP00000034992	150520179		Ensembl	GO_REF:0000107
NT5E	Dog	inhibition of non-skeletal tissue mineralization	involved_in	IEA	UniProtKB:Q61503 and ensembl:ENSMUSP00000034992	150520179		Ensembl	GO_REF:0000107
NT5E	Dog	leukocyte cell-cell adhesion	involved_in	IEA	UniProtKB:P21589 and ensembl:ENSP00000257770	150520179		Ensembl	GO_REF:0000107
NT5E	Dog	negative regulation of inflammatory response	acts_upstream_of_or_within	IEA	UniProtKB:Q61503 and ensembl:ENSMUSP00000034992	150520179		Ensembl	GO_REF:0000107
NT5E	Dog	nucleotide catabolic process	involved_in	IEA	InterPro:IPR006179 more ...	150520179		InterPro	GO_REF:0000002
NT5E	Dog	positive regulation of lipid biosynthetic process		ISO	Nt5e (Rattus norvegicus)	9068941		RGD	PMID:21372807 and REF_RGD_ID:5134347
NT5E	Dog	response to aluminum ion		ISO	Nt5e (Rattus norvegicus)	9068941		RGD	PMID:17686601 and REF_RGD_ID:5134345
NT5E	Dog	response to ATP	involved_in	IEA	UniProtKB:P21589 and ensembl:ENSP00000257770	150520179		Ensembl	GO_REF:0000107

Cellular Component

Only show annotations with direct experimental evidence (0 objects hidden)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
NT5E	Dog	cell surface		ISO	Nt5e (Rattus norvegicus)	9068941		RGD	PMID:21627568 and REF_RGD_ID:5134342
NT5E	Dog	cytosol	located_in	IEA	UniProtKB:P21589 and ensembl:ENSP00000257770	150520179		Ensembl	GO_REF:0000107
NT5E	Dog	external side of plasma membrane	is_active_in	IEA	UniProtKB:Q61503 and ensembl:ENSMUSP00000034992	150520179		Ensembl	GO_REF:0000107
NT5E	Dog	membrane	located_in	IEA	UniProtKB:P21589 more ...	150520179		Ensembl	GO_REF:0000107
NT5E	Dog	membrane	located_in	IEA	UniProtKB-KW:KW-0472	150520179		UniProt	GO_REF:0000043
NT5E	Dog	nucleoplasm	located_in	IEA	UniProtKB:P21589 and ensembl:ENSP00000257770	150520179		Ensembl	GO_REF:0000107
NT5E	Dog	plasma membrane	is_active_in	IBA	MGI:99782 more ...	150520179		GO_Central	GO_REF:0000033
NT5E	Dog	plasma membrane	part_of	ISO	Nt5e (Rattus norvegicus)	9068941	PMID:6017738	CACAO	PMID:6017738 and REF_RGD_ID:10047240
NT5E	Dog	plasma membrane	located_in	IEA	UniProtKB:Q61503 and ensembl:ENSMUSP00000034992	150520179		Ensembl	GO_REF:0000107
NT5E	Dog	plasma membrane	is_active_in	IEA	UniProtKB:P21589 and ensembl:ENSP00000257770	150520179		Ensembl	GO_REF:0000107
NT5E	Dog	synaptic membrane		ISO	Nt5e (Rattus norvegicus)	9068941		RGD	PMID:21414400 and REF_RGD_ID:5134346

