Symbol:
NR5A1
Name:
nuclear receptor subfamily 5 group A member 1
RGD ID:
11863641
Description:
ENCODES a protein that exhibits DNA-binding transcription factor activity (ortholog); double-stranded DNA binding (ortholog); sequence-specific DNA binding (ortholog); INVOLVED IN calcineurin-mediated signaling (ortholog); female gonad development (ortholog); hormone-mediated signaling pathway (ortholog); ASSOCIATED WITH 46 XX gonadal dysgenesis (ortholog); 46, XY Disorders of Sex Development (ortholog); 46,XX sex reversal 4 (ortholog); FOUND IN cytoplasm (inferred); cytosol (inferred); nucleoplasm (inferred)
Type:
protein-coding
RefSeq Status:
MODEL
Previously known as:
steroidogenic factor 1
RGD Orthologs
Alliance Orthologs
More Info
more info ...
More Info
Latest Assembly:
Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly
Position:
Bonobo Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl NHGRI_mPanPan1-v2 11 14,852,025 - 14,874,137 (+) NCBI NHGRI_mPanPan1-v2 NHGRI_mPanPan1 9 14,854,371 - 14,875,019 (+) NCBI NHGRI_mPanPan1 Mhudiblu_PPA_v0 9 95,605,282 - 95,628,773 (-) NCBI Mhudiblu_PPA_v0 Mhudiblu_PPA_v0 panPan3 PanPan1.1 9 124,122,968 - 124,149,292 (-) NCBI panpan1.1 PanPan1.1 panPan2 PanPan1.1 Ensembl 9 124,122,968 - 124,149,292 (-) Ensembl panpan1.1 panPan2
JBrowse:
View Region in Genome Browser (JBrowse)
Model
NR5A1 Bonobo 46, XY Disorders of Sex Development ISO RGD:68493 8554872 ClinVar Annotator: match by term: 46,XY disorder of sex development ClinVar PMID:17694559|PMID:20887963|PMID:25741868|PMID:25989977|PMID:26260161|PMID:27899157|PMID:28492532|PMID:29265478|PMID:30425642|PMID:31513305 NR5A1 Bonobo 46,XX sex reversal 4 ISO RGD:68493 8554872 ClinVar Annotator: match by term: 46,XX sex reversal 4 ClinVar PMID:11932325|PMID:22549935|PMID:25741868|PMID:26523528|PMID:27378692|PMID:27490115|PMID:27610946|PMID:27855412|PMID:28033660|PMID:28492532 NR5A1 Bonobo 46,XY sex reversal 3 ISO RGD:68493 8554872 ClinVar Annotator: match by term: 46,XY sex reversal 3 | ClinVar Annotator: match by term: more ... ClinVar PMID:11932325|PMID:15070943|PMID:15472171|PMID:15579739|PMID:17200175|PMID:17576681|PMID:17694559|PMID:18414213|PMID:19246354|PMID:20887963|PMID:21691958|PMID:22028768|PMID:22474171|PMID:22549935|PMID:25122490|PMID:25326637|PMID:25741868|PMID:25989977|PMID:26523528|PMID:27169744|PMID:27378692|PMID:27490115|PMID:27610946|PMID:27855412|PMID:27899157|PMID:28033660|PMID:28492532|PMID:29095814|PMID:29935645|PMID:30425642|PMID:31513305|PMID:31745530|PMID:31852928|PMID:32738419|PMID:33202802|PMID:33351340|PMID:35432193|PMID:35690514|PMID:35935368|PMID:36572623|PMID:38128121|PMID:9536098 NR5A1 Bonobo disorder of sexual development ISO RGD:68493 8554872 ClinVar Annotator: match by term: Disorder of sexual differentiation ClinVar PMID:25741868|PMID:28492532|PMID:31513305|PMID:31852928|PMID:35432193|PMID:35935368 