TNFAIP1 (TNF alpha induced protein 1) - Rat Genome Database

Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Gene: TNFAIP1 (TNF alpha induced protein 1) Canis lupus familiaris
Analyze
Symbol: TNFAIP1
Name: TNF alpha induced protein 1
RGD ID: 12066550
Description: ENCODES a protein that exhibits cyclin binding (ortholog); INVOLVED IN positive regulation of DNA replication (ortholog); ASSOCIATED WITH Diabetic Nephropathies (ortholog); FOUND IN Cul3-RING ubiquitin ligase complex (inferred); cytoplasm (inferred); endosome (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 2
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: CanFam3.1 - Dog CanFam3.1 Assembly
Position:
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1942,588,009 - 42,597,961 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl942,588,112 - 42,595,596 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha941,744,941 - 41,754,881 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0943,407,163 - 43,417,110 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl943,407,185 - 43,417,107 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1942,191,412 - 42,201,351 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0942,482,639 - 42,492,584 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0942,559,687 - 42,569,626 (+)NCBIUU_Cfam_GSD_1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
TNFAIP1DogDiabetic Nephropathies  ISOTNFAIP1 (Homo sapiens)9068941CTD Direct Evidence: marker/mechanismCTDPMID:20665664


Biological Process
1 to 11 of 11 rows

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
TNFAIP1Dogcell migration involved_inIEAUniProtKB:Q13829 and ensembl:ENSP00000226225150520179 EnsemblGO_REF:0000107
TNFAIP1Dogimmune response involved_inIEAUniProtKB:Q13829 and ensembl:ENSP00000226225150520179 EnsemblGO_REF:0000107
TNFAIP1Dognegative regulation of Rho protein signal transduction involved_inIEAUniProtKB:Q13829 and ensembl:ENSP00000226225150520179 EnsemblGO_REF:0000107
TNFAIP1Dognegative regulation of Rho protein signal transduction involved_inIBAMGI:1923739 more ...150520179 GO_CentralGO_REF:0000033
TNFAIP1Dogpositive regulation of DNA replication  ISOTnfaip1 (Rattus norvegicus)9068941 RGDPMID:15726626 and REF_RGD_ID:1357162
TNFAIP1Dogproteasome-mediated ubiquitin-dependent protein catabolic process involved_inIEAUniProtKB:Q13829 and ensembl:ENSP00000226225150520179 EnsemblGO_REF:0000107
TNFAIP1Dogproteasome-mediated ubiquitin-dependent protein catabolic process involved_inIBAPANTHER:PTN000125051 more ...150520179 GO_CentralGO_REF:0000033
TNFAIP1Dogprotein homooligomerization involved_inIEAInterPro:IPR003131150520179 InterProGO_REF:0000002
TNFAIP1Dogprotein ubiquitination involved_inIBAPANTHER:PTN000125051 more ...150520179 GO_CentralGO_REF:0000033
TNFAIP1Dogprotein ubiquitination involved_inIEAUniProtKB:Q13829 and ensembl:ENSP00000226225150520179 EnsemblGO_REF:0000107
TNFAIP1Dogstress fiber assembly involved_inIEAUniProtKB:Q13829 and ensembl:ENSP00000226225150520179 EnsemblGO_REF:0000107
1 to 11 of 11 rows

Cellular Component

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
TNFAIP1DogCul3-RING ubiquitin ligase complex part_ofIBAPANTHER:PTN000125051 more ...150520179 GO_CentralGO_REF:0000033
TNFAIP1DogCul3-RING ubiquitin ligase complex part_ofIEAUniProtKB:Q13829 and ensembl:ENSP00000226225150520179 EnsemblGO_REF:0000107
TNFAIP1Dogcytoplasm located_inIEAUniProtKB:Q13829 and ensembl:ENSP00000226225150520179 EnsemblGO_REF:0000107
TNFAIP1Dogcytoplasm located_inIEAUniProtKB-SubCell:SL-0086150520179 UniProtGO_REF:0000044
TNFAIP1Dogendosome located_inIEAUniProtKB:Q13829 and ensembl:ENSP00000226225150520179 EnsemblGO_REF:0000107
TNFAIP1Dogendosome located_inIEAUniProtKB-KW:KW-0967150520179 UniProtGO_REF:0000043
TNFAIP1Dogendosome located_inIEAUniProtKB-SubCell:SL-0101150520179 UniProtGO_REF:0000044
TNFAIP1Dognucleus located_inIEAUniProtKB-SubCell:SL-0191150520179 UniProtGO_REF:0000044

