NT5E (5'-nucleotidase ecto) - Rat Genome Database

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Gene: NT5E (5'-nucleotidase ecto) Pan paniscus
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Symbol: NT5E
Name: 5'-nucleotidase ecto
RGD ID: 12022224
Description: ENCODES a protein that exhibits 5'-nucleotidase activity (ortholog); ferrous iron binding (ortholog); INVOLVED IN adenosine biosynthetic process (ortholog); adenosine metabolic process (ortholog); AMP catabolic process (ortholog); PARTICIPATES IN hypoxia inducible factor pathway; ASSOCIATED WITH Brain Injuries (ortholog); Disease Progression (ortholog); Experimental Diabetes Mellitus (ortholog); FOUND IN cell surface (ortholog); external side of plasma membrane (ortholog); plasma membrane (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: 5'-nucleotidase
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly
Position:
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v25105,532,410 - 105,584,140 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan16103,429,147 - 103,478,675 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0683,333,428 - 83,379,585 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1686,615,409 - 86,661,594 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl686,615,409 - 86,661,601 (+)Ensemblpanpan1.1panPan2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Molecular Pathway Annotations     Click to see Annotation Detail View
References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
NT5E
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v25105,532,410 - 105,584,140 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan16103,429,147 - 103,478,675 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0683,333,428 - 83,379,585 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1686,615,409 - 86,661,594 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl686,615,409 - 86,661,601 (+)Ensemblpanpan1.1panPan2
NT5E
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38685,450,083 - 85,495,784 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl685,449,584 - 85,495,791 (+)EnsemblGRCh38hg38GRCh38
GRCh37686,159,801 - 86,205,502 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36686,216,528 - 86,262,215 (+)NCBINCBI36Build 36hg18NCBI36
Build 34686,216,527 - 86,262,215NCBI
Celera686,586,482 - 86,632,679 (+)NCBICelera
Cytogenetic Map6q14.3NCBI
HuRef683,383,590 - 83,429,793 (+)NCBIHuRef
CHM1_1686,257,244 - 86,303,451 (+)NCBICHM1_1
T2T-CHM13v2.0686,666,882 - 86,712,587 (+)NCBIT2T-CHM13v2.0
Nt5e
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39988,209,662 - 88,254,142 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl988,209,250 - 88,254,145 (+)EnsemblGRCm39 Ensembl
GRCm38988,327,609 - 88,372,089 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl988,327,197 - 88,372,092 (+)EnsemblGRCm38mm10GRCm38
MGSCv37988,222,447 - 88,266,927 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36988,125,533 - 88,169,982 (+)NCBIMGSCv36mm8
Celera985,354,734 - 85,399,137 (+)NCBICelera
Cytogenetic Map9E3.1NCBI
cM Map947.24NCBI
Nt5e
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8898,150,925 - 98,195,646 (+)NCBIGRCr8
mRatBN7.2889,271,046 - 89,314,918 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl889,270,696 - 89,314,881 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx894,940,630 - 94,984,431 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0893,139,844 - 93,183,642 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0890,998,970 - 91,042,930 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0895,969,002 - 96,012,733 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl895,968,652 - 96,012,696 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0895,464,591 - 95,508,322 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4893,591,630 - 93,635,481 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1893,610,734 - 93,654,911 (+)NCBI
Celera888,841,425 - 88,885,302 (+)NCBICelera
Cytogenetic Map8q31NCBI
Nt5e
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495541112,891,236 - 12,948,406 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495541112,891,236 - 12,946,324 (+)NCBIChiLan1.0ChiLan1.0
NT5E
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11245,491,028 - 45,520,019 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1245,491,733 - 45,518,405 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1245,289,507 - 45,334,783 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01246,244,000 - 46,289,219 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1246,243,992 - 46,289,217 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11245,577,415 - 45,622,655 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01245,506,318 - 45,551,536 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01245,693,314 - 45,738,560 (+)NCBIUU_Cfam_GSD_1.0
Nt5e
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494680,624,771 - 80,673,677 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365105,797,212 - 5,846,124 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365105,797,218 - 5,846,118 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
NT5E
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl154,400,810 - 54,448,742 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1154,400,786 - 54,450,743 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2160,831,831 - 60,881,527 (+)NCBISscrofa10.2Sscrofa10.2susScr3
NT5E
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11310,115,591 - 10,162,178 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1310,116,161 - 10,160,414 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666040186,303,608 - 186,348,855 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Nt5e
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247998,765,711 - 8,845,778 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247998,766,608 - 8,845,296 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression

RNA-SEQ Expression


Sequence


Ensembl Acc Id: ENSPPAT00000046915   ⟹   ENSPPAP00000024090
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl686,615,409 - 86,661,601 (+)Ensembl
Ensembl Acc Id: ENSPPAT00000046920   ⟹   ENSPPAP00000024095
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl686,615,965 - 86,659,812 (+)Ensembl
RefSeq Acc Id: XM_003822843   ⟹   XP_003822891
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v25105,532,417 - 105,584,140 (+)NCBI
NHGRI_mPanPan16103,429,147 - 103,478,675 (+)NCBI
Mhudiblu_PPA_v0683,333,428 - 83,379,585 (+)NCBI
PanPan1.1686,615,409 - 86,661,594 (+)NCBI
Sequence:
RefSeq Acc Id: XM_063605407   ⟹   XP_063461477
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v25105,532,410 - 105,579,597 (+)NCBI
Protein Sequences
Protein RefSeqs XP_003822891 (Get FASTA)   NCBI Sequence Viewer  
  XP_063461477 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSPPAP00000024090
  ENSPPAP00000024090.1
  ENSPPAP00000024095.1
RefSeq Acc Id: XP_003822891   ⟸   XM_003822843
- Peptide Label: isoform X1
- UniProtKB: A0A2R9B776 (UniProtKB/TrEMBL),   A0A2R9B781 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSPPAP00000024090   ⟸   ENSPPAT00000046915
Ensembl Acc Id: ENSPPAP00000024095   ⟸   ENSPPAT00000046920
RefSeq Acc Id: XP_063461477   ⟸   XM_063605407
- Peptide Label: isoform X2

Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSPPAG00000035188 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSPPAT00000046915.1 UniProtKB/TrEMBL
  ENSPPAT00000046920.1 UniProtKB/TrEMBL
Gene3D-CATH 3.60.21.10 UniProtKB/TrEMBL
  3.90.780.10 UniProtKB/TrEMBL
InterPro 5'-Nucleotdase_C UniProtKB/TrEMBL
  5'-Nucleotdase_C_sf UniProtKB/TrEMBL
  5'-Nucleotdase_CS UniProtKB/TrEMBL
  5_nucleotidase/apyrase UniProtKB/TrEMBL
  Calcineurin-like_PHP_ApaH UniProtKB/TrEMBL
  Metallo-depent_PP-like UniProtKB/TrEMBL
KEGG Report pps:100985138 UniProtKB/TrEMBL
NCBI Gene NT5E ENTREZGENE
PANTHER 5'-NUCLEOTIDASE UniProtKB/TrEMBL
  PTHR11575 UniProtKB/TrEMBL
Pfam 5_nucleotid_C UniProtKB/TrEMBL
  Metallophos UniProtKB/TrEMBL
PRINTS APYRASEFAMLY UniProtKB/TrEMBL
PROSITE 5_NUCLEOTIDASE_1 UniProtKB/TrEMBL
  5_NUCLEOTIDASE_2 UniProtKB/TrEMBL
Superfamily-SCOP SSF55816 UniProtKB/TrEMBL
  SSF56300 UniProtKB/TrEMBL
UniProt A0A2R9B776 ENTREZGENE, UniProtKB/TrEMBL
  A0A2R9B781 ENTREZGENE, UniProtKB/TrEMBL