Nr5a1 (nuclear receptor subfamily 5, group A, member 1) - Rat Genome Database

Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Gene: Nr5a1 (nuclear receptor subfamily 5, group A, member 1) Mus musculus
Analyze
Symbol: Nr5a1
Name: nuclear receptor subfamily 5, group A, member 1
RGD ID: 68494
MGI Page MGI
Description: Enables RNA polymerase II cis-regulatory region sequence-specific DNA binding activity and chromatin binding activity. Involved in negative regulation of female gonad development and positive regulation of male gonad development. Acts upstream of or within several processes, including adrenal gland development; gonad development; and maintenance of protein location in nucleus. Located in nucleus. Part of RNA polymerase II transcription regulator complex. Is expressed in several structures, including central nervous system; endocrine gland; genitourinary system; hemolymphoid system; and respiratory system. Used to study hypogonadotropic hypogonadism. Human ortholog(s) of this gene implicated in 46,XX sex reversal 4; 46,XY sex reversal 3; Zellweger syndrome; primary ovarian insufficiency 7; and spermatogenic failure 8. Orthologous to human NR5A1 (nuclear receptor subfamily 5 group A member 1); INTERACTS WITH 1,2-dimethylhydrazine; 17alpha-ethynylestradiol; 17beta-estradiol.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: Ad4; Ad4BP; adrenal 4-binding protein; E; ELP; ELP-3; embryonal long terminal repeat-binding protein; embryonal LTR-binding protein; Ftz-F1; Ftzf1; fushi tarazu 1 factor homolog; fushi tarazu factor homolog 1; MGC124277; MGC124278; nuclear receptor subfamily 5 group A member 1; SF; SF-; SF-1; SF1; steroid hormone receptor Ad4BP; steroid hydroxylase positive regulator; steroidogenic factor 1; STF-1
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39238,582,668 - 38,604,554 (-)NCBIGRCm39mm39
GRCm39 Ensembl238,582,668 - 38,604,554 (-)Ensembl
GRCm38238,692,656 - 38,714,542 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl238,692,656 - 38,714,542 (-)EnsemblGRCm38mm10GRCm38
MGSCv37238,548,180 - 38,570,062 (-)NCBIGRCm37mm9NCBIm37
MGSCv36238,514,636 - 38,536,512 (-)NCBImm8
Celera240,416,849 - 40,438,726 (-)NCBICelera
Cytogenetic Map2BNCBI
cM Map224.42NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(25R)-cholest-5-ene-3beta,26-diol  (ISO)
(S)-nicotine  (ISO)
1,1,1-trichloro-2,2-bis(4-hydroxyphenyl)ethane  (ISO)
1,2-dimethylhydrazine  (EXP)
17alpha-ethynylestradiol  (EXP)
17beta-estradiol  (EXP,ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
20-hydroxycholesterol  (EXP)
22-Hydroxycholesterol  (ISO)
25-hydroxycholesterol  (ISO)
26-hydroxycholesterol  (ISO)
5-aza-2'-deoxycytidine  (ISO)
6-propyl-2-thiouracil  (EXP,ISO)
8-Br-cAMP  (EXP)
aflatoxin B1  (ISO)
all-trans-retinoic acid  (EXP)
allethrin  (ISO)
ammonium chloride  (ISO)
antimycin A  (ISO)
aristolochic acid  (ISO)
atrazine  (EXP,ISO)
azoxystrobin  (ISO)
bafilomycin A1  (ISO)
benzo[a]pyrene  (EXP,ISO)
benzo[e]pyrene  (ISO)
bis(2-ethylhexyl) phthalate  (EXP,ISO)
bisphenol A  (EXP,ISO)
Bisphenol B  (ISO)
bucladesine  (EXP,ISO)
Butylparaben  (ISO)
cadmium atom  (ISO)
cadmium dichloride  (EXP,ISO)
caffeine  (ISO)
chlorpyrifos  (ISO)
chromium(6+)  (ISO)
colforsin daropate hydrochloride  (ISO)
crocidolite asbestos  (EXP)
cyhalothrin  (ISO)
