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Gene: Nr5a1 (nuclear receptor subfamily 5, group A, member 1) Mus musculus
Symbol: Nr5a1
Name: nuclear receptor subfamily 5, group A, member 1
Description: Exhibits RNA polymerase II distal enhancer sequence-specific DNA binding activity and chromatin binding activity. Involved in several processes, including adrenal gland development; gonad development; and regulation of gonad development. Localizes to the RNA polymerase II transcription factor complex. Used to study hypogonadotropic hypogonadism. Human ortholog(s) of this gene implicated in 46 XY gonadal dysgenesis; Zellweger syndrome; premature ovarian failure; and spermatogenic failure 8. Is expressed in several structures, including central nervous system; endocrine gland; genitourinary system; hemolymphoid system; and respiratory system. Orthologous to human NR5A1 (nuclear receptor subfamily 5 group A member 1); INTERACTS WITH 17alpha-ethynylestradiol; 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: Ad4BP; adrenal 4-binding protein; ELP; ELP-3; embryonal long terminal repeat-binding protein; embryonal LTR-binding protein; Ftz-F1; Ftzf1; fushi tarazu 1 factor homolog; fushi tarazu factor homolog 1; MGC124277; MGC124278; nuclear receptor subfamily 5 group A member 1; SF-1; SF1; steroid hormone receptor Ad4BP; steroid hydroxylase positive regulator; steroidogenic factor 1; STF-1
Homo sapiens (human) : NR5A1 (nuclear receptor subfamily 5 group A member 1)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Nr5a1 (nuclear receptor subfamily 5, group A, member 1)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Nr5a1 (nuclear receptor subfamily 5 group A member 1)
Pan paniscus (bonobo/pygmy chimpanzee) : NR5A1 (nuclear receptor subfamily 5 group A member 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Nr5a1 (nuclear receptor subfamily 5 group A member 1)
Sus scrofa (pig) : NR5A1 (nuclear receptor subfamily 5 group A member 1)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm38238,692,656 - 38,714,542 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv37238,548,180 - 38,570,062 (-)NCBIGRCm37mm9NCBIm37
MGSCv36238,514,636 - 38,536,512 (-)NCBImm8
Celera240,416,849 - 40,438,726 (-)NCBICelera
Cytogenetic Map2 BNCBI
cM Map224.42NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status


Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Nr5a1
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 68494
Created: 2001-07-11
Species: Mus musculus
Last Modified: 2019-10-16
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.