SGSM1 (small G protein signaling modulator 1) - Rat Genome Database

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Gene: SGSM1 (small G protein signaling modulator 1) Pan paniscus
Analyze
Symbol: SGSM1
Name: small G protein signaling modulator 1
RGD ID: 12016652
Description: ENCODES a protein that exhibits GTPase activator activity (inferred); small GTPase binding (inferred); INVOLVED IN positive regulation of transcription by RNA polymerase II (ortholog); FOUND IN cytoplasm (ortholog)
Type: protein-coding
RefSeq Status: MODEL
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly
Position:
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22334,705,565 - 34,826,547 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12237,403,798 - 37,525,340 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0225,761,495 - 5,882,410 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12223,429,802 - 23,549,021 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2223,429,702 - 23,546,446 (+)Ensemblpanpan1.1panPan2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
SGSM1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22334,705,565 - 34,826,547 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12237,403,798 - 37,525,340 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0225,761,495 - 5,882,410 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12223,429,802 - 23,549,021 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2223,429,702 - 23,546,446 (+)Ensemblpanpan1.1panPan2
SGSM1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382224,806,211 - 24,927,578 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2224,806,169 - 24,927,578 (+)EnsemblGRCh38hg38GRCh38
GRCh372225,202,178 - 25,323,545 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 362223,532,136 - 23,652,813 (+)NCBINCBI36Build 36hg18NCBI36
Celera229,006,548 - 9,127,191 (+)NCBICelera
Cytogenetic Map22q11.23NCBI
HuRef228,151,216 - 8,271,579 (+)NCBIHuRef
CHM1_12225,161,077 - 25,281,547 (+)NCBICHM1_1
T2T-CHM13v2.02225,267,600 - 25,389,136 (+)NCBIT2T-CHM13v2.0
Sgsm1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm395113,391,086 - 113,458,654 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl5113,391,086 - 113,458,652 (-)EnsemblGRCm39 Ensembl
GRCm385113,243,220 - 113,310,788 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl5113,243,220 - 113,310,786 (-)EnsemblGRCm38mm10GRCm38
MGSCv375113,672,240 - 113,739,806 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv365113,483,532 - 113,551,022 (-)NCBIMGSCv36mm8
Celera5110,363,560 - 110,432,092 (-)NCBICelera
Cytogenetic Map5FNCBI
cM Map555.45NCBI
Sgsm1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81248,969,578 - 49,049,110 (+)NCBIGRCr8
mRatBN7.21243,320,500 - 43,386,469 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1243,321,256 - 43,386,457 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1244,487,875 - 44,552,684 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01245,100,490 - 45,165,694 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01244,161,013 - 44,226,220 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01249,329,093 - 49,395,078 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1249,328,977 - 49,395,125 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01251,102,730 - 51,169,362 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41244,329,807 - 44,395,211 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11244,211,959 - 44,256,802 (+)NCBI
Celera1244,917,920 - 44,983,077 (+)NCBICelera
Cytogenetic Map12q16NCBI
Sgsm1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_004955455260,410 - 343,253 (-)EnsemblChiLan1.0
ChiLan1.0NW_004955455258,472 - 343,079 (-)NCBIChiLan1.0ChiLan1.0
SGSM1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12618,977,100 - 19,057,190 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2618,976,361 - 19,075,458 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2618,843,281 - 18,923,350 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02619,342,265 - 19,422,695 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2619,342,236 - 19,422,695 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12619,048,218 - 19,126,544 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02619,312,628 - 19,393,906 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02619,381,741 - 19,463,028 (+)NCBIUU_Cfam_GSD_1.0
Sgsm1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405118115,728,506 - 115,807,723 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493665765,586 - 142,206 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936657109,232 - 142,195 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
SGSM1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1442,882,154 - 42,974,741 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11442,882,101 - 42,974,755 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21445,613,319 - 45,705,958 (+)NCBISscrofa10.2Sscrofa10.2susScr3
SGSM1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1197,906,444 - 8,024,484 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl197,906,657 - 8,024,488 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666045118,097,305 - 118,215,335 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Sgsm1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247472,114,562 - 2,206,060 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247472,113,259 - 2,205,718 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression

RNA-SEQ Expression


Sequence


Ensembl Acc Id: ENSPPAT00000027727   ⟹   ENSPPAP00000006447
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl2223,429,702 - 23,546,446 (+)Ensembl
Ensembl Acc Id: ENSPPAT00000027733   ⟹   ENSPPAP00000006449
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl2223,429,702 - 23,546,446 (+)Ensembl
Ensembl Acc Id: ENSPPAT00000027752   ⟹   ENSPPAP00000006454
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl2223,464,361 - 23,546,446 (+)Ensembl
Ensembl Acc Id: ENSPPAT00000027754   ⟹   ENSPPAP00000006456
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl2223,465,693 - 23,546,446 (+)Ensembl
Ensembl Acc Id: ENSPPAT00000027757   ⟹   ENSPPAP00000006457
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl2223,465,693 - 23,546,446 (+)Ensembl
RefSeq Acc Id: XM_034949038   ⟹   XP_034804929
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v22334,705,565 - 34,826,547 (+)NCBI
NHGRI_mPanPan12237,403,798 - 37,525,340 (+)NCBI
Mhudiblu_PPA_v0225,761,499 - 5,882,410 (+)NCBI
RefSeq Acc Id: XM_034949039   ⟹   XP_034804930
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v22334,705,565 - 34,826,547 (+)NCBI
NHGRI_mPanPan12237,403,798 - 37,525,340 (+)NCBI
Mhudiblu_PPA_v0225,761,495 - 5,882,410 (+)NCBI
Protein Sequences
Protein RefSeqs XP_034804929 (Get FASTA)   NCBI Sequence Viewer  
  XP_034804930 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSPPAP00000006447.1
  ENSPPAP00000006449.1
  ENSPPAP00000006454.1
  ENSPPAP00000006456.1
  ENSPPAP00000006457.1
RefSeq Acc Id: XP_034804930   ⟸   XM_034949039
- Peptide Label: isoform X2
- UniProtKB: A0A2R8ZU98 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_034804929   ⟸   XM_034949038
- Peptide Label: isoform X1
- UniProtKB: A0A2R8ZNB8 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSPPAP00000006449   ⟸   ENSPPAT00000027733
Ensembl Acc Id: ENSPPAP00000006447   ⟸   ENSPPAT00000027727
Ensembl Acc Id: ENSPPAP00000006457   ⟸   ENSPPAT00000027757
Ensembl Acc Id: ENSPPAP00000006456   ⟸   ENSPPAT00000027754
Ensembl Acc Id: ENSPPAP00000006454   ⟸   ENSPPAT00000027752
Protein Domains
Rab-GAP TBC   RUN


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSPPAG00000025023 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSPPAT00000027727.1 UniProtKB/TrEMBL
  ENSPPAT00000027733.1 UniProtKB/TrEMBL
  ENSPPAT00000027752.1 UniProtKB/TrEMBL
  ENSPPAT00000027754.1 UniProtKB/TrEMBL
  ENSPPAT00000027757.1 UniProtKB/TrEMBL
Gene3D-CATH 1.20.58.900 UniProtKB/TrEMBL
  2.30.29.230 UniProtKB/TrEMBL
  putative rabgap domain of human tbc1 domain family member 14 like domains UniProtKB/TrEMBL
  Ypt/Rab-GAP domain of gyp1p, domain 3 UniProtKB/TrEMBL
InterPro Rab-GTPase-TBC_dom UniProtKB/TrEMBL
  Rab-GTPase_TBC_sf UniProtKB/TrEMBL
  Run_dom UniProtKB/TrEMBL
  Run_dom_sf UniProtKB/TrEMBL
  RUN_SGSM1 UniProtKB/TrEMBL
  SGSM1/2 UniProtKB/TrEMBL
  SGSM1/2_RBD UniProtKB/TrEMBL
NCBI Gene SGSM1 ENTREZGENE
PANTHER SMALL G PROTEIN SIGNALING MODULATOR 1 UniProtKB/TrEMBL
  TBC1 DOMAIN FAMILY MEMBER GTPASE-ACTIVATING PROTEIN UniProtKB/TrEMBL
Pfam PH_RBD UniProtKB/TrEMBL
  RabGAP-TBC UniProtKB/TrEMBL
  RUN UniProtKB/TrEMBL
PROSITE RUN UniProtKB/TrEMBL
  TBC_RABGAP UniProtKB/TrEMBL
SMART RUN UniProtKB/TrEMBL
  TBC UniProtKB/TrEMBL
Superfamily-SCOP SSF140741 UniProtKB/TrEMBL
  SSF47923 UniProtKB/TrEMBL
UniProt A0A2R8ZNB8 ENTREZGENE, UniProtKB/TrEMBL
  A0A2R8ZNC4_PANPA UniProtKB/TrEMBL
  A0A2R8ZRB9_PANPA UniProtKB/TrEMBL
  A0A2R8ZU98 ENTREZGENE, UniProtKB/TrEMBL
  A0A2R8ZUB0_PANPA UniProtKB/TrEMBL