cypermethrin  (ISO)
daidzein  (ISO)
daidzein 7-O-beta-D-glucoside  (ISO)
decabromodiphenyl ether  (EXP,ISO)
deguelin  (ISO)
deoxynivalenol  (ISO)
diazinon  (ISO)
dibutyl phthalate  (ISO)
dibutylstannane  (ISO)
diethyl phthalate  (ISO)
diethylstilbestrol  (EXP)
endosulfan  (ISO)
ethanol  (EXP,ISO)
fenitrothion  (ISO)
fenpyroximate  (ISO)
fenvalerate  (ISO)
genistein  (EXP,ISO)
genistein 7-O-beta-D-glucoside  (ISO)
glycitein  (ISO)
glycitin  (ISO)
icariin  (EXP)
imidacloprid  (ISO)
iprodione  (ISO)
L-ascorbic acid  (ISO)
methapyrilene  (ISO)
mono(2-ethylhexyl) phthalate  (EXP)
nicotine  (ISO)
phorbol 13-acetate 12-myristate  (EXP)
picoxystrobin  (ISO)
proanthocyanidin  (ISO)
progesterone  (EXP,ISO)
prostaglandin E2  (ISO)
pyruvic acid  (ISO)
quercetin  (ISO)
rotenone  (ISO)
simazine  (ISO)
sirolimus  (ISO)
T-2 toxin  (ISO)
tamoxifen  (ISO)
tebufenpyrad  (ISO)
testosterone  (EXP,ISO)
testosterone enanthate  (ISO)
Tetrachlorobisphenol A  (ISO)
trichostatin A  (ISO)
trimethyltin  (ISO)
triphenylstannane  (ISO)
valproic acid  (ISO)
vinclozolin  (ISO)
wortmannin  (ISO)
zearalenone  (ISO)
zinc oxide  (ISO)
ziram  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype
abnormal adrenal gland zona glomerulosa morphology  (IAGP)
abnormal aldosterone level  (IAGP)
abnormal corticosterone level  (IAGP)
abnormal female reproductive system morphology  (IAGP)
abnormal gonadal ridge morphology  (IAGP)
abnormal hypothalamus morphology  (IAGP)
abnormal innervation  (IAGP)
abnormal Leydig cell morphology  (IAGP)
abnormal male reproductive system morphology  (IAGP)
abnormal neuron differentiation  (IAGP)
abnormal ovulation  (IAGP)
abnormal pituitary gland morphology  (IAGP)
abnormal primary sex determination  (IAGP)
abnormal progesterone level  (IAGP)
abnormal reproductive system morphology  (IAGP)
abnormal secondary sex determination  (IAGP)
abnormal seminiferous tubule morphology  (IAGP)
abnormal sex gland morphology  (IAGP)
abnormal sexual interaction  (IAGP)
abnormal spermatid morphology  (IAGP)
abnormal spermatogenesis  (IAGP)
abnormal testis cord formation  (IAGP)
abnormal testis development  (IAGP)
abnormal testis morphology  (IAGP)
abnormal testosterone level  (IAGP)
abnormal ventromedial hypothalamic nucleus morphology  (IAGP)
absent adrenal gland  (IAGP)
absent corpus luteum  (IAGP)
absent mature ovarian follicles  (IAGP)
absent ovary  (IAGP)
absent sexual maturation  (IAGP)
absent testes  (IAGP)
agonadal  (IAGP)
anovulation  (IAGP)
arrest of spermatogenesis  (IAGP)
cryptorchism  (IAGP)
decreased body weight  (IAGP)
decreased circulating follicle stimulating hormone level  (IAGP)
decreased circulating luteinizing hormone level  (IAGP)
decreased circulating testosterone level  (IAGP)
decreased follicle stimulating hormone level  (IAGP)
decreased gonadotroph cell number  (IAGP)
decreased Leydig cell number  (IAGP)
decreased luteinizing hormone level  (IAGP)
decreased male germ cell number  (IAGP)
decreased mature ovarian follicle number  (IAGP)
decreased ovary weight  (IAGP)
decreased testis weight  (IAGP)
decreased ventromedial hypothalamic nucleus size  (IAGP)
delayed vaginal opening  (IAGP)
external male genitalia hypoplasia  (IAGP)
female infertility  (IAGP)
impaired ovarian folliculogenesis  (IAGP)
increased Leydig cell number  (IAGP)