Molecular Function

Only show annotations with direct experimental evidence (0 objects hidden)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
NT5E	Dog	5'-deoxynucleotidase activity	enables	IEA	UniProtKB:P21589 and ensembl:ENSP00000257770	150520179		Ensembl	GO_REF:0000107
NT5E	Dog	5'-nucleotidase activity		ISO	Nt5e (Rattus norvegicus)	9068941		RGD	PMID:11935367 more ...
NT5E	Dog	5'-nucleotidase activity	enables	IBA	FB:FBgn0034225 more ...	150520179		GO_Central	GO_REF:0000033
NT5E	Dog	5'-nucleotidase activity	enables	IEA	UniProtKB:P21589 more ...	150520179		Ensembl	GO_REF:0000107
NT5E	Dog	ferrous iron binding		ISO	Nt5e (Rattus norvegicus)	9068941		RGD	PMID:11935367 and REF_RGD_ID:631915
NT5E	Dog	hydrolase activity	enables	IEA	UniProtKB-KW:KW-0378	150520179		UniProt	GO_REF:0000043
NT5E	Dog	hydrolase activity	enables	IEA	InterPro:IPR004843 more ...	150520179		InterPro	GO_REF:0000002
NT5E	Dog	hydrolase activity, acting on ester bonds	enables	IEA	InterPro:IPR006146	150520179		InterPro	GO_REF:0000002
NT5E	Dog	identical protein binding	enables	IEA	UniProtKB:P21589 and ensembl:ENSP00000257770	150520179		Ensembl	GO_REF:0000107
NT5E	Dog	metal ion binding	enables	IEA	InterPro:IPR006146	150520179		InterPro	GO_REF:0000002
NT5E	Dog	nucleotide binding	enables	IEA	InterPro:IPR006146	150520179		InterPro	GO_REF:0000002
NT5E	Dog	nucleotide binding	enables	IEA	UniProtKB-KW:KW-0547	150520179		UniProt	GO_REF:0000043
NT5E	Dog	obsolete GMP 5'-nucleotidase activity	enables	IEA	UniProtKB:P21589 and ensembl:ENSP00000257770	150520179		Ensembl	GO_REF:0000107
NT5E	Dog	obsolete IMP 5'-nucleotidase activity	enables	IEA	UniProtKB:P21589 and ensembl:ENSP00000257770	150520179		Ensembl	GO_REF:0000107
NT5E	Dog	obsolete thymidylate 5'-phosphatase activity	enables	IEA	UniProtKB:P21589 and ensembl:ENSP00000257770	150520179		Ensembl	GO_REF:0000107
NT5E	Dog	protein binding	enables	ISO	UniProtKB:Q8WWF5 and UniProtKB:Q9Y225-2	9068941	PMID:32296183	IntAct	PMID:32296183
NT5E	Dog	zinc ion binding	enables	IEA	UniProtKB:P21589 and ensembl:ENSP00000257770	150520179		Ensembl	GO_REF:0000107

Imported Annotations - PID (archival)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
NT5E	Dog	hypoxia inducible factor pathway		ISO	NT5E (Homo sapiens)	9068941		PID	PID:200202

PMID:22301074	PMID:30032202

NT5E
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	12	45,491,028 - 45,520,019 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	12	45,491,733 - 45,518,405 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	12	45,289,507 - 45,334,783 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	12	46,244,000 - 46,289,219 (+)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	12	46,243,992 - 46,289,217 (+)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	12	45,577,415 - 45,622,655 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	12	45,506,318 - 45,551,536 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	12	45,693,314 - 45,738,560 (+)	NCBI		UU_Cfam_GSD_1.0

NT5E
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	6	85,450,083 - 85,495,784 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	6	85,449,584 - 85,495,791 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	6	86,159,801 - 86,205,502 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	6	86,216,528 - 86,262,215 (+)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	6	86,216,527 - 86,262,215	NCBI
Celera	6	86,586,482 - 86,632,679 (+)	NCBI		Celera
Cytogenetic Map	6	q14.3	NCBI
HuRef	6	83,383,590 - 83,429,793 (+)	NCBI		HuRef
CHM1_1	6	86,257,244 - 86,303,451 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	6	86,666,882 - 86,712,587 (+)	NCBI		T2T-CHM13v2.0

Nt5e
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	9	88,209,662 - 88,254,142 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	9	88,209,250 - 88,254,145 (+)	Ensembl		GRCm39 Ensembl
GRCm38	9	88,327,609 - 88,372,089 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	9	88,327,197 - 88,372,092 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	9	88,222,447 - 88,266,927 (+)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	9	88,125,533 - 88,169,982 (+)	NCBI		MGSCv36	mm8
Celera	9	85,354,734 - 85,399,137 (+)	NCBI		Celera
Cytogenetic Map	9	E3.1	NCBI
cM Map	9	47.24	NCBI

Nt5e
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	8	98,150,925 - 98,195,646 (+)	NCBI		GRCr8
mRatBN7.2	8	89,271,046 - 89,314,918 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	8	89,270,696 - 89,314,881 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	8	94,940,630 - 94,984,431 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	8	93,139,844 - 93,183,642 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	8	90,998,970 - 91,042,930 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	8	95,969,002 - 96,012,733 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	8	95,968,652 - 96,012,696 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	8	95,464,591 - 95,508,322 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	8	93,591,630 - 93,635,481 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	8	93,610,734 - 93,654,911 (+)	NCBI
Celera	8	88,841,425 - 88,885,302 (+)	NCBI		Celera
Cytogenetic Map	8	q31	NCBI

