CS (citrate synthase) - Rat Genome Database

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Gene: CS (citrate synthase) Pan paniscus
Analyze
Symbol: CS
Name: citrate synthase
RGD ID: 11775295
Description: ENCODES a protein that exhibits citrate (Si)-synthase activity (ortholog); citrate synthase activity (ortholog); INVOLVED IN acetyl-CoA metabolic process (ortholog); citrate metabolic process (ortholog); heart development (ortholog); PARTICIPATES IN citric acid cycle pathway; fumaric aciduria pathway; mitochondrial complex II deficiency pathway; ASSOCIATED WITH atrial fibrillation (ortholog); bipolar disorder (ortholog); Brain Hypoxia-Ischemia (ortholog); FOUND IN mitochondrial matrix (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: citrate synthase, mitochondrial
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Dog
Squirrel
Pig
Green Monkey
Alliance Orthologs
More Info more info ...
Latest Assembly: Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly
Position:
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21038,028,323 - 38,060,438 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11238,028,468 - 38,057,206 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01232,614,982 - 32,643,719 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11232,867,225 - 32,895,854 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1232,867,225 - 32,895,854 (+)Ensemblpanpan1.1panPan2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
CS
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21038,028,323 - 38,060,438 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11238,028,468 - 38,057,206 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01232,614,982 - 32,643,719 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11232,867,225 - 32,895,854 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1232,867,225 - 32,895,854 (+)Ensemblpanpan1.1panPan2
CS
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381256,271,699 - 56,300,330 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1256,271,699 - 56,300,391 (-)EnsemblGRCh38hg38GRCh38
GRCh371256,665,483 - 56,694,114 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361254,951,750 - 54,980,442 (-)NCBINCBI36Build 36hg18NCBI36
Celera1256,318,264 - 56,346,961 (-)NCBICelera
Cytogenetic Map12q13.3NCBI
HuRef1253,704,180 - 53,732,652 (-)NCBIHuRef
CHM1_11256,632,888 - 56,661,575 (-)NCBICHM1_1
T2T-CHM13v2.01256,239,343 - 56,267,970 (-)NCBIT2T-CHM13v2.0
Cs
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm3910128,173,596 - 128,198,351 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl10128,173,603 - 128,198,348 (+)EnsemblGRCm39 Ensembl
GRCm3810128,337,727 - 128,362,482 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl10128,337,734 - 128,362,479 (+)EnsemblGRCm38mm10GRCm38
MGSCv3710127,774,888 - 127,799,535 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv3610127,740,781 - 127,765,428 (+)NCBIMGSCv36mm8
Celera10130,726,084 - 130,750,750 (+)NCBICelera
Cytogenetic Map10D3NCBI
cM Map1076.53NCBI
Cs
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr871,348,389 - 1,374,624 (+)NCBIGRCr8
mRatBN7.27758,074 - 791,421 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl7758,345 - 791,421 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx73,522,514 - 3,550,877 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.075,398,497 - 5,426,861 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.075,698,983 - 5,725,551 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.072,752,680 - 2,778,963 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl72,752,680 - 2,778,963 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.072,731,092 - 2,757,427 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.471,626,181 - 1,652,197 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.171,626,180 - 1,652,197 (+)NCBI
Celera7639,242 - 663,715 (+)NCBICelera
Cytogenetic Map7q11NCBI
Cs
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554583,881,798 - 3,893,401 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554583,881,798 - 3,913,044 (-)NCBIChiLan1.0ChiLan1.0
CS
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.110584,000 - 611,351 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl10584,904 - 611,436 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha10647,257 - 674,790 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.010592,484 - 620,012 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl10592,484 - 620,005 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.110569,926 - 597,448 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.010812,910 - 840,419 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.010937,007 - 964,321 (-)NCBIUU_Cfam_GSD_1.0
Cs
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494558,165,176 - 58,193,309 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936646678,307 - 692,777 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936646676,926 - 704,988 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
CS
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl521,666,585 - 21,700,711 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1521,669,778 - 21,700,737 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2523,162,491 - 23,186,518 (-)NCBISscrofa10.2Sscrofa10.2susScr3
Pig Cytomap5p12-p13NCBI
CS
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11152,224,667 - 52,253,552 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1152,222,724 - 52,253,307 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666037193,729,868 - 193,761,327 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0


Expression

RNA-SEQ Expression


Sequence


Ensembl Acc Id: ENSPPAT00000050289   ⟹   ENSPPAP00000027449
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl1232,867,225 - 32,895,854 (+)Ensembl
Ensembl Acc Id: ENSPPAT00000050296   ⟹   ENSPPAP00000027456
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl1232,876,893 - 32,894,464 (+)Ensembl
RefSeq Acc Id: XM_003824917   ⟹   XP_003824965
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21038,028,323 - 38,060,438 (+)NCBI
NHGRI_mPanPan11238,028,468 - 38,057,206 (+)NCBI
Mhudiblu_PPA_v01232,614,982 - 32,643,719 (+)NCBI
PanPan1.11232,867,225 - 32,895,854 (+)NCBI
Sequence:
RefSeq Acc Id: XM_008978602   ⟹   XP_008976850
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21038,031,926 - 38,060,438 (+)NCBI
NHGRI_mPanPan11238,028,848 - 38,057,206 (+)NCBI
Mhudiblu_PPA_v01232,615,360 - 32,643,719 (+)NCBI
PanPan1.11232,868,929 - 32,895,852 (+)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_003824965 (Get FASTA)   NCBI Sequence Viewer  
  XP_008976850 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSPPAP00000027449
  ENSPPAP00000027449.1
  ENSPPAP00000027456.1
RefSeq Acc Id: XP_003824965   ⟸   XM_003824917
- Peptide Label: isoform X2
- UniProtKB: A0A2R9BCW0 (UniProtKB/TrEMBL),   A0A2R9BGP8 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_008976850   ⟸   XM_008978602
- Peptide Label: isoform X1
- UniProtKB: A0A2R9BGP8 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSPPAP00000027449   ⟸   ENSPPAT00000050289
Ensembl Acc Id: ENSPPAP00000027456   ⟸   ENSPPAT00000050296


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSPPAG00000036762 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSPPAT00000050289.1 UniProtKB/TrEMBL
  ENSPPAT00000050296.1 UniProtKB/TrEMBL
Gene3D-CATH 1.10.230.10 UniProtKB/TrEMBL
  1.10.580.10 UniProtKB/TrEMBL
InterPro Citrate_synth-like_lrg_a-sub UniProtKB/TrEMBL
  Citrate_synth-like_sm_a-sub UniProtKB/TrEMBL
  Citrate_synthase UniProtKB/TrEMBL
  Citrate_synthase_AS UniProtKB/TrEMBL
  Citrate_synthase_euk UniProtKB/TrEMBL
  Citrate_synthase_sf UniProtKB/TrEMBL
KEGG Report pps:100972419 UniProtKB/TrEMBL
NCBI Gene CS ENTREZGENE
PANTHER CITRATE SYNTHASE, MITOCHONDRIAL UniProtKB/TrEMBL
  PTHR11739 UniProtKB/TrEMBL
Pfam Citrate_synt UniProtKB/TrEMBL
PRINTS CITRTSNTHASE UniProtKB/TrEMBL
PROSITE CITRATE_SYNTHASE UniProtKB/TrEMBL
Superfamily-SCOP SSF48256 UniProtKB/TrEMBL
UniProt A0A2R9BCW0 ENTREZGENE, UniProtKB/TrEMBL
  A0A2R9BGP8 ENTREZGENE, UniProtKB/TrEMBL