infertility  (IAGP)
internal male genitalia hypoplasia  (IAGP)
male infertility  (IAGP)
no abnormal phenotype detected  (IAGP)
oligozoospermia  (IAGP)
ovarian follicular cyst  (IAGP)
ovary hemorrhage  (IAGP)
ovary hypoplasia  (IAGP)
perinatal lethality, complete penetrance  (IAGP)
postnatal lethality, complete penetrance  (IAGP)
postnatal lethality, incomplete penetrance  (IAGP)
premature death  (IAGP)
prostate gland hypoplasia  (IAGP)
retention of the adrenal gland x-zone  (IAGP)
secondary sex reversal  (IAGP)
seminal vesicle hypoplasia  (IAGP)
seminiferous tubule degeneration  (IAGP)
small adrenal glands  (IAGP)
small gonad  (IAGP)
small ovary  (IAGP)
small testis  (IAGP)
testis hypoplasia  (IAGP)
uterus hypoplasia  (IAGP)
References

Additional References at PubMed
PMID:1406703   PMID:1545809   PMID:7476982   PMID:7479914   PMID:7490110   PMID:7491115   PMID:7588219   PMID:7588417   PMID:7659091   PMID:7789992   PMID:7958897   PMID:8058073  
PMID:8187173   PMID:8205615   PMID:8395013   PMID:8413309   PMID:8543574   PMID:8544843   PMID:8563022   PMID:8668203   PMID:8806624   PMID:8938589   PMID:9013759   PMID:9121493  
PMID:9291464   PMID:9482669   PMID:9751506   PMID:9843195   PMID:9843206   PMID:9879712   PMID:9922094   PMID:10029587   PMID:10219237   PMID:10230405   PMID:10319323   PMID:10319325  
PMID:10349636   PMID:10367888   PMID:10407134   PMID:10418976   PMID:10446902   PMID:10478838   PMID:10588713   PMID:10588871   PMID:10650968   PMID:10654601   PMID:10675033   PMID:10706291  
PMID:10848616   PMID:10880989   PMID:10922068   PMID:10949085   PMID:10963870   PMID:11042159   PMID:11071856   PMID:11076861   PMID:11121051   PMID:11124111   PMID:11217851   PMID:11287187  
PMID:11416865   PMID:11420128   PMID:11420609   PMID:11574675   PMID:11602358   PMID:11738790   PMID:11738791   PMID:11796516   PMID:11796523   PMID:11807026   PMID:11830575   PMID:11861512  
PMID:11875113   PMID:11923472   PMID:11923473   PMID:11932209   PMID:12050120   PMID:12130543   PMID:12183375   PMID:12223418   PMID:12239114   PMID:12242296   PMID:12351700   PMID:12360237  
PMID:12456803   PMID:12466851   PMID:12477932   PMID:12482977   PMID:12530656   PMID:12530657   PMID:12538527   PMID:12610109   PMID:12651892   PMID:12697720   PMID:12719432   PMID:12727442  
PMID:12730328   PMID:12732619   PMID:12732652   PMID:12835383   PMID:12851310   PMID:12861022   PMID:12917325   PMID:12920232   PMID:12920234   PMID:12949260   PMID:12972182   PMID:14595835  
PMID:14645112   PMID:14678822   PMID:14681479   PMID:14726490   PMID:15003627   PMID:15026179   PMID:15056615   PMID:15118069   PMID:15192080   PMID:15192092   PMID:15211353   PMID:15229180  
PMID:15289436   PMID:15307147   PMID:15533830   PMID:15579738   PMID:15581876   PMID:15590666   PMID:15618518   PMID:15666831   PMID:15666836   PMID:15707893   PMID:15713642   PMID:15721253  
PMID:15733675   PMID:15737622   PMID:15746887   PMID:15761027   PMID:15767781   PMID:15769848   PMID:15829514   PMID:15836771   PMID:15843621   PMID:15899914   PMID:15937924   PMID:15939083  
PMID:15944188   PMID:15944199   PMID:15961510   PMID:15970507   PMID:15994202   PMID:16003771   PMID:16109736   PMID:16141072   PMID:16141073   PMID:16176945   PMID:16183868   PMID:16207837  
