MYO1C (myosin IC) - Rat Genome Database

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Gene: MYO1C (myosin IC) Pan paniscus
Analyze
Symbol: MYO1C
Name: myosin IC
RGD ID: 11947820
Description: ENCODES a protein that exhibits actin filament binding (ortholog); calmodulin binding (ortholog); microfilament motor activity (ortholog); INVOLVED IN cellular response to type II interferon (ortholog); positive regulation of actin filament polymerization (ortholog); positive regulation of cellular response to insulin stimulus (ortholog); PARTICIPATES IN auditory mechanotransduction pathway; insulin responsive facilitative sugar transporter mediated glucose transport pathway; ASSOCIATED WITH atrial fibrillation (ortholog); Experimental Liver Cirrhosis (ortholog); genetic disease (ortholog); FOUND IN B-WICH complex (ortholog); ruffle membrane (ortholog); stereocilium bundle (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: unconventional myosin-Ic
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly
Position:
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2199,034,149 - 9,063,270 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11711,000,420 - 11,029,540 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0171,446,506 - 1,475,634 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1171,345,143 - 1,375,540 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl171,345,143 - 1,375,540 (-)Ensemblpanpan1.1panPan2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
MYO1C
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2199,034,149 - 9,063,270 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11711,000,420 - 11,029,540 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0171,446,506 - 1,475,634 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1171,345,143 - 1,375,540 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl171,345,143 - 1,375,540 (-)Ensemblpanpan1.1panPan2
MYO1C
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38171,464,186 - 1,492,686 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl171,464,186 - 1,492,686 (-)EnsemblGRCh38hg38GRCh38
GRCh37171,367,480 - 1,395,980 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36171,314,230 - 1,342,751 (-)NCBINCBI36Build 36hg18NCBI36
Build 34171,314,874 - 1,342,745NCBI
Celera171,382,666 - 1,411,498 (-)NCBICelera
Cytogenetic Map17p13.3NCBI
HuRef171,267,587 - 1,296,167 (-)NCBIHuRef
CHM1_1171,376,234 - 1,404,693 (-)NCBICHM1_1
T2T-CHM13v2.0171,352,909 - 1,381,443 (-)NCBIT2T-CHM13v2.0
Myo1c
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391175,541,345 - 75,565,450 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1175,541,330 - 75,564,736 (+)EnsemblGRCm39 Ensembl
GRCm381175,650,519 - 75,674,643 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1175,650,504 - 75,673,910 (+)EnsemblGRCm38mm10GRCm38
MGSCv371175,465,011 - 75,488,145 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361175,467,773 - 75,490,838 (+)NCBIMGSCv36mm8
Celera1183,160,567 - 83,183,742 (+)NCBICelera
Cytogenetic Map11B5NCBI
cM Map1145.92NCBI
Myo1c
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81060,996,642 - 61,019,022 (+)NCBIGRCr8
mRatBN7.21060,498,372 - 60,520,752 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1060,498,280 - 60,520,752 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1065,150,370 - 65,167,442 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01064,655,787 - 64,672,859 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01060,118,363 - 60,135,435 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01063,803,311 - 63,819,614 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1063,803,309 - 63,819,614 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01064,185,628 - 64,201,931 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41062,990,673 - 63,006,974 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11063,004,293 - 63,020,597 (+)NCBI
Celera1059,530,993 - 59,546,121 (+)NCBICelera
Cytogenetic Map10q24NCBI
Myo1c
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554811,676,728 - 1,703,488 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554811,676,788 - 1,701,421 (+)NCBIChiLan1.0ChiLan1.0
MYO1C
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1945,635,295 - 45,658,226 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl945,636,208 - 45,658,035 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha944,787,550 - 44,810,320 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0946,463,244 - 46,486,023 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl946,463,244 - 46,485,945 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1945,233,730 - 45,256,432 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0945,528,186 - 45,550,881 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0945,581,598 - 45,604,345 (-)NCBIUU_Cfam_GSD_1.0