NR5A1 Bonobo genetic disease ISO RGD:68493 8554872 ClinVar Annotator: match by term: Inborn genetic diseases ClinVar PMID:28492532 NR5A1 Bonobo hereditary breast ovarian cancer syndrome ISO RGD:68493 8554872 ClinVar Annotator: match by term: Genetic non-acquired premature ovarian failure ClinVar PMID:25741868|PMID:28492532 NR5A1 Bonobo hereditary breast ovarian cancer syndrome ISO RGD:68493 8554872 ClinVar Annotator: match by term: Genetic non-acquired premature ovarian failure | ClinVar Annotator: match by more ... ClinVar PMID:22028768|PMID:22907560|PMID:25122490|PMID:25741868|PMID:27169744|PMID:28492532|PMID:30425642 NR5A1 Bonobo hereditary breast ovarian cancer syndrome ISO RGD:68493 8554872 ClinVar Annotator: match by term: Genetic non-acquired premature ovarian failure | ClinVar Annotator: match by more ... ClinVar PMID:22028768|PMID:22907560|PMID:23154282|PMID:25122490|PMID:25383892|PMID:25741868|PMID:27169744|PMID:28492532 NR5A1 Bonobo male infertility ISO RGD:68493 8554872 ClinVar Annotator: match by term: Male infertility ClinVar PMID:17940071|PMID:20887963|PMID:25741868|PMID:25989977|PMID:28492532|PMID:29935645|PMID:30067310|PMID:32655042|PMID:35690514|PMID:36572623 NR5A1 Bonobo primary ovarian insufficiency 16 ISO RGD:68493 8554872 ClinVar Annotator: match by term: Genetic non-acquired premature ovarian failure ClinVar PMID:22028768|PMID:22907560|PMID:25122490|PMID:25741868|PMID:27169744|PMID:28492532|PMID:30425642 NR5A1 Bonobo primary ovarian insufficiency 7 ISO RGD:68493 8554872 ClinVar Annotator: match by term: ADRENAL INSUFFICIENCY, NR5A1-RELATED | ClinVar Annotator: match by term: Premature more ... ClinVar PMID:11038323|PMID:11932325|PMID:17940071|PMID:19246354|PMID:25741868|PMID:26523528|PMID:27855412|PMID:28492532|PMID:30067310|PMID:32655042|PMID:34008892|PMID:36572623 NR5A1 Bonobo spermatogenic failure 1 ISO RGD:68493 8554872 ClinVar Annotator: match by term: Oligosynaptic infertility ClinVar PMID:10369247|PMID:11038323|PMID:12907682|PMID:16199547|PMID:17576681|PMID:17694559|PMID:17940071|PMID:19246354|PMID:19269353|PMID:19439508|PMID:20887963|PMID:22028768|PMID:22100173|PMID:22474171|PMID:22549935|PMID:22907560|PMID:23543655|PMID:23729601|PMID:24591553|PMID:25122490|PMID:25741868|PMID:25989977|PMID:27169744|PMID:27378692|PMID:27490115|PMID:27610946|PMID:27899157|PMID:28032338|PMID:28033660|PMID:28130116|PMID:28326187|PMID:28492532|PMID:28938747|PMID:29027299|PMID:29095814|PMID:29190620|PMID:29265478|PMID:29582157|PMID:29935645|PMID:30067310|PMID:30406445|PMID:30425642|PMID:31513305|PMID:31831369|PMID:32008008|PMID:32655042|PMID:32738419|PMID:32985417|PMID:33351340|PMID:34095689|PMID:34461970|PMID:35690514|PMID:36572623|PMID:36745277|PMID:38128121|PMID:9536098 NR5A1 Bonobo spermatogenic failure 3 ISO RGD:68493 8554872 ClinVar Annotator: match by term: Non-obstructive azoospermia ClinVar PMID:18414213|PMID:20887963|PMID:25741868|PMID:25989977|PMID:28492532|PMID:35690514|PMID:36572623 NR5A1 Bonobo spermatogenic failure 57 ISO RGD:68493 8554872 ClinVar Annotator: match by term: Male infertility with azoospermia or oligozoospermia due to single gene more ... ClinVar PMID:10369247|PMID:11038323|PMID:12907682|PMID:19246354|PMID:20887963|PMID:22100173|PMID:23543655|PMID:25741868|PMID:28492532 NR5A1 Bonobo spermatogenic failure 8 ISO RGD:68493 8554872 ClinVar Annotator: match by term: Spermatogenic failure 8 ClinVar PMID:20887963|PMID:25741868|PMID:25989977|PMID:28492532|PMID:35690514|PMID:36572623
NR5A1 (Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl NHGRI_mPanPan1-v2 11 14,852,025 - 14,874,137 (+) NCBI NHGRI_mPanPan1-v2 NHGRI_mPanPan1 9 14,854,371 - 14,875,019 (+) NCBI NHGRI_mPanPan1 Mhudiblu_PPA_v0 9 95,605,282 - 95,628,773 (-) NCBI Mhudiblu_PPA_v0 Mhudiblu_PPA_v0 panPan3 PanPan1.1 9 124,122,968 - 124,149,292 (-) NCBI panpan1.1 PanPan1.1 panPan2 PanPan1.1 Ensembl 9 124,122,968 - 124,149,292 (-) Ensembl panpan1.1 panPan2
NR5A1 (Homo sapiens - human)
Human Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl GRCh38 9 124,481,236 - 124,507,399 (-) NCBI GRCh38 GRCh38 hg38 GRCh38 GRCh38.p14 Ensembl 9 124,481,236 - 124,507,420 (-) Ensembl GRCh38 hg38 GRCh38 GRCh37 9 127,243,515 - 127,269,678 (-) NCBI GRCh37 GRCh37 hg19 GRCh37 Build 36 9 126,283,336 - 126,309,520 (-) NCBI NCBI36 Build 36 hg18 NCBI36 Build 34 9 124,323,069 - 124,349,253 NCBI Celera 9 97,890,732 - 97,916,915 (-) NCBI Celera Cytogenetic Map 9 q33.3 NCBI HuRef 9 96,856,059 - 96,882,213 (-) NCBI HuRef CHM1_1 9 127,392,508 - 127,418,653 (-) NCBI CHM1_1 T2T-CHM13v2.0 9 136,679,465 - 136,705,624 (-) NCBI T2T-CHM13v2.0
Nr5a1 (Mus musculus - house mouse)
Mouse Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl GRCm39 2 38,582,668 - 38,604,554 (-) NCBI GRCm39 GRCm39 mm39 GRCm39 Ensembl 2 38,582,668 - 38,604,554 (-) Ensembl GRCm39 Ensembl GRCm38 2 38,692,656 - 38,714,542 (-) NCBI GRCm38 GRCm38 mm10 GRCm38 GRCm38.p6 Ensembl 2 38,692,656 - 38,714,542 (-) Ensembl GRCm38 mm10 GRCm38 MGSCv37 2 38,548,180 - 38,570,062 (-) NCBI GRCm37 MGSCv37 mm9 NCBIm37 MGSCv36 2 38,514,636 - 38,536,512 (-) NCBI MGSCv36 mm8 Celera 2 40,416,849 - 40,438,726 (-) NCBI Celera Cytogenetic Map 2 B NCBI cM Map 2 24.42 NCBI
Nr5a1 (Rattus norvegicus - Norway rat)
Rat Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl GRCr8 3 42,874,505 - 42,896,109 (-) NCBI GRCr8 mRatBN7.2 3 22,464,786 - 22,486,328 (-) NCBI mRatBN7.2 mRatBN7.2 mRatBN7.2 Ensembl 3 22,465,502 - 22,486,328 (-) Ensembl mRatBN7.2 Ensembl UTH_Rnor_SHR_Utx 3 25,933,801 - 25,954,690 (-) NCBI Rnor_SHR UTH_Rnor_SHR_Utx UTH_Rnor_SHRSP_BbbUtx_1.0 3 34,518,798 - 34,539,688 (-) NCBI Rnor_SHRSP UTH_Rnor_SHRSP_BbbUtx_1.0 UTH_Rnor_WKY_Bbb_1.0 3 32,331,170 - 32,351,980 (-) NCBI