PMID:16339206   PMID:16339274   PMID:16353668   PMID:16384867   PMID:16425238   PMID:16452715   PMID:16458255   PMID:16466956   PMID:16469766   PMID:16702404   PMID:16705164   PMID:16877546  
PMID:16920405   PMID:16943277   PMID:16971476   PMID:16973757   PMID:17017126   PMID:17053042   PMID:17082260   PMID:17086185   PMID:17095585   PMID:17218410   PMID:17392792   PMID:17420277  
PMID:17495005   PMID:17537799   PMID:17709382   PMID:17761949   PMID:17767488   PMID:17919533   PMID:18037398   PMID:18077674   PMID:18287559   PMID:18288644   PMID:18325326   PMID:18351662  
PMID:18372344   PMID:18388192   PMID:18391526   PMID:18391535   PMID:18403409   PMID:18417734   PMID:18418875   PMID:18436715   PMID:18454134   PMID:18511494   PMID:18566117   PMID:18599507  
PMID:18669597   PMID:18697938   PMID:18703422   PMID:18775421   PMID:18809574   PMID:18838537   PMID:18927153   PMID:18927154   PMID:18987158   PMID:18988706   PMID:19015234   PMID:19100252  
PMID:19124014   PMID:19139274   PMID:19147497   PMID:19188450   PMID:19268447   PMID:19269320   PMID:19301398   PMID:19389484   PMID:19457926   PMID:19549635   PMID:19628584   PMID:19696014  
PMID:19737523   PMID:19753101   PMID:19757380   PMID:19842175   PMID:19884258   PMID:19955443   PMID:19995909   PMID:20026603   PMID:20059953   PMID:20118198   PMID:20144603   PMID:20211142  
PMID:20339005   PMID:20375256   PMID:20394914   PMID:20436479   PMID:20540774   PMID:20650879   PMID:20805495   PMID:20823062   PMID:20932939   PMID:20943815   PMID:20962046   PMID:20962249  
PMID:20969841   PMID:21074524   PMID:21108604   PMID:21111771   PMID:21129436   PMID:21169726   PMID:21255566   PMID:21256921   PMID:21262217   PMID:21267068   PMID:21343250   PMID:21566663  
PMID:21586554   PMID:21610156   PMID:21636788   PMID:21678401   PMID:21731673   PMID:21757499   PMID:21820362   PMID:21828248   PMID:21873635   PMID:21900680   PMID:21906594   PMID:22128023  
PMID:22128028   PMID:22186409   PMID:22294746   PMID:22419830   PMID:22496664   PMID:22529212   PMID:22593182   PMID:22653058   PMID:22723422   PMID:22945632   PMID:22987798   PMID:23070814  
PMID:23087174   PMID:23091613   PMID:23095882   PMID:23102580   PMID:23102581   PMID:23125070   PMID:23136395   PMID:23166296   PMID:23219870   PMID:23274689   PMID:23283339   PMID:23300469  
PMID:23300479   PMID:23376610   PMID:23471215   PMID:23518926   PMID:23568777   PMID:23637637   PMID:23685333   PMID:23754801   PMID:23769843   PMID:23840809   PMID:23874227   PMID:23889939  
PMID:23961995   PMID:23987514   PMID:24009392   PMID:24035414   PMID:24130552   PMID:24131628   PMID:24135228   PMID:24189494   PMID:24227653   PMID:24232453   PMID:24451388   PMID:24673559  
PMID:24712878   PMID:24828505   PMID:24899573   PMID:24952961   PMID:25111584   PMID:25224227   PMID:25421435   PMID:25463758   PMID:25505333   PMID:25543145   PMID:25575455   PMID:25591470  
PMID:25661788   PMID:25668066   PMID:25855264   PMID:25864637   PMID:25917826   PMID:25933105   PMID:25960166   PMID:26067405   PMID:26194606   PMID:26269506   PMID:26296153   PMID:26697723  
PMID:27209204   PMID:27214556   PMID:27226320   PMID:27313319   PMID:27445727   PMID:27455990   PMID:27578785   PMID:27598259   PMID:27621062   PMID:27833742   PMID:27862528   PMID:27871073  
