NOP58 (NOP58 ribonucleoprotein) - Rat Genome Database

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Gene: NOP58 (NOP58 ribonucleoprotein) Pan paniscus
Analyze
Symbol: NOP58
Name: NOP58 ribonucleoprotein
RGD ID: 11918844
Description: ENCODES a protein that exhibits ATPase binding (inferred); snoRNA binding (inferred); TFIID-class transcription factor complex binding (inferred); INVOLVED IN ribosomal small subunit biogenesis (inferred); ribosome biogenesis (inferred); snoRNA localization (inferred); PARTICIPATES IN ribosome biogenesis pathway; ASSOCIATED WITH Animal Disease Models (ortholog); autoimmune lymphoproliferative syndrome type 2B (ortholog); Autoimmune Lymphoproliferative Syndrome, Type V (ortholog); FOUND IN box C/D methylation guide snoRNP complex (inferred); Cajal body (inferred); cytosol (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: NOP58 ribonucleoprotein homolog; nucleolar protein 58
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly
Position:
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v213104,890,221 - 104,928,093 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12B104,905,239 - 104,943,091 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02B89,520,961 - 89,558,794 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12B207,674,433 - 207,707,763 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2B207,674,654 - 207,707,763 (+)Ensemblpanpan1.1panPan2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
NOP58Bonoboautoimmune lymphoproliferative syndrome type 2B  ISONOP58 (Homo sapiens)8554872ClinVar Annotator: match by term: Autoimmune lymphoproliferative syndrome type 2BClinVarPMID:11343122 more ...
NOP58BonoboAutoimmune Lymphoproliferative Syndrome, Type V  ISONOP58 (Homo sapiens)8554872ClinVar Annotator: match by term: Autoimmune lymphoproliferative syndrome type VClinVarPMID:11343122 more ...
NOP58Bonobocommon variable immunodeficiency 1  ISONOP58 (Homo sapiens)8554872ClinVar Annotator: match by term: Immunodeficiency more ...ClinVarPMID:11343122 more ...
NOP58BonoboNeurodevelopmental Disorders  ISONOP58 (Homo sapiens)8554872ClinVar Annotator: match by term: Neurodevelopmental disorderClinVarPMID:25741868
NOP58Bonoboprimary pulmonary hypertension  ISONOP58 (Homo sapiens)8554872ClinVar Annotator: match by term: Primary pulmonary hypertensionClinVarPMID:16429395 more ...
NOP58Bonoboprimary pulmonary hypertension 1  ISONOP58 (Homo sapiens)8554872ClinVar Annotator: match by term: Pulmonary hypertension more ...ClinVarPMID:23579436
NOP58BonoboPulmonary Arterial Hypertension  ISONOP58 (Homo sapiens)8554872ClinVar Annotator: match by term: Pulmonary arterial hypertensionClinVarPMID:32581362
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
NOP58BonoboAnimal Disease Models  ISONOP58 (Homo sapiens)9068941CTD Direct Evidence: marker/mechanismCTDPMID:27602772
NOP58Bonobolung adenocarcinoma  ISONOP58 (Homo sapiens)9068941CTD Direct Evidence: marker/mechanismCTDPMID:27602772


Biological Process

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
NOP58Bonoboribosomal small subunit biogenesis involved_inIEAUniProtKB:Q9Y2X3 and ensembl:ENSP00000264279150520179 EnsemblGO_REF:0000107
NOP58Bonoboribosome biogenesis involved_inIEAUniProtKB-KW:KW-0690150520179 UniProtGO_REF:0000043
NOP58BonobosnoRNA localization involved_inIEAUniProtKB:Q9Y2X3 and ensembl:ENSP00000264279150520179 EnsemblGO_REF:0000107