Nt5e
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955411	12,891,236 - 12,948,406 (+)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955411	12,891,236 - 12,946,324 (+)	NCBI	ChiLan1.0	ChiLan1.0

NT5E
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	5	105,532,410 - 105,584,140 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	6	103,429,147 - 103,478,675 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	6	83,333,428 - 83,379,585 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	6	86,615,409 - 86,661,594 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	6	86,615,409 - 86,661,601 (+)	Ensembl	panpan1.1		panPan2

Nt5e
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024404946	80,624,771 - 80,673,677 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936510	5,797,212 - 5,846,124 (-)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936510	5,797,218 - 5,846,118 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

NT5E
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	1	54,400,810 - 54,448,742 (+)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	1	54,400,786 - 54,450,743 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	1	60,831,831 - 60,881,527 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

NT5E
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	13	10,115,591 - 10,162,178 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	13	10,116,161 - 10,160,414 (+)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666040	186,303,608 - 186,348,855 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Nt5e
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624799	8,765,711 - 8,845,778 (-)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624799	8,766,608 - 8,845,296 (-)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Variants in NT5E
361 total Variants

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

adipose tissue	alimentary part of gastrointestinal system	circulatory system	ectoderm	endocrine system	endoderm	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	mesenchyme	mesoderm	nervous system	reproductive system	respiratory system
6	5	5	23	22	16	6	6	6	6	33	22	12	14	10


RefSeq Transcripts	XM_038492362	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038554649	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038618522	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038675165	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038684083	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_532221	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AAEX04000012	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAAHUQ010000125	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAAQRD010000012	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAAUVH010000357	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	REHQ01000012	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSCAFT00000004810 ⟹ ENSCAFP00000004456

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
CanFam3.1 Ensembl	12	45,491,733 - 45,518,405 (+)	Ensembl

Ensembl Acc Id:

ENSCAFT00845023054 ⟹ ENSCAFP00845018086

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
ROS_Cfam_1.0 Ensembl	12	46,243,992 - 46,289,217 (+)	Ensembl

Ensembl Acc Id:

ENSCAFT00845023147 ⟹ ENSCAFP00845018148

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
ROS_Cfam_1.0 Ensembl	12	46,243,992 - 46,289,217 (+)	Ensembl

RefSeq Acc Id:

XM_038492362 ⟹ XP_038348290

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
UMICH_Zoey_3.1	12	45,577,415 - 45,622,655 (+)	NCBI

RefSeq Acc Id:

XM_038554649 ⟹ XP_038410577

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
UU_Cfam_GSD_1.0	12	45,693,314 - 45,738,560 (+)	NCBI

RefSeq Acc Id:

XM_038618522 ⟹ XP_038474450

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
UNSW_CanFamBas_1.0	12	45,506,318 - 45,551,536 (+)	NCBI

RefSeq Acc Id:

XM_038675165 ⟹ XP_038531093

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
Dog10K_Boxer_Tasha	12	45,289,507 - 45,334,783 (+)	NCBI

RefSeq Acc Id:

XM_038684083 ⟹ XP_038540011

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
ROS_Cfam_1.0	12	46,244,000 - 46,289,219 (+)	NCBI


Protein RefSeqs	XP_038348290	(Get FASTA)	NCBI Sequence Viewer
	XP_038410577	(Get FASTA)	NCBI Sequence Viewer
	XP_038474450	(Get FASTA)	NCBI Sequence Viewer
	XP_038531093	(Get FASTA)	NCBI Sequence Viewer
	XP_038540011	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSCAFP00000004456.4
	ENSCAFP00000074190.1
	ENSCAFP00030024230.1
	ENSCAFP00030024276.1
	ENSCAFP00030024338.1
	ENSCAFP00030024429.1
	ENSCAFP00030024488.1
	ENSCAFP00030024524.1
	ENSCAFP00030024566.1
	ENSCAFP00040012534.1
	ENSCAFP00040012559.1
	ENSCAFP00040012594.1
	ENSCAFP00845018086
	ENSCAFP00845018086.1
	ENSCAFP00845018148.1

Ensembl Acc Id:

ENSCAFP00000004456 ⟸ ENSCAFT00000004810

RefSeq Acc Id:

XP_038348290 ⟸ XM_038492362

RefSeq Acc Id:

XP_038474450 ⟸ XM_038618522

RefSeq Acc Id:	XP_038540011 ⟸ XM_038684083
- UniProtKB:	A0A8C0NBJ4 (UniProtKB/TrEMBL), A0A8I3NIC2 (UniProtKB/TrEMBL), A0A8C0KT91 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_038531093 ⟸ XM_038675165
- UniProtKB:	A0A8C0NBJ4 (UniProtKB/TrEMBL), A0A8I3NIC2 (UniProtKB/TrEMBL), A0A8C0KT91 (UniProtKB/TrEMBL)

Protein Domains

5'-Nucleotidase C-terminal Calcineurin-like phosphoesterase

Database	Acc Id	Source(s)
Ensembl Genes	ENSCAFG00000002994	Ensembl, UniProtKB/TrEMBL
	ENSCAFG00030015025	UniProtKB/TrEMBL
	ENSCAFG00040007790	UniProtKB/TrEMBL
	ENSCAFG00845012948	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSCAFT00000004810.5	UniProtKB/TrEMBL
	ENSCAFT00000107397.1	UniProtKB/TrEMBL
	ENSCAFT00030027768.1	UniProtKB/TrEMBL
	ENSCAFT00030027817.1	UniProtKB/TrEMBL
	ENSCAFT00030027890.1	UniProtKB/TrEMBL
	ENSCAFT00030027990.1	UniProtKB/TrEMBL
	ENSCAFT00030028057.1	UniProtKB/TrEMBL
	ENSCAFT00030028097.1	UniProtKB/TrEMBL
	ENSCAFT00030028151.1	UniProtKB/TrEMBL
	ENSCAFT00040014490.1	UniProtKB/TrEMBL
	ENSCAFT00040014525.1	UniProtKB/TrEMBL
	ENSCAFT00040014564.1	UniProtKB/TrEMBL
	ENSCAFT00845023054	ENTREZGENE
	ENSCAFT00845023054.1	UniProtKB/TrEMBL
	ENSCAFT00845023147.1	UniProtKB/TrEMBL
Gene3D-CATH	3.60.21.10	UniProtKB/TrEMBL
	3.90.780.10	UniProtKB/TrEMBL
InterPro	5'-Nucleotdase_C	UniProtKB/TrEMBL
	5'-Nucleotdase_C_sf	UniProtKB/TrEMBL
	5'-Nucleotdase_CS	UniProtKB/TrEMBL
	5_nucleotidase/apyrase	UniProtKB/TrEMBL
	Calcineurin-like_PHP_ApaH	UniProtKB/TrEMBL
	Metallo-depent_PP-like	UniProtKB/TrEMBL
NCBI Gene	NT5E	ENTREZGENE
PANTHER	5'-NUCLEOTIDASE	UniProtKB/TrEMBL
	PTHR11575	UniProtKB/TrEMBL
Pfam	5_nucleotid_C	UniProtKB/TrEMBL
	Metallophos	UniProtKB/TrEMBL
PRINTS	APYRASEFAMLY	UniProtKB/TrEMBL
PROSITE	5_NUCLEOTIDASE_1	UniProtKB/TrEMBL
	5_NUCLEOTIDASE_2	UniProtKB/TrEMBL
Superfamily-SCOP	SSF55816	UniProtKB/TrEMBL
	SSF56300	UniProtKB/TrEMBL
UniProt	A0A8C0KT91	ENTREZGENE
	A0A8C0NB61_CANLF	UniProtKB/TrEMBL
	A0A8C0NBB2_CANLF	UniProtKB/TrEMBL
	A0A8C0NBJ4	ENTREZGENE, UniProtKB/TrEMBL
	A0A8C0NG09_CANLF	UniProtKB/TrEMBL
	A0A8C0NG45_CANLF	UniProtKB/TrEMBL
	A0A8C0NGQ0_CANLF	UniProtKB/TrEMBL
	A0A8C0NHC3_CANLF	UniProtKB/TrEMBL
	A0A8I3NEG1_CANLF	UniProtKB/TrEMBL
	A0A8I3NIC2	ENTREZGENE, UniProtKB/TrEMBL
VGNC ID	VGNC:44000	ENTREZGENE

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailable


InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailable


Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
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MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable

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Imported Disease Annotations - OMIM

Imported Annotations - PID (archival)

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Imported Disease Annotations - ClinVar

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Imported Disease Annotations - OMIM

Imported Annotations - PID (archival)