PMID:27874828   PMID:27888191   PMID:28118982   PMID:28202838   PMID:28325912   PMID:28360133   PMID:28426816   PMID:28506993   PMID:28684471   PMID:28706241   PMID:28893949   PMID:28911199  
PMID:28949961   PMID:29567944   PMID:29735715   PMID:29796621   PMID:29879378   PMID:29903884   PMID:30040984   PMID:30063881   PMID:30067986   PMID:30085028   PMID:30212841   PMID:30291164  
PMID:30307165   PMID:30375389   PMID:30518625   PMID:30541888   PMID:30776325   PMID:30872705   PMID:30877223   PMID:30912742   PMID:31530896   PMID:31712577   PMID:31913463   PMID:32020708  
PMID:32181567   PMID:32253239   PMID:32301970   PMID:32365547   PMID:32450947   PMID:32453714   PMID:32493750   PMID:32497091   PMID:32792525   PMID:32945847   PMID:33004521   PMID:33108146  
PMID:33397036   PMID:33431871   PMID:33500353   PMID:33600763   PMID:33627800   PMID:33795686   PMID:33864885   PMID:33869166   PMID:33951437   PMID:33964295   PMID:34288113  


Genomics

Comparative Map Data
Nr5a1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39238,582,668 - 38,604,554 (-)NCBIGRCm39mm39
GRCm39 Ensembl238,582,668 - 38,604,554 (-)Ensembl
GRCm38238,692,656 - 38,714,542 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl238,692,656 - 38,714,542 (-)EnsemblGRCm38mm10GRCm38
MGSCv37238,548,180 - 38,570,062 (-)NCBIGRCm37mm9NCBIm37
MGSCv36238,514,636 - 38,536,512 (-)NCBImm8
Celera240,416,849 - 40,438,726 (-)NCBICelera
Cytogenetic Map2BNCBI
cM Map224.42NCBI
NR5A1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl9124,481,236 - 124,507,420 (-)EnsemblGRCh38hg38GRCh38
GRCh389124,481,236 - 124,507,399 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh379127,243,515 - 127,269,678 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 369126,283,336 - 126,309,520 (-)NCBINCBI36hg18NCBI36
Build 349124,323,069 - 124,349,253NCBI
Celera997,890,732 - 97,916,915 (-)NCBI
Cytogenetic Map9q33.3NCBI
HuRef996,856,059 - 96,882,213 (-)NCBIHuRef
CHM1_19127,392,508 - 127,418,653 (-)NCBICHM1_1
Nr5a1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2322,464,786 - 22,486,328 (-)NCBImRatBN7.2
mRatBN7.2 Ensembl322,465,502 - 22,486,328 (-)Ensembl
Rnor_6.0322,998,900 - 23,020,441 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl322,999,616 - 23,020,441 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0328,223,427 - 28,244,968 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4318,498,913 - 18,519,738 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1318,395,933 - 18,412,441 (-)NCBI
Celera320,898,726 - 20,919,551 (-)NCBICelera
Cytogenetic Map3q12NCBI
Nr5a1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554193,632,220 - 3,654,375 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554193,632,248 - 3,654,367 (+)NCBIChiLan1.0ChiLan1.0
NR5A1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.19124,122,968 - 124,149,292 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl9124,122,968 - 124,149,292 (-)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v0995,605,282 - 95,628,773 (-)NCBIMhudiblu_PPA_v0panPan3
Nr5a1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024404947192,970,909 - 193,007,215 (-)NCBI
SpeTri2.0NW_00493648712,739,445 - 12,763,729 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
