ACAA1 (acetyl-CoA acyltransferase 1) - Rat Genome Database

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Gene: ACAA1 (acetyl-CoA acyltransferase 1) Pan paniscus
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Symbol: ACAA1
Name: acetyl-CoA acyltransferase 1
RGD ID: 11859757
Description: ENCODES a protein that exhibits acetate CoA-transferase activity (ortholog); acetyl-CoA C-acyltransferase activity (ortholog); acetyl-CoA C-myristoyltransferase activity (ortholog); INVOLVED IN alpha-linolenic acid metabolic process (ortholog); bile acid metabolic process (ortholog); fatty acid beta-oxidation (ortholog); ASSOCIATED WITH Brugada syndrome (ortholog); congestive heart failure (ortholog); Experimental Diabetes Mellitus (ortholog); FOUND IN peroxisomal matrix (ortholog); peroxisome (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: 3-ketoacyl-CoA thiolase, peroxisomal
RGD Orthologs
Human
Mouse
Rat
Dog
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly
Position:
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2238,075,928 - 38,090,823 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1338,080,692 - 38,095,705 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0338,020,439 - 38,035,341 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1338,302,976 - 38,317,009 (-)NCBIpanpan1.1PanPan1.1panPan2
JBrowse: View Region in Genome Browser (JBrowse)
Model



  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
ACAA1BonoboExperimental Diabetes Mellitus  ISOAcaa1a (Rattus norvegicus)9068941mRNA:increased expression:heartRGDPMID:17632588 and REF_RGD_ID:2313044
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
ACAA1BonoboBrugada syndrome  ISOACAA1 (Homo sapiens)8554872ClinVar Annotator: match by term: Brugada syndromeClinVarPMID:20129283 more ...
ACAA1Bonobovisceral heterotaxy 4  ISOACAA1 (Homo sapiens)8554872ClinVar Annotator: match by term: Heterotaxy more ...ClinVarPMID:28492532
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
ACAA1Bonobocongestive heart failure  ISOAcaa1b (Mus musculus)9068941CTD Direct Evidence: marker/mechanismCTDPMID:26670611


Biological Process
1 to 14 of 14 rows

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
ACAA1Bonoboalpha-linolenic acid metabolic process involved_inISOMGI:21484919068941 PMID:15043762MGIPMID:15043762
ACAA1Bonobobile acid metabolic process involved_inISOACAA1 (Homo sapiens)9068941 PMID:2318981UniProtPMID:2318981
ACAA1Bonobobile acid metabolic process involved_inISOAcaa1a (Rattus norvegicus)9068941PMID:9325339UniProtPMID:9325339 and REF_RGD_ID:21201257
ACAA1Bonobofatty acid beta-oxidation involved_inISOACAA1 (Homo sapiens)9068941 PMID:2365812 and PMID:2882519UniProtPMID:2365812 and PMID:2882519
ACAA1Bonobofatty acid beta-oxidation involved_inISOUniProtKB:P091109068941PMID:2882519UniProtPMID:2882519 and REF_RGD_ID:8554082
ACAA1Bonobofatty acid beta-oxidation involved_inISOAcaa1a (Rattus norvegicus)9068941PMID:9325339UniProtPMID:9325339 and REF_RGD_ID:21201257
ACAA1Bonobofatty acid beta-oxidation using acyl-CoA oxidase involved_inISOMGI:36173599068941 PMID:15589695MGIPMID:15589695
ACAA1Bonobofatty acid derivative biosynthetic process involved_inISOMGI:21484919068941 PMID:15043762MGIPMID:15043762
ACAA1Bonobolong-chain fatty acid biosynthetic process involved_inISOMGI:21484919068941 PMID:15043762MGIPMID:15043762
ACAA1Bonoboresponse to nutrient  ISOAcaa1a (Rattus norvegicus)9068941 RGDPMID:8954134 and REF_RGD_ID:1598676
ACAA1Bonoboresponse to steroid hormone  ISOAcaa1a (Rattus norvegicus)9068941 RGDPMID:9101583 and REF_RGD_ID:1598675
ACAA1Bonoboresponse to xenobiotic stimulus  ISOAcaa1a (Rattus norvegicus)9068941 RGDPMID:2307679 and REF_RGD_ID:1299138
ACAA1Bonobounsaturated fatty acid biosynthetic process involved_inISOMGI:21484919068941 PMID:15043762MGIPMID:15043762
ACAA1Bonobovery long-chain fatty acid metabolic process involved_inISOACAA1 (Homo sapiens)9068941 PMID:2318981UniProtPMID:2318981
1 to 14 of 14 rows

Cellular Component

  

