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Gene: Nr5a1 (nuclear receptor subfamily 5, group A, member 1) Mus musculus
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Symbol: Nr5a1
Name: nuclear receptor subfamily 5, group A, member 1
Description: Exhibits RNA polymerase II distal enhancer sequence-specific DNA binding activity and chromatin binding activity. Involved in several processes, including adrenal gland development; gonad development; and regulation of gonad development. Localizes to the RNA polymerase II transcription factor complex. Used to study hypogonadotropic hypogonadism. Human ortholog(s) of this gene implicated in 46 XY gonadal dysgenesis; Zellweger syndrome; premature ovarian failure; and spermatogenic failure 8. Is expressed in several structures, including central nervous system; endocrine gland; genitourinary system; hemolymphoid system; and respiratory system. Orthologous to human NR5A1 (nuclear receptor subfamily 5 group A member 1); INTERACTS WITH 17alpha-ethynylestradiol; 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: Ad4BP; adrenal 4-binding protein; ELP; ELP-3; embryonal long terminal repeat-binding protein; embryonal LTR-binding protein; Ftz-F1; Ftzf1; fushi tarazu 1 factor homolog; fushi tarazu factor homolog 1; MGC124277; MGC124278; nuclear receptor subfamily 5 group A member 1; SF-1; SF1; steroid hormone receptor Ad4BP; steroid hydroxylase positive regulator; steroidogenic factor 1; STF-1
Orthologs:
Homo sapiens (human) : NR5A1 (nuclear receptor subfamily 5 group A member 1)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Nr5a1 (nuclear receptor subfamily 5, group A, member 1)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Nr5a1 (nuclear receptor subfamily 5 group A member 1)
Pan paniscus (bonobo/pygmy chimpanzee) : NR5A1 (nuclear receptor subfamily 5 group A member 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Nr5a1 (nuclear receptor subfamily 5 group A member 1)
Sus scrofa (pig) : NR5A1 (nuclear receptor subfamily 5 group A member 1)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm38238,692,656 - 38,714,542 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv37238,548,180 - 38,570,062 (-)NCBIGRCm37mm9NCBIm37
MGSCv36238,514,636 - 38,536,512 (-)NCBImm8
Celera240,416,849 - 40,438,726 (-)NCBICelera
Cytogenetic Map2 BNCBI
cM Map224.42NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Nr5a1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 68494
Created: 2001-07-11
Species: Mus musculus
Last Modified: 2019-10-16
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.