NR5A1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1265,284,493 - 265,311,417 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11265,284,491 - 265,311,547 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21299,123,683 - 299,135,326 (+)NCBISscrofa10.2Sscrofa10.2susScr3
Pig Cytomap1q210-q211NCBI
NR5A1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11213,640,453 - 13,666,748 (+)NCBIChlSab1.1chlSab2
ChlSab1.1 Ensembl1213,640,473 - 13,666,863 (+)EnsemblChlSab1.1chlSab2
Vero_WHO_p1.0NW_0236660792,411,630 - 2,438,042 (-)NCBIVero_WHO_p1.0
Nr5a1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462476010,603,504 - 10,626,259 (+)NCBIHetGla_female_1.0hetGla2

Position Markers
Nr5a1  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38238,693,944 - 38,694,061UniSTSGRCm38
MGSCv37238,549,464 - 38,549,581UniSTSGRCm37
Celera240,418,133 - 40,418,250UniSTS
Cytogenetic Map2BUniSTS
cM Map223.5UniSTS
cM Map223.5UniSTS
D10584  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38238,701,347 - 38,701,462UniSTSGRCm38
MGSCv37238,556,867 - 38,556,982UniSTSGRCm37
Celera240,425,536 - 40,425,651UniSTS
Cytogenetic Map2BUniSTS
cM Map223.5UniSTS
Whitehead/MRC_RH2604.26UniSTS
Sf1  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map2BUniSTS
cM Map19 UniSTS
cM Map223.5UniSTS
PMC140651P1  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38238,708,093 - 38,708,213UniSTSGRCm38
MGSCv37238,563,613 - 38,563,733UniSTSGRCm37
Celera240,432,282 - 40,432,402UniSTS
Cytogenetic Map2BUniSTS
cM Map223.5UniSTS
Nr5a1  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38238,693,593 - 38,693,905UniSTSGRCm38
MGSCv37238,549,113 - 38,549,425UniSTSGRCm37
Celera240,417,782 - 40,418,094UniSTS
Cytogenetic Map2BUniSTS
cM Map223.5UniSTS
Nr5a1  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map2BUniSTS
Nr5a1  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map2BUniSTS
Nr5a1  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map2BUniSTS
Nr5a1  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map2BUniSTS
D10584  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38238,701,649 - 38,701,764UniSTSGRCm38
MGSCv37238,557,169 - 38,557,284UniSTSGRCm37
Celera240,425,838 - 40,425,953UniSTS
Cytogenetic Map2BUniSTS
Whitehead/MRC_RH2616.21UniSTS


QTLs in Region (GRCm38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1301769Orgwq2_morgan weight QTL 2 (mouse)Not determined2388608993591306Mouse
1301980Fcsa5_mfemoral cross-sectional area 5 (mouse)Not determined2778910341789249Mouse
1301790Pcfm1_mperiosteal circumference and femur length 1 (mouse)Not determined2834628442346384Mouse
10043876Adip22_madiposity 22 (mouse)Not determined2841803942418228Mouse
1300624Insq7_minsulin QTL 7 (mouse)Not determined2949443443494563Mouse
10755513Amzn4_manatomical modifier of Zfp423 4 (mouse)2949443443494563Mouse
8552707Cia23_mcollagen induced arthritis QTL 23 (mouse)Not determined21212472666726109Mouse
1301641Sbmd2_mspinal bone mineral density 2 (mouse)Not determined21432455548324701Mouse
1357454Kidq1_mkidney weight QTL 1 (mouse)Not determined220892967119064359Mouse
1357436Splq1_mspleen weight QTL 1 (mouse)Not determined220892967119064359Mouse
1357829Lvrq1_mliver weight QTL 1 (mouse)Not determined220892967119064359Mouse
1558899Egq1_mearly growth QTL 1 (mouse)Not determined220892967119064359Mouse
1558738W6q1_mweight 6 weeks QTL 1 (mouse)Not determined220892967119064359Mouse