Myo1c
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440560244,733,124 - 44,761,658 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365387,611,008 - 7,639,581 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365387,614,985 - 7,639,603 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
MYO1C
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1247,691,256 - 47,718,337 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11247,691,252 - 47,715,670 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21249,785,597 - 49,802,342 (-)NCBISscrofa10.2Sscrofa10.2susScr3
MYO1C
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1161,137,469 - 1,167,497 (-)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366605920,819,456 - 20,849,629 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Myo1c
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247864,188,143 - 4,211,732 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247864,188,143 - 4,211,712 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSPPAT00000029041   ⟹   ENSPPAP00000007044
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl171,345,143 - 1,375,540 (-)Ensembl
RefSeq Acc Id: ENSPPAT00000029046   ⟹   ENSPPAP00000007046
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl171,345,143 - 1,369,253 (-)Ensembl
RefSeq Acc Id: ENSPPAT00000029054   ⟹   ENSPPAP00000007053
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl171,346,682 - 1,372,370 (-)Ensembl
RefSeq Acc Id: ENSPPAT00000029060   ⟹   ENSPPAP00000007058
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl171,346,682 - 1,368,855 (-)Ensembl
RefSeq Acc Id: XM_003816837   ⟹   XP_003816885
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2199,034,149 - 9,063,270 (-)NCBI
NHGRI_mPanPan11711,000,420 - 11,029,540 (-)NCBI
Mhudiblu_PPA_v0171,446,506 - 1,475,634 (-)NCBI
PanPan1.1171,345,143 - 1,375,540 (-)NCBI
Sequence:
RefSeq Acc Id: XM_034941221   ⟹   XP_034797112
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2199,034,149 - 9,056,385 (-)NCBI
NHGRI_mPanPan11711,000,420 - 11,022,611 (-)NCBI
Mhudiblu_PPA_v0171,446,506 - 1,468,699 (-)NCBI
RefSeq Acc Id: XM_034941222   ⟹   XP_034797113
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2199,034,149 - 9,062,279 (-)NCBI
NHGRI_mPanPan11711,000,420 - 11,028,549 (-)NCBI
Mhudiblu_PPA_v0171,446,506 - 1,474,643 (-)NCBI
RefSeq Acc Id: XM_063598840   ⟹   XP_063454910
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2199,036,875 - 9,056,385 (-)NCBI
Reference Protein Sequences
RefSeq Acc Id: XP_003816885   ⟸   XM_003816837
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: XP_034797113   ⟸   XM_034941222
- Peptide Label: isoform X4
RefSeq Acc Id: XP_034797112   ⟸   XM_034941221
- Peptide Label: isoform X3
RefSeq Acc Id: ENSPPAP00000007044   ⟸   ENSPPAT00000029041
RefSeq Acc Id: ENSPPAP00000007046   ⟸   ENSPPAT00000029046
RefSeq Acc Id: ENSPPAP00000007058   ⟸   ENSPPAT00000029060
RefSeq Acc Id: ENSPPAP00000007053   ⟸   ENSPPAT00000029054
RefSeq Acc Id: XP_063454910   ⟸   XM_063598840
- Peptide Label: isoform X1
Protein Domains
Myosin motor   TH1


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSPPAG00000025962 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSPPAT00000029041.1 UniProtKB/TrEMBL
  ENSPPAT00000029046.1 UniProtKB/TrEMBL
  ENSPPAT00000029054.1 UniProtKB/TrEMBL
  ENSPPAT00000029060.1 UniProtKB/TrEMBL
Gene3D-CATH 1.10.10.820 UniProtKB/TrEMBL
  1.20.5.190 UniProtKB/TrEMBL
  1.20.58.530 UniProtKB/TrEMBL
  3.40.850.10 UniProtKB/TrEMBL
  6.20.240.20 UniProtKB/TrEMBL
  Myosin VI head, motor domain, U50 subdomain UniProtKB/TrEMBL
InterPro IQ_motif_EF-hand-BS UniProtKB/TrEMBL
  Kinesin_motor_dom_sf UniProtKB/TrEMBL
  Myosin_head_motor_dom UniProtKB/TrEMBL
  Myosin_TH1 UniProtKB/TrEMBL
  MYSc_Myo1 UniProtKB/TrEMBL
  P-loop_NTPase UniProtKB/TrEMBL
KEGG Report pps:100975993 UniProtKB/TrEMBL
NCBI Gene MYO1C ENTREZGENE
PANTHER MYOSIN UniProtKB/TrEMBL
  UNCONVENTIONAL MYOSIN-IC UniProtKB/TrEMBL
Pfam Myosin_head UniProtKB/TrEMBL
  Myosin_TH1 UniProtKB/TrEMBL
  PF00612 UniProtKB/TrEMBL
PRINTS MYOSINHEAVY UniProtKB/TrEMBL
PROSITE MYOSIN_MOTOR UniProtKB/TrEMBL
  PS50096 UniProtKB/TrEMBL
  TH1 UniProtKB/TrEMBL
SMART MYSc UniProtKB/TrEMBL
  SM00015 UniProtKB/TrEMBL
Superfamily-SCOP SSF52540 UniProtKB/TrEMBL
UniProt A0A2R8ZQ29_PANPA UniProtKB/TrEMBL
  A0A2R8ZT44_PANPA UniProtKB/TrEMBL
  A0A2R8ZT49_PANPA UniProtKB/TrEMBL
  A0A2R8ZVX3_PANPA UniProtKB/TrEMBL