Molecular Function
1 to 14 of 14 rows

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
TNFAIP1Dogcyclin binding  ISOPcna (Rattus norvegicus)9068941 RGDPMID:15726626 and REF_RGD_ID:1357162
TNFAIP1Dogidentical protein binding enablesIEAUniProtKB:Q13829 and ensembl:ENSP00000226225150520179 EnsemblGO_REF:0000107
TNFAIP1Dogprotein binding enablesISOUniProtKB:P049619068941PMID:15726626UniProtPMID:15726626 and REF_RGD_ID:1357162
TNFAIP1Dogprotein binding enablesISOUniProtKB:Q136189068941 PMID:21145461 and PMID:34591642IntActPMID:21145461 and PMID:34591642
TNFAIP1Dogprotein binding enablesISOUniProtKB:O14929 more ...9068941 PMID:25416956IntActPMID:25416956
TNFAIP1Dogprotein binding enablesISOUniProtKB:P00441 more ...9068941 PMID:32814053IntActPMID:32814053
TNFAIP1Dogprotein binding enablesISOUniProtKB:O151609068941 PMID:21988832IntActPMID:21988832
TNFAIP1Dogprotein binding enablesISOUniProtKB:Q8WZ199068941 PMID:19615732 and PMID:28514442IntActPMID:19615732 and PMID:28514442
TNFAIP1Dogprotein binding enablesISOUniProtKB:O15160 more ...9068941 PMID:32296183IntActPMID:32296183
TNFAIP1Dogprotein binding enablesISOUniProtKB:Q13618 more ...9068941 PMID:33961781IntActPMID:33961781
TNFAIP1Dogprotein binding enablesISOUniProtKB:P627459068941 PMID:19637314IntActPMID:19637314
TNFAIP1Dogsmall GTPase binding enablesIEAUniProtKB:Q13829 and ensembl:ENSP00000226225150520179 EnsemblGO_REF:0000107
TNFAIP1Dogubiquitin-protein transferase activity contributes_toIEAUniProtKB:Q13829 and ensembl:ENSP00000226225150520179 EnsemblGO_REF:0000107
TNFAIP1Dogubiquitin-protein transferase activity contributes_toIBAPANTHER:PTN000125051 more ...150520179 GO_CentralGO_REF:0000033
1 to 14 of 14 rows

PMID:22301074   PMID:30032202  



TNFAIP1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1942,588,009 - 42,597,961 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl942,588,112 - 42,595,596 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha941,744,941 - 41,754,881 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0943,407,163 - 43,417,110 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl943,407,185 - 43,417,107 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1942,191,412 - 42,201,351 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0942,482,639 - 42,492,584 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0942,559,687 - 42,569,626 (+)NCBIUU_Cfam_GSD_1.0
TNFAIP1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381728,335,761 - 28,347,009 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1728,335,602 - 28,347,009 (+)EnsemblGRCh38hg38GRCh38
GRCh371726,662,787 - 26,674,035 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361723,686,913 - 23,698,160 (+)NCBINCBI36Build 36hg18NCBI36
Build 341723,686,912 - 23,698,160NCBI
Celera1723,524,290 - 23,535,780 (+)NCBICelera
Cytogenetic Map17q11.2NCBI
HuRef1722,870,942 - 22,882,432 (+)NCBIHuRef
CHM1_11726,725,440 - 26,736,930 (+)NCBICHM1_1
T2T-CHM13v2.01729,277,609 - 29,288,860 (+)NCBIT2T-CHM13v2.0
Tnfaip1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391178,413,676 - 78,427,122 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1178,413,676 - 78,427,158 (-)EnsemblGRCm39 Ensembl
GRCm381178,522,850 - 78,536,270 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1178,522,850 - 78,536,332 (-)EnsemblGRCm38mm10GRCm38
MGSCv371178,336,352 - 78,349,762 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361178,339,043 - 78,352,389 (-)NCBIMGSCv36mm8
Celera1188,154,923 - 88,168,333 (-)NCBICelera
Cytogenetic Map11B5NCBI
cM Map1146.74NCBI
Tnfaip1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81063,915,824 - 63,930,514 (-)NCBIGRCr8
mRatBN7.21063,417,774 - 63,432,466 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1063,417,775 - 63,432,466 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1068,050,427 - 68,065,093 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01067,555,758 - 67,570,424 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01063,025,275 - 63,039,976 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01065,791,002 - 65,805,693 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1065,791,003 - 65,805,693 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01065,837,922 - 65,853,370 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41064,632,189 - 64,646,879 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11064,647,455 - 64,660,389 (-)NCBI
Celera1062,394,329 - 62,409,019 (-)NCBICelera
Cytogenetic Map10q25NCBI
Tnfaip1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554814,786,015 - 4,799,274 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554814,786,015 - 4,799,376 (-)NCBIChiLan1.0ChiLan1.0
TNFAIP1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21936,111,643 - 36,122,935 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11737,992,035 - 38,003,328 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01728,427,448 - 28,438,826 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11728,929,788 - 28,941,278 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1728,929,788 - 28,941,278 (-)Ensemblpanpan1.1panPan2
Tnfaip1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440560241,613,977 - 41,625,942 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365384,491,925 - 4,503,645 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365384,491,915 - 4,503,887 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
TNFAIP1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1244,616,916 - 44,629,934 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11244,616,840 - 44,626,330 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21246,529,322 - 46,538,741 (+)NCBISscrofa10.2Sscrofa10.2susScr3
TNFAIP1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11622,102,499 - 22,111,739 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1622,102,531 - 22,115,451 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660758,014,614 - 8,026,413 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Tnfaip1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_004624786939,605 - 952,675 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_004624786939,619 - 952,698 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

.