PMID:30032202  



ACAA1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2238,075,928 - 38,090,823 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1338,080,692 - 38,095,705 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0338,020,439 - 38,035,341 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1338,302,976 - 38,317,009 (-)NCBIpanpan1.1PanPan1.1panPan2
ACAA1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38338,122,715 - 38,137,127 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl338,103,129 - 38,137,242 (-)EnsemblGRCh38hg38GRCh38
GRCh37338,164,206 - 38,178,618 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36338,139,211 - 38,153,619 (-)NCBINCBI36Build 36hg18NCBI36
Build 34338,139,210 - 38,153,619NCBI
Celera338,100,002 - 38,114,534 (-)NCBICelera
Cytogenetic Map3p22.2ENTREZGENE
HuRef338,205,163 - 38,219,695 (-)NCBIHuRef
CHM1_1338,116,181 - 38,130,713 (-)NCBICHM1_1
T2T-CHM13v2.0338,128,384 - 38,142,796 (-)NCBIT2T-CHM13v2.0
Acaa1b
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm399118,977,111 - 118,986,149 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl9118,977,091 - 118,986,161 (-)EnsemblGRCm39 Ensembl
GRCm389119,148,043 - 119,157,093 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl9119,148,023 - 119,157,093 (-)EnsemblGRCm38mm10GRCm38
MGSCv379119,057,161 - 119,066,211 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv369118,996,741 - 119,005,791 (-)NCBIMGSCv36mm8
Celera9119,615,929 - 119,624,979 (-)NCBICelera
Cytogenetic Map9F3NCBI
cM Map971.33NCBI
Acaa1a
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr88127,956,126 - 127,966,348 (+)NCBIGRCr8
mRatBN7.28119,079,401 - 119,088,626 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl8119,079,775 - 119,088,624 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx8124,661,801 - 124,670,662 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.08122,860,818 - 122,869,679 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.08120,694,346 - 120,703,213 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.08128,027,880 - 128,036,471 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl8128,027,958 - 128,036,236 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.08127,234,641 - 127,243,232 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.48124,305,097 - 124,313,887 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.18124,324,833 - 124,333,624 (+)NCBI
Celera8118,231,008 - 118,239,798 (+)NCBICelera
Cytogenetic Map8q32NCBI
ACAA1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1237,889,481 - 7,901,324 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl237,889,500 - 7,901,229 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha237,931,439 - 7,943,297 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0238,179,036 - 8,190,917 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl238,179,041 - 8,190,806 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1237,992,930 - 8,004,823 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0238,134,083 - 8,145,938 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0238,126,342 - 8,138,206 (-)NCBIUU_Cfam_GSD_1.0
ACAA1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1322,964,875 - 23,020,143 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11322,964,844 - 23,020,138 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21325,168,888 - 25,179,542 (-)NCBISscrofa10.2Sscrofa10.2susScr3
ACAA1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1151,282,556 - 1,297,154 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl151,282,650 - 1,297,832 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366606310,012,294 - 10,026,718 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Acaa1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247312,665,228 - 2,676,497 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247312,665,228 - 2,677,248 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

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RefSeq Acc Id: XM_034956131   ⟹   XP_034812022
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2238,075,928 - 38,090,543 (-)NCBI
NHGRI_mPanPan1338,080,692 - 38,095,705 (-)NCBI
Mhudiblu_PPA_v0338,020,439 - 38,035,181 (-)NCBI
RefSeq Acc Id: XM_034956132   ⟹   XP_034812023
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2238,075,928 - 38,090,526 (-)NCBI
NHGRI_mPanPan1338,080,692 - 38,095,440 (-)NCBI
Mhudiblu_PPA_v0338,020,444 - 38,035,186 (-)NCBI
RefSeq Acc Id: XM_034956133   ⟹   XP_034812024
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2238,075,928 - 38,090,823 (-)NCBI
NHGRI_mPanPan1338,080,692 - 38,095,587 (-)NCBI
Mhudiblu_PPA_v0338,020,444 - 38,035,341 (-)NCBI
Protein RefSeqs XP_034812022 (Get FASTA)   NCBI Sequence Viewer  
  XP_034812023 (Get FASTA)   NCBI Sequence Viewer  
  XP_034812024 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: XP_034812022   ⟸   XM_034956131
- Peptide Label: isoform X1
RefSeq Acc Id: XP_034812024   ⟸   XM_034956133
- Peptide Label: isoform X3
RefSeq Acc Id: XP_034812023   ⟸   XM_034956132
- Peptide Label: isoform X2



Database
Acc Id
Source(s)
NCBI Gene ACAA1 ENTREZGENE