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Gene: Htr4 (5 hydroxytryptamine (serotonin) receptor 4) Mus musculus
Symbol: Htr4
Name: 5 hydroxytryptamine (serotonin) receptor 4
Description: Predicted to have G protein-coupled serotonin receptor activity. Predicted to be involved in adenylate cyclase-activating G protein-coupled receptor signaling pathway; chemical synaptic transmission; and gamma-aminobutyric acid signaling pathway. Predicted to localize to cytoplasm; dendrite; and integral component of plasma membrane. Is expressed in several structures, including central nervous system; gallbladder; genitourinary system; gut; and retina. Used to study anorexia nervosa. Orthologous to human HTR4 (5-hydroxytryptamine receptor 4); PARTICIPATES IN serotonin signaling pathway via receptors engaging G alphas protein family; INTERACTS WITH 1,2-dichloroethane; 2,2',4,4',5,5'-hexachlorobiphenyl; 2,2',5,5'-tetrachlorobiphenyl.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 5-HT-4; 5-HT4; 5-HT<4L>; 5-hydroxytryptamine receptor 4; 5HTR4; serotonin receptor 4
Homo sapiens (human) : HTR4 (5-hydroxytryptamine receptor 4)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Htr4 (5-hydroxytryptamine receptor 4)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Htr4 (5-hydroxytryptamine receptor 4)
Pan paniscus (bonobo/pygmy chimpanzee) : HTR4 (5-hydroxytryptamine receptor 4)
Canis lupus familiaris (dog) : HTR4 (5-hydroxytryptamine receptor 4)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Htr4 (5-hydroxytryptamine receptor 4)
Sus scrofa (pig) : HTR4 (5-hydroxytryptamine receptor 4)
Chlorocebus sabaeus (African green monkey) : HTR4 (5-hydroxytryptamine receptor 4)
Heterocephalus glaber (naked mole-rat) : Htr4 (5-hydroxytryptamine receptor 4)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm38.p6 Ensembl1862,324,204 - 62,496,577 (+)EnsemblGRCm38mm10GRCm38
GRCm381862,323,546 - 62,503,027 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv371862,483,858 - 62,627,456 (+)NCBIGRCm37mm9NCBIm37
MGSCv361862,449,573 - 62,593,171 (+)NCBImm8
Celera1863,595,586 - 63,739,634 (+)NCBICelera
Cytogenetic Map18E1NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Htr4
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 10750
Created: 2000-05-25
Species: Mus musculus
Last Modified: 2020-07-28
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.