1558966W10q9_mweight 10 weeks QTL 9 (mouse)Not determined220892967119064359Mouse
1558915W3q1_mweight 3 weeks QTL 1 (mouse)Not determined220892967119064359Mouse
1357681Hrtq1_mheart weight QTL 1 (mouse)Not determined220892967119064359Mouse
1357881Estoq1_membryo survival total QTL 1 (mouse)Not determined220892967119064359Mouse
39128209Lwq14_mliver weight QTL 14 (mouse)220892967119064359Mouse
4141708Pbwg1.2_mpostnatal body weight growth 1.2 (mouse)Not determined2123971355239859Mouse
1301376Etohc1_methanol consumption 1 (mouse)Not determined22123971355239859Mouse
13463470Tubisq1_mtubulointerstitial injury severity, QTL 1 (mouse)22379913357799257Mouse
1302174Dssc2_mdextran sodium sulfate induced colitis QTL2 (mouse)Not determined224334620148858457Mouse
26884438Sklq12_mskull length QTL 12, 16 week (mouse)22470000055000000Mouse
4142130Pgis2_mproteoglycan induced spondylitis 2 (mouse)Not determined22541803957081799Mouse
12904005Cfq2_mconditioned fear QTL 2 (mouse)22713263056506216Mouse
1300577Capsq1_mcapsaicin sensitivity related QTL 1 (mouse)Not determined22771204884183040Mouse
14746979Manh51_mmandible shape 51 (mouse)22907111763071117Mouse
14746997Mancz2_mmandible centroid size 2 (mouse)22907111763071117Mouse
4141854T2dm2sa_mtype 2 diabetes mellitus 2 in SMXA RI mice (mouse)Not determined229417935148533014Mouse
12904008Cfq6_mconditioned fear QTL 6 (mouse)23131302344618192Mouse
4141236Hbnr5_mHeligmosomoides bakeri nematode resistance 5 (mouse)Not determined31324555105313225Mouse
4142447Pbwg1.7_mpostnatal body weight growth 1.7 (mouse)Not determined3590731269907394Mouse
4141186Pbwg1.8_mpostnatal body weight growth 1.8 (mouse)Not determined3590731269907394Mouse
4142133Pbwg1.6_mpostnatal body weight growth 1.6 (mouse)Not determined3590731269907394Mouse
1559001Eae33_mexperimental allergic encephalomyelitis susceptibility 33 (mouse)Not determined23610166771779068Mouse
10449145Lanq1_mlanosterol level QTL 1 (mouse)23823971367242263Mouse
10449150Pvldlc1_mplasma VLDL-cholesterol 1 (mouse)23823971367242263Mouse
10449151Hdl8_mhigh density lipoprotein (HDL) level 8 (mouse)23823971367242263Mouse

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:1552
Count of miRNA genes:474
Interacting mature miRNAs:606
Transcripts:ENSMUST00000028084, ENSMUST00000112883, ENSMUST00000149690
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSMUST00000028084   ⟹   ENSMUSP00000028084
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl238,582,672 - 38,604,554 (-)Ensembl
GRCm38.p6 Ensembl238,692,660 - 38,714,542 (-)Ensembl
RefSeq Acc Id: ENSMUST00000112883   ⟹   ENSMUSP00000108504
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl238,582,668 - 38,602,246 (-)Ensembl
GRCm38.p6 Ensembl238,692,656 - 38,712,234 (-)Ensembl
RefSeq Acc Id: ENSMUST00000149690
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl238,591,334 - 38,601,200 (-)Ensembl
GRCm38.p6 Ensembl238,701,322 - 38,711,188 (-)Ensembl
RefSeq Acc Id: NM_001316687   ⟹   NP_001303616
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39238,582,668 - 38,602,246 (-)NCBI
GRCm38238,692,656 - 38,712,234 (-)NCBI
Sequence:
RefSeq Acc Id: NM_139051   ⟹   NP_620639
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39238,582,672 - 38,604,554 (-)NCBI
GRCm38238,692,660 - 38,714,542 (-)NCBI