Cellular Component
1 to 16 of 16 rows

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
NOP58Bonobobox C/D methylation guide snoRNP complex part_ofIEAInterPro:IPR045056150520179 InterProGO_REF:0000002
NOP58Bonobobox C/D methylation guide snoRNP complex part_ofIEAPANTHER:PTN000096035 and PANTHER:PTN000096041150520179 TreeGrafterGO_REF:0000118
NOP58Bonobobox C/D methylation guide snoRNP complex part_ofIEAUniProtKB:Q9Y2X3 and ensembl:ENSP00000264279150520179 EnsemblGO_REF:0000107
NOP58BonoboCajal body located_inIEAUniProtKB:Q9Y2X3 and ensembl:ENSP00000264279150520179 EnsemblGO_REF:0000107
NOP58Bonobocytosol located_inIEAUniProtKB:Q9Y2X3 and ensembl:ENSP00000264279150520179 EnsemblGO_REF:0000107
NOP58Bonobofibrillar center located_inIEAUniProtKB:Q9Y2X3 and ensembl:ENSP00000264279150520179 EnsemblGO_REF:0000107
NOP58Bonobonucleolus located_inIEAUniProtKB:Q9Y2X3 and ensembl:ENSP00000264279150520179 EnsemblGO_REF:0000107
NOP58Bonobonucleolus located_inIEAUniProtKB-SubCell:SL-0188150520179 UniProtGO_REF:0000044
NOP58Bonobonucleoplasm located_inIEAUniProtKB-SubCell:SL-0190150520179 UniProtGO_REF:0000044
NOP58Bonobonucleoplasm located_inIEAUniProtKB:Q9Y2X3 and ensembl:ENSP00000264279150520179 EnsemblGO_REF:0000107
NOP58Bonobonucleus located_inIEAUniProtKB-KW:KW-0539150520179 UniProtGO_REF:0000043
NOP58Bonobopre-snoRNP complex part_ofIEAUniProtKB:Q9Y2X3 and ensembl:ENSP00000264279150520179 EnsemblGO_REF:0000107
NOP58Bonobosmall-subunit processome part_ofIEAUniProtKB:Q9Y2X3 and ensembl:ENSP00000264279150520179 EnsemblGO_REF:0000107
NOP58Bonobosmall-subunit processome part_ofIEAInterPro:IPR045056150520179 InterProGO_REF:0000002
NOP58Bonobosmall-subunit processome part_ofIEAPANTHER:PTN000096035 and PANTHER:PTN000096041150520179 TreeGrafterGO_REF:0000118
NOP58Bonobosno(s)RNA-containing ribonucleoprotein complex part_ofIEAUniProtKB:Q9Y2X3 and ensembl:ENSP00000264279150520179 EnsemblGO_REF:0000107
1 to 16 of 16 rows

Molecular Function
1 to 13 of 13 rows

  
1 to 13 of 13 rows

RGD Manual Annotations


  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
NOP58Bonoboribosome biogenesis pathway   ISONOP58 (Homo sapiens)9068941 RGDPMID:22065625 and REF_RGD_ID:9999451
PMID:30032202  



NOP58
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v213104,890,221 - 104,928,093 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12B104,905,239 - 104,943,091 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02B89,520,961 - 89,558,794 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12B207,674,433 - 207,707,763 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2B207,674,654 - 207,707,763 (+)Ensemblpanpan1.1panPan2
NOP58
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382202,265,763 - 202,303,661 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2202,265,736 - 202,303,661 (+)EnsemblGRCh38hg38GRCh38
GRCh372203,130,486 - 203,168,384 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 362202,838,760 - 202,876,629 (+)NCBINCBI36Build 36hg18NCBI36
Build 342202,956,020 - 202,993,888NCBI
Celera2196,882,417 - 196,920,291 (+)NCBICelera
Cytogenetic Map2q33.1NCBI
HuRef2194,979,023 - 195,015,805 (+)NCBIHuRef
CHM1_12203,136,987 - 203,174,808 (+)NCBICHM1_1
T2T-CHM13v2.02202,746,796 - 202,784,682 (+)NCBIT2T-CHM13v2.0
Nop58
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39159,724,165 - 59,751,352 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl159,724,130 - 59,758,203 (+)EnsemblGRCm39 Ensembl
GRCm38159,684,961 - 59,711,510 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl159,684,971 - 59,719,044 (+)EnsemblGRCm38mm10GRCm38
MGSCv37159,741,850 - 59,768,354 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36159,629,645 - 59,656,054 (+)NCBIMGSCv36mm8
Celera160,199,706 - 60,226,206 (+)NCBICelera
Cytogenetic Map1C2NCBI
cM Map130.38NCBI
Nop58
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8968,614,992 - 68,638,911 (+)NCBIGRCr8
mRatBN7.2961,120,939 - 61,144,810 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl961,120,929 - 61,144,810 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx969,615,623 - 69,639,722 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0974,731,599 - 74,755,698 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0973,049,892 - 73,073,989 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0966,495,881 - 66,520,521 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl966,495,832 - 66,519,788 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0966,300,036 - 66,323,766 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4958,255,685 - 58,279,522 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1958,402,666 - 58,426,502 (+)NCBI
Celera958,555,582 - 58,579,638 (+)NCBICelera
Cytogenetic Map9q31NCBI
Nop58
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495545712,479,965 - 12,511,678 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495545712,481,467 - 12,511,678 (-)NCBIChiLan1.0ChiLan1.0
NOP58
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.13711,255,562 - 11,287,325 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl3711,255,589 - 11,287,279 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha3712,138,970 - 12,170,731 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.03711,191,615 - 11,223,536 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl3711,191,646 - 11,223,757 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.13711,142,546 - 11,173,876 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.03711,121,045 - 11,152,921 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.03711,114,468 - 11,146,228 (+)NCBIUU_Cfam_GSD_1.0
Nop58
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405303159,486,721 - 159,517,681 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049367261,457,002 - 1,486,530 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049367261,457,038 - 1,487,374 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
NOP58
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl15105,893,637 - 105,930,459 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.115105,893,589 - 105,930,458 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.215117,351,116 - 117,380,896 (+)NCBISscrofa10.2Sscrofa10.2susScr3
NOP58
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11087,989,687 - 88,026,774 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1087,989,699 - 88,026,904 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666040111,362,208 - 111,399,710 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Nop58
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462476514,139,815 - 14,172,413 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

.






Ensembl Acc Id: ENSPPAT00000049959   ⟹   ENSPPAP00000027122
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl2B207,674,654 - 207,707,240 (+)Ensembl
Ensembl Acc Id: ENSPPAT00000049963   ⟹   ENSPPAP00000027125
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl2B207,674,654 - 207,704,500 (+)Ensembl
Ensembl Acc Id: ENSPPAT00000049964   ⟹   ENSPPAP00000027126
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl2B207,674,654 - 207,682,201 (+)Ensembl
Ensembl Acc Id: ENSPPAT00000049966   ⟹   ENSPPAP00000027128
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl2B207,679,294 - 207,707,763 (+)Ensembl
RefSeq Acc Id: XM_003820765   ⟹   XP_003820813
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v213104,890,221 - 104,928,093 (+)NCBI
NHGRI_mPanPan12B104,905,239 - 104,943,091 (+)NCBI
Mhudiblu_PPA_v02B89,520,965 - 89,558,794 (+)NCBI
PanPan1.12B207,674,433 - 207,707,763 (+)NCBI
Sequence:
RefSeq Acc Id: XM_034954817   ⟹   XP_034810708
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v213104,894,148 - 104,928,093 (+)NCBI
NHGRI_mPanPan12B104,905,264 - 104,943,091 (+)NCBI
Mhudiblu_PPA_v02B89,520,965 - 89,558,794 (+)NCBI
RefSeq Acc Id: XM_034954818   ⟹   XP_034810709
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v213104,899,640 - 104,928,093 (+)NCBI
NHGRI_mPanPan12B104,914,638 - 104,943,091 (+)NCBI
Mhudiblu_PPA_v02B89,530,350 - 89,558,794 (+)NCBI
RefSeq Acc Id: XM_034954820   ⟹   XP_034810711
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v213104,890,250 - 104,924,798 (+)NCBI
NHGRI_mPanPan12B104,905,248 - 104,939,796 (+)NCBI
Mhudiblu_PPA_v02B89,520,961 - 89,555,485 (+)NCBI
RefSeq Acc Id: XR_004670277
Type: NON-CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v213104,890,250 - 104,924,798 (+)NCBI
NHGRI_mPanPan12B104,905,248 - 104,939,759 (+)NCBI
Mhudiblu_PPA_v02B89,520,961 - 89,555,440 (+)NCBI
Protein RefSeqs XP_003820813 (Get FASTA)   NCBI Sequence Viewer  
  XP_034810708 (Get FASTA)   NCBI Sequence Viewer  
  XP_034810709 (Get FASTA)   NCBI Sequence Viewer  
  XP_034810711 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSPPAP00000027122.1
  ENSPPAP00000027125.1
  ENSPPAP00000027126.1
  ENSPPAP00000027128.1
RefSeq Acc Id: XP_003820813   ⟸   XM_003820765
- Peptide Label: isoform X1
- UniProtKB: A0A2R9BD92 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_034810711   ⟸   XM_034954820
- Peptide Label: isoform X4
- UniProtKB: A0A2R9BK57 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_034810708   ⟸   XM_034954817
- Peptide Label: isoform X2
- UniProtKB: A0A2R9BBX4 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_034810709   ⟸   XM_034954818
- Peptide Label: isoform X3
Ensembl Acc Id: ENSPPAP00000027122   ⟸   ENSPPAT00000049959


1 to 25 of 25 rows
Database
Acc Id
Source(s)
Ensembl Genes ENSPPAG00000036626 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSPPAT00000049959.1 UniProtKB/TrEMBL
  ENSPPAT00000049963.1 UniProtKB/TrEMBL
  ENSPPAT00000049964.1 UniProtKB/TrEMBL
  ENSPPAT00000049966.1 UniProtKB/TrEMBL
Gene3D-CATH 1.10.246.90 UniProtKB/TrEMBL
  1.10.287.4070 UniProtKB/TrEMBL
InterPro Nop56/Nop58 UniProtKB/TrEMBL
  NOP5_N UniProtKB/TrEMBL
  Nop_C UniProtKB/TrEMBL
  Nop_dom UniProtKB/TrEMBL
  Nop_dom_sf UniProtKB/TrEMBL
  NOSIC UniProtKB/TrEMBL
NCBI Gene NOP58 ENTREZGENE
PANTHER NUCLEOLAR PROTEIN 58 UniProtKB/TrEMBL
  PTHR10894 UniProtKB/TrEMBL
Pfam Nop UniProtKB/TrEMBL
  NOP5NT UniProtKB/TrEMBL
PROSITE NOP UniProtKB/TrEMBL
SMART NOSIC UniProtKB/TrEMBL
Superfamily-SCOP SSF89124 UniProtKB/TrEMBL
UniProt A0A2R9BBX4 ENTREZGENE, UniProtKB/TrEMBL
  A0A2R9BD92 ENTREZGENE, UniProtKB/TrEMBL
  A0A2R9BFR1_PANPA UniProtKB/TrEMBL
  A0A2R9BK57 ENTREZGENE, UniProtKB/TrEMBL
1 to 25 of 25 rows