Rnor_WKY UTH_Rnor_WKY_Bbb_1.0 Rnor_6.0 3 22,998,900 - 23,020,441 (-) NCBI Rnor6.0 Rnor_6.0 rn6 Rnor6.0 Rnor_6.0 Ensembl 3 22,999,616 - 23,020,441 (-) Ensembl Rnor6.0 rn6 Rnor6.0 Rnor_5.0 3 28,223,427 - 28,244,968 (-) NCBI Rnor5.0 Rnor_5.0 rn5 Rnor5.0 RGSC_v3.4 3 18,498,913 - 18,519,738 (-) NCBI RGSC3.4 RGSC_v3.4 rn4 RGSC3.4 RGSC_v3.1 3 18,395,933 - 18,412,441 (-) NCBI Celera 3 20,898,726 - 20,919,551 (-) NCBI Celera Cytogenetic Map 3 q12 NCBI
Nr5a1 (Chinchilla lanigera - long-tailed chinchilla)
Chinchilla Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl ChiLan1.0 Ensembl NW_004955419 3,632,220 - 3,654,375 (+) Ensembl ChiLan1.0 ChiLan1.0 NW_004955419 3,632,248 - 3,654,367 (+) NCBI ChiLan1.0 ChiLan1.0
Nr5a1 (Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl HiC_Itri_2 NW_024404947 192,970,909 - 193,007,215 (-) NCBI HiC_Itri_2 SpeTri2.0 Ensembl NW_004936487 12,739,439 - 12,763,734 (-) Ensembl SpeTri2.0 SpeTri2.0 Ensembl SpeTri2.0 NW_004936487 12,739,445 - 12,763,729 (-) NCBI SpeTri2.0 SpeTri2.0 SpeTri2.0
NR5A1 (Sus scrofa - pig)
Pig Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl Sscrofa11.1 Ensembl 1 265,284,493 - 265,311,417 (-) Ensembl Sscrofa11.1 susScr11 Sscrofa11.1 Sscrofa11.1 1 265,284,491 - 265,311,547 (-) NCBI Sscrofa11.1 Sscrofa11.1 susScr11 Sscrofa11.1 Sscrofa10.2 1 299,123,683 - 299,135,326 (+) NCBI Sscrofa10.2 Sscrofa10.2 susScr3 Pig Cytomap 1 q210-q211 NCBI
NR5A1 (Chlorocebus sabaeus - green monkey)
Green Monkey Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl ChlSab1.1 12 13,640,453 - 13,666,748 (+) NCBI ChlSab1.1 ChlSab1.1 chlSab2 ChlSab1.1 Ensembl 12 13,640,473 - 13,666,863 (+) Ensembl ChlSab1.1 ChlSab1.1 Ensembl chlSab2 Vero_WHO_p1.0 NW_023666079 2,411,630 - 2,438,042 (-) NCBI Vero_WHO_p1.0 Vero_WHO_p1.0
Nr5a1 (Heterocephalus glaber - naked mole-rat)
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Click on a value in the shaded box below the category label to view a detailed expression data table for that system.
Ensembl Acc Id:
ENSPPAT00000044039 ⟹ ENSPPAP00000021239
Type:
CODING
Position:
Bonobo Assembly Chr Position (strand) Source PanPan1.1 Ensembl 9 124,122,968 - 124,149,292 (-) Ensembl
Ensembl Acc Id:
ENSPPAT00000044044 ⟹ ENSPPAP00000021243
Type:
CODING
Position:
Bonobo Assembly Chr Position (strand) Source PanPan1.1 Ensembl 9 124,124,445 - 124,145,123 (-) Ensembl
RefSeq Acc Id:
XM_034929032 ⟹ XP_034784923
Type:
CODING
Position:
Bonobo Assembly Chr Position (strand) Source NHGRI_mPanPan1-v2 11 14,852,025 - 14,874,137 (+) NCBI NHGRI_mPanPan1 9 14,854,371 - 14,875,019 (+) NCBI Mhudiblu_PPA_v0 9 95,605,282 - 95,628,773 (-) NCBI
RefSeq Acc Id:
XP_034784923 ⟸ XM_034929032
- UniProtKB:
A0A2R9B1E3 (UniProtKB/TrEMBL), A0A2R9AVM2 (UniProtKB/TrEMBL)
Ensembl Acc Id:
ENSPPAP00000021239 ⟸ ENSPPAT00000044039
Ensembl Acc Id:
ENSPPAP00000021243 ⟸ ENSPPAT00000044044