MGSCv37238,548,180 - 38,570,062 (-)RGD
Celera240,416,849 - 40,438,726 (-)RGD
cM Map2 ENTREZGENE
Sequence:
Reference Sequences
RefSeq Acc Id: NP_620639   ⟸   NM_139051
- UniProtKB: P33242 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: NP_001303616   ⟸   NM_001316687
- UniProtKB: P33242 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: ENSMUSP00000028084   ⟸   ENSMUST00000028084
RefSeq Acc Id: ENSMUSP00000108504   ⟸   ENSMUST00000112883
Protein Domains
NR LBD   Nuclear receptor

Promoters
RGD ID:6831949
Promoter ID:MM_KWN:29022
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:Brain,   Kidney,   Lung
Transcripts:OTTMUST00000030855
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv36238,566,121 - 38,566,621 (-)MPROMDB
RGD ID:6832500
Promoter ID:MM_KWN:29023
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:Kidney
Transcripts:ENSMUST00000112883,   OTTMUST00000030837
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv36238,566,556 - 38,567,056 (+)MPROMDB
RGD ID:6877210
Promoter ID:EPDNEW_M2056
Type:multiple initiation site
Name:Nr5a1_1
Description:Mus musculus nuclear receptor subfamily 5, group A, member 1, transcript variant 2, mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38238,714,502 - 38,714,562EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:1346833 AgrOrtholog
Ensembl Genes ENSMUSG00000026751 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Protein ENSMUSP00000028084 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSMUSP00000108504 ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSMUST00000028084 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSMUST00000112883 ENTREZGENE, UniProtKB/Swiss-Prot
Gene3D-CATH 1.10.565.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  3.30.50.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro NHR-like_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  NR5_fam UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Nucl_hrmn_rcpt_lig-bd UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Nuclear_hrmn_rcpt UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Znf_hrmn_rcpt UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Znf_NHR/GATA UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:26423 UniProtKB/Swiss-Prot
MGD MGI:1346833 ENTREZGENE
NCBI Gene 26423 ENTREZGENE
PANTHER PTHR24086 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam Hormone_recep UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  zf-C4 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Nr5a1 PhenoGen
PIRSF Nuc_orph_FTZ-F1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PRINTS STRDHORMONER UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  STROIDFINGER UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE NR_LBD UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  NUCLEAR_REC_DBD_1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  NUCLEAR_REC_DBD_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART HOLI UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ZnF_C4 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF48508 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt P33242 ENTREZGENE
  P97782_MOUSE UniProtKB/TrEMBL
  Q3U0G1_MOUSE UniProtKB/TrEMBL
  STF1_MOUSE UniProtKB/Swiss-Prot
UniProt Secondary Q812G5 UniProtKB/Swiss-Prot