.
Variants in TNFAIP1
117 total Variants



adipose tissue
alimentary part of gastrointestinal system
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
reproductive system
respiratory system
6 5 5 23 22 16 6 6 6 6 33 22 12 14 10



Ensembl Acc Id: ENSCAFT00000029628   ⟹   ENSCAFP00000027535
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl942,588,112 - 42,595,596 (+)Ensembl
Ensembl Acc Id: ENSCAFT00845012326   ⟹   ENSCAFP00845009635
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl943,407,185 - 43,417,107 (+)Ensembl
Ensembl Acc Id: ENSCAFT00845012374   ⟹   ENSCAFP00845009674
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl943,407,185 - 43,415,074 (+)Ensembl
RefSeq Acc Id: XM_038486388   ⟹   XP_038342316
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.1942,191,412 - 42,201,351 (+)NCBI
RefSeq Acc Id: XM_038548226   ⟹   XP_038404154
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.0942,559,687 - 42,569,626 (+)NCBI
RefSeq Acc Id: XM_038612191   ⟹   XP_038468119
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.0942,482,639 - 42,492,584 (+)NCBI
RefSeq Acc Id: XM_038677449   ⟹   XP_038533377
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0943,407,163 - 43,417,110 (+)NCBI
RefSeq Acc Id: XM_548281   ⟹   XP_548281
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1942,588,009 - 42,597,961 (+)NCBI
Dog10K_Boxer_Tasha941,744,941 - 41,754,881 (+)NCBI
Sequence:
RefSeq Acc Id: XP_548281   ⟸   XM_548281
- UniProtKB: A0A8C0T9F1 (UniProtKB/TrEMBL),   A0A8C0KHF8 (UniProtKB/TrEMBL),   A0A8I3NFW8 (UniProtKB/TrEMBL),   A0A8C0KFZ5 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSCAFP00000027535   ⟸   ENSCAFT00000029628
RefSeq Acc Id: XP_038342316   ⟸   XM_038486388
RefSeq Acc Id: XP_038468119   ⟸   XM_038612191
RefSeq Acc Id: XP_038533377   ⟸   XM_038677449
- UniProtKB: A0A8C0T9F1 (UniProtKB/TrEMBL),   A0A8C0KHF8 (UniProtKB/TrEMBL),   A0A8I3NFW8 (UniProtKB/TrEMBL),   A0A8C0KFZ5 (UniProtKB/TrEMBL)
BTB



1 to 29 of 29 rows
Database
Acc Id
Source(s)
Ensembl Genes ENSCAFG00000018663 Ensembl, UniProtKB/TrEMBL
  ENSCAFG00030013883 UniProtKB/TrEMBL
  ENSCAFG00040020100 UniProtKB/TrEMBL
  ENSCAFG00845006938 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCAFT00000029628.5 UniProtKB/TrEMBL
  ENSCAFT00030025736.1 UniProtKB/TrEMBL
  ENSCAFT00040037151.1 UniProtKB/TrEMBL
  ENSCAFT00845012326 ENTREZGENE
  ENSCAFT00845012326.1 UniProtKB/TrEMBL
  ENSCAFT00845012374.1 UniProtKB/TrEMBL
Gene3D-CATH Potassium Channel Kv1.1, Chain A UniProtKB/TrEMBL
InterPro BACURD1-3 UniProtKB/TrEMBL
  BTB/POZ_dom UniProtKB/TrEMBL
  SKP1/BTB/POZ_sf UniProtKB/TrEMBL
  T1-type_BTB UniProtKB/TrEMBL
KEGG Report cfa:491161 UniProtKB/TrEMBL
NCBI Gene TNFAIP1 ENTREZGENE
PANTHER BTB/POZ DOMAIN-CONTAINING ADAPTER FOR CUL3-MEDIATED RHOA DEGRADATION PROTEIN 2 UniProtKB/TrEMBL
  PTHR11145 UniProtKB/TrEMBL
Pfam BTB_2 UniProtKB/TrEMBL
PROSITE BTB UniProtKB/TrEMBL
SMART BTB UniProtKB/TrEMBL
Superfamily-SCOP SSF54695 UniProtKB/TrEMBL
UniProt A0A8C0KFZ5 ENTREZGENE
  A0A8C0KHF8 ENTREZGENE
  A0A8C0T9F1 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I3NFW8 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I3RTN3_CANLF UniProtKB/TrEMBL
VGNC ID VGNC:47648 ENTREZGENE
1 to 29 of 29 rows