Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   
Gene: Nr5a1 (nuclear receptor subfamily 5, group A, member 1) Mus musculus
Analyze
Symbol: Nr5a1
Name: nuclear receptor subfamily 5, group A, member 1
RGD ID: 68494
Description: Exhibits RNA polymerase II cis-regulatory region sequence-specific DNA binding activity and chromatin binding activity. Involved in several processes, including adrenal gland development; gonad development; and regulation of gonad development. Localizes to RNA polymerase II transcription regulator complex and nucleus. Is expressed in several structures, including central nervous system; endocrine gland; genitourinary system; hemolymphoid system; and respiratory system. Used to study hypogonadotropic hypogonadism. Human ortholog(s) of this gene implicated in 46,XX sex reversal 4; 46,XY sex reversal 3; Zellweger syndrome; premature ovarian failure; and spermatogenic failure 8. Orthologous to human NR5A1 (nuclear receptor subfamily 5 group A member 1); INTERACTS WITH 1,2-dimethylhydrazine; 17alpha-ethynylestradiol; 17beta-estradiol.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: Ad4; Ad4BP; adrenal 4-binding protein; E; ELP; ELP-3; embryonal long terminal repeat-binding protein; embryonal LTR-binding protein; Ftz-F1; Ftzf1; fushi tarazu 1 factor homolog; fushi tarazu factor homolog 1; MGC124277; MGC124278; nuclear receptor subfamily 5 group A member 1; SF; SF-; SF-1; SF1; steroid hormone receptor Ad4BP; steroid hydroxylase positive regulator; steroidogenic factor 1; STF-1
Orthologs:
Homo sapiens (human) : NR5A1 (nuclear receptor subfamily 5 group A member 1)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Nr5a1 (nuclear receptor subfamily 5, group A, member 1)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Nr5a1 (nuclear receptor subfamily 5 group A member 1)
Pan paniscus (bonobo/pygmy chimpanzee) : NR5A1 (nuclear receptor subfamily 5 group A member 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Nr5a1 (nuclear receptor subfamily 5 group A member 1)
Sus scrofa (pig) : NR5A1 (nuclear receptor subfamily 5 group A member 1)
Chlorocebus sabaeus (African green monkey) : NR5A1 (nuclear receptor subfamily 5 group A member 1)
Heterocephalus glaber (naked mole-rat) : Nr5a1 (nuclear receptor subfamily 5 group A member 1)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39238,582,668 - 38,604,554 (-)NCBI
GRCm38238,692,656 - 38,714,542 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl238,692,656 - 38,714,542 (-)EnsemblGRCm38mm10GRCm38
MGSCv37238,548,180 - 38,570,062 (-)NCBIGRCm37mm9NCBIm37
MGSCv36238,514,636 - 38,536,512 (-)NCBImm8
Celera240,416,849 - 40,438,726 (-)NCBICelera
Cytogenetic Map2BNCBI
cM Map224.42NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Nr5a1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 68494
Created: 2001-07-11
Species: Mus musculus
Last Modified: 2020-10-13
Status: ACTIVE



NHLBI Logo

RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.