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Gene: P2rx6 (purinergic receptor P2X 6) Rattus norvegicus
Symbol: P2rx6
Name: purinergic receptor P2X 6
RGD ID: 3243
Description: Exhibits extracellularly ATP-gated cation channel activity. Predicted to be involved in cation transmembrane transport; cell surface receptor signaling pathway; and response to ATP. Localizes to several cellular components, including dendritic spine; neuronal cell body; and postsynaptic density. Orthologous to human P2RX6 (purinergic receptor P2X 6); PARTICIPATES IN calcium/calcium-mediated signaling pathway; INTERACTS WITH 17alpha-ethynylestradiol; 6-propyl-2-thiouracil; ammonium chloride.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: ATP receptor; P2rxl1; P2X purinoceptor 6; P2x6; P2X6 receptor; P2XM; purinergic receptor P2X, ligand-gated ion channel, 6; purinergic receptor P2X-like 1; purinergic receptor P2X-like 1 orphan receptor; purinergic receptor P2X-like 1, orphan receptor; purinergic receptor P2X6; Rnap2x6; RNRNAP2X6
Homo sapiens (human) : P2RX6 (purinergic receptor P2X 6)  HGNC  Alliance
Mus musculus (house mouse) : P2rx6 (purinergic receptor P2X, ligand-gated ion channel, 6)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : P2rx6 (purinergic receptor P2X 6)
Pan paniscus (bonobo/pygmy chimpanzee) : P2RX6 (purinergic receptor P2X 6)
Canis lupus familiaris (dog) : P2RX6 (purinergic receptor P2X 6)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : P2rx6 (purinergic receptor P2X 6)
Sus scrofa (pig) : P2RX6 (purinergic receptor P2X 6)
Heterocephalus glaber (naked mole-rat) : P2rx6 (purinergic receptor P2X 6)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.01187,434,929 - 87,445,221 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1187,435,185 - 87,445,219 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01190,485,985 - 90,496,515 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41185,431,257 - 85,441,293 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11185,471,855 - 85,481,771 (-)NCBI
Celera1182,208,493 - 82,218,517 (-)NCBICelera
Cytogenetic Map11q23NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 6.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
More on P2rx6
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 3243
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2020-08-20
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.