Gene: P2rx6 (purinergic receptor P2X 6) Rattus norvegicus
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Symbol: P2rx6
Name: purinergic receptor P2X 6
Description: Exhibits extracellularly ATP-gated cation channel activity. Involved in protein heterooligomerization. Localizes to several cellular components, including the integral component of postsynaptic specialization membrane; parallel fiber to Purkinje cell synapse; and postsynaptic density. Orthologous to human P2RX6 (purinergic receptor P2X 6); PARTICIPATES IN calcium/calcium-mediated signaling pathway; INTERACTS WITH 17alpha-ethynylestradiol; 6-propyl-2-thiouracil; ammonium chloride.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: ATP receptor; P2rxl1; P2X purinoceptor 6; P2x6; P2X6 receptor; P2XM; purinergic receptor P2X, ligand-gated ion channel, 6; purinergic receptor P2X-like 1; purinergic receptor P2X-like 1 orphan receptor; purinergic receptor P2X-like 1, orphan receptor; purinergic receptor P2X6; Rnap2x6; RNRNAP2X6
Orthologs:
Homo sapiens (human) : P2RX6 (purinergic receptor P2X 6)  HGNC  Alliance
Mus musculus (house mouse) : P2rx6 (purinergic receptor P2X, ligand-gated ion channel, 6)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : P2rx6 (purinergic receptor P2X 6)
Pan paniscus (bonobo/pygmy chimpanzee) : P2RX6 (purinergic receptor P2X 6)
Canis lupus familiaris (dog) : P2RX6 (purinergic receptor P2X 6)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : P2rx6 (purinergic receptor P2X 6)
Sus scrofa (pig) : P2RX6 (purinergic receptor P2X 6)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01187,434,929 - 87,445,221 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01190,485,985 - 90,496,515 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41185,431,257 - 85,441,293 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11185,471,855 - 85,481,771 (-)NCBI
Celera1182,208,493 - 82,218,517 (-)NCBICelera
Cytogenetic Map11q23NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated
RGD Disease Portals

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome

Strain Variation

Strain Sequence Variants (Rnor 5.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on P2rx6
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 3243
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2019-04-23
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.