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Gene: P2rx6 (purinergic receptor P2X, ligand-gated ion channel, 6) Mus musculus
Symbol: P2rx6
Name: purinergic receptor P2X, ligand-gated ion channel, 6
Description: Predicted to have extracellularly ATP-gated cation channel activity. Predicted to be involved in ion transport and response to ATP. Predicted to localize to several cellular components, including integral component of nuclear inner membrane; parallel fiber to Purkinje cell synapse; and postsynaptic specialization. Is expressed in heart. Orthologous to human P2RX6 (purinergic receptor P2X 6); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 4-hydroxyphenyl retinamide; carbon nanotube.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: ATP receptor; MGC141601; P2rxl1; P2X purinoceptor 6; P2x6; P2xm; purinergic receptor P2X-like 1, orphan receptor
Homo sapiens (human) : P2RX6 (purinergic receptor P2X 6)  HGNC  Alliance
Rattus norvegicus (Norway rat) : P2rx6 (purinergic receptor P2X 6)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : P2rx6 (purinergic receptor P2X 6)
Pan paniscus (bonobo/pygmy chimpanzee) : P2RX6 (purinergic receptor P2X 6)
Canis lupus familiaris (dog) : P2RX6 (purinergic receptor P2X 6)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : P2rx6 (purinergic receptor P2X 6)
Sus scrofa (pig) : P2RX6 (purinergic receptor P2X 6)
Heterocephalus glaber (naked mole-rat) : P2rx6 (purinergic receptor P2X 6)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm38.p6 Ensembl1617,561,885 - 17,577,800 (+)EnsemblGRCm38mm10GRCm38
GRCm381617,561,867 - 17,572,015 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv371617,561,978 - 17,572,105 (+)NCBIGRCm37mm9NCBIm37
MGSCv361617,475,563 - 17,484,828 (+)NCBImm8
Celera1618,135,205 - 18,145,330 (+)NCBICelera
Cytogenetic Map16A3NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on P2rx6
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 11045
Created: 2000-05-25
Species: Mus musculus
Last Modified: